ライフサイエンスコーパス: ionizing radiation

1 cytotoxic chemotherapy, ionizing radiation).

2 hought to be responsible for the bulk of the ionizing radiation.

3 ds from plants exposed to elevated levels of ionizing radiation.

4 ess and a major cause of oxidative stress is ionizing radiation.

5 ge compared to control in cells treated with ionizing radiation.

6 r resistance to cytotoxic chemotherapies and ionizing radiation.

7 as well as increases sensitivity of cells to ionizing radiation.

8 l role in modulating biological responses to ionizing radiation.

9 ic species are known for their resistance to ionizing radiation.

10 ulated but later is strongly up-regulated by ionizing radiation.

11 ch recombination (CSR) and DSBs generated by ionizing radiation.

12 rnatives to current agents that emit harmful ionizing radiation.

13 s normal tissues while sensitizing tumors to ionizing radiation.

14 treatment with the ATR inhibitor AZD6738 and ionizing radiation.

15 gents that increase oxidative damage such as ionizing radiation.

16 tize prostate cancer cells to the effects of ionizing radiation.

17 ect strand break formation in RNA exposed to ionizing radiation.

18 -electrophiles, reactive oxygen species, and ionizing radiation.

19 ent stays, and increased patient exposure to ionizing radiation.

20 to develop molecules that sensitize cells to ionizing radiation.

21 n, and phosphorylation in response to UV and ionizing radiation.

22 of gammaH2AX accumulation was studied after ionizing radiation.

23 ically induced double strand breaks, UVB and ionizing radiation.

24 d negates PIDDosome-mediated apoptosis after ionizing radiation.

25 efined substrates and cellular resistance to ionizing radiation.

26 genomic instability and hypersensitivity to ionizing radiation.

27 aging of body without the use of any harmful ionizing radiation.

28 on of H2AX and cell viability in response to ionizing radiation.

29 ensitivity of the developing embryo/fetus to ionizing radiation.

30 HR and an increased cellular sensitivity to ionizing radiation.

31 tly exposed to imaging examinations that use ionizing radiation.

32 ur center are exposed to very high levels of ionizing radiation.

33 egative consequences of repeated exposure to ionizing radiation.

34 telangiectasia are exquisitely sensitive to ionizing radiation.

35 s and environmental oxidative stress such as ionizing radiation.

36 e, significantly sensitizing cancer cells to ionizing radiation.

37 ions because it does not involve exposure to ionizing radiation.

38 es at relatively low cost without the use of ionizing radiation.

39 ogenitors also are more resistant to H2O2 or ionizing radiation.

40 endoplasmic reticulum stress and exposure to ionizing radiation.

41 (IGF-1R) enhances tumor cell sensitivity to ionizing radiation.

42 s such as that caused by exposure to chronic ionizing radiation.

43 /CT-as it requires exposure to high doses of ionizing radiation.

44 ention of gammaH2AX and Rad51 foci following ionizing radiation.

45 effects arising from environmental gases and ionizing radiation.

46 ( 1.40 eV) on samples previously exposed to ionizing radiation.

47 nic RAS and reduced tissue inflammation upon ionizing radiation.

48 ection of the direct and indirect effects of ionizing radiation.

49 1 associates with gamma-H2A.X in response to ionizing radiation.

50 repair pathways and increases sensitivity to ionizing radiation.

51 tors of GSC quiescence following exposure to ionizing radiation.

52 y, with high diagnostic accuracy and without ionizing radiation.

53 hibitor hydroxyurea, but not the DSB inducer ionizing radiation.

54 for dosimetry, including high sensitivity to ionizing radiation (20 times that of Al2O3:C, under the

55 Among these, ionizing radiation, a non-thermal process, has gained co

56 t (perhaps all) anticancer drugs, as well as ionizing radiation, affect autophagy.

57 o exhibit significantly enhanced survival of ionizing radiation and bleomycin treatment, agents that

58 sponse to double-strand DNA breaks caused by ionizing radiation and chemotherapeutic agents.

