ライフサイエンスコーパス: iron deficiency

1 ysfunction as a consequence of cardiomyocyte iron deficiency.

2 n content is an effective strategy to reduce iron deficiency.

3 letion reduced cell viability in response to iron deficiency.

4 distribution to the cytoplasm in response to iron deficiency.

5 esis, was also downregulated by hypoxia with iron deficiency.

6 ng medication use and the subsequent risk of iron deficiency.

7 n patients with HF and often associated with iron deficiency.

8 modifications during both erythropoiesis and iron deficiency.

9 ange of pseudomonads to enhance growth under iron deficiency.

10 orld's population; half the cases are due to iron deficiency.

11 is a common strategy to prevent or overcome iron deficiency.

12 in disease manifestations in the setting of iron deficiency.

13 Twenty-three infants had latent iron deficiency.

14 ce, a phenotype that becomes more evident in iron deficiency.

15 on absorption from hemoglobin in response to iron deficiency.

16 sorptive capacity that occurs in response to iron deficiency.

17 virtually all microorganisms in response to iron deficiency.

18 d for storage as ferritin, is greater during iron deficiency.

19 dividuals reverses the protective effects of iron deficiency.

20 ciated with an increased subsequent risk for iron deficiency.

21 er of complexity to the cell's adaptation to iron deficiency.

22 pose that COPT2 could play a dual role under iron deficiency.

23 re donation-related symptoms, deferrals, and iron deficiency.

24 ociated with an increased subsequent risk of iron deficiency.

25 exercise capacity in patients with HFrEF and iron deficiency.

26 patients with pre-existing risk factors for iron deficiency.

27 petrobactin (fpbNOPQ) are induced to prevent iron deficiency.

28 FRO2 locus associated with root length under iron deficiency.

29 se medications increase the risk of clinical iron deficiency.

30 ortening in high copper conditions and under iron deficiency.

31 iron markers were consistent with functional iron deficiency: 134 patients (89.3%) were hypoferremic,

32 Iron deficiency affects 40%-50% of pregnancies.

33 1, involved in iron uptake, caused neuronal iron deficiency, age-progressive degeneration of a subse

34 imtomax had excellent diagnostic accuracy in iron deficiency anaemia and was comparable to convention

35 in 133 prospectively recruited patients with iron deficiency anaemia attending for a gastroscopy.

36 ogy of 153 patients presenting to a separate iron deficiency anaemia clinic were retrospectively revi

37 We cannot exclude that the correction of iron deficiency anaemia is in some part due to the treat

38 entation is complicated by observations that iron deficiency anaemia protects against falciparum mala

39 nal guidelines recommend coeliac serology in iron deficiency anaemia, and duodenal biopsy for those t

40 ysiology, diagnosis, and acute management of iron deficiency anaemia, and outstanding research questi

41 fy any causes other than coeliac disease for iron deficiency anaemia, suggesting that biopsy avoidanc

42 onic diseases are frequently associated with iron deficiency anaemia--notably chronic kidney disease,

43 classic red cell indices in the diagnosis of iron deficiency anaemia.

44 non-compliance and ineffective correction of iron-deficiency anaemia.

45 symptoms in patients with heart failure and iron deficiency and also warrants further study.

46 ding to increased hepcidin levels triggering iron deficiency and anemia starting in utero.

47 lly significant after adjusting for baseline iron deficiency and anemia status overall (adjusted RR,

48 YSL6 dramatically reduces plant tolerance to iron deficiency and decreases chloroplastic iron content

49 observations reporting protective effects of iron deficiency and harmful effects of iron administrati

50 epcidin expression occurs physiologically in iron deficiency and increased erythropoiesis but is path

51 anemia-control programs should address both iron deficiency and infections.

52 n to be effective in preventing and treating iron deficiency and iron deficiency anemia in infants an

53 h studies, particularly in the evaluation of iron deficiency and its associated anemia in pregnancy a

54 Iron deficiency and malaria have similar global distribu

55 tment is the standard of care for concurrent iron deficiency and malaria.

