ライフサイエンスコーパス: isoform

1 ends on the activity of the cytosolic GLXI;3 isoform.

2 pplied to any SUMOylation substrate and SUMO isoform.

3 ed as the ubiquitously-expressed shorter M87 isoform.

4 model systems expressing only a single VEGF isoform.

5 prion protein (PrP(C)) into the pathological isoform.

6 e contingent on cell context and the protein isoform.

7 hibiting expression of the coding NDC80 mRNA isoform.

8 tively switching the predominantly expressed isoforms.

9 ce, while retaining expression of Tcf1 short isoforms.

10 nnot be distinguished from bona fide protein isoforms.

11 ting a difference in the regulation of these isoforms.

12 l properties of three most important Amb a 1 isoforms.

13 duct) and antiangiogenic VEGFxxxb (VEGF165b) isoforms.

14 els of selectivity over other sodium channel isoforms.

15 ading to the production of alternative AIPL1 isoforms.

16 tivities after production of the recombinant isoforms.

17 a4)3(beta2)2 but not (alpha4)2(beta2)3 nAChR isoforms.

18 controls the functional diversity of protein isoforms.

19 ing between three-repeat and four-repeat Tau isoforms.

20 regulation and function of the various IL-32 isoforms.

21 initiation factors, eIF4E and eIF4G or their isoforms.

22 lant SS and bacterial glycogen synthase (GS) isoforms.

23 displayed augmented APOL1 toxicity with all isoforms.

24 ferredoxin and ferredoxin-NADP(+) reductase isoforms.

25 thereby concentrating and extracting all the isoforms.

26 to functional differences in diverse kinesin isoforms.

27 r RNA, leading to different regulation among isoforms.

28 nthesis of full-length and truncated SELENOP isoforms.

29 roducing distinct GRE-specific GRIP1 phospho-isoforms.

30 8, making CYP2C8 distinct from the other CYP isoforms.

31 translational capacity and quality of novel isoforms.

32 sulting in the overproduction of toxic Abeta isoforms.

33 opes present in the vast majority of Bet v 1 isoforms.

34 may be due to functional differences between isoforms.

35 characterized by accumulation of all six tau isoforms.

36 etics, morphology, and toxicity of all Abeta isoforms.

37 alaemia-induced two pore-domain K(+) channel isoform 1 (K2P1) leak cation currents, reconstituting tw

38 at inward rectifier K(+) channel subfamily 2 isoform 1 (Kir2.1) currents non-linearly counterbalance

39 isoform 2 overexpressing cells compared with isoform 1 overexpressing cells.

40 (PCDH11Y) and neuroligin 4 Y-linked (NLGN4Y; isoforms 1 and 2)-were developed.

41 shRNA-mediated knockdown of isoform 2 in BRAFi resistant cells restored sensitivity

42 Ube3a isoform 2 is conserved between mouse and human and known

43 nositol-3-kinase (PI3K) pathway signaling in isoform 2 overexpressing cells compared with isoform 1 o

44 ater phosphorylation of Na(+)/H(+) exchanger isoform 3 (NHE3), distribution of NHE3 at the base of th

45 CD47 isoforms 3 and 4 are expressed in all cell types tested

46 he Arabidopsis plasma membrane Ca(2+)-ATPase isoform 8 (ACA8) and that this interaction stimulates AC

47 Although three major Foxp1 isoforms (A, C, and D) are expressed in the brain, only

48 , C, and D) are expressed in the brain, only isoform-A has been studied in the nervous system.

49 nregulation of Foxp1 Elevating expression of isoform-A or -D protects cortical neurons from death cau

50 For Flt1, just three mRNA isoforms account for > 94% of all transcripts, with incr

51 Individuals expressing more protective isoform accumulate less brain beta-amyloid and have a lo

52 cific nucleotide-binding properties of MYO1C isoforms, adding to their kinetic diversity.

53 transcriptional programs controlled by these isoforms affect cancer progression and outcomes.

54 resolve endogenous signaling transducers and isoforms along vascular endothelial growth factor (VEGF)

55 s engineered to express three different LGR5 isoforms along with unique fluorescent protein lineage r

56 Compared to Amb a 1.02 or 03 isoforms, Amb a 1.01 showed higher IgE-binding activity.

57 ional roles for dysbindin-1A vs dysbindin-1C isoforms among phenotypes relevant to the pathobiology o

58 rement for both the interaction between NDPK isoforms and between NDPK isoforms and G proteins.