59 caspase-3 in oral cancer cells treated with ionizing radiation and chemotherapeutic drug, paclitaxel

60 essed in cancer cells, confers resistance to ionizing radiation and chemotherapy agents, and promotes

61 the diversity of tumour cellular response to ionizing radiation and establish multiple lines of evide

62 Melanin pigments protect against both ionizing radiation and free radicals and have potential

63 Thymidine radical cation (1) is produced by ionizing radiation and has been invoked as an intermedia

64 The absence of ionizing radiation and high resolution MRI, along with t

65 ession of abscopal tumours in the context of ionizing radiation and immune checkpoint blockade in viv

66 ely formed when triglycerides are exposed to ionizing radiation and is being widely used as marker si

67 s the advantages of real-time imaging and no ionizing radiation and may obviate the need for the pati

68 letion leads to the increased sensitivity to ionizing radiation and poly (ADP-ribose) polymerase inhi

69 nd ATP production observed after exposure to ionizing radiation and reduced DNA repair.

70 n laboratory mice after parental exposure to ionizing radiation and show irradiation markedly alters

71 own to differ for exposures like smoking and ionizing radiation and simple cumulative exposure does n

72 ool to map the amount of the body exposed to ionizing radiation and the location of exposure, which a

73 ed, of which 408 (22%) involved considerable ionizing radiation and were the focus of investigation.

74 this patient showed increased sensitivity to ionizing radiations and phleomycin, attesting to a proba

75 mutants however display hypersensitivity to ionizing radiation, and combination of rpa1c and rpa1e r

76 ection, increases HR and cell survival after ionizing radiation, and prevents cellular senescence.

77 ization and activation in cells treated with ionizing radiation, and that loss of Mdm2 Ser394 phospho

78 Oxidative and genotoxic stresses caused by ionizing radiation are detrimental to healthy tissues bu

79 ave irradiation, mechano-chemistry or highly ionizing radiations are employed.

80 adiation absorption of tumors, high doses of ionizing radiations are often needed during RT, leading

81 ease, associated with exposures to high-dose ionizing radiation, are well known.

82 ascorbate enhances the cytotoxic effects of ionizing radiation as seen by decreased cell viability a

83 the knowledge of the effects of exposure to ionizing radiation as well as questions related to respo

84 Currently, therapies aimed at ameliorating ionizing radiation-associated toxicities are limited.

85 es alters patterns of DNA damage repair from ionizing radiation at a gene locus-specific and genome-w

86 In response to ionizing radiation, ATM phosphorylates FBXW7 at serine 2

87 ized neuronal progenitors to apoptosis after ionizing radiation because of excessive DNA damage.

88 cores are known to emit very high levels of ionizing radiation, becoming visible over intergalactic

89 of medical imaging which involve the use of ionizing radiation but not for ultrasonography.

90 hat could only be formed through exposure to ionizing radiation, but not by any other means of physic

91 n increase the ability of E. coli to survive ionizing radiation by a factor of 1000.

92 ant fraction of mammalian cells treated with ionizing radiation can survive despite caspase-3 activat

93 Ionizing radiation comes from a variety of sources, incl

94 irectly from a human population, that MF non-ionizing radiation could have adverse biological impacts

95 ) and 5,6-dihydrothymidine (dHT), formed via ionizing radiation damage to 2'-deoxycytidine and thymid

96 6-dihydro-2'-deoxyuridine (dHdU), formed via ionizing radiation damage to cytosine under anoxic condi

97 rafts, pharmacologic ascorbate combined with ionizing radiation decreased tumor growth and increased

98 with the combination of an AKT inhibitor and ionizing radiation decreased tumor size in a p53-deficie

99 High-linear energy transfer ionizing radiation, derived from high charge (Z) and ene

100 ganic materials have been mainly proposed as ionizing radiation detectors in the indirect conversion

101 ile opening the door to new possibilities in ionizing-radiation detectors.

102 NEK1 is essential for the ionizing radiation DNA damage response and priming of th

103 the notion that survival after high doses of ionizing radiation does not depend on a single mechanism

104 es were subjected, for a week, to cumulative ionizing radiation doses, as used during cancer treatmen

105 opoietic dysfunction results from a range of ionizing radiation doses.

