ライフサイエンスコーパス: iron regulatory protein 2

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1 nism by which heme can regulate the level of iron regulatory protein 2.

2 protein 1 (also known as IRP1 and Aco1) and iron regulatory protein 2 (also known as IRP2 and Ireb2)

3 igase complex that mediates the stability of iron regulatory protein 2, an important posttranscriptio

4 atory protein 1, increased protein levels of iron regulatory protein 2, and resulted in abnormal punc

5 the expression of transferrin receptor 1 and iron regulatory protein 2 consistent with decreased iron

6 Iron regulatory protein 2 contains a domain not present

7 Iron regulatory protein 2 coordinates cellular regulatio

8 Iron regulatory protein 2 coordinates the cellular regul

9 lated neurodegeneration has been reported in iron regulatory protein 2-deficient (IRP2 -/-) mice coin

10 es and controls iron homeostasis through the iron regulatory protein-2 in human cell lines.

11 cient erythropoietic tissues of mice lacking iron regulatory protein 2, in iron-deficient murine eryt

12 Three SNPs in the iron regulatory protein 2 (IREB2) gene met this stringen

13 Genetic ablation of iron regulatory protein 2 (IRP-2), a protein responsible

14 eficient cells revealed increased binding of iron regulatory protein 2 (IRP2) and decreased binding o

15 pletion, as indicated by increased levels of iron regulatory protein 2 (IRP2) and/or increased IRE-bi

16 Iron regulatory protein 2 (IRP2) controls the synthesis

17 The degradation of iron regulatory protein 2 (IRP2) in iron-replete cells i

18 Iron regulatory protein 2 (IRP2) is a central regulator

19 Iron regulatory protein 2 (IRP2) is a key iron sensor th

20 Iron regulatory protein 2 (IRP2) is an RNA-binding prote

21 Here, we demonstrate that iron regulatory protein 2 (IRP2) plays a key role in iro

22 The first is that overexpression of iron regulatory protein 2 (IRP2) recapitulates many aspe

23 lated tightly in mammalian cells, in part by iron regulatory protein 2 (IRP2), a protein that is degr

24 ate covalently modifies cysteine residues on iron regulatory protein 2 (IRP2), rendering it unable to

25 ter regulators of iron metabolism, including iron regulatory protein 2 (IRP2).

26 ional regulation of iron metabolism genes by iron regulatory protein 2 (IRP2).

27 /6 mice and mice with a targeted deletion of iron regulatory protein 2 (IRP2-/-) that have been repor

28 iron, and to stimulate the expression of the iron regulatory protein-2 (IRP2), which increases the in

29 eceptor-interacting protein 1, Hemo-oxidized iron regulatory protein 2 ligase 1 (HOIL-1), HOIL-1-inte

30 he catalytic core component is heme-oxidized iron regulatory protein 2 ubiquitin ligase-1-interacting

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