ライフサイエンスコーパス: is known to activate

1 udies with activated T cell lines maintained in vitro, IL-2 is known to activate multiple signaling pathways that show co

2 Protein phosphatase 2A is known to activate SP-1 through dephosphorylation at its se

3 otein (RhoGAP) MgcRacGAP/CYK-4 and the kinesin MKLP1/ZEN-4, is known to activate ECT-2, but the underlying mechanism is n

4 Tyr 1226/7 is known to activate the Ras/Erk pathway; however, paclitaxel

5 o study peripheral antihyperalgesic properties because ACEA is known to activate TRPV1.

6 Arf6 activation efficiently disrupts cell-cell contacts and is known to activate Rac1 and Rab7.

7 It is in the family of G-protein-coupled receptors and is known to activate Ca(2+) signaling, although relatively li

8 Since aphidicolin is known to activate DNA damage response (DDR) pathways, effe

9 oxide by endothelial nitric-oxide synthase, which ascorbate is known to activate, and the subsequent generation cGMP by g

10 Because TGF-beta is known to activate the MAPK/ERK pathway through direct phos

11 SREBP-2, a transcription factor whose proteolytic cleavage is known to activate a variety of phospholipid metabolic gene

12 Maturation by proteolytic cleavage is known to activate the enzyme.

13 The Snf1 complex is known to activate the general stress transcription factors

14 Although CRF is known to activate two receptor subtypes, CRF1 and CRF2, at

15 Although EGFRvIII dimerization is known to activate EGFRvIII, the factors that drive EGFRvII

16 signaling molecule associated with cardiovascular disease, is known to activate extracellular signal regulated kinases 1

17 As E5 is known to activate PDGFR within the thin membranes of the G

18 Acute alcohol exposure is known to activate the hepatic autophagy response, whereas

19 Chronic nicotine exposure is known to activate nicotinic acetylcholine receptors (nAChR

20 MDM2-ALT1, the major splice variant generated, is known to activate the p53 pathway and impede full-length M

21 Hyperglycemia is known to activate protein kinase C (PKC), affecting the ex

22 Tumor hypoxia is known to activate angiogenesis, anaerobic glycolysis, inva

23 ve, its molecular target has remained elusive - although it is known to activate anti-oxidant pathways.

24 croRNA, namely miR-9, through the Ras/PI3K/AKT axis that it is known to activate.

25 LANA is known to activate ERK and limit the activity of another ki

26 associated with Set1) family of histone methyltransferases is known to activate transcription of Hox genes in other cont

27 mTORC1 is known to activate sterol regulatory element-binding protei

28 Oxidized low-density lipoprotein (oxLDL) is known to activate inflammatory responses in a variety of c

29 Tumor suppressor p53 is known to activate certain sets of genes while suppressing

30 Pemetrexed is known to activate PARPs, thereby accelerating NAD consumpt

31 Inhibition of prolyl hydroxylase (PHD) is known to activate the transcription factor hypoxia-inducib

32 Tyrosine phosphorylation is known to activate STAT6 in response to cytokine stimulatio

33 and leucine-rich repeat-containing (NLR) family of proteins is known to activate innate immunity, and the inflammasome-as

34 Reelin is known to activate signalling cascades regulating neuronal

35 RECENT FINDINGS: Smad-mediated transcription regulation is known to activate TGF-beta-induced EMT.

36 Starvation, or caloric restriction, is known to activate the transcription factor EB (TFEB), a ma

37 l level, oxidation of the cardiac ryanodine receptor (RyR2) is known to activate and inhibit the channel depending on the

38 In humans, touching the skin is known to activate, among others, the contralateral primary

39 SOX2 is known to activate expression of Six6, encoding a homeodoma

40 Since telomere dysfunction in other systems is known to activate ATM (ataxia telangiectasia mutated)-medi

41 The MUC1 cytoplasmic tail is known to activate multiple signaling pathways through its

42 ultisubunit-binding site for an S-phase protein kinase that is known to activate DNA replication.

43 Extracellular ATP is an endogenous danger signal that is known to activate inflammatory responses in innate immune

44 Oxidized thioredoxin is known to activate apoptosis signal-regulating kinase 1, an

45 Because TZD is known to activate AMP-activated protein kinase (AMPK), we

46 Uric acid (UA) is known to activate the NLRP3 (Nacht, leucine-rich repeat an

47 ncomitant activation of the rat sarcoma protein Kras, which is known to activate p110alpha, and loss of PTEN.

48 ent mitochondrial reactive oxygen species production, which is known to activate transient receptor potential ankyrin-1 o

49 control conditions and after 4 h of cold-stimulation, which is known to activate BAT.

50 nt expression of p53 or in response to folate stress, which is known to activate p53.