59 y the C-terminal domain (CTD) of the topo II isoforms and by a conserved non-catalytic tyrosine, Y640

60 ng full-length reads with those of annotated isoforms and explore the translational capacity and qual

61 ction between NDPK isoforms and between NDPK isoforms and G proteins.

62 ge investigation of the neurobiology of NRG3 isoforms and highlight inhibition of NRG3 signaling as a

63 ts HIV-1 infectivity, whereas the other Ser5 isoforms and mutants that do not have the 10th transmemb

64 Both the presence of several isoforms and the ability of the various domains and isof

65 exchanger in the heart and vasculature (NHE1 isoform) and the kidneys (NHE3 isoform) may serve as a c

66 These different isoforms are able to nucleate or frustrate the assembly

67 ing dominant-negative regulators, Tcf1 short isoforms are adequate in supporting developing thymocyte

68 lular EGTA, suggesting that the Cav1.3 short isoforms are closely associated with the release site at

69 unclear to what extent different NaV channel isoforms are distributed along the peripheral and centra

70 report that Actalpha, Actbeta, and Actgamma isoforms are expressed in primary mouse motoneurons and

71 results also suggest that GPD2 and GPD3 GPDH isoforms are important for nutrient starvation-induced T

72 the immunological characteristics of Amb a 1 isoforms are not fully investigated.

73 ez-Mockus et al. report that a subset of Sdt isoforms are targeted by the ubiquitin ligase Neuralized

74 imbalance of ASE and non-uniformity of gene isoform ASE is widespread, including tumorigenesis relev

75 We found that the isoform associates with metalloprotease-containing exoso

76 ow that we can identify and quantify complex isoforms at the single cell level.

77 Using electrophysiology, we show that one isoform, AtMCU1, gives rise to a Ca(2+)-permeable channe

78 We compare the dynamics of novel isoforms based on the number of supporting full-length r

79 ntly correlated, while the expression of the isoform BAX-beta, exclusively transcribed in apoptotic c

80 ers-BRD2, BRD3, BRD4 and the testis-specific isoform BRDT-that largely function as transcriptional co

81 eurotoxic effects of PrP(Sc), the infectious isoform, but how this occurs is mysterious.

82 gent C terminus shares the CBD common to all isoforms, but lacks the AID.

83 raction domain) peptide stabilized both beta isoforms by approximately 6-8 degrees C.

84 simultaneous quantification of abrin and its isoforms by mass spectrometry.

85 from which several predicted GLXI and GLXII isoforms can be derived through alternative splicing.

86 est how switching between different harmonin isoforms can regulate the formation of networks with Myo

87 Furthermore, AOX isoforms cannot be transformed to mimic one another by s

88 Thus, expression of a 5' extended mRNA isoform causes transcriptional interference at the downs

89 Here we report that the isoform characterized by the presence of extradomain A a

90 ce with rank order of potencies among GABAAR isoforms consistent with results from voltage-clamp expe

91 Moreover, specific APP isoforms contain Kunitz protease-inhibitory domains, whi

92 nslationally active ORFs, and also that most isoforms contain unique combinations of ORFs.

93 In addition, the isoform containing extradomain B enhances the binding of

94 me HDAC and DNA-binding domains and the long isoforms containing a unique N-terminal beta-catenin-int

95 ingly, the relative expression levels of Tau isoforms containing either 3 (3R-Tau) or 4 repeats (4R-T

96 The non-coding ASCC3 isoform counteracts the function of the protein-coding i

97 e-directed expression of the inhibitory CREM isoform CREM-IbDeltaC-X in transgenic mice (TG) leads to

98 in-induced differential expression of VEGF-A isoforms culminates in alterations in gonadotroph functi

99 We show that isoform-D is also expressed selectively, neuroprotective

100 ontrolled expression of either beta-arrestin isoform demonstrate that beta-arrestin2 acts in an oppos

101 of one allele of PTEN is sufficient to shift isoform dependency from p110alpha to p110beta in vivo.

102 Isradipine inhibition was splice variant and isoform dependent, with a 5- to 11-fold lower sensitivit

103 signaling in vivo by producing translational isoforms differing only in the length of the disordered

104 1C gene produces three alternatively spliced isoforms, differing only in their N-terminal regions (NT

105 -residue protein in which the less common E4 isoform differs from the major E3 isoform only by a C112

106 Despite sequence homology across the PAR isoforms, discovery of PAR2 antagonists has been less su

107 of capturing both gene expression levels and isoform diversity at the single-cell level.

