ライフサイエンスコーパス: irritability

1 st step in the processes of 'sentience' and 'irritability'.

2 ued all study drugs due to an adverse event (irritability).

3 and libido, and with anorexia, fatigue, and irritability.

4 ying the sensitisation of C-fibres in airway irritability.

5 disordered breathing and reduces ventricular irritability.

6 tems related to anger, worry, dysphoria, and irritability.

7 ious mood symptoms, ie, sadness, crying, and irritability.

8 stories of impulsive aggressive behavior and irritability.

9 es were associated with decreasing levels of irritability.

10 ver, tachycardia, poor perfusion, and severe irritability.

11 pattern associated with abnormal electrical irritability; 13 patients had abnormal nerve conduction

12 nt) with depression (20%), apathy (15%), and irritability (15%) being most common.

13 .001), anxiety (3.00; 2.01-4.48; P < .001), irritability 2.99; 2.11-4.22; P < .001), and depression

14 crocephaly (41%), nausea and vomiting (30%), irritability (24%), and lethargy (21%) for children aged

15 performed in 45 patients with mTBI (38 with irritability, 32 with depression, and 18 with anxiety).

16 (48%), fatigue (46%), drowsiness (39%), and irritability (37%); most scores indicated high distress.

17 ), disinhibition (16% versus 2%, P = 0.009), irritability (48% versus 9%, P = 0.0001), sleep changes

18 stic specificity in the neural correlates of irritability, a symptom of both DMDD and bipolar disorde

19 Depression, irritability/aggression and OCBs are prevalent in all st

20 Obsessive/compulsive behaviours and irritability/aggression were inversely correlated with t

21 five neuropsychiatric features: depression, irritability/aggression, obsessive/compulsive behaviours

22 Youths with irritability also show maladaptive orienting to, interpr

23 vioral and psychophysiological correlates of irritability among children with severe mood dysregulati

24 ed in a sustained reduction in scores on the Irritability and Aggression subscales of the Overt Aggre

25 Given that psychiatric changes, including irritability and aggression, are common findings in HD p

26 dications are indicated for the treatment of irritability and agitation symptoms in children with aut

27 important findings if the pathophysiology of irritability and anxiety are studied in isolation.

28 Specifically, irritability and anxiety jointly influenced left amygdal

29 The child's irritability and anxiety were rated by both parent and c

30 s analyses, the shared and unique effects of irritability and anxiety were tested on amygdala functio

31 2 major dimensions of child psychopathology, irritability and anxiety, on neural responses to facial

32 They are frequently used to treat irritability and associated behaviors including aggressi

33 The authors highlight irritability and callous behavior as two core exemplars

34 amine how the relation is affected by infant irritability and caregiving practices.

35 symptoms, including depressed mood, anxiety, irritability and craving in dependent subjects may contr

36 ) was significantly higher than that between irritability and delinquency (r(A)=0.57, 95% CI=0.45-0.6

37 ) was significantly higher than that between irritability and delinquency (r(A)=0.57, 95% CI=0.45-0.6

38 ic analyses, the genetic correlation between irritability and depression (r(A)=0.70, 95% CI=0.59-0.82

39 ic analyses, the genetic correlation between irritability and depression (r(A)=0.70, 95% CI=0.59-0.82

40 unted for by the genetic association between irritability and depression at wave 2.

41 the hypothesis that the association between irritability and depression is accounted for by genetic

42 y exacerbate, or even cause symptoms such as irritability and depression that are common in early sta

43 al effects underlie the relationship between irritability and depression.

44 nd bipolar disorder showed similar levels of irritability and did not differ from each other or from

45 uana relapse and reversed withdrawal-related irritability and disruptions in sleep and food intake (p

46 Irritability and fear/anxiety may be additional clinical

47 tween the two components of oppositionality (irritability and headstrong/hurtful behaviors) and depre

48 roversy exists regarding whether nonepisodic irritability and hyperarousal (severe mood dysregulation

49 severe mood dysregulation (i.e., nonepisodic irritability and hyperarousal without episodes of euphor

50 e narrower phenotypes the symptoms of severe irritability and hyperarousal.

51 (PTE) affected speech processing, levels of irritability and hypertonicity, attention levels, abilit

52 the genetic and environmental influences on irritability and its overlap with depression.

53 side effects experienced by women using HC (irritability and lability) are not captured by a screeni

54 thic electromyogram with abnormal electrical irritability and muscle biopsy findings of myofibrillar

55 Irritability and psychoticlike symptoms at entry were si

56 t of children exhibiting chronic nonepisodic irritability and severe temper outbursts.

57 bacute encephalopathy with motor regression, irritability and stupor or coma resulting in major handi

58 that is, those who have severe, nonepisodic irritability and the hyperarousal symptoms characteristi

59 py was significantly predictive of change in irritability and verbal and direct assault.

60 s known about genetic influences on juvenile irritability and whether such influences are development

61 Irritability and/or anxiety influenced amygdala connecti

62 .95), owing to the elimination of the items "irritability" and "agitation."

63 motionality (increased stress reactivity and irritability) and addictive behaviors.

