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1 avones, 2 flavonols, 2 phenylethanoids and 1 isoflavone).
2 Daidzein (1) is a natural estrogenic isoflavone.
3 o anticancer effects of genistein, a soybean isoflavone.
4 urce of macronutrients and phytochemicals as isoflavones.
5 cium, vitamin D, protein, potassium, and soy isoflavones.
6 ly because they are uniquely rich sources of isoflavones.
7 perature hardly affected the total amount of isoflavones.
8 ols and flavonols with soybean having mainly isoflavones.
9 entified as one of the up-regulated genes by isoflavones.
10 were screened as putative sources of dietary isoflavones.
11 ure of 30 degrees C was deleterious to grape isoflavones.
12 nd influences of dietary components, such as isoflavones.
13 plement based on soy germ containing 55.24mg isoflavones.
14 h, contain high levels of plant estrogens or isoflavones.
15 2DM treated with soy, either with or without isoflavones.
16 were tested while assaying soy glycosilated isoflavones.
17 as evaluated as potential tool to purify soy isoflavones.
18 ed the extractability of total phenolics and isoflavones.
19 thodology to extract, concentrate and purify isoflavones.
20 roved in EPs at 24 h (cfPWV change from 0 h: isoflavone, -0.2 +/- 0.2 m/s; placebo, 0.6 +/- 0.2 m/s;
21 3.48 ppb [95% CI, -5.99 to -0.97 ppb] vs soy isoflavones, 1.39 ppb [95% CI, -1.73 to 4.51 ppb]) did n
22 ither high-normal (73 mg/d) or low (10 mg/d) isoflavones, 2) soy foods with or without a prebiotic to
23 st (placebo, 1.98 [95% CI, 1.42-2.54] vs soy isoflavones, 2.20 [95% CI, 1.53-2.87]; positive values i
24 ntrol (placebo, 3.3 [95% CI, 2.7-4.1] vs soy isoflavones, 3.0 [95% CI, 2.4-3.7]), and changes in exha
25 the sum of individuals and 20% by F-C assay; isoflavones 36% and constituents with antioxidant activi
26 of soy isoflavone capsules (80 mg/d of total isoflavones, 51 mg/d aglucon units) on serum and tissue
27 reviously unreported compounds including two isoflavones 7,5'-dihydroxy-6,3'-dimethoxy-isoflavone-7-O
28 noside (4) and 7,5'-dihydroxy-6,3'-dimethoxy-isoflavone-7-O-(7,8-dihydro-p-hydroxycinnamoyl)-bet a-d-
29 wo isoflavones 7,5'-dihydroxy-6,3'-dimethoxy-isoflavone-7-O-beta-d-glucopyranoside (4) and 7,5'-dihyd
31 excretion of glycitein compared to other soy isoflavones after a unique intake of food supplement bas
32 protein (18 g) + isoflavone tablets (105 mg isoflavone aglycone equivalents), soy protein + placebo
33 mg flavan-3-ols (90 mg epicatechin) + 100 mg isoflavones (aglycone equivalents)/d] or matched placebo
34 ection for the simultaneous determination of isoflavone aglycones (daidzein, glycitein and genistein)
35 sed a novel red clover extract (RCE) rich in isoflavone aglycones and probiotics to concomitantly pro
37 Maximum conversion of beta-glucosides into isoflavone aglycones involved soaking the soybeans at 5
40 alcitriol (25 mug/d) given either RCE (60 mg isoflavone aglycones/d and probiotics) or a masked place
41 olecules (glucose, sucrose, and pinitol) and isoflavone aglycons were increased but the isoflavones g
42 r the protective effect of soy is due to soy isoflavones alone or to their combination with other ben
44 ntribution of dietary food groups to urinary isoflavone and daidzein metabolite concentrations in a r
45 he objective was to examine whether combined isoflavone and flavan-3-ol intake alters vascular functi
47 ine the beneficial effects of a bioavailable isoflavone and probiotic treatment against postmenopausa
50 rations of glycosylated, malonyl, and acetyl isoflavones and a corresponding increase in the concentr
51 evaluate changes in the phenolic compounds, isoflavones and antioxidant activity of soymilk followin
54 rmented soymilk is a good source of aglycone isoflavones and phenolics, since the content of these su
56 ability, the potential biological effects of isoflavones and soyasaponins in infants should not be ov
57 e present study we determine the contents of isoflavones and soyasaponins in seven soy-based infant f
59 f the contents of different forms of soybean isoflavones and the effect of germination time on these
60 ole soybean flour (WSF) on the conversion of isoflavones and the inactivation of trypsin inhibitors.