106 allows for precise and instant detection of ionizing radiations down to the level of 10(-4) Gy, repr

107 n this article, we show that DSBs induced by ionizing radiation, etoposide, or bleomycin suppress Rag

108 Substantial evidence has linked ionizing radiation exposure (RE) to oncogenesis.

109 on whether the linear no-threshold model of ionizing radiation exposure accurately predicts the subs

110 Accidental or deliberate ionizing radiation exposure can be fatal due to widespre

111 However, recent concerns about ionizing radiation exposure have led to a search for alt

112 egeneration and increases survival following ionizing radiation exposure in mice.

113 signatures of somatic mutation characterize ionizing radiation exposure irrespective of tumour type.

114 raphy may have harms resulting from low-dose ionizing radiation exposure or identification of extraco

115 The knowledge of ionizing radiation exposure risks among the medical staf

116 Although MRE avoids ionizing radiation exposure, it remains costly.

117 These findings, plus an absence of ionizing radiation exposure, mean that CMR should be mor

118 )J recombination and sensitizes the cells to ionizing radiation exposure.

119 hat AIM2 may be a new therapeutic target for ionizing radiation exposure.

120 dren and adolescents from potential risks of ionizing radiation exposure.

121 uted tomography (CT) owing to concerns about ionizing radiation exposure.

122 eutics aimed at mitigating the toxicities of ionizing radiation exposure.

123 nt new method with high accuracy and without ionizing radiation exposure.

124 imaging, however, comes with risk related to ionizing radiation exposure.

125 man lymphocytes proportional to TP53 status (ionizing radiation exposure: patients with LFS, 2.71% [9

126 Nuclear medicine uses ionizing radiation for both in vivo diagnosis and therap

127 galaxies probably facilitated the escape of ionizing radiation from galaxies when the Universe was a

128 imaging of both radionuclide- and beam-based ionizing radiation from high-energy photons and charged

129 Thus, ionizing radiation generates distinctive mutational sign

130 he genetic consequences of human exposure to ionizing radiation has been a long-standing goal of huma

131 Ionizing radiation has been shown to produce negative ef

132 human tissues following in vivo exposure to ionizing radiation have not been documented.

133 antly more susceptible to strand scission by ionizing radiation (hydroxyl radical) than is DNA.

134 date novel epigenetic rheostats that promote ionizing radiation hypersensitivity in various normal st

135 As with other ionizing radiation imaging modalities, CBCT imaging shou

136 Here, we searched for signatures of ionizing radiation in 12 radiation-associated second mal

137 eptible to cataract induction by exposure to ionizing radiation in early postnatal age, when lens epi

138 sms acting to buffer the negative effects of ionizing radiation in natural populations.

139 methanol-based - interstellar model ices to ionizing radiation in the form of energetic electrons.

140 ssociated gene (ATDC) mediated resistance to ionizing radiation in vitro and in vivo in mouse xenogra

141 ions about its role in DNA damage induced by ionizing radiation, in which low-energy electrons are kn

142 llow (Hirundo rustica) nestlings to low dose ionizing radiation increased genetic damage to their per

143 Herein, we show that ionizing radiation increases high mannose-type N-glycans

144 Exposure to ionizing radiation increases the risk of chronic metabol

145 ficient to repress the apoptotic response to ionizing radiation independent of developmental signalin

146 and persistence of gammaH2AX foci following ionizing radiation, indicating a defect in DNA double-st

147 High doses of ionizing radiation induce acute damage to epithelial cel

148 induced DNA damage, and RAD51 recruitment to ionizing radiation induced foci (IRIF), which requires e

149 Moreover, ionizing radiation induced macrophage morphological alte

150 We found that cranial ionizing radiation induced robust and durable PMT in tum

151 1 overexpression suppresses the formation of ionizing radiation-induced 53BP1 and BRCA1 but not RNF16

152 thosterol 5-desaturase, then UVR accelerates ionizing radiation-induced BCC carcinogenesis.

153 , chronic topical application of D3 inhibits ionizing radiation-induced BCC tumorigenesis.

154 Bs, which in normal cells is responsible for ionizing radiation-induced cell senescence and protectio

155 X functions together with XLF in response to ionizing radiation-induced complex DSBs, whereas they fu

156 en implicated the yejH gene in the repair of ionizing radiation-induced damage.

