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1 everal azoles but higher susceptibilities to isavuconazole.
2                          Patients were given isavuconazole 200 mg (as its intravenous or oral water-s
3  1 mug/ml), posaconazole (0.5 and 1 mug/ml), isavuconazole (4 and 4 mug/ml), and amphotericin B (0.25
4 o day 42 for the ITT population was 19% with isavuconazole (48 patients) and 20% with voriconazole (5
5                            The activities of isavuconazole against the larger collection of Candida s
6          We report the MIC distributions for isavuconazole and 111 isolates of Candida (42 Candida al
7 ere reported in 109 (42%) patients receiving isavuconazole and 155 (60%) receiving voriconazole (p<0.
8           Most patients (247 [96%] receiving isavuconazole and 255 [98%] receiving voriconazole) had
9              Mucormycosis cases treated with isavuconazole as primary treatment were matched with con
10                                              Isavuconazole can be used for treatment of mucormycosis
11 ality in seven (33%) of 21 primary-treatment isavuconazole cases was similar to 13 (39%) of 33 amphot
12                                              Isavuconazole demonstrates broad-spectrum activity again
13 2013, 37 patients with mucormycosis received isavuconazole for a median of 84 days (IQR 19-179, range
14 mphotericin, he was treated effectively with isavuconazole for over 6 months despite ongoing treatmen
15               Our results support the use of isavuconazole for the primary treatment of patients with
16       We assessed the efficacy and safety of isavuconazole for treatment of mucormycosis and compared
17 ulfate 372 mg (prodrug; equivalent to 200 mg isavuconazole; intravenously three times a day on days 1
18                                              Isavuconazole is a new broad-spectrum triazole with a fa
19                                              Isavuconazole is a new extended-spectrum triazole with a
20                                              Isavuconazole is a novel triazole with broad-spectrum an
21                                              Isavuconazole is a triazole active in vitro and in anima
22                                              Isavuconazole is an extended-spectrum triazole with in v
23                                              Isavuconazole (ISAV) is a novel, broad-spectrum, triazol
24             Also, the relative activities of isavuconazole, itraconazole, fluconazole, posaconazole,
25                                              Isavuconazole MIC values for three mucormycete isolates
26 e study included 158 patients overall and 78 isavuconazole patients in the PK/PD modeling.
27 acodynamic (PK/PD) analysis in patients with isavuconazole plasma concentrations was conducted to est
28 azole and voriconazole; the MIC90 values for isavuconazole, posaconazole, and voriconazole against Ca
29                                              Isavuconazole showed activity against mucormycosis with
30                                              Isavuconazole showed good activities against Cryptococcu
31 f invasive mucormycosis showed efficacy with isavuconazole that was similar to that reported for amph
32 ed to result in a negative GMI at the end of isavuconazole therapy.
33                                     However, isavuconazole-treated patients had a lower frequency of
34 SECURE trial assessed efficacy and safety of isavuconazole versus voriconazole in patients with invas
35                                              Isavuconazole was non-inferior to voriconazole for the p
36 ive aspergillosis found that the efficacy of isavuconazole was noninferior to that of voriconazole.
37                                              Isavuconazole was well tolerated compared with voriconaz
38 se studies, as well as in normal volunteers, isavuconazole was well tolerated, appeared to have few s

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