108 The Purkinje isoform Dp427p was virtually absent.

109 the associations and trafficking of the CD47 isoforms during erythropoiesis.

110 fied a role of APA in switching Araf protein isoforms during microglia activation, impacting producti

111 e expression of the most abundant PDH kinase isoforms (e.g., PDK3), ameliorating PDH activity and mit

112 actor 1A (EEF1A), is encoded by two distinct isoforms, EEF1A1 and EEF1A2; whereas EEF1A1 is expressed

113 The ER consists of 2 isoforms, ERalpha and ERbeta, which have distinct biolog

114 by Pcdhalphac2, which is the only Pcdhalpha isoform expressed in serotonergic neurons.

115 inner membrane, and Ant2 is the predominant isoform expressed in the liver.

116 These results show that gene isoform expression and allele-specific expression cooper

117 l females eliminates the female-specific Lon isoform expression, Lon proteolytic activity induction,

118 ools to study the link between 3R and 4R-Tau isoform expression, mitotic progression in neuronal prog

119 trix protein, the fibronectin extra domain A isoform (FnEDA), which is relatively restricted in distr

120 sed and purified the three full-length human isoforms from suspension-adapted HEK cells.

121 ntext of progressive depletion of all VEGF-A isoforms from the podocytes.

122 sion involves two heteropolymer-forming FtsZ isoforms: FtsZ1 and FtsZ2 in the green lineage and FtsZA

123 Without these shorter isoforms, full-length MAVS is prone to spontaneous aggre

124 sm cannot apply to CNAbeta1, an atypical CNA isoform generated by alternative 3'-end processing, whos

125 The major protein isoforms generated by P1 and P2 are RUNX1C and RUNX1B, r

126 NA1, expresses an exceptional number of mRNA isoforms generated entirely by alternative splicing in t

127 ynamic association with specific tropomyosin isoforms generates actin filament populations with disti

128 The induced Pabp isoform has shorter 5'UTR removing an auto-inhibitory el

129 Ac-T6-specific targets, suggesting that this isoform has unique cellular functions.

130 However, the contribution of different Ras isoforms has not been investigated.

131 These data reveal that Tcf1 long and short isoforms have distinct, yet complementary, functions and

132 enesis of Alzheimer's disease with its three isoforms having distinct effects on disease risk.

133 tems level by combining slow and fast myosin isoforms heterogeneously.

134 miR-16 family and miR-103/miR-107 within the isoforms HTR4b/i and putatively impairs HTR4 expression.

135 ssion levels of IL-32 alpha, beta, and gamma isoforms, IL1a, IL1b, IL6, IL8, TNFA, PTGS2, CXCR1, and

136 RUNX1C is the most abundantly expressed isoform in adult hematopoiesis, present in all RUNX1-exp

137 The LIG3 gene encodes a ubiquitous isoform in all tissues (LIG3alpha) and a germ line-speci

138 of the non-transposase-encoding mature mRNA isoform in Drosophila germ cells.

139 uous reads are assigned to the most probable isoform in each replicate.

140 telet isoform (PFKP) is the predominant PFK1 isoform in human glioblastoma cells and its expression c

141 e we show that BCAT1 is the predominant BCAT isoform in human primary macrophages.

142 ish a specific requirement for the P1-RUNX1C isoform in megakaryopoiesis, which cannot be entirely co

143 of an endogenous Braf(D631A) kinase-inactive isoform in mice (corresponding to the human BRAF(D594A)

144 verexpression of wild type and mutant 4R-Tau isoform in neuroblastoma SH-SY5Y cell lines is sufficien

145 rized TUBB3, the highly dynamic beta-tubulin isoform in neurons, is essential for netrin-1/UNC5C-prom

146 n ectopic expression of the neuronal ankyrin isoform in non-neural tissues.

147 gene expression profiles of each of the Ras isoforms in a panel of mouse tissues derived from a full

148 n; consequently, the number of functional CA isoforms in a species may exceed the number of genes.

149 In contrast, knocking down either of the PKM isoforms in A549 cells lacking LKB1, a serine/threonine

150 te to an appreciation of the roles of splice isoforms in genetic disorders and suggest that dissectio

151 his study, we specifically ablated Tcf1 long isoforms in mice, while retaining expression of Tcf1 sho

152 partner and signaling opponent of other PKC isoforms in podocytes.

153 lcium channel (VGCC) gene produces two major isoforms in the brain, MPI and MPc.

154 rns and roles in synaptic plasticity for AKT isoforms in the hippocampus.

