ライフサイエンスコーパス: isogenic strain

1 ed fungal traits, relative to the virus-free isogenic strain.

2 yeast strain at 90% the rate of a wild-type isogenic strain.

3 d laboratory parasites as well as across non-isogenic strains.

4 the underlying genetic lesions, and generate isogenic strains.

5 strain tested, including identically reared, isogenic strains.

6 an experimental population composed from 20 isogenic strains.

7 f an IS6110-mediated deletion event in truly isogenic strains.

8 ed replication rate in amoebae compared with isogenic strains.

9 ated in piglets and mice using GGT-deficient isogenic strains.

10 set of conditionally growth-defective/lethal isogenic strains.

11 Reconstruction of isogenic strains also showed that the IS150 insertions i

12 Previous data generated using non-isogenic strains and transfection models suggest that va

13 Variation within isogenic strains appears to be generated mainly by devel

14 An isogenic strain bearing a kanamycin insertion in mtaR wa

15 estored the fucosylation program, whereas an isogenic strain carrying a transposon insertion that dis

16 pendent on CorA for Mg(2+) uptake but not of isogenic strains carrying a second Mg(2+) uptake system.

17 Isogenic strains carrying either no plasmid, wild-type p

18 Isogenic strains carrying in-frame deletions in genes re

19 We showed that isogenic strains carrying mutations in luxS(Hp), cysK(Hp

20 Importantly, the repaired isogenic strain colonized the mouse oropharynx with sign

21 an average 6-fold decreased GAS recovery in isogenic strain competition assays.

22 Engineered polymorphisms in isogenic strains confirmed an interaction between the ma

23 ch precolonized strain nearly eliminated its isogenic strain, confirming that colonization resistance

24 A recent study with isogenic strains constructed by recombinant DNA strategi

25 The corresponding isogenic strain containing ccaR:gfp in the chromosome pr

26 Although the levels of virulence of isogenic strains containing either nt 5 A or nt 5 G did

27 Isogenic strains containing either the complete phoB pro

28 n vivo activities of all eight pheromones on isogenic strains containing four different ComP receptor

29 Isogenic strains containing specifically disrupted flaAl

30 ow levels of these self-poisoning enzymes in isogenic strains defective for the Rad9 DNA damage check

31 Two sets of isogenic strains deficient in SpeB cysteine protease act

32 Using three isogenic strains derived from PRV263, each expressing a

33 Y. pestis psaA isogenic strains did not show any significant difference

34 -toxin in experimental endocarditis by using isogenic strains differing in the capacity to produce fu

35 nd respiratory tract infection in mice using isogenic strains differing only in SpyCEP expression.

36 expressed during starvation in two otherwise-isogenic strains differing only in their H1s.

37 tly increased compared to that of cells from isogenic strains expressing active PBP 5.

38 h the hemolysin structural gene deleted, and isogenic strains expressing different amounts of hemolyt

39 Using isogenic strains expressing either meningococcal fHbp or

40 However, in murine infection models, isogenic strains expressing the two delta-toxin variants

41 survival defect more pronounced than that of isogenic strains harbouring single mutations.

42 Infection studies with isogenic strains having defined toxin deletions have est

43 with 0.5% rifampin- and isoniazid-resistant isogenic strains in some experiments.

44 In contrast, an isogenic strain lacking Shiga toxin induced similar but

45 ntext of the live bacterium by generating an isogenic strain lacking the scl-1 gene.

46 In contrast to wild-type UPEC, an isogenic strain lacking ybcL expression (UTI89 DeltaybcL

47 ased PNAG and biofilm production relative to isogenic strains lacking the plasmid.

48 e (NSR) of wild type S. meliloti Rm1021, and isogenic strains missing both PII proteins, GlnB and Gln

49 ential growth without cell lysis, whereas an isogenic strain mutated in a peptidoglycan hydrolase gen

50 y to disruption of ompCD by constructing the isogenic strain O35E.CD1.

51 ed a high fat/sugar water-induced animal (an isogenic strain of C57BL/6 J:129S1/SvImJ mice) model of

52 e report transmission of an azole-resistant, isogenic strain of Candida albicans in a human immunodef

53 In contrast, in mice infected with an isogenic strain of pneumococci lacking PspA, significant

54 A/J lacking T and NK cells), and SK(-/-) (an isogenic strain of strain C57BL6/J lacking SK1), to inve

55 L6/J (both immunocompetent), Tgepsilon26 (an isogenic strain of strain CBA/J lacking T and NK cells),

56 Our aim was to use two isogenic strains of a neurotropic virus (pseudorabies, B

57 he amount of serotype 1 or 5a CP produced by isogenic strains of A. pleuropneumoniae correlated with

58 Isogenic strains of Agrobacterium tumefaciens carrying p

59 catalase in CGD directly, we have generated isogenic strains of Aspergillus nidulans in which one or

60 xtracellular proteomes (secretomes) of three isogenic strains of B. anthracis that differed solely in

61 h inactivated HWP1 genes, whereas mice given isogenic strains of C. albicans that had a single copy o

62 e cantilever tip and confluent monolayers of isogenic strains of Escherichia coli mutants exhibiting

63 We tested this hypothesis by creating isogenic strains of gliotoxin-producing and nonproducing

64 lets from six litters were given one of four isogenic strains of H. pylon orally.

