ライフサイエンスコーパス: irritants

1 airway defense against inhaled pathogens and irritants.

2 rs chronically exposed to moderate levels of irritants.

3 after chronic exposure to moderate levels of irritants.

4 ons or exposure to allergic and non-allergic irritants.

5 hagous fluids, environmental xenobiotics and irritants.

6 ent of TRPA1, a key sensor for environmental irritants.

7 matory responses to cutaneous and peritoneal irritants.

8 y airway exposures to allergens and chemical irritants.

9 ell as environmental and endogenous chemical irritants.

10 in increased penetrability to allergens and irritants.

11 pungent natural compounds and environmental irritants.

12 y for behavioral responses to these chemical irritants.

13 nd mediates behavioral responses to chemical irritants.

14 pungent natural compounds, and environmental irritants.

15 ion of nociceptors by endogenous and natural irritants.

16 mach less susceptible to damage from luminal irritants.

17 lvents, welding fumes, and other respiratory irritants.

18 xposure to allergens, pathogens, or chemical irritants.

19 hich respond to numerous odorants as well as irritants.

20 tinocytes treated with certain allergens and irritants.

21 es to protect the host against pathogens and irritants.

22 oxyethylene) ammonium chloride (ITDOP); mild irritants: 5% 3-decyloxypropyl-bis(polyoxyethylene) amin

23 Test materials included slight irritants: 5% sodium lauryl sulfate (SLS), polyoxyethyle

24 o enhance permeability and susceptibility to irritants; accordingly, increased attention should be gi

25 rritation response in mice elicited by smoke irritants (acrolein, acetic acid, and cyclohexanone).

26 ral, bacterial, and nonmicrobial (toxins and irritants) agents, resulting in production of many diffe

27 rosols with increasing doses of the chemical irritants allyl isothiocyanate (AITC; also known as must

28 nded chemical data set, comprising five skin irritants and 11 contact allergens.

29 s can affect airway inflammatory response to irritants and allergens, but the importance of stress in

30 r challenges, including allergens, exercise, irritants and aspirin.

31 uction machinery through which environmental irritants and endogenous proalgesic agents depolarize no

32 ormal breathing by a myriad of environmental irritants and infectious insults.

33 cautions should be taken against respiratory irritants and molds and to prevent children from becomin

34 acts as a sensory receptor for environmental irritants and oxidants.

35 tion following long-term exposure to harmful irritants and pollutants, particularly in the airways.

36 el is the molecular target for environmental irritants and pungent chemicals, such as cinnamaldehyde

37 hat they can be activated by various inhaled irritants and/or cold air.

38 condary ozonides (SOZ), which are known skin irritants, and a modest change in particle size.

39 PCR analyses of multiple chemical allergens, irritants, and non-sensitizers have identified 10 genes

40 multiple symptomatic high-level exposures to irritants; and (iii) possible IIA, that is asthma occurr

41 Receptors for trigeminal irritants are generally assumed to be located exclusivel

42 ctivated by noxious heat, acid, and alkaloid irritants as well as several endogenous ligands and is s

43 ons to aeroallergens, contact allergens, and irritants at days 2, 3, and 4.

44 side' world from potentially harmful toxins, irritants, bacteria and other pathogens that also exist

45 gions in the mouth are uniquely sensitive to irritants because they can penetrate through the tissue

46 s sensory detection of pathogens, toxins and irritants; breakdown of the epithelial barrier is associ

47 ubstances, toxins, venoms, and environmental irritants but that also trigger exuberant allergic react

48 Detection of such irritants by the trigeminal nerve evokes protective refl

49 Airway irritants cause a variety of lung pathologies.

50 rs after treatment, mild and moderate ocular irritants caused a significant increase in corneal thick

51 he epithelium, whereas the mild and moderate irritants caused complete epithelial cell loss with incr

52 On day 1, mild, moderate, and severe irritants caused complete loss of epithelium and disappe

53 nflammation via hapten-specific T cells) and irritants (chemicals that are toxic to epidermal cells).

54 tinocytes treated with certain allergens and irritants, compared with untreated keratinocytes.

55 and bulb may provide an avenue whereby nasal irritants could affect processing of coincident olfactor

56 nasal epithelium, requiring that trigeminal irritants diffuse through the junctional barrier at the

57 ave been identified, including environmental irritants (e.g., acrolein) and ingredients of pungent na

58 (e.g., allyl isothiocyanate), environmental irritants (e.g., acrolein), and endogenous ligands (4-hy

59 nerve endings can detect certain lipophilic irritants (e.g., mints, ammonia), the epithelium also ho

60 n excitatory ion channel targeted by pungent irritants from mustard and garlic.

61 s, microbial products and sterile endogenous irritants governs whether the outcome will be with suppr

62 Plant-derived irritants have predominated in this regard, but animal v

63 vironmental and occupational sensitizers and irritants in its pathogenesis and the interaction with b

64 exposed to a range of physical and chemical irritants in the environment that are known to trigger a

65 eurons and are activated by several chemical irritants in vitro.

66 igeminally mediated reflex reactions to some irritants including acyl-homoserine lactone bacterial qu

67 where it acts as a sensor for environmental irritants, including acrolein, and some pungent plant in

68 mediators and to a diverse array of volatile irritants, including those found in tear gas and garlic.

69 Control of environmental allergens and irritants is essential.

70 injury, information on possible etiology of irritants is very important.

71 ature of bronchial asthma, and inhalation of irritants may facilitate development of nonallergic AHR.

72 These data suggest that allergens and irritants may, in part, break peripheral tolerance by th

73 , but not prevented, by elimination of local irritants, meticulous oral hygiene, and regular periodon

74 ave examined in vivo and in vitro effects of irritants, most focused on events developing hours to da

75 itial management includes avoiding causative irritants or allergens (e.g., by wearing impermeable glo

76 s) may increase the risk of LRI by acting as irritants or through increasing susceptibility to infect

77 and clears the airways and lungs of inhaled irritants, particulates, pathogens, and accumulated secr

78 On day 1, mild and moderate irritants showed increasing stromal cell death from 9.8+

79 ess C5aRs and that exposure to environmental irritants such as cigarette smoke modulates the expressi

80 Various irritants such as foods, chemicals, friction, thermal/me

81 Oxidative stresses from irritants such as hydrogen peroxide and ozone (O(3)) can

82 s and responds to a wide variety of chemical irritants, such as acrolein in smoke or isothiocyanates

83 TRPA1 is also targeted by environmental irritants, such as acrolein, that account for toxic and

84 This contrasts with most other common oral irritants, such as cinnamaldehyde, capsaicin, and alcoho

85 rodentium but not to that caused by chemical irritants, such as dextran sodium sulfate.

86 Inhalation of irritants, such as toluene diisocyanate (TDI), stimulate

87 cle beginning on page 2574), have identified irritants that activate transient receptor potential cat

88 In response to infections and irritants, the respiratory epithelium releases the alarm

89 With the slight ocular irritants there was little or no change in corneal thick

90 can be activated by exogenous electrophilic irritants through direct covalent modification, we reaso

91 ized epithelial chemosensors that respond to irritants through the canonical taste transduction casca

92 vivo CM revealed corneal injury with slight irritants to be restricted to the epithelium, whereas th

93 Thus, in CF, the reduced ability of mucosal irritants to stimulate airway gland secretion via SubP m

94 , that is activated by a variety of reactive irritants via the covalent modification of cysteine resi

95 hannels are activated by chemically reactive irritants, whereas snake and Drosophila TRPA1 orthologs

96 single or multiple high-level exposure(s) to irritants, whereas this relationship can only be inferre