ライフサイエンスコーパス: is the

1 Tailor-made: Discussed herein is the ability to adapt biology's mechanisms for innovation a

2 Wettability is the affinity of a liquid for a solid surface.

3 A particularly promising target is the bacterial two-component system.

4 A major factor in the variation of SUMO-target function is the balance between the conjugated/de-conjugated forms.

5 e underlying mechanism of this intriguing gas-like adhesion is the configurational entropy difference between the freesta

6 The key signal amplification reaction for the checkpoint is the conformational conversion of "open" mitotic arrest def

7 any gastrointestinal and hepatic diseases for which obesity is the direct cause (eg, nonalcoholic fatty liver disease) or

8 Human T-cell leukemia virus type 1 (HTLV-1) is the etiological agent of adult T-cell leukemia (ATL) and H

9 This is the first bivariate GWAS meta-analysis to demonstrate gene

10 To our knowledge, this study is the first demonstration of an integrated approach to eluci

11 The approach, which is the first demonstration of applicability of molecular dock

12 This study is the first demonstration that an SRRP is required to bind b

13 Phenylalanine ammonia-lyase (PAL) is the first enzyme of the general phenylpropanoid pathway ca

14 The mucous barrier of our digestive tract is the first line of defense against pathogens and damage.

15 This is the first report describing the ability of the pH1N1 NS1 p

16 To our knowledge, this is the first report of nucleolar functions for NSs within the

17 ly developed method that utilizes this type of acceleration is the five-dimensional echo planar J-resolved spectroscopic

18 st quantify the heritability of set-point viral load, which is the fraction of variation in this phenotype attributable t

19 Strengthening by precipitation of second phase is the guiding principle for the development of a host of hig

20 An ongoing challenge is the identification of biomarkers that predict which patien

21 Profiling the expression patterns of snoRNAs is the initial step in determining their functional significa

22 The autoimmune regulator (AIRE) protein is the key factor in thymic negative selection of autoreactiv

23 One potential explanation is the lack of capacity of this agent to penetrate the centra

24 INTERPRETATION: To our knowledge, this is the largest randomised controlled trial of a psychological

25 Glaucoma is the leading cause of irreversible blindness worldwide.

26 a cell monolayer essential for photoreceptor survival, and is the leading cause of vision loss in the elderly.

27 bisphosphate (PI(3,4)P2), suggesting that the macropinosome is the location where Rab8a is active.

28 Myo-inositol hexakisphosphate (IP6), is the main iron chelator in cereals and bread.

29 Our results indicate that, although phase separation is the main mode of recruitment for four of the studied prote

30 Common to all target nuclei investigated here is the maintenance of projection topology from different barr

31 Enterovirus A71 (EV-A71) is the major cause of severe hand, foot, and mouth disease an

32 We found that SRS is the major predictor of transcriptomic variation; a small n

33 Central to this problem is the mechanism by which a brain region adjusts its activity

34 A defining hallmark of primary and metastatic cancers is the migration and invasion of malignant cells.

35 Misophrioida (=Propodoplea Lang, 1948) is the most basal Podoplean order.

36 Atrial fibrillation (AF) is the most common cardiac arrhythmia and is associated with

37 African tick bite fever is the most commonly encountered travel-associated rickettsio

38 Using the lab strain NL4-3, we found that A5 (env/nef) is the most commonly used acceptor (about 50%) and A3 (tat) t

39 st electron donating functional group (p-(CH3CH2)2NPh-MoS2) is the most efficient catalyst for HER in this series, with i

40 ifficulty of females finding mates as male density declines is the most frequently reported mechanism of Allee effects in

41 The high-mobility group box transcription factor SOX4 is the most highly expressed SOX family protein in pancreatic

42 ceived barrier, especially for pediatric oncology patients, is the notion that patients and their families may not need o

43 BiP is the only Hsp70 chaperone in the endoplasmic reticulum (ER)

44 One of the key findings of our study is the overall shift toward excitation in liver-related hypot

45 A common and serious problem with this therapy is the patient's immune response to FVIII, because of a lack

46 The underlying basis of thalassemia pathology is the premature apoptotic destruction of erythroblasts causi

47 ciliary clearance, driven by the engine of ciliary beating, is the primary physical airway defense against inhaled pathog

48 The mucosal layer of conducting airways is the primary tissue exposed to inhaled microorganisms, alle

49 Central to CD8(+) T cell-mediated immunity is the recognition of peptide-major histocompatibility comple

50 Cytochrome P450 reductase (CPR) is the redox partner for most human cytochrome P450 enzymes.