155 how a functional dichotomy in Class IA PI3K isoforms in these two subsets of CD4(+) T cells can be e

156 the VEGF-A gene produces multiple functional isoforms including VEGF-A165a and VEGF-A165b, a member o

157 the complexity of alternative splicing along isoforms, including 683 intra-molecularly co-associated

158 unteracts the function of the protein-coding isoform, indicating crosstalk between them.

159 How ApoE isoforms influence AD pathogenesis, however, remains unc

160 Various domains of these CARMIL isoforms interact with plasma membranes, vimentin interm

161 Then, we construct the isoform interactome by predicting that an isoform loses

162 The predicted human isoform interactome reveals extensive network remodeling

163 We show that this isoform is also expressed in other differentiated tissue

164 Finally, a non-myristoylated isoform is essential to complete cytokinesis by activati

165 This isoform is highly expressed in advanced stages of breast

166 identity mediated by the common C-type Pcdh isoform is required for axonal tiling and assembly of se

167 The transmembrane VRK2A isoform is retained at the NE by association with A-type

168 Expression of the LOX and LOXL2 isoforms is directly regulated by miR-200 and ZEB1, resp

169 ary structure in the tetrameric apoE3 and E4 isoforms is similar except that some helical segments in

170 y differentiated gonadotropes express a TET1 isoform lacking the N-terminal CXXC-domain, which repres

171 se the proapoptotic effect of the IL-32gamma isoform, leading to tumor cell survival and thus favorin

172 t is important to evaluate expression at the isoform level.

173 g the importance of studying ASE at the gene isoform level.

174 ut have not studied their concordance at the isoform level.

175 yping and (ii) estimation of ASE at the gene isoform level.

176 LIG3alpha) and a germ line-specific splicing isoform (LIG3beta) that differs in the C-terminal domain

177 carboxysome shell protein, RuBisCO, and CcmM isoform localization.

178 Various isoforms localized to different regions of the pollen tu

179 he isoform interactome by predicting that an isoform loses an interaction if it loses the domain medi

180 sues, the structural similarity of the three isoforms makes this divergence perplexing.

181 ulature (NHE1 isoform) and the kidneys (NHE3 isoform) may serve as a common mechanism that links both

182 lnerability upon targeting of its paralogous isoform ME3.

183 nd CRMP/UNC-33, but is suppressed by the Rac isoform MIG-2; (2) RPM-1 opposes the function of microtu

184 s are differentially regulated by individual isoforms, necessitating a deeper understanding of how th

185 nly when presented as the tissue-specific M1 isoform, not when presented as the ubiquitously-expresse

186 Repletion of this isoform of Agrin in the motor neurons of SMA model mice

187 sition (Rb-positive and low-molecular-weight isoform of cyclin E (cytoplasmic)-negative) is a reliabl

188 muscle maturation, BIN1 had no effect on the isoform of DNM2 found in adult muscle.

189 Unlike humans, rodents express a novel isoform of ERbeta (mERbeta2) with a modified ligand-bind

190 tamate Transporter 1 (VGLUT1) and the 65 kDa isoform of glutamic acid-decarboxylase (GAD65) as marker

191 tment of an approximately 600-kDa endogenous isoform of Nesprin1 (Nes1(600kDa)) and of Sun2.

192 To date, the role of the mitochondrial isoform of OGT (mOGT) remains largely unknown.

193 ydroxylase 2 (PHD2) transgene, a predominant isoform of PHDs in renal tubules, to reduce HIF-1alpha l

194 ue, Webb et al. show that the liver-specific isoform of phosphofructokinase-1 forms filaments in vitr

195 PKCalpha is a conventional isoform of PKC and a well-known binding partner of beta-

196 protein product of which recruits the alpha-isoform of protein phosphatase 1 catalytic subunit (PP1a

197 enoviral vector encoding a dominant negative isoform of Src homology region 2 domain-containing tyros

198 Here, we show that an alternatively spliced isoform of syntaphilin (SNPH), a cytoskeletal regulator

199 hat CaV 3.1 is the most abundantly expressed isoform of T-channels in the rat subiculum.

200 sm was dependent on the expression of a long isoform of the bacterial enzyme cytidine deaminase (CDDL

201 ell lines and mouse models containing either isoform of the gamma-subunit in the heart.