56 Both iron deficiency and overload impinge negatively on cardi

57 Iron deficiency and poor linear growth are common in inf

58 regnant women are particularly vulnerable to iron deficiency and related adverse pregnancy outcomes a

59 atory states can induce hepcidin production, iron deficiency, and anemia.

60 ferential diagnosis of thalassemia trait and iron deficiency, and in monitoring therapeutic response

61 vels at 12 months of age and ferritin level, iron deficiency, and iron deficiency anemia at 8 and 12

62 In multivariable pooled models, child age, iron deficiency, and stunting independently predicted an

63 smodium and Schistosoma infections, cellular iron deficiency, and stunting were significantly negativ

64 kidney; reduced red blood cell survival and iron deficiency; and mineral bone disease caused by dist

65 n Southeast Asia, Thalassemia trait (TT) and iron deficiency anemia (IDA) are the two most common ane

66 Although the hazards associated with iron deficiency anemia (IDA) are well known, concerns ab

67 Iron deficiency anemia (IDA) has detrimental effects on

68 tinal workup fails to establish the cause of iron deficiency anemia (IDA) in a substantial proportion

69 Routine screening and supplementation for iron deficiency anemia (IDA) in asymptomatic, nonanemic

70 on between Helicobacter pylori infection and iron deficiency anemia (IDA) in humans.

71 gastritis-induced achlorhydria is a cause of iron deficiency anemia (IDA) in humans.

72 Preoperative iron deficiency anemia (IDA) occurs frequently; however

73 The prevalence of iron deficiency (ID) and iron deficiency anemia (IDA) was 10-32% and 2-5%, respec

74 based on iron biomarker concentrations were iron deficiency anemia (IDA), anemia of inflammation (AI

75 nemia at delivery, and 25% (n = 5) developed iron deficiency anemia (IDA).

76 and about half of this burden is a result of iron deficiency anemia (IDA).

77 deficiency (ID; diminished iron stores) and iron deficiency anemia (IDA; poor iron stores and dimini

78 Iron deficiency anemia afflicts 1 in 3 individuals, most

79 to his gastroenterologist for evaluation of iron deficiency anemia and weight loss.

80 age and ferritin level, iron deficiency, and iron deficiency anemia at 8 and 12 months of age.

81 RR, 0.48; 95% CI, 0.32-0.70) and the risk of iron deficiency anemia by 66% (RR, 0.34; 95% CI, 0.19-0.

82 eraction at the locus, impacting the risk of iron deficiency anemia in African Americans with specifi

83 The treatment of iron deficiency anemia in children with inflammatory bow

84 preventing and treating iron deficiency and iron deficiency anemia in infants and young children.

85 for pregnant women or routine screening for iron deficiency anemia in pregnant women or young childr

86 lance of benefits and harms of screening for iron deficiency anemia in pregnant women to prevent adve

87 In particular, iron deficiency anemia is a major global health issue, b

88 Iron deficiency anemia is common and consequential in no

89 Iron deficiency anemia is one of the most serious forms

90 during early development in iron-refractory iron deficiency anemia patients, who present with microc

91 nd clinical trial in adults with NDD-CKD and iron deficiency anemia to compare the safety and efficac

92 pcidin levels for diagnosing iron-refractory iron deficiency anemia to global health applications suc

93 f iron status across the full continuum from iron deficiency anemia to iron deficiency to iron replet

94 Post administration of FCM, correction of iron deficiency anemia was observed with improved mean h

95 practical improvements in the management of iron deficiency anemia, a disorder that may affect as ma

96 ong-standing type II diabetes, hypertension, iron deficiency anemia, aortic stenosis, and prior baria

97 h outcomes that are associated with maternal iron deficiency anemia, both Canada and the United State

98 e anemia of chronic disease, iron refractory iron deficiency anemia, cancer, hereditary hemochromatos

99 women who are malnourished, have symptoms of iron deficiency anemia, or have special hematologic cond

100 1%, 32.7%) to 6.8% (95% CI: 4.2%, 9.3%), and iron deficiency anemia, which was 6.2% (95% CI: 3.0%, 9.