65 soybeans had significantly higher TPC, total isoflavones, and peroxyl, hydroxyl, and ABTS(+) radical
72 such as anthocyanins, proanthocyanidins, and isoflavones, are stored in the central vacuole, but the
74 e and femoral neck for all studies providing isoflavones as aglycones.Twenty-six RCTs (n = 2652) were
75 pidemiological studies implicate dietary soy isoflavones as breast cancer preventives, especially due
76 he lentil samples with a standard mixture of isoflavones at three levels of fortification (5, 25 and
77 nd does not prenylate flavanone, flavone, or isoflavone backbones, even though it shares several comm
79 marily animal protein and one containing soy isoflavones before and after menopause may result in com
83 he metabolites of daidzein, a well known soy isoflavone, but its chemopreventive activity and the und
87 ontrolled trial to examine the effect of soy isoflavone capsules (80 mg/d of total isoflavones, 51 mg
89 tive of this study is thus to identify a soy isoflavone combination with lower levels of daidzein and
91 anipulation of beta-glycosidase activity and isoflavone composition can be used to modulate aglycone
92 (SIM) or almonds, and examined the impact of isoflavone composition in mediating conversion to aglyco
94 ase reporter assay, we identified a class of isoflavone compounds that act as specific agonists of in
95 a new analytical method for determining five isoflavone compounds, three of which are aglycons, namel
99 erences in soy isoflavone intake by country, isoflavone consumption was inversely associated with rec
100 14% by Folin-Ciocalteu [F-C] method), total isoflavone content (22%) and total antioxidant activity
102 s, which is possibly related to the specific isoflavone content or the variable equol-producing capac
105 central Italy and pulses for determining the isoflavone content, which was found to range from 1.1 to
106 tisus scoparius possessing the highest total isoflavones content (396 and 273 mg kg(-1), respectively
107 the effects of cooking and digestion on the isoflavone contents and bioactivities of the whole soy e
108 joint optimisation of the total phenolic and isoflavone contents as well as antioxidant activities: 0
110 process parameters in obtaining the WSF with isoflavone conversions and reductions in trypsin inhibit
115 e soy intervention delivered 105.23 mg total isoflavones/d as genistein, daidzein, and glycitein in t
116 ventions that ranged from 52 to 220 mg total isoflavones/d increased bone calcium retention between 3
117 the pooled analysis, consumption of >/=10 mg isoflavones/d was associated with a nonsignificant reduc
118 stdiagnosis soy food consumption of >/=10 mg isoflavones/d was associated with a nonsignificant reduc
119 reported that equol, a metabolite of the soy isoflavone daidzein, may advance breast cancer potential
120 equol, a microbial-derived metabolite of the isoflavone daidzein, which is produced in the large inte
122 very, we discovered that an FDA-approved soy isoflavone, daidzein, improved stroke-induced behavioral
123 constant (K), time (tau(50)) in which 50% of isoflavone deglycosylation was reached, and time (tau(co
124 (tau(complete)) required to achieve complete isoflavone deglycosylation, were 0.16+/-0.02 min(-1), 4.
125 on of the malonyls-glucosides and glucosides isoflavone derivatives into glucosides or aglycons forms
126 e data suggest that short-term intake of soy isoflavones did not affect serum hormone levels, total c
128 rmine whether the acute vascular benefits of isoflavones differ according to EP phenotype and subsequ
130 or 25 degrees C) to maximise the content of isoflavones, especially of high affinity for ERbeta.