157 ofluorescent detection of repair proteins at ionizing radiation-induced DNA damage foci that Wwox exp

158 Ionizing radiation-induced DNA double-strand breaks (DSB

159 ese two proteins and variably contributes to ionizing radiation-induced DSB repair in human and chick

160 sensitive technique to monitor external-beam ionizing radiation-induced DSBs in peripheral blood lymp

161 (TIRR) that specifically associates with the ionizing radiation-induced foci formation region of 53BP

162 tem cells exhibit reduced ATM activation and ionizing radiation-induced foci, they display apoptotic

163 opment of therapeutics capable of mitigating ionizing radiation-induced hematopoietic toxicity could

164 nucleosome (50-500 bp) scale, obtained using ionizing radiation-induced spatially correlated cleavage

165 irst, Plk3 and CtIP enhance the formation of ionizing radiation-induced translocations; second, they

166 Consequently, NHEJ-dependent repair of ionizing-radiation-induced DNA double-strand breaks is c

167 Acute exposure to ionizing radiation induces massive cell death and severe

168 ecombination (HR) factors BRCA1 and RAD51 at ionizing radiation (IR) -induced foci.

169 ocyst perturbation resulted in resistance to ionizing radiation (IR) and accelerated resolution of DN

170 eaks are the major lethal lesions induced by ionizing radiation (IR) and can be efficiently repaired

171 mediate ATM kinase signaling in response to ionizing radiation (IR) and chromatin changes, respectiv

172 we challenged Plk1-overexpressing mice with ionizing radiation (IR) and found that Plk1-overexpressi

173 ency enhances accumulation of p53 induced by ionizing radiation (IR) and sensitizes mice to IR-induce

174 ivation and repression events in response to ionizing radiation (IR) and synthetic p53 activation.

175 r responses to genotoxic stresses, including ionizing radiation (IR) and topoisomerase inhibitors.

176 Induction of DNA damage by ionizing radiation (IR) and/or cytotoxic chemotherapy is

177 s (GSCs) to survive exposure to low doses of ionizing radiation (IR) as a model of adult stem cell in

178 Treatment with ionizing radiation (IR) can lead to the accumulation of

179 Ionizing radiation (IR) causes not only acute tissue dam

180 mal thyroid function is disturbed because of ionizing radiation (IR) exposure, deleterious effects ca

181 In response to ionizing radiation (IR) induced DNA damage, cancer cells

182 Exposure of murine and human tissues to ionizing radiation (IR) induces the expression of p16(IN

183 Nonlethal exposure to ionizing radiation (IR) is a public concern due to its k

184 Ionizing radiation (IR) is also an immune modulator and

185 Ionizing radiation (IR) is commonly used in cancer thera

186 We studied the effect of ionizing radiation (IR) on continuous growth of seven hE

187 However, the effects of ionizing radiation (IR) on HKG expression is unclear.

188 ogaster germline and midgut are resistant to ionizing radiation (IR) or chemically induced apoptosis

189 Elderly cancer patients treated with ionizing radiation (IR) or chemotherapy experience more

190 discrete foci in response to DSBs induced by ionizing radiation (IR) or radiomimetic drugs, including

191 l of cancer cells mediated by high levels of ionizing radiation (IR) reduces the effectiveness of rad

192 forts to understand the complex phenotype of ionizing radiation (IR) resistance, a genome sequence ca

193 melanogaster larvae irradiated with doses of ionizing radiation (IR) that kill about half of the cell

194 s typically insulted during chemotherapy and ionizing radiation (IR) therapy and disposed to mucositi

195 Concern over potential exposures of ionizing radiation (IR) to large populations has emphasi

196 lved in sensitizing radioresistant tumors to ionizing radiation (IR) treatments while minimizing inju

197 isite sensitivity of mitotic cancer cells to ionizing radiation (IR) underlies an important rationale

198 h-MYCN/Trp53(KI/KI) tumors were resistant to ionizing radiation (IR), as expected.

