ライフサイエンスコーパス: ionone

1 no impact on other terpene alcohols or beta-ionone.

2 hibitor corallidictyal D starting from alpha-ionone.

3 DA): beta-damascenone, beta-ionone and alpha-ionone.

4 amine receptors, and the opsin agonist, beta-ionone.

5 O2), converts xanthophylls to rosafluene and ionones.

6 to verify the model: 1-phenylethanol, alpha-ionone, 3-methyl-1-indanone, o-(chloromethyl)phenyl sulf

7 analysis showed a > or =50% decrease in beta-ionone (a beta-carotene-derived C13 cyclohexone) and a >

8 the 9,10 (9',10') bonds and generating beta-ionone, although beta-cyclocitral resulting from a 7,8 (

9 ation and minor quantities of 5,6-epoxy-beta-ionone and 5,6-epoxy-4-oxo-beta-apo-11-carotenal, no oth

10 ilution assay (SIDA): beta-damascenone, beta-ionone and alpha-ionone.

11 f carotenoids at the 9'-10' bond to yield an ionone and an apo-10'-carotenoid.

12 e of ripening, whereas the changes for alpha-ionone and beta-ionone were not obvious.

13 d with extremely high concentrations of beta-ionone and binding did not alter the structure of rhodop

14 ols, volatile phenols and pantolactone; beta-ionone and herbaceous nuances were in higher proportions

15 while diethyl succinate, decanoic acid, beta-ionone, and citronellol concentration were not changed w

16 nzyl isothiocyanate, 1-hexen-3-one, (E)-beta-ionone, and methyl benzoate were the most odour-active c

17 quantification of beta-damascenone and beta-ionone, and the crucial influence of ethanol content of

18 rod rhodopsin is also expected to bind beta-ionone at sufficiently high concentrations because the b

19 losteric binding site for retinoid, but beta-ionone binds to the latter type of rhodopsin with low af

20 angle down-apo-beta-carotenal (C27) and beta-ionone (C13).

21 , v/v) and of an apolar mixture made of beta-ionone, (+/-)-citronellal, (+)-limonene, and flavone dis

22 ate, beta-damascone, beta-damascenone, and a-ionone, contributing nutty, sweet floral attributes to t

23 sults indicate that PhCCD1 activity and beta-ionone emission are likely regulated at the level of tra

24 beta-Ionone emission by flowers occurred principally during d

25 nd alpha-terpineol) and norisoprenoids (beta-ionone), especially when the CIS temperature was set at

26 ,6-nonadienal, geraniol, phenylethanol, beta-ionone, hotrienol and dihydroactinidiolide to be odour a

27 linalool oxides, (E)-2-hexenal, phytol, beta-ionone, hotrienol, methylpyrazine and methyl salicylate

28 an enzyme responsible for formation of beta-ionone in tomato.

29 ylate cyclase agonist), and conversely, beta-ionone-induced cell death could be blocked by cotreatmen

30 in (a G protein inhibitor) also blocked beta-ionone-induced cell death.

31 biosynthesis of the (+)-enantiomer of alpha-ionone is favoured equally, whichever MJ stereoisomer us

32 One such volatile, beta-ionone, is important to fragrance in many flowers, inclu

33 n of isorhodopsin or by incubation with beta-ionone (opsin agonist) killed 19-30% of rod cells.

34 ated that the truncated retinal analog, beta-ionone, partitioned into the membranes of green-sensitiv

35 was an enhanced uptake of four or more beta-ionones per rhodopsin.