131 in vitro and in vivo studies have shown that isoflavones exhibit anti-proliferative activity against
133 olled intervention with a genistein-rich soy isoflavone extract (10mg/kg/day of genistein) followed b
134 samples obtained from cows that received the isoflavone extract-supplemented diet than from those tha
135 ture, contact time and solid liquid ratio on isoflavone extraction from soybean flour or Soybean Prot
136 s no significant difference (p>0.05) between isoflavone extraction in water and in 70% aqueous ethano
138 ne (total aglycone/total isoflavones) in SIM isoflavone extracts increased significantly in raw (35%)
140 organic acids, and sugars) and 10 secondary (isoflavones, fatty acid methyl esters) metabolites.
141 s of phytochemicals, such as phenolic acids, isoflavones, flavones, flavonols and glucosinolates were
142 s were taken to be the contents of different isoflavone forms and the residual activity of trypsin in
143 During storage, there was a conversion of isoflavone forms to aglycones, being higher in heat-proc
145 een' extraction solvent for the isolation of isoflavones from okara, a by-product of soymilk producti
147 little is known about the bioavailability of isoflavones from whole soy food and their bioactivities
148 containing recombinant LaPT1 prenylated the isoflavone genistein at the B-ring 3' position to produc
152 trated that dietary daidzein or combined soy isoflavones (genistein, daidzein, and glycitein) increas
155 d isoflavone aglycons were increased but the isoflavones glucoside content decreased in the greenhous
156 nation of several classes of phytochemicals (isoflavones, glucosinolates, flavones, flavonols and phe
158 o spent coffee grounds for the conversion of isoflavone glycosides into their aglycones in black soym
159 s with formulations comprising predominantly isoflavone glycosides were included.Isoflavone treatment
161 0.01 L (95% CI, -0.07 to 0.07 L) in the soy isoflavone group, which were not significantly different
162 nsisted of a placebo control group and 2 soy isoflavone groups (80 compared with 120 mg/d); women rec
163 ntation for 2 y with 80-120 mg soy hypocotyl isoflavones has minimal risk in healthy menopausal women
170 d to determine the effects of the content of isoflavones in a soy supplement and the equol-producing
174 ents for gaining insight into the effects of isoflavones in humans, especially with regard to the eff
175 wn to the safety of using high levels of soy isoflavones in humans, which is especially the concern f
176 method allowed reliable determinations of 12 isoflavones in less than 8 min of chromatographic elutio
177 Although some recent studies have detected isoflavones in natural waters, little is known about the
178 lular senescence signaling by SPI-associated isoflavones in osteoblastic cells may explain the persis
180 s of their equol-producing status, and mixed isoflavones in their natural ratios are more effective t
181 was a significantly higher extractability of isoflavones in UHT (about 38%) than in UHPH-treated samp
182 ein-rich soy supplement and 3 doses of mixed isoflavones in various proportions) and a bisphosphonate
184 percentage of aglycone (total aglycone/total isoflavones) in SIM isoflavone extracts increased signif
185 attributed to high soy diets, and major soy isoflavones, in particular daidzein and genistein, are t
189 nderlying the SPI-protective effects involve isoflavone-induced normalization of insulin signaling in
195 thy participants, short-term flavan-3-ol and isoflavone intakes improve vascular function; however, t
201 evious study indicated that soy protein with isoflavones lessened lumbar spine bone loss in midlife w
202 e data suggest that supplementation with soy isoflavone may be an effective treatment for patients wi
204 ough selective estrogen receptor modulation, isoflavones may exert beneficial effects against estroge
210 lavone supplement containing 100 mg of total isoflavones (n=193) or matching placebo (n=193) in 2 div
211 ty-six men were randomized to treatment with isoflavones (n=42) or placebo (n=44) for up to six weeks
212 arameters and contents of different forms of isoflavones of the seeds and soybean sprouts were evalua