199 In response to ionizing radiation (IR), cells activate a DNA damage res

200 ses of HuR in oral cancer cells treated with ionizing radiation (IR), determined that HuR cleavage pr

201 ed cell survival after DNA damage induced by ionizing radiation (IR), expression of BRCA1 K898E prove

202 uction of NADPH, such that after exposure to ionizing radiation (IR), there were higher levels of rea

203 cterial cells to survive extreme exposure to ionizing radiation (IR), we broadly screened nonessentia

204 es mediating the response of glioblastoma to ionizing radiation (IR), we used polysome profiling to d

205 e, we show that clinically relevant doses of ionizing radiation (IR)-induce cellular invasion of ErbB

206 g pharmacological strategies for controlling ionizing radiation (IR)-induced cell death is important

207 genomic instability and cell sensitivity to ionizing radiation (IR)-induced death.

208 Ionizing radiation (IR)-induced DNA double-strand breaks

209 broblasts (MEFs) showed defects in repairing ionizing radiation (IR)-induced DNA double-strand breaks

210 religate transformed linear plasmids, repair ionizing radiation (IR)-induced DSBs in nonreplicating c

211 RC5A contributes significantly to preventing ionizing radiation (IR)-induced lung tumorigenesis.

212 ent study, we report for the first time that ionizing radiation (IR)-induced MMP-9 enhances SDC1 shed

213 scarce and the mutational processes defining ionizing radiation (IR)-induced mutagenesis in vivo are

214 s accumulate more alkylator-induced, but not ionizing radiation (IR)-induced, mutations than similarl

215 In this study, we demonstrate that ionizing radiation (IR)-induces ATM-dependent phosphoryl

216 k, in cells treated with small molecules and ionizing radiation (IR).

217 drugs have been found to sensitize cells to ionizing radiation (IR).

218 the ability to alter cellular sensitivity to ionizing radiation (IR).

219 o a hyperphosphorylated state in response to ionizing radiation (IR).

220 tance to radiotherapy limits the efficacy of ionizing radiation (IR).

221 t in exposure to potentially lethal doses of ionizing radiation (IR).

222 complex new phenotype, extreme resistance to ionizing radiation (IR).

223 (EGFR) can enhance the cytotoxic effects of ionizing radiation (IR).

224 rvival following cytotoxic stress induced by ionizing radiation (IR).

225 ry response elicited in mouse macrophages by ionizing radiation (IR).

226 sence sensitizes the bacterium to killing by ionizing radiation (IR).

227 e hypersensitive to genotoxic stress such as ionizing radiation (IR).

228 tion to the severity of dystrophy induced by ionizing radiation (IR).

229 emination in adjacent brain parenchyma after ionizing radiation (IR).

230 bility to repair DNA in the cells exposed to ionizing radiation (IR).

231 Ionizing radiation is a common therapeutic modality and

232 Ionizing radiation is a potent carcinogen, inducing canc

233 Ionizing radiation is a well known human carcinogen.

234 ing the consequences of exposure to low dose ionizing radiation is an important public health concern

235 ortance of nontargeted (systemic) effects of ionizing radiation is attracting increasing attention.

236 Ionizing radiation is frequently used to kill tumor cell

237 minimizing exposure to alkylating agents and ionizing radiation is important for optimizing survival

238 Ionizing radiation is one of the most common cancer trea

239 l method for imaging mineral content without ionizing radiation is proposed.

240 Magnetic field (MF) non-ionizing radiation is widespread and everyone is exposed

241 ren may be more vulnerable to the effects of ionizing radiation, it is necessary to develop methods t

242 llographic and Raman analysis indicates that ionizing radiation kick-starts both peroxide decompositi

243 The burden of low-dose ionizing radiation (LDIR) exposure from medical procedur

244 re exposed to increasing amounts of low-dose ionizing radiation (LDIR) from cardiac procedures.

245 eas around Chernobyl differing in background ionizing radiation levels and one control study site in

246 ormation and an increase of metal depletion, ionizing radiations, marine eutrophication, and particul

247 stem cells (HSCs) are highly susceptible to ionizing radiation-mediated death via induction of ROS,

248 Ionizing radiation-mediated tumor regression depends on

249 factor XLF result in extreme sensitivity for ionizing radiation, microcephaly, and growth retardation

250 the cellular response of tumours exposed to ionizing radiation, modelling the alteration of oxygen p

251 he long-term risk of cancer from exposure to ionizing radiation, most participants reported that thei

252 main clinical mainstays, optical readouts of ionizing radiation offer numerous benefits and complemen

253 nding that cancer chemotherapeutic drugs and ionizing radiation often promote autophagy has provided

254 Particularly, the effect of ionizing radiation on macrophages, using therapeutically

255 , we test for the consequence of exposure to ionizing radiation on plant development.