65 expression in three selected lines, and six isogenic strains of mice known to differ markedly in vol

66 orsal lateral geniculate nucleus (LGN) in 58 isogenic strains of mice.

67 Construction of genetically isogenic strains of mycobacteria is complicated by poor

68 oach was applied to Tn-Seq libraries made in isogenic strains of Mycobacterium tuberculosis lacking t

69 Isogenic strains of PAO1 that lacked surface adhesins we

70 For this purpose, recombinant isogenic strains of PRV were injected into these respira

71 e transneuronal transport of two recombinant isogenic strains of pseudorabies virus.

72 ssions from seven species of Lycopersicon to isogenic strains of Pst differing in the presence of avr

73 memory CD8 T cells were coinfected with two isogenic strains of recombinant Listeria monocytogenes t

74 ptic arthritis by comparing the virulence of isogenic strains of S. aureus expressing (1) wild-type C

75 Mice were gavaged with 2 isogenic strains of S. typhimurium after administration

76 H1, MLH2, MSH2, MSH3, MSH6, but not PMS1) in isogenic strains of Saccharomyces cerevisiae led to incr

77 f each gene in virus-infected and uninfected isogenic strains of the fungus by using nuclear run-on a

78 transcriptional profiling of infection with isogenic strains offered a detailed molecular picture of

79 alent inhibitory effects of SAL on a pair of isogenic strains, one of which was a polysaccharide/adhe

80 -1beta) in mice, similar to what occurs with isogenic strain P4 (DeltactxAB), but is less virulent an

81 We created three isogenic strain pairs (serotypes 3, 4, and 24) that diff

82 type 2 S. pneumoniae strain D39, or with the isogenic strain PLN, which does not express pneumolysin.

83 nasopharyngeal isolates express pili, while isogenic strains recovered from the middle ear are often

84 ative analysis of proteins isolated from the isogenic strains revealed that growth phase-associated r

85 Fluorescent protein-based differentiation of isogenic strains revealed that priority of gut colonizat

86 Candq1 and its candidate genes to create an isogenic strain set with large differences in collateral

87 Notably, our results differ from non-isogenic strain studies, thus highlighting the importanc

88 Our data obtained using isogenic strains suggest that the liaS(R135G) mutation i

89 do display enhanced resistance to a virulent isogenic strain that lacks the avirulence gene.

90 Furthermore, we generated isogenic strains that allowed us to establish that Exigu

91 Using isogenic strains that carry a temperature sensitivity al

92 a field experiment comparing the fitness of isogenic strains that differ in the presence or absence

93 Comparing isogenic strains that differ only in their ability to in

94 f the organisms compared to the virulence of isogenic strains that do not overexpress SrrAB.

95 ss this discordance, we constructed a set of isogenic strains that enabled us to inhibit selectively

96 While the adhesive abilities of Opa-Pil+ isogenic strains that express LOS molecules lacking the

97 omoter by a variety of phenolic compounds in isogenic strains that express or lack virH1 and virH2.

98 We report the construction and use of four isogenic strains that lack nitrate reductase Z and the p

99 In competition experiments using isogenic strains, the strain with the insertional allele

100 s (FnBPs); the capacity of an FnBP-deficient isogenic strain to invade HCEC was reduced by more than

101 s, thus highlighting the importance of using isogenic strains to study the role of CagA toxin polymor

102 The "repaired" isogenic strain was significantly more virulent than the

103 ment (P[lArB]) insertional mutagenesis of an isogenic strain was used to identify autosomal loci affe

104 The colony-forming potential of 10 isogenic strains was defined as a function of time spent

105 The results indicated that all K88+ isogenic strains were able to colonize the small intesti

106 nsertion of an Omega kanamycin cassette, and isogenic strains were constructed.

107 The isogenic strains were found to be equally capable of blo

108 of CovRS in the virulence of AP53, two AP53 isogenic strains were generated, one in which the natura

109 Coinoculation of an isogenic strain which produced the endogenous HHL signal

110 growth rate by up to 100-fold relative to an isogenic strain with normal editing function.

111 derived macrophages as well as did otherwise isogenic strains with a wild-type rpoS allele.

112 The capacities of isogenic strains with an insertion mutation in emm49; wi

113 onditions that led to germ tube formation in isogenic strains with CAP1.

114 In vitro treatment of clinical and isogenic strains with ciprofloxacin increased the produc

115 Several isogenic strains with defects in recombination/repair ge

116 Two isogenic strains with identical growth kinetics at 35 de

117 Isogenic strains with mutations in ftpA or losB bound as

118 Here we compared isogenic strains with naturally occurring mtrR locus mut

119 In comparison to a wild-type strain, isogenic strains with null mutations in either HP0165 or

120 c E. coli was examined by comparing adherent isogenic strains with or without STb.

121 id A-modifying genes into 18-323 to generate isogenic strains with varying penta-acyl lipid A structu