202 Mena(INV), an isoform of the motility regulator protein Mena, contribu

203 PrP(C), the cellular isoform of the prion protein, serves to transduce the ne

204 ependent, unforeseen function of the nuclear isoform of the Receptor for Advanced Glycation End-produ

205 er regulator of HBC activation is the DeltaN isoform of the transcription factor p63; eliminating Del

206 a protein-coding ASCC3 mRNA to a shorter ALE isoform of which the RNA, rather than an encoded protein

207 We identified all three isoforms of Ca(2+) -activated small conductance K(+) (SK

208 rent is likely conducted by short C-terminal isoforms of Cav1.3 channels, notably Cav1.342A and Cav1.

209 As the functional roles of the three major isoforms of dysbindin-1, (A, B, and C) remain unknown, w

210 dies, which recognize tumor-selective splice isoforms of fibronectin (F8-TNF), can be exploited to er

211 ts encoding distinct nuclear and cytoplasmic isoforms of fusilli, the D.

212 ested as inhibitors against muscle and liver isoforms of glycogen phosphorylase (GP).

213 ruitment of a subset of expressed miRNAs and isoforms of miRNAs (isomiRs) to the miRISC in response t

214 in fibroblasts, we demonstrate that multiple isoforms of Nesprin1 are integral components of ciliary

215 at different PKMs, the constitutively active isoforms of PKCs generated by calpain cleavage, in the s

216 hieve high binding selectivity for different isoforms of this protein family.

217 ent counteraction of both the long and short isoforms of this restriction factor.

218 Different variants or isoforms of tropomyosin, arginine or creatine kinase, gl

219 The splice isoforms of vascular endothelial growth A (VEGF) each ha

220 In this manner, the effects of each isoform on cell fate can be simultaneously assessed thro

221 common E4 isoform differs from the major E3 isoform only by a C112R substitution.

222 One isoform, Orb2A, has a unique N-terminus that has been sh

223 out shifts splicing toward the fully spliced isoform, our data are consistent with a model in which u

224 e in Quantification of Alternatively Spliced Isoforms, outperform other available transcriptomes in R

225 ambon et al. reinvestigated how three myosin isoforms participate in the formation and constriction o

226 Here, we demonstrate that PFK1 platelet isoform (PFKP) is the predominant PFK1 isoform in human

227 AKAP150, the most well-characterized isoform, plays an important role in several forms of neu

228 rs and that RIM2alpha is the major large RIM isoform present at photoreceptor ribbon synapses.

229 rtant 'marker of self' protein with multiple isoforms produced though alternative splicing that exhib

230 Conversely, the imbalance toward the 4R isoform promoted a retrograde bias by a significant redu

231 t at RUNX3 decreasing IgA levels by shifting isoform proportions (rs188468174[C>T]: P = 8.3 x 10(-55)

232 Its misfolded isoform PrP(Sc) is the causative agent of prion diseases

233 rP(C) misfolding into the disease-associated isoform, PrP(res), as well as prion propagation and infe

234 ng of IgE to five recombinant beta-conglutin isoforms (rbeta) that we overexpressed and purified and

235 mics in both apo- and holo-forms of the HCN4 isoform, reflecting how S672R remodels the free energy l

236 sue and stage-specific expression of ankyrin isoforms relies on differential activity of positive and

237 Instead, transcription of this isoform represses the canonical NDC80 mRNA expression in

238 detection of currently unmeasurable protein isoforms responsible for cancer progression.

239 Specific loss of the 9000 amino acid long isoform results in vesicle clustering defects and increa

240 als, resulting in regulatory approval of one isoform-selective inhibitor (idelalisib) for treatment o

241 The exquisite isoform selectivity of lynx1 interactions provides new i

242 Seven SGLT isoforms (SGLT1 to 6 and sodium-myoinositol cotransporte

243 is expressed in multiple isoforms, with all isoforms sharing the same HDAC and DNA-binding domains a

244 suggest that both smaller apolipoprotein(a) isoform size and increased lipoprotein(a) concentration

245 nt associated with smaller apolipoprotein(a) isoform size, but not lipoprotein(a) concentration, and

246 (a) concentration, but not apolipoprotein(a) isoform size.

247 rent and voltage, we identified all three SK isoforms (SK1, SK2 and SK3) in mouse SAN.

248 se signaling pathway, resulting in time- and isoform-specific endothelial and neuronal nitric oxide s

249 Using DREAM-null platelets and PI3K isoform-specific inhibitors, we observed that platelet D

250 atory or inhibitory synaptic functions in an isoform-specific manner.

251 ation of the Orai N terminus and loop2 in an isoform-specific manner.