64 equate growth, reduced reporting of colic or irritability, and a lower frequency of antibiotic use.

65 ron therapy include myalgias, fever, nausea, irritability, and depression.

66 rted high levels of household strain, social irritability, and financial strain as well as limitation

67 Mood symptoms--anxiety, irritability, and mood lability--had the lowest coeffici

68 Three mood symptoms--anxiety, irritability, and mood lability--were the most stable sy

69 , respectively, including fatigue, insomnia, irritability, and rash/pruritus.

70 sion, anger-hostility, dissociation, "limbic irritability," and drug use.

71 ies as well as moderately strong links among irritability (anger), concentration deficits, and sleep

72 -sectional investigations and indicates that irritability/anger during MDEs is a highly prevalent cli

73 Overt irritability/anger was present in 292 of 536 participant

74 e without current comorbid overtly expressed irritability/anger.

75 ion, included reductions in the frequency of irritability, anxiety, and delusions; among patients who

76 ower total withdrawal symptom score and less irritability, anxiety, craving, and restlessness than pl

77 Genetic effects on irritability are developmentally dynamic from middle chi

78 fever, upper respiratory tract symptoms, and irritability are less useful.

79 lementary conceptualizations of pathological irritability are proposed: 1) aberrant emotional and beh

80 Youth irritability as reported by parents is a specific predic

81 l models, the phenotypic association between irritability at wave 2 and depression at wave 3 was acco

82 y cerebellar and cerebral atrophy, seizures, irritability, ataxia, and extreme spasticity.

83 ncy (beta -0.032, OR 1.10 [1.02-1.20]), more irritability (beta 0.032, OR 1.07 [1.01-1.14]), and more

84 Irritability (beta = 0.12, P = .03) and fear and/or anxi

85 y decreased locomotor activity and increased irritability but had no effect on sexual behavior, partn

86 eneity correlates with increased ventricular irritability by programmed electrical stimulation.

87 tate cancer is followed by bowel and bladder irritability, by increasingly severe sexual dysfunction

88 cally and pathophysiologically distinct, yet irritability can be a clinical feature of both illnesses

89 Behavioral measures included locomotion, irritability, copulation, partner preference, and aggres

90 Irritability correlated with amygdala activity across al

91 scent Development reported on the children's irritability, defined using a previously identified scal

92 01), including effects on withdrawal-related irritability, depression, and cannabis cravings.

93 sorder characterized by personality changes, irritability, depression, seizures, memory loss and some

94 ncluded dissociation and symptoms of "limbic irritability," depression, anxiety, and anger-hostility.

95 Youth irritability did not predict bipolar disorder or axis II

96 mine whether the neural mechanisms mediating irritability differ between bipolar disorder and DMDD, u

97 5% CI, 0.96-1.25] points; P = .02) and Anger/Irritability DRSP subscale score (1.22 [95% CI, 1.05-1.4

98 severe epilepsy including infantile spasms, irritability, failure to thrive, and stereotypic hand mo

99 = 9) presented in early infancy with severe irritability, followed by dystonia and stagnation of dev

100 growth restriction, infantile hypotonia, and irritability, followed by failure to thrive and short st

101 d environment was not a primary influence on irritability for males or females.

102 Irritability has been proposed to underlie the developme

103 xiety (hazard ratio=1.87, 95% CI=1.28-2.73), irritability (hazard ratio=1.84, 95% CI=1.31-2.58), and

104 Parents and physicians reported less irritability, improved alertness, or both in seven patie

105 If abused, such steroids can cause irritability, impulsive aggression, and signs of major d

106 with behavioural disorders characterized by irritability, impulsiveness, bizarre alterations in dres

107 baseline emotional and behavioral disorders, irritability in adolescence predicted major depressive d

108 Parent-reported irritability in adolescence was used to predict self-rep

109 Cross-sectionally, irritability in adolescence was widely associated with o

110 the potential usefulness of NAC for treating irritability in children with autistic disorder.

111 inhibition may contribute to impulsivity and irritability in children with bipolar disorder.

112 The role of irritability in developmental psychiatry, and in the pat

113 les, with new genetic risk factors affecting irritability in early and late adolescence for males.

114 ttle is known about the relationship between irritability in early life and its outcomes in mid-adult

115 to evaluate different approaches to treating irritability in the two disorders.

116 community samples indicate that nonepisodic irritability in youths is common and is associated with

117 dysfunction to improve treatment for severe irritability in youths.

118 As males age, genetic influences on irritability increase while nonshared environmental infl

119 eficiency have included depression, anxiety, irritability, insomnia, weakness, diminished libido, imp

120 Researchers disagree as to whether irritability is a diagnostic indicator for pediatric man

121 Irritability is a widely occurring DSM-IV symptom in you

122 Although irritability is among the most common reasons that child

123 Results indicate that while irritability is an important feature of severe mood dysr

124 Irritability is common in children and adolescents and i

125 his study examines the extent to which youth irritability is related to adult psychiatric outcomes by

126 ratio=0.40), anxiety (odds ratio=0.43), and irritability/lability (odds ratio=0.38).