36 ion of (13)C nuclei introduced into the beta-ionone ring (at the C16, C17, and C18 methyl groups) and

37 site and a specific orientation of the beta-ionone ring above the plane of the heme consistent with

38 ion in the dark, and that motion of the beta-ionone ring allows Trp265(6.48) and transmembrane helix

39 ening of the steric restraints near the beta-ionone ring and SB ends of the chromophore, (ii) displac

40 d 7',8' double bonds adjacent to a 3-OH-beta-ionone ring and that the conversion of zeaxanthin to cro

41 rds, indicating that the opening of the beta-ionone ring and the increase of chromophore extension in

42 termine the relative orientation of the beta-ionone ring and the polyene chain of the chromophore 11-

43 etinal C6-C7 single bond connecting the beta-ionone ring and the retinylidene chain is 6-s-cis in bot

44 strong steric interactions between its beta-ionone ring and transmembrane helices H5 and H6, while d

45 The beta-ionone ring can rotate relative to the polyene chain, th

46 these bleaching intermediates shows that the ionone ring cross-links to tryptophan-265 on helix F in

47 l's polyene chain and separation of its beta-ionone ring from Trp-265.

48 ggested that at least one unsubstituted beta-ionone ring half-site was imperative for efficient cleav

49 In particular, we find that the beta-ionone ring has a twisted 6-s-cis conformation, whereas

50 can infer whether or not the pigment's beta-ionone ring has left its binding site.

51 G identified recently encoding the 2,2'-beta-ionone ring hydroxylase that further hydroxylate astaxan

52 ase and the crtZ gene encoding the 3,3'-beta-ionone ring hydroxylase that were responsible for astaxa

53 strain, while torsional twisting of the beta-ionone ring is maintained.

54 Most surprisingly, the beta-ionone ring is mobile within its binding pocket; interac

55 tion to the crtW gene encoding the 4,4'-beta-ionone ring ketolase and the crtZ gene encoding the 3,3'

56 hat represent the polyene chain and the beta-ionone ring of retinal.

57 rise from weakened interaction with the beta-ionone ring of the chromophore following cis-to-trans is

58 on alters the interaction of Trp265 with the ionone ring of the retinal chromophore.

59 e protein at van der Waals distance from the ionone ring of the retinal.

60 In particular, the beta-ionone ring of the retinylidene inverse agonist is cruci

61 The current view that the beta-ionone ring of the rhodopsin chromophore vacates its bin

62 ps of either carbon C(1) or C(5) of the beta-ionone ring or carbon C(9) of the polyene chain.

63 e hydroxyl-bearing amino acids near the beta-ionone ring part of the retinal in opsin, A164S, F261Y,

64 nal; we find that Trp265 moves away from the ionone ring prior to any conformational transition.

65 rization, the (2)H NMR data suggest the beta-ionone ring remains in its hydrophobic binding pocket in

66 ds (Ser164, Tyr261, and Thr269) close to the ionone ring that lower the transition energy by interact

67 efining the relative orientation of the beta-ionone ring to the polyene chain has both modest barrier

68 lices H3 and H5 by the C5-methyl of the beta-ionone ring.

69 l twisting of the polyene chain and the beta-ionone ring.

70 an ordered cholesterol molecule and the beta-ionone ring.

71 tenoids with at least one unsubstituted beta-ionone ring.

72 rms a cap on the pocket occupied by the beta-ionone ring.

73 roxylases attach hydroxyl groups to the beta-ionone rings (beta-rings) of carotenoid substrates, resu

74 bind, as do truncated retinoids in the beta-ionone series.

75 mary melanocytes with the OR51E2 ligand beta-ionone significantly inhibited melanocyte proliferation.

76 Our results further showed that beta-ionone stimulates melanogenesis and dendritogenesis.

77 flavor compounds (2-methyisoborneol and beta-ionone), suggesting a cyanobacterial origin.

78 plants led to a 58% to 76% decrease in beta-ionone synthesis in the corollas of selected petunia lin

79 crystallography revealed binding of one beta-ionone to bovine green-sensitive rod rhodopsin.

80 Beta-ionone was easily identified by the high-throughput scre

81 hereas the changes for alpha-ionone and beta-ionone were not obvious.

82 ral nuances (with the only exception of beta-ionone) were in higher proportions.

83 ase of certain odorants (e.g. linalool, beta-ionone), while flavonoids showed the opposite effect, de

84 prouting was significantly increased by beta-ionone with concomitant increases in cAMP, pCREB, and sy