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1                                  Renal ischemia/reperfusion is a major cause of acute kidney injury.
2                                 Respiratory syncytial virus is a major cause of acute lower respiratory tract infection i
3                              Chronic cerebral hypoperfusion is a major cause of age-related vascular cognitive impairment
4                                        Campylobacter jejuni is a major cause of bacterial gastroenteritis worldwide, prim
5                                      Neisseria meningitidis is a major cause of bacterial meningitis and sepsis worldwide
6                                   Retinitis pigmentosa (RP) is a major cause of blindness that affects 1.5 million people
7 ogical angiogenesis.Pathological angiogenesis in the retina is a major cause of blindness.
8                               Human colorectal cancer (CRC) is a major cause of cancer mortality and frequently harbors a
9 obally diarrheal disease through contaminated water sources is a major cause of child mortality.
10                  RATIONALE: Lower respiratory tract illness is a major cause of childhood morbidity and mortality.
11                                      Traumatic brain injury is a major cause of death and disability, yet many predictors
12                                                  Metastasis is a major cause of death in patients with EOC, but the under
13                                       Prostate cancer (PCa) is a major cause of death since ancient time documented in Eg
14 by critical illness (intensive care unit acquired weakness) is a major cause of disability in patients and is currently u
15 ysis, is the most common hip abnormality in adolescents and is a major cause of early osteoarthritis.
16 c obstructive pulmonary disease (COPD) patients, this virus is a major cause of exacerbations resulting in an increased u
17                                  Multidrug resistance (MDR) is a major cause of failure in cancer chemotherapy.
18                          This condition, termed sarcopenia, is a major cause of falls and of the subsequent increase in m
19                  Inflammatory dilated cardiomyopathy (DCMi) is a major cause of heart failure in children and young adult
20 ease cardiomyopathy, caused by Trypanosoma cruzi infection, is a major cause of heart failure in Latin America.
21                                  Inadequate target exposure is a major cause of high attrition in drug discovery.
22 ysfunction of the oxidative phosphorylation (OXPHOS) system is a major cause of human disease and the cellular consequenc
23                             Talaromyces marneffei infection is a major cause of human immunodeficiency virus (HIV)-relate
24                              Gram-negative bacteremia (GNB) is a major cause of illness and death after hematopoietic ste
25                                                    Glaucoma is a major cause of irreversible blindness worldwide.
26                      Age-related macular degeneration (AMD) is a major cause of irreversible vision loss.
27                           Antibody-mediated rejection (AMR) is a major cause of kidney allograft loss.
28                           Hepatitis C virus (HCV) infection is a major cause of liver cirrhosis and hepatocellular carcin
29                    Chronic graft versus host disease (GVHD) is a major cause of morbidity and mortality after allogeneic
30                                    Portal hypertension (PH) is a major cause of morbidity and mortality in chronic liver
31                                             Lung immaturity is a major cause of morbidity and mortality in premature infa
32                    Human respiratory syncytial virus (hRSV) is a major cause of morbidity and mortality in the paediatric
33                                     Coronary artery disease is a major cause of morbidity and mortality worldwide, and is
34                                             Atherosclerosis is a major cause of mortality and morbidity, which is mainly
35  invasion and metastatic progression in prostate cancer and is a major cause of mortality and morbidity.
36                                                   Influenza is a major cause of mortality and morbidity.
37                                       West Nile virus (WNV) is a major cause of mosquito-borne illness in the United Stat
38                                          Multiple sclerosis is a major cause of neurological disability, which accrues pr
39                                               Liver disease is a major cause of non-AIDS-related deaths, and as a result
40 virus (HPV) is a common sexually transmitted infection that is a major cause of noncervical anogenital and oropharyngeal
41                                   Spontaneous preterm birth is a major cause of perinatal morbidity and mortality.
42                     Noncompressible torso hemorrhage (NCTH) is a major cause of potentially survivable trauma death.
43                                        Acute tubular damage is a major cause of renal failure, especially at the early ph
44                                                     Smoking is a major cause of respiratory conditions.
45           The opportunistic pathogen Pseudomonas aeruginosa is a major cause of sepsis in severely burned patients.
46                                      Pseudomonas aeruginosa is a major cause of severe infections that lead to bacteremia
47                                       Staphylococcus aureus is a major cause of skin and soft tissue infection.
48                                Ventricular tachycardia (VT) is a major cause of sudden cardiac death.
49                                                         HBV is a major cause of viral hepatitis, liver cirrhosis, and hep
50                      Age-related macular degeneration (AMD) is a major cause of visual impairment that affects the centra

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