101 PRSS6, whose mutations cause iron refractory iron deficiency anemia.

102 t challenge the entrenched oral treatment of iron deficiency anemia.

103 he United States who do not have symptoms of iron deficiency anemia.

104 l disorders had been treated for concomitant iron deficiency anemia.

105 nmol/L; P<0.05) and low in one patient with iron deficiency anemia.

106 n and appeared to be effective in correcting iron deficiency anemia.

107 s and underlies erythropoietic repression in iron deficiency anemia.

108 12 months of age in infants at high risk for iron deficiency anemia.

109 eople worldwide whose inadequate diet causes iron deficiency anemia.

110 e to be a safe and efficacious treatment for iron deficiency anemia.

111 Iron-deficiency anemia (IDA) affects millions of persons

112 ts and young children in Sub-Saharan Africa, iron-deficiency anemia (IDA) is common, and many complem

113 nical study compared 96 female patients with iron-deficiency anemia and 60 healthy female control sub

114 nt deficiency among children worldwide, with iron-deficiency anemia associated with long-term adverse

115 rum ferritin levels and a lower incidence of iron-deficiency anemia at 4-6 months of age.

116 She had a history of iron-deficiency anemia due to long-standing celiac disea

117 Patients with iron-deficiency anemia had a significantly reduced choro

118 India's high prevalence of iron-deficiency anemia has largely been attributed to th

119 ren in low and middle income countries where iron-deficiency anemia is highly prevalent.

120 Iron-deficiency anemia was the top cause globally, altho

121 gastrointestinal blood loss, and unexplained iron-deficiency anemia), and the performance of selected

122 hildren aged 9 to 48 months with nutritional iron-deficiency anemia, ferrous sulfate compared with ir

123 eed on blood in the small intestine, causing iron-deficiency anemia, malnutrition, growth and develop

124 thickness (CT) in the eyes of patients with iron-deficiency anemia, the most common form of the anem

125 reditary hemochromatosis and iron-refractory iron-deficiency anemia.

126 ally important biomarker in diseases such as iron-deficiency anemia.

127 ted patients with unexplained, mild, chronic iron-deficiency anemia.

128 be considered for children with nutritional iron-deficiency anemia.

129 black woman has heavy menstrual bleeding and iron-deficiency anemia.She reports nocturia and urinary

130 Both anemia and iron deficiency are associated with an increase in all-c

131 measures that target parasitic diseases and iron deficiency are needed.

132 ssays and transcriptomics we discovered that iron deficiency arising from KCNE2-dependent achlorhydri

133 de nanoparticles have been used for treating iron deficiency, as contrast agents for magnetic resonan

134 elayed umbilical cord clamping (CC) prevents iron deficiency at 4 to 6 months of age, but long-term e

135 n significantly reduced the risk of maternal iron deficiency at delivery by 52% (RR, 0.48; 95% CI, 0.

136 amatergic terminals in the rodent with brain iron deficiency (BID), a pathogenetic model of restless

137 TaMATE1B expression in roots was induced by iron deficiency but not by phosphorus deficiency or alum

138 y important in relation to the management of iron deficiency but should also inform dietary advice, e

139 nt African women and is predominantly due to iron deficiency, but antenatal iron supplementation has

140 Malaria itself may contribute to iron deficiency, but the impact of an interruption in ma

141 Fortified foods can reduce iron deficiency, but whether they can also reduce zinc d

142 75 mg/kg) and attenuated in the presence of iron deficiency by dichloroacetate and imatinib, 2 putat

143 vate RNR in response to genotoxic stress and iron deficiency by facilitating redistribution of its sm

144 63 women, 403 children) to assess changes in iron deficiency (children only) and anemia.

145 ne for the genetic studies of abiotic stress iron deficiency chlorosis (IDC) of soybean is reported.

146 together with their ability for reduction of iron deficiency chlorosis were explored.

