ライフサイエンスコーパス: iron deposition

1 2G6 are inconsistently associated with brain iron deposition.

2 e on the follow-up scans, suggesting chronic iron deposition.

3 <0.001), and Perls stain confirmed localized iron deposition.

4 recruited macrophages at the site of chronic iron deposition.

5 her NAS, even among patients without hepatic iron deposition.

6 xed HC/reticuloendothelial system cell (RES) iron deposition.

7 pcidin and ferritin and increased hepatocyte iron deposition.

8 odies and delineate histological features of iron deposition.

9 not sensitive enough to detect early cardiac iron deposition.

10 ng an environment favorable for extrahepatic iron deposition.

11 38 patients and in nine of 25 patients with iron deposition.

12 normal collagen accumulation, and remarkable iron deposition.

13 ers has been cardiac disease from myocardial iron deposition.

14 ng a declining role of the peroxo complex in iron deposition.

15 cession images within CMI likely result from iron depositions.

16 sistent with oxidative stress, HbG increased iron deposition, 4-hydroxynonenal and 8-hydroxydeoxyguan

17 A SF >1.5 x ULN is associated with hepatic iron deposition, a diagnosis of NASH, and worsened histo

18 an family with a pallido-pyramidal syndrome, iron deposition and cerebellar atrophy, we identified a

19 logic conditions suitable for future cardiac iron deposition and complementary information to liver a

20 ia major and sickle cell disease can lead to iron deposition and damage to the heart, liver, and endo

21 nts with NAFLD is associated with greater HC iron deposition and decreased serum hepcidin levels, and

22 The overall process of iron deposition and detoxification by LiDps is described

23 Increased iron deposition and evidence of oxidative damage have al

24 s examining the relationship between hepatic iron deposition and histological severity in nonalcoholi

25 ular renal injury was accompanied by nonheme iron deposition and hypoxia-inducible factor-1alpha upre

26 to examine the relationship between hepatic iron deposition and liver histology in 849 patients enro

27 To date, the link between the iron deposition and malignant ventricular arrhythmias in

28 utation type is associated with Kupffer-cell iron deposition and normal transferrin saturation in viv

29 ggest that the CR-induced benefit of reduced iron deposition and preserved motor function may indicat

30 ggest that the CR-induced benefit of reduced iron deposition and preserved motor function may indicat

31 iated virus (AAV)-ADIPOQ ameliorated cardiac iron deposition and restored cardiac function in iron-ov

32 quantitatively evaluated for diffuse hepatic iron deposition and siderotic regenerative nodules to as

33 elationship between the grade and pattern of iron deposition and the clinical, laboratory, and histol

34 Histology was used to assess iron deposition and to examine relationships between iro

35 f both the HEPH and CP genes leads to kidney iron deposition and toxicity, MCFs could protect kidney

36 resonance imaging can be used as a marker of iron deposition and yields incremental information towar

37 ht be attributable to microglial activation, iron deposition, and blood-brain barrier breakdown.

38 worsened neurological recovery, exacerbated iron deposition, and decreased alternative activation of

39 Massive ascites, iron deposition, and high body mass index were additiona

40 HFE genotype, serum hepcidin level, hepatic iron deposition, and histology in nonalcoholic fatty liv

41 rin bound iron (NTBI), produces acute tissue iron deposition, and initiates inflammation.

42 multi-organ dysfunction caused by increased iron deposition, and is treatable if detected early.

43 ithout reperfusion hemorrhage led to chronic iron deposition, and the extent of this deposition was s

44 relationship between the presence of hepatic iron deposition, apoptosis, histologic features, and ser

45 Iron deposition appeared on day 3 around the haematoma b

46 The presence and pattern of hepatic iron deposition are associated with distinct histologica

47 mus with signs of extensive phagocytosis and iron deposition around plaque-like amyloid deposition.

48 Hfe (-/-) mice had considerable parenchymal iron deposition as well, in a pattern similar to that ob

49 progressive MS is consistent with increased iron deposition, as corroborated by other techniques.

50 ubular brush border loss, diminished tubular iron deposition, blocked the development of interstitial

51 halassemia major (TM), suggesting myocardial iron deposition, but it is unknown at what age this occu

52 The extent of iron deposition ([Fe]) within each sample was measured u

53 that the assessment of dissolved atmospheric iron deposition fluxes and their effect on the biogeoche

54 Crystallized iron deposition from PMO is directly related to proinfla

55 Subjects with hepatic iron deposition had higher serum hepcidin levels than su

56 The SMA liver is dark red, small and has: iron deposition; immature sinusoids congested with blood

57 tion of dietary iron, and patterns of tissue iron deposition in agreement with clinical observations

58 id precursors with perinuclear mitochondrial iron deposition in bone marrow.

59 characterized by pathological mitochondrial iron deposition in erythroid precursors.

60 mochromatosis (GH) is associated with excess iron deposition in hepatocytes, which results in progres

61 our understanding of the natural history of iron deposition in hereditary hemochromatosis.

62 er transferrin saturation and more prominent iron deposition in liver parenchyma in vivo, retained ir

63 own that Hjv-/- mice have markedly increased iron deposition in liver, pancreas, and heart but decrea

64 ion of dietary iron absorption and excessive iron deposition in major organs of the body.