252 Isoform-specific mechanisms of alpha3beta4*-nicotinic ac

253 A large panel of common and isoform-specific peptides was monitored by multiplex LC-

254 el configuration of connexins (Cxs) displays isoform-specific permeability profiles that are not dire

255 ling previously undetected gene products and isoform-specific protein expression.

256 These HSA-Abeta interactions are isoform-specific, because the HSA affinity of Abeta mono

257 Here, we discovered that KCNQ2/3 channels isoform-specifically colocalize with SMIT1 and SMIT2 at

258 JAK3 specific inhibitor, which achieves JAK isoform specificity through covalent interaction with a

259 n determining NDE1 species specific splicing isoforms supporting the notion that alternative splicing

260 The main steps of TSIS are to search for the isoform switch points in the time-series, characterize t

261 st tool for detecting significant transcript isoform switches in time-series data.

262 nstrate that largazole and its analogues are isoform-targeted histone deacetylase inhibitors and pote

263 ed greater 3' UTR size differences among APA isoforms than did S. cerevisiae PASs in different locati

264 al activity, and Ser5-001 is the predominant isoform that contributes to the activity.

265 Methanococcoides burtonii contains a Rubisco isoform that functions to scavenge the ribulose-1,5-bisp

266 sulting in synthesis of a novel M187 spastin isoform that is able to sever microtubules.

267 TC), that leads to a 65kDa truncated protein isoform that opposes full-length eIF2Bepsilon to inhibit

268 vation of glutamic acid decarboxylase enzyme isoforms that convert glutamate to GABA.

269 g probes for the murine and human granzyme B isoforms that specifically and quantitatively bind granz

270 Synechococcus elongatus, CcmM, occurs in two isoforms thought to localize differentially within the c

271 uction of both nuclear and cytoplasmic Esrp1 isoforms through alternative splicing is phylogeneticall

272 These three isoforms thus represent potential targets for therapeuti

273 s and the ability of the various domains and isoforms to bind to a variety of integrins result in a w

274 e scaled expression levels of all transcript isoforms to follow the same Weibull extreme value distri

275 rimed DCs, induced higher levels of both IDO isoforms together with the transcription factor aryl-hyd

276 that CDM-relevant exons undergo prenatal RNA isoform transitions and are predicted to be disrupted by

277 ariation on the regulation of transcription, isoform usage, and allele-specific expression.

278 ults in production of proangiogenic VEGFxxxa isoforms (VEGF165a, 165 for the 165 amino acid product)

279 ity of mAbs 5B4 and 6H4 to recognize Bet v 1 isoforms was addressed by immunochromatography.

280 ions on the enzymatic behavior of individual isoforms, we overexpressed and purified the three full-l

281 Notably, more than 42 280 distinct splicing isoforms were derived from 128 667 intron-containing ful

282 analysis demonstrated that cytoplasmic LANA isoforms were full length, containing the N-terminal nuc

283 No shorter ALT isoforms were identified.

284 The N. alopecuroidea and N. minor CA1a isoforms were imported into chloroplasts of Nicotiana be

285 sm, which splices the RCA-alpha and RCA-beta isoforms were probably gained from another gene in charo

286 In contrast, Tcf1 long isoforms were required for differentiation of T follicul

287 293A cells transiently transfected with mER isoforms were used to detect EDC-mediated changes in end

288 compensatory up-regulation of the two other isoforms, which allows maintenance of total actin levels

289 o structural dissimilarities between the two isoforms, which can potentially lead to functional diffe

290 ersely, our results suggest that Cav1.3 long isoforms, which carry approximately 75% of the total IHC

291 and developmental stages validated two such isoforms, which differ in the utilization of an internal

292 Hig1 type 2 isoforms, which include the Rcf1 protein, are characteri

293 ain expressed the constitutively active PKM1 isoform, while neural progenitors and medulloblastomas e

294 cript per million (TPM) levels for genes and isoforms with confidence intervals through bootstrapping

295 age and polyadenylation (APA) generates mRNA isoforms with different 3' untranslated regions (3'UTRs)

296 resses both coding and non-coding transcript isoforms with opposite effects on transcription recovery

297 tau primary transcript gives rise to protein isoforms with three (3R) or four (4R) MT binding repeats

298 ogesterone via PR-A, but not the longer PR-B isoform, with increased progesterone sensitivity when PR

299 Tcf1 is expressed in multiple isoforms, with all isoforms sharing the same HDAC and DN

300 thelial C' inhibitors (C' receptor-1 related isoform Y and decay accelerating factor), and an increas