147 Americans (AAs) have a greater prevalence of iron deficiency compared with European Americans.

148 proportion of iron-responsive anemia due to iron deficiency compared with iron-unresponsive anemia d

149 In children, iron deficiency declined from 26.9% (95% CI: 21.1%, 32.7

150 ed the proportion of anemia with concomitant iron deficiency (defined as an inflammation-adjusted fer

151 ical trial of patients with HFrEF (<40%) and iron deficiency, defined as a serum ferritin level of 15

152 It contrasted 77,046 patients with new iron deficiency diagnoses (January 1999-December 2013),

153 Clinical iron deficiency disturbs normal responses to hypoxia, as

154 of porphyria, suggesting that mitochondrial iron deficiency does not result in an accumulation of pr

155 regnant women are particularly vulnerable to iron deficiency due to the high iron demands of pregnanc

156 Delayed cord clamping (DCC) can prevent iron deficiency during the first 6 months of life.

157 During iron deficiency, elevated copper levels are observed in

158 These data demonstrate that iron deficiency enhances H. pylori virulence and represe

159 and specificities of 97%, 100%, and 97% for iron deficiency (ferritin <15 ng/mL or 32 pmol/L), vitam

160 Vitamin D and iron deficiencies frequently co-exist.

161 mong patients without known risk factors for iron deficiency, gastric acid inhibitor use for >/=2 yea

162 Infants with latent iron deficiency had significantly prolonged wave V laten

163 In utero latent iron deficiency has been associated with abnormal neurod

164 r lack of iron, in part because detection of iron deficiency has required a blood sample.

165 ajor Ca(2)(+) pump and the acquired state of iron deficiency, have been associated with protection fr

166 Under conditions of iron deficiency, hepcidin expression is reduced to promo

167 Among participants with HFrEF with iron deficiency, high-dose oral iron did not improve exe

168 Individuals with absolute iron deficiency (ID) and an iron-replete (IR) control gr

169 Both iron deficiency (ID) and excess can lead to impaired hea

170 he distribution of TBI and the prevalence of iron deficiency (ID) and ID anemia (IDA) among toddlers,

171 The prevalence of iron deficiency (ID) and iron deficiency anemia (IDA) wa

172 Iron deficiency (ID) and vitamin D deficiency (VDD) are

173 Iron deficiency (ID) anemia is a prevalent disease, yet

174 aternal iron status (at 2M) predicted infant iron deficiency (ID) at 5M.

175 Iron deficiency (ID) before the age of 3 y can lead to l

176 African Americans are at increased risk of iron deficiency (ID) but also have higher serum ferritin

177 This merits attention because iron deficiency (ID) during pregnancy is associated with

178 s to adjust for inflammation on estimates of iron deficiency (ID) in low- and high-infection-burden s

179 Iron deficiency (ID) is a major cause of anemia, along w

180 Iron deficiency (ID) is an urgent public health problem

181 Iron deficiency (ID) is common in young children aged 6-

182 Iron deficiency (ID) is independently associated with an

183 ambodian women, current reports suggest that iron deficiency (ID) prevalence is low.

184 Clinical diagnosis of iron deficiency (ID) through sampling of bone marrow to

185 The diagnosis of iron deficiency (ID) through SF concentration, the most

186 Guidelines on the diagnosis and treatment of iron deficiency (ID) vary widely across indications.

187 21 South African children (aged 6-11 y) with iron deficiency (ID) were randomly divided into 4 groups

188 n regulation in global health contexts where iron deficiency (ID), anemia, and high infectious burden

189 icant and its absorption may be increased in iron deficiency (ID).

190 Poor iron status, including iron deficiency (ID; diminished iron stores) and iron de

191 rrent hereditary hemorrhagic telangiectasia: iron deficiency impairs hypoxemia compensations by restr

192 with intravenous FCM in patients with HF and iron deficiency improves iron stores.

193 ransport protein, functions under copper and iron deficiencies in Arabidopsis (Arabidopsis thaliana).

194 commendations on the treatment of anemia and iron deficiency in adult patients with heart disease.

195 able malaria transmission, the prevalence of iron deficiency in children decreased significantly afte

196 on plants display enhanced susceptibility to iron deficiency in comparison to the wild type.

197 up new biotechnological approaches to fight iron deficiency in crops.