65 In summary, the localization of iron deposition in MS and AD brains indicates potential

66 HC iron deposition in NAFLD is also associated with OS and

67 Previously, we found appreciable hepatic iron deposition in one third of our patients undergoing

68 The frequency of HCC in patients with iron deposition in regenerative nodules (52% [37 of 71 p

69 MR imaging can enable detection of iron deposition in regenerative nodules as a possible ri

70 rence of HCC may be associated causally with iron deposition in regenerative nodules in patients with

71 eposition was seen in 79 (40%) patients, and iron deposition in regenerative nodules was seen in 71 (

72 he liver and increased serum iron levels and iron deposition in several organs similar to classic her

73 s absorption of dietary iron and progressive iron deposition in several tissues, particularly liver.

74 s absorption of dietary iron and progressive iron deposition in several tissues, particularly liver.

75 erized by excess dietary iron absorption and iron deposition in several tissues.

76 duced TLR4-dependent hepcidin expression and iron deposition in splenic macrophages, findings mirrore

77 g, evidence of both significant increases in iron deposition in subcortical GM and myelin degeneratio

78 ion of significant, voxel-level increases in iron deposition in subcortical gray matter (GM) of patie

79 mutation in the iron-regulatory pathways and iron deposition in the brain resulting in neurodegenerat

80 Histologic studies showed marked iron deposition in the cortex and outer medulla accompan

81 athologically by neuronal loss, gliosis, and iron deposition in the globus pallidus, red nucleus, and

82 progressive movement disorder and prominent iron deposition in the globus pallidus.

83 although the CR group had significantly less iron deposition in the GP, SN, red nucleus, and temporal

84 although the CR group had significantly less iron deposition in the GP, SN, red nucleus, and temporal

85 The iron deposition in the mutant mice was predominantly hep

86 Iron deposition in the pancreas and heart occurred after

87 set of liver transplant patients with marked iron deposition in their cirrhotic liver who developed s

88 ferrioxamine does not prevent excess cardiac iron deposition in two-thirds of patients with thalassae

89 psy tissue have demonstrated the presence of iron depositions in white matter lesions.

90 ts of the HFE knockout mice showed increased iron deposition, increased content of reactive oxygen sp

91 Brain iron deposition increases normally with age, especially

92 New evidence also suggests that hepatic iron deposition increases the risk of HCC in NASH-derive

93 the spatiotemporal relationships among PMO, iron deposition, infarct resorption, and left ventricula

94 s studied to further define the mechanism of iron deposition inside the protein and the role of LiDps

95 d the iron deficiency response and increased iron deposition into ferritin.

96 e2+/HoSF ratio), H2O2 is not produced during iron deposition into HoSF using O2 as an oxidant.

97 in both DRG neurons and cardiomyocytes, and iron deposition is detected in cardiomyocytes after 1 ye

98 n rates are high but the rate of atmospheric iron deposition is low.

99 Patients with iron deposition limited to hepatocytes had a lower propo

100 riable analysis, only body mass index, liver iron deposition, massive ascites, and use of 3.0 T were

101 univariate analysis, body mass index, liver iron deposition, massive ascites, use of 3.0 T, presence

102 ormal excitability and heterogeneous cardiac iron deposition may cause the arrhythmogenesis of human

103 of aging, motor performance speed and brain iron deposition measured in vivo using magnetic resonanc

104 of aging, motor performance speed and brain iron deposition measured in vivo using MRI, to determine

105 etrospectively determine the effect of liver iron deposition on the evaluation of liver fat by using

106 model, were used to determine the effect of iron deposition on the Spearman correlation coefficient

107 ion, IgG extravasation, heme oxygenase (HO), iron deposition, oxidative end products (4-hydroxynonena

108 such correlation was found in patients with iron deposition (r = 0.1 for reader 1, r = -0.31 for rea

109 ned liver fat percentage in patients without iron deposition (r = 0.7 for reader 1, r = 0.6 for reade

110 g that H2O2 is a quantitative product of the iron deposition reaction with O2 as an oxidant, even tho

111 8.0 to determine if H2O2 is a product of the iron deposition reaction.

112 l recessive disorder characterized by tissue iron deposition secondary to excessive dietary iron abso

113 t as the adiponectin-mediated attenuation of iron deposition was abolished in PPARalpha-knockout mice

114 Iron deposition was accompanied by hepatocyte injury and

115 Liver iron deposition was found in 25 of 38 patients.

116 Although iron deposition was observed in all iron-injected fish,

117 Hepatic parenchymal iron deposition was seen in 79 (40%) patients, and iron

118 No iron deposition was seen in aortas of the wild-type nona

119 Increased iron deposition was seen in FRDA heart, liver and spleen

120 ratio of GRE images in patients with hepatic iron deposition was significantly lower than that in pat

121 steady-state free precession as a marker of iron deposition was validated in a canine MI model (n=18

122 Liver fat percentage and presence of iron deposition were independently recorded by a patholo

123 al transport of iron is impaired, leading to iron deposition which in the presence of reactive oxygen

124 of hepcidin signaling in ALD leads to liver iron deposition, which is a major contributing factor to

125 erve large glacial-interglacial contrasts in iron deposition, which we infer reflects strongly changi

126 Recent canines studies have shown that iron deposition within chronic myocardial infarction (CM

127 Iron deposition within the iron storage protein ferritin

128 emorrhagic myocardial infarction can lead to iron depositions within the infarct zones, which can be

129 We postulated that pancreatic iron deposition would precede cardiac iron loading, repr