127 he Aberrant Behavior Checklist subscales for irritability, lethargy/social withdrawal, and hyperactiv

128 itioned to produce migraine symptoms such as irritability, loss of appetite, fatigue, depression, or

129 rvasive antisocial character traits, such as irritability, manipulativeness, and lack of remorse.

130 ype bipolar disorder, the pathophysiology of irritability may differ among the groups and is influenc

131 essed mothers with high anxious distress and irritability may require medications that reduce these s

132 arly perimenopausal women had higher odds of irritability, nervousness, and frequent mood changes but

133 ALS is characterised by personality change, irritability, obsessions, poor insight, and pervasive de

134 utward currents could also contribute to the irritability of the central nervous system typical of cl

135 reased rates of behavior problems, including irritability, oppositional defiant behavior, conduct dis

136 Although symptoms of irritability or anger are not central to the diagnosis o

137 a extend prior work conducted in youths with irritability or anxiety alone and suggest that research

138 ining sleep, accompanied by symptoms such as irritability or fatigue during wakefulness.

139 ts, and more days in the preceding year with irritability or mood elevation.

140 ome characterized by episodic acute onset of irritability or neurological deficits between 2 months a

141 od regulation problems in the form of either irritability or short episodes of mania-like symptoms in

142 regulation problems, such as severe chronic irritability or short episodes of mania-like symptoms, a

143 esses may be effective for cases with severe irritability or short episodes of mania-like symptoms.

144 he evidence base for the treatment of either irritability or short-lived episodes of mania-like sympt

145 characteristic of asthma is increased airway irritability, or bronchial hyperresponsiveness (BHR) whi

146 ania is accompanied by symptoms of euphoria, irritability, or excitation, whereas depression is assoc

147 uch as mood stabilizers, which dampen limbic irritability, or selective serotonin reuptake inhibitors

148 T alone had no effect on locomotion, irritability, or sexual behavior but increased partner p

149 with a lower frequency of reported colic or irritability (P < 0.001) and a lower frequency of antibi

150 or nervousness (P<.02), depression (P<.03), irritability (P<.01), and the overall behavioral symptom

151 ion, depressed state, sleep disturbance, and irritability/paranoia.

152 Irritability, presumably secondary to pain or headache d

153 tional anisotropy were seen in patients with irritability relative to control subjects.

154 Aggression, anger, irritability, restlessness, and strange dreams increased

155 in outcome measures were the DRF symptoms of irritability, sadness, and anxiety.

156 reduction in several core PMDD symptoms (ie, irritability, sadness, anxiety, food cravings, and bloat

157 ned as at least a 25 percent decrease in the Irritability score and a rating of much improved or very

158 resulted in a 56.9 percent reduction in the Irritability score, as compared with a 14.1 percent decr

159 al and genetic findings suggest that chronic irritability should be regarded as a mood problem that i

160 Irritability showed a significantly stronger phenotypic

161 f frustration, children with severe, chronic irritability showed abnormally reduced activation in reg

162 terised by feelings of threat, restlessness, irritability, sleep disturbance, and tension, and sympto

163 degrees F, pericardial friction rub, patient irritability, small pericardial +/- pleural effusion.

164 search is needed to relate these findings to irritability specifically, rather than to other clinical

165 resulted in significant improvements on ABC irritability subscale (F = 6.80; p < .001; d = .96).

166 ry outcomes: the Aberrant Behavior Checklist-Irritability subscale (range, 0-45) and the Home Situati

167 der (age 18-45 years; full scale IQ >70; ABC-Irritability subscale 13).

168 At week 24, the Aberrant Behavior Checklist-Irritability subscale declined 47.7% in parent training

169 imary outcome measures were the score on the Irritability subscale of the Aberrant Behavior Checklist

170 l measure (Aberrant Behavior Checklist [ABC] irritability subscale) and safety measures were performe

171 om clusters (depressive, physical, and anger/irritability symptoms).

172 Mood and behavioural symptoms, including irritability, tension, depressed mood, tearfulness, and

173 , the authors present a mechanistic model of irritability that integrates clinical and translational

174 ache, sleep disturbance, inability to relax, irritability) that does not resolve by resting or relaxi

175 athology during their lifetime, varying from irritability to psychosis, but prevalences of particular

176 tern of genetic and environmental effects on irritability using data from a prospective, four-wave lo

177 ith high levels of anxiety but low levels of irritability (Wald chi21 = 21.3; P < .001 for contrast).

178 Irritability was associated with differences in neural r

179 premenstrual-related tiredness, sadness, and irritability were assessed twice over 6 years in 1,312 m

180 am, associations between neural activity and irritability were found more consistently in the DMDD gr

181 n, anger-hostility, dissociation and 'limbic irritability' were assessed by rating scales.

182 ociated with high levels of both anxiety and irritability, whereas increased connectivity was associa

183 Both link to discrete pathophysiology: irritability with disruptions in prefrontal regulation o

184 othesized that during face emotion labeling, irritability would be associated with dysfunctional acti