198 tion of intracellular iron and mitochondrial iron deficiency in cultured mammalian cells, as well as

199 associations, and consequences of anemia and iron deficiency in epidemiologically representative outp

200 overy opens new avenues for the treatment of iron deficiency in humans, one of the most common and wi

201 weight (LBW) (</=2500 g) is associated with iron deficiency in infancy and high blood pressure (BP)

202 Prevention of iron deficiency in infancy may promote neurodevelopment.

203 Prevention of iron deficiency in infancy may promote neurodevelopment.

204 0%, 55%, and 58% of children had concomitant iron deficiency in low-, medium-, high-, and very high-i

205 hemselves may be an effective way to address iron deficiency in malaria-endemic areas.

206 of the microRNA miR-130a is up-regulated by iron deficiency in mice.

207 rect abnormally high hepcidin expression and iron deficiency in MT2(-/-) mice.

208 to use means for point-of-care screening for iron deficiency in resource-limited settings lacking lab

209 e in root iron uptake and content along with iron deficiency in shoots.

210 Induction of moderate iron deficiency increases erythroblasts number, reduces

211 Our data suggest that iron deficiency increases liver miR-130a, which, by targ

212 double mutant does not up- and down-regulate iron deficiency-induced and -repressed genes.

213 t components of such strategies, we analyzed iron deficiency-induced changes in the transcriptome of

214 s grafted to ysl1ysl3 shoots do not initiate iron deficiency-induced gene expression, indicating that

215 lix-loop-helix transcription factor FER-LIKE IRON DEFICIENCY-INDUCED TRANSCRIPTION FACTOR (FIT).

216 ch has lost the ability to properly regulate iron deficiency-influenced gene expression in both roots

217 emphasizes the complex relationship between iron deficiency, iron treatment, and malaria infection i

218 BRINDA findings confirm that iron deficiency is a common and consistent risk factor f

219 Iron deficiency is a leading cause of anemia in sub-Saha

220 Iron deficiency is a major global public health problem

221 Iron deficiency is also among the most common nutritiona

222 s a leading cause of childhood morbidity and iron deficiency is among the most prevalent nutritional

223 Latent iron deficiency is associated with abnormal auditory neu

224 ice that the increased liver miR-130a during iron deficiency is associated with reduced liver Alk2 mR

225 Iron deficiency is common in obese subjects.

226 Iron deficiency is common in overweight and obese indivi

227 Iron deficiency is common in patients with heart failure

228 The accurate estimation of iron deficiency is important in planning and implementin

229 We hypothesized that iron deficiency is involved in the pathogenesis of pulmo

230 odia or in countries where the prevalence of iron deficiency is low and genetic hemoglobin disorders

231 Iron deficiency is present in approximately 50% of patie

232 Iron deficiency is present in approximately 50% of patie

233 Iron deficiency is the most common cause.

234 Iron deficiency is the most common micronutrient deficie

235 Iron deficiency is the most common nutrient deficiency w

236 Iron deficiency is thought to be one of the most prevale

237 in malaria transmission on the prevalence of iron deficiency is unknown.

238 detection of serum ferritin, a biomarker for iron deficiency, is presented.

239 In iron deficiency, liver BMP-SMAD signaling and hepcidin a

240 ession analysis was conducted for each group.Iron deficiency, malaria, breastfeeding, stunting, under

241 Therefore, rectifying iron deficiency may attenuate disease among H. pylori-in

242 signaling provides a mechanism through which iron deficiency may be detrimental to human health.

243 reased resistance to simultaneous copper and iron deficiencies, measured as reduced leaf chlorosis an

244 ss is known about the effects of hypoxia and iron deficiency on hepatic gluconeogenesis.

245 o be sensitive to the effects of gestational iron deficiency on memory function in infants and young

246 To define the influence of iron deficiency on microbial virulence in gastric carcin

247 cord clamping has not been shown to prevent iron deficiency or anemia after 6 months of age.

248 its and may also cause clinical syndromes of iron deficiency or excess.

249 oration of the detrimental effects of either iron deficiency or overload.

250 ) levels in live cells and mice experiencing iron deficiency or overload.

