ライフサイエンスコーパス: is required for

1 esulting from multiple interdependent phosphorylation sites is required for a GC-A conformation capable of transmitting t

2 KL controls the expression of 3BP2, an adapter protein that is required for activation of SRC tyrosine kinase and simulta

3 BPTF is required for anterior-posterior axis formation of the mous

4 tective effect of aPC, demonstrating that Nlrp3 suppression is required for aPC-mediated protection from IRI.

5 The induction of SMARCA2 in response to EZH2 inhibition is required for apoptosis, but not for growth arrest, through

6 Coordination between osteoblasts and osteoclasts is required for bone health and homeostasis.

7 unit of the mammalian SWI/SNF chromatin-remodeling enzymes, is required for both myoblast proliferation and differentiati

8 PRC2 is required for chromatin reprogramming in the germline, and

9 namic induction of DLL4 transcription and that this pathway is required for DLL4 expression.

10 ific but necessarily weak binding of tropomyosin to F-actin is required for effective thin filament function.

11 s not essential for H3-H4 tetrasome deposition in vitro, it is required for efficient DNA synthesis-coupled nucleosome as

12 Together, these data demonstrate that H2A.Z is required for efficient pre-mRNA splicing and indicate a ro

13 Our results altogether suggest that MSRB8 function is required for ETI and containment of stress-induced cell de

14 out the need for collimated or polarised incident light, as is required for existing methods.

15 Thus, mTORC1 activation is required for fueling B cells prior to DZ proliferation rat

16 ata suggest that controlled but not constitutive activation is required for gonococcal infection in mice.

17 chores mature through Ska complex recruitment and that this is required for improved load-bearing capacity and silencing

18 ugh dispensable for homeostatic Th17 cell development, JunB is required for induction and maintenance of Th17 effector re

19 fic ablation of eIF2alphaP and demonstrated that eIF2alphaP is required for induction of ATF4 protein synthesis in vivo i

20 the endothelium, and Mac-1 engagement of platelet GPIbalpha is required for injury responses in diverse disease models.

21 lar protein known to remain at the base of mature cilia and is required for intraflagellar transport trafficking.

22 mentation test results suggest that phosphorylation of EMS1 is required for its function in anther development.

23 Mechanistically, CD2AP is required for mechanosensitive ICAM-1 downstream signaling

24 for embryonic development, while maternally deposited gdf3 is required for mesendoderm formation and dorsal-ventral patt

25 We show that condensin II function at the centromere is required for new CENP-A deposition in human cells.

26 Qa, immediately upstream of the SNARE heptad-repeat domain, is required for normal fusion activity with HOPS.

27 One such nuclear receptor is DAF-12, which is required for normal nematode development, including the al

28 Together, our data suggested that protein O-mannosylation is required for normal sensory feedback to control coordinate

29 Finally, we found that ST8Sia-IV autopolysialylation is required for NRP-2 polysialylation and that ST8Sia-II auto

30 Here we show that the INO80 chromatin remodeling complex is required for oncogenic transcription and tumor growth in n

31 activity of SWR, whereas an acidic region at the N-terminus is required for optimal SWR function.

32 coactivator with PDZ-binding motif (TAZ) expression, which is required for osteoblast proliferation and differentiation

33 First, after DSB formation, Mer2 is required for pairing by mediating homolog spatial juxtapos

34 Thus, we sought to determine if intrinsic MAVS signaling is required for participation of Tregs in anti-WNV immunity.

35 We show that signalling through the TrpA1 thermo-sensor is required for PMW, and that TrpA1 specifically impacts sies

36 Furthermore, RYBP is required for PRC1-independent recruitment of OCT4 to the p

37 al recordings show that Sema-1a-dependent R axon lamination is required for preventing the spread of synaptic inhibition

38 d DNA is determined by its ATPase domain, that this binding is required for processing protein substrates in nucleoprotei

39 Here, we demonstrated that T-cell intrinsic MyD88 signaling is required for proliferation, protection from apoptosis and

40 a C2B surface implicated in SNARE complex interaction that is required for rapid synchronization and Ca(2+) cooperativit

41 Functionally, Tet3 is required for robust axon regeneration of DRG neurons and b

42 omal protein uS10 by the E3 ubiquitin ligase Hel2 (or RQT1) is required for RQC.

43 Here, we show that IRF8 is required for Th9 differentiation in vitro and in vivo.

44 Copper is required for the activity of cytochrome c oxidase (COX), t

45 Ls is an integral component of axon-glial communication and is required for the function and maturation of OLs to promote

46 This is required for the induction of lipophagy, but not basal aut

47 plexes transport nuclear-encoded proteins, whereas the Oxa1 is required for the insertion of mitochondria-encoded membran

48 Only a reduced electronics with very low power consumption is required for the reading of the optical responses and data

49 We also found that the extracellular domain of IL1RAPL1 is required for this effect, independently of the interaction

50 Positive transmural pressure is required for this suction, providing the energy required t