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   1 of epigenetic and genetic processes to these irreversible changes.                                   
  
  
     4  that involves freezing and thawing leads to irreversible changes due to phase changes and water cond
     5 fferentiating keratinocytes, possibly due to irreversible changes effected by cell envelope barrier f
  
  
     8 ggregates formed on wire surfaces undergo an irreversible change in structure when exposed to elevate
  
  
  
    12 ic rabbits (n = 6) but caused only small and irreversible changes in activity in normal rabbits (n = 
    13 nounced than in younger animals, pointing to irreversible changes in aging zebrafish radial glia.    
    14 ive and have a poor long-term prognosis with irreversible changes in airway architecture leading to m
  
  
    17  compression reduces this burden but creates irreversible changes in images, potentially impairing de
  
  
    20 d zeta potential and secondary structure and irreversible changes in tertiary structure of capsid pro
  
    22 tical properties of solutions and the small, irreversible changes in the conductivity of films in the
    23 disappearance of fitness optima that lead to irreversible changes in the location of a population in 
    24 o aggregated particles in solution and large irreversible changes in the morphology of films accompan
  
    26 hows that thermal disruption of LDL involves irreversible changes in the particle morphology and prot
    27 tron with the 60S ribosomal subunit leads to irreversible changes in the sedimentation profile of thi
    28  fibrous networks composed of fibrin utilize irreversible changes in their hierarchical structure at 
  
  
  
  
  
    34 etic state, prolonged suppression results in irreversible changes that compromise their developmental
    35 able from wild-type animals, indicating that irreversible changes to the DNA of olfactory neurons do 
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