256 d that independently assessed the effects of ionizing radiation on transcription and post-transcripti

257 ts normal cells from DNA damage induction by ionizing radiation or chemotherapeutics, whereas cancer

258 that arises spontaneously or secondarily to ionizing radiation or chronic lymphoedema.

259 specific environmental mutagen, specifically ionizing radiation or cigarette smoking.

260 ere we report that treatment of tumours with ionizing radiation or genotoxic drugs drives p21-activat

261 ic CRAF inhibitor sensitizes tumour cells to ionizing radiation or genotoxic drugs.

262 inflammatory challenges, such as exposure to ionizing radiation or to bacterial lipopolysaccharides.

263 e induced by a variety of stimuli, including ionizing radiation, oxidative stress, and inflammation.

264 is concerning owing to the cancer risk from ionizing radiation, particularly in children younger tha

265 molecular probes sensitive to byproducts of ionizing radiation (primarily reactive oxygen species, o

266 Ionizing radiation produces clustered damage to DNA whic

267 Whereas ionizing radiation promoted autophagy in all tumor cell

268 lpha-imaging systems: an alpha-camera and an ionizing-radiation quantum imaging detector (iQID) camer

269 he common access to imaging methods based on ionizing radiation requires also radiation protection.

270 ouse B-cell line, and dispensable for normal ionizing radiation resistance in both G1-arrested and cy

271 dividuals with PPM1D truncating mutations to ionizing radiation resulted in normal p53 activation, su

272 r studying biological effects under low-dose ionizing radiation, safety control in medical radiation

273 NHEJ and sensitizes nonreplicating cells to ionizing radiation, selective ablation of the ligase act

274 Importantly, LRF loss restores ionizing radiation sensitivity to p53 null cells, making

275 Ionizing radiation significantly increased PS exposure o

276 Furthermore, for ionizing radiation sources that cannot be imaged using t

277 of melanized fungi to cosmic and terrestrial ionizing radiation suggests that melanin also plays a pi

278 lasts from these pigs were more sensitive to ionizing radiation than non-SCID piglets, eliminating th

279 r carcinogenic effect compared with sparsely ionizing radiation that is prevalent on earth.

280 damage caused by exogenous sources, such as ionizing radiation, the tumour suppressor p53 mediates c

281 As it is altered by ionizing radiation, the vascular network is considered a

282 Increasing evidence suggests that ionizing radiation therapy (RT) in combination with chec

283 n the precisely guided delivery of high-dose ionizing radiation to an intracranial target.

284 nction and show that SNP309G cooperates with ionizing radiation to exacerbate tumor development.

285 dy to E-cadherin, works synergistically with ionizing radiation to promote the epidermal damage.

286 therapy and precisely deliver high doses of ionizing radiation to small deep-seated target volumes.

287 We find that UVR exposure of ionizing radiation-treated Ptch1(+/-) mice accelerates B

288 ed the function of miR-24 in NPC cells after ionizing radiation treatment, resulting in increased apo

289 chemical agents that increase DNA damage by ionizing radiation under O2-deficient conditions.

290 h yejH and radA hypersensitized the cells to ionizing radiation, UV and ciprofloxacin damage, indicat

291 s to agents that cause double-strand breaks (ionizing radiation, UV radiation, ciprofloxacin).

292 BSGI on the basis of the Biologic Effects of Ionizing Radiation VII report, the benefit-to-radiation

293 ch of the Committee on Biological Effects of Ionizing Radiation VII.

294 Exposure to ionizing radiation was estimated to be 14.5 mSv for one

295 udy, stimulation by doxorubicin, hypoxia and ionizing radiation was used to induce MDR in HCC cells.

296 and dehydroascorbic acid (DHAA), induced by ionizing radiation, was investigated.

297 N109D) mutant RUNX1 conferred resistance to ionizing radiation when overexpressed in Ba/F3 cells und

298 Densely ionizing radiation, which is present in the space radiat

299 The galaxy is leaking ionizing radiation with an escape fraction of about 8 pe

300 There are well-known associations of ionizing radiation with female breast cancer, and emergi