251 Remarkably, apo-pyoverdine abolished the iron-deficiency phenotype and restored the growth of pla

252 Iron deficiency prevalence (ferritin <12 mug/L, or <30 m

253 he functional and prognostic significance of iron deficiency, randomized multicenter trials exploring

254 l gastrectomy and one an adenocarcinoma) and iron-deficiency rather than megaloblastic anaemia.

255 Current guidelines to treat iron deficiency recommend daily provision of ferrous iro

256 oposed to help clinicians diagnose and treat iron deficiency, recommending oral iron in the first tri

257 Most iron deficiency reflects an inadequate supply of iron in

258 Despite its known detrimental effects, iron deficiency remains the most common micronutrient de

259 2 and human ferritins in yeast activated the iron deficiency response and increased iron deposition i

260 ssion of PCBP3 and -4 in yeast activated the iron deficiency response, but only PCBP3 exhibited stron

261 th POPEYE (PYE), a positive regulator of the iron deficiency response.

262 riptional regulatory network involved in the iron deficiency response.

263 previously shown to be a major target of the iron deficiency response.

264 ter IRT1 and FRO2 in roots, indicative of an iron-deficiency response.

265 snx mutants exhibited enhanced iron deficiency responses compared with the wild type, p

266 ed in the regulation of Arabidopsis thaliana iron deficiency responses, we identified the members of

267 e independent of the shoot control over root iron deficiency responses.

268 Hypoxia, and more so hypoxia with iron deficiency, results in hypoglycemia due to decrease

269 data suggest that ZPP may be appropriate for iron deficiency screening; further investigation is warr

270 red and compared between infants with latent iron deficiency (serum ferritin </=75 ng/mL) and infants

271 , and genetic defects in the pathogenesis of iron deficiency should have a strong impact on the curre

272 ng that loss of pH control contributes to an iron deficiency signal in the mutant.

273 ty consecutive infants with risk factors for iron deficiency, such as small for gestational age and m

274 Erythropoiesis and iron deficiency suppress hepcidin via erythroferrone-dep

275 ates hepcidin suppression by erythropoietin, iron deficiency, thalassemia, and hemochromatosis.

276 Worldwide, more individuals have iron deficiency than any other health problem.

277 Laboratory tests defining iron deficiency, the recognition of developmental delays

278 te deficiencies were not.The contribution of iron deficiency to anemia varies according to a country'

279 ull continuum from iron deficiency anemia to iron deficiency to iron replete to iron excess, 3) the l

280 Down-regulation of FPS also triggered an iron-deficiency transcriptional response that is consist

281 ron application, citrate supplementation and iron deficiency treatment, indicate that the shoot-direc

282 the search for and treatment of the cause of iron deficiency, treatment strategies encompass preventi

283 At baseline, prevalence of iron deficiency was 9% on the basis of a low serum ferri

284 Neither acute nor chronic iron deficiency was able to alter the association of Tmp

285 Iron deficiency was consistently associated with anemia

286 Iron deficiency was evident from depleted iron stores (d

287 Depending on the definition applied, iron deficiency was present in 270 (43.2%) to 425 (68.0%

288 At 8 months, the risk for iron deficiency was reduced in the delayed clamping grou

289 ificity of optical non-invasive detection of iron deficiency were 97% and 90%, respectively.

290 al diabetes, and 30 without risk factors for iron deficiency were enrolled.

291 Chief among these is iron deficiency, which is commonly present due to concur

292 The response to iron deficiency, which is known to strongly induce couma

293 A coordinate response to iron deficiency, which leads to dismantling of the photo

294 H. pylori infection is also associated with iron deficiency, which similarly augments gastric cancer

295 Whether correction of iron deficiency with (intravenous) ferric carboxymaltose

296 The prevalence of iron deficiency with anemia (hemoglobin <11.0 g/dL) decl

297 ents with a history suggestive of hereditary iron deficiency with serum ferritin higher than expected

298 ith off-label use of deferasirox to maintain iron deficiency, with successful results.

299 Iron deficiency without anemia is prevalent in patients

300 We therefore hypothesized that clinical iron deficiency would disturb integrated human responses