215 pression did not affect the actions of E2 or isoflavones on p53 expression in either ST2 or OB6 cells
216 ce and the other with soy protein containing isoflavones, on protein markers of hippocampal bioenerge
217 gue, Czech Republic), containing 40% soybean isoflavones, on the contents of daidzein, glycitein, gen
218 ther stimulation of estrogenic signaling via isoflavones or through a novel and as yet uncharacterize
220 ily supplementation with 80 mg soy hypocotyl isoflavones over a 6-wk period had no effect on nitric o
223 e of this study was to determine whether soy isoflavone phase II metabolism differs between humans an
225 or 120 mg aglycone equivalent soy hypocotyl isoflavones plus calcium and vitamin D on the health of
230 either heat nor UHPH treatments affected the isoflavone profile, as the percentage of each chemical f
232 perature treatment altered phenolic acid and isoflavone profiles; however, total isoflavones were una
235 king soy-juice for 15 or 60min decreases the isoflavone:protein ratios in Tofu from 6.90 to 3.57 and
239 (rDau c 1.0104; rDau c 1.0201; rDau c 4; the isoflavone reductase-like proteins rDau c IFR 1, rDau c
245 ed with 15 g soy protein containing 66 mg of isoflavones (SPI) or 15 g soy protein alone without isof
246 ipants were randomly assigned to receive soy isoflavone supplement containing 100 mg of total isoflav
248 d different soy foods, pure genistein, or an isoflavone supplement was <1% in steady state and <2% at
249 taking a controller medication, use of a soy isoflavone supplement, compared with placebo, did not re
251 d after control for pretreatment values, soy isoflavone supplementation had no effect on arginine flu
252 luate the clinical outcomes of soy hypocotyl isoflavone supplementation in healthy menopausal women a
253 The objective was to test the effect of soy isoflavone supplementation on nitric oxide production an
256 spite numerous clinical trials of short-term isoflavone supplementation, there is a paucity of data r
260 flavones have led some to view soy foods and isoflavone supplements as alternatives to conventional h
261 ffects of an 8-wk consumption of 2 different isoflavone supplements compared with placebo on whole-ge
262 aised concern that soy foods, and especially isoflavone supplements, are contraindicated for patients
264 nthesis was silenced via RNA interference of isoflavone synthase in soybean hairy root composite plan
265 4 intervention groups: soy protein (18 g) + isoflavone tablets (105 mg isoflavone aglycone equivalen
266 protein + placebo tablets, control protein + isoflavone tablets, and control protein + placebo tablet
269 atio of 20 to 1 and 20 degrees C, 47% of the isoflavones that can be extracted with 70% aqueous ethan
270 ystematic review and meta-analysis examining isoflavone therapies and bone mineral density (BMD) loss
271 ndomized controlled trials (RCTs) evaluating isoflavone therapies for treating BMD loss at the lumbar
272 was to optimise conversion of beta-glucoside isoflavones to aglycones in soymilk processing and to ev
275 stein, glycetin, secoisolariciresinol, total isoflavones, total lignans, and total phytoestrogens wer
276 estradiol, PSA, and total cholesterol in the isoflavone-treated group compared to men receiving place
277 For the femoral neck (18 RCTs, n = 1604), isoflavone treatment showed a significantly (P < 0.01) h
280 minantly isoflavone glycosides were included.Isoflavone treatments exert a moderately beneficial effe
281 c acids, 5 flavones, 4 phenylethanoids and 1 isoflavone; V. polita: 10 flavones, 5 phenolic acids, 2
282 c acids, 2 phenylethanoids, 1 flavonol and 1 isoflavone; V. spuria: 10 phenolic acids, 5 flavones, 2
285 entions such as dietary and supplemental soy isoflavones were associated with improvement in daily ho
290 oratory and animal studies reported that soy isoflavones were major bioactive compounds in soy to exe
295 ral products 3,3'-diinodolylmethane (DIM) or isoflavone, which increased miR-146a expression, caused
299 g increase in the concentrations of aglycone isoflavones, with the magnitude of these changes increas
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