ライフサイエンスコーパス: isoleucine residue

1 functionality depends on the presence of an isoleucine residue.

2 aline, and the indistinguishable leucine and isoleucine residues.

3 formation with a hinge region around the two isoleucine residues.

4 lkyl aryl ether linkage between the dopa and isoleucine residues.

5 Both the deletion of the isoleucine residue 141 and its substitution to valine in

6 ucine residue and the other a deletion of an isoleucine residue (881).

7 n bonds involving the methyl groups of three isoleucine residues and the O2 and N3 atoms of the two c

8 Leucine and isoleucine residues are readily distinguished in L-Ala-L

9 in one allele, which leads to the loss of an isoleucine residue at codon 141, and a 423A-->G transver

10 man population response were dependent on an isoleucine residue at position 129.

11 In addition, we show that the mutating the isoleucine residue at position 44 interferes with protea

12 Mutation of the isoleucine residue at position 49 to glycine (I49G) redu

13 of vertebrate insulins contains an invariant isoleucine residue at position A2.

14 nding PDZ domains is the accommodation of an isoleucine residue at the C-terminal position (P(0)), a

15 mino acid 97, we systematically replaced the isoleucine residue at this position with 18 other amino

16 impacts were specific to substitutions with isoleucine residues because functional modulation was pa

17 The mutation is the deletion of an isoleucine residue from a highly conserved hydrophobic d

18 Targets included adjacent aspartate/isoleucine residues implicated as important for determin

19 Disruption of either isoleucine residue in the eIF1A C-terminal sequence DIDD

20 Mutation of a highly conserved isoleucine residue in the FH2 domain does not inhibit bu

21 biophysical approaches, we have uncovered an isoleucine residue in the kinase domain of the Tec famil

22 f Keap1 comprised of hydrophobic leucine and isoleucine residues in agreement with a traditional NES

23 1, C(gamma)2, and C(delta) shifts in the two isoleucine residues in bovine pancreatic trypsin inhibit

24 ments were made at five different leucine or isoleucine residues in the alpha subunit of tryptophan s

25 ondary structure, the hydrophobic triplet of isoleucine residues in the center of the IC3 is found in

26 that the first layer of the highly conserved isoleucine residues in the filter is primarily responsib

27 The altered isoleucine residue lies within the third conserved alpha

28 r Waals interactions with either a valine or isoleucine residue located either seven or eight residue

29 results suggest that the targeted aspartate/isoleucine residues may contribute to regulator binding

30 les describing retroviral cleavage sites, an isoleucine residue placed at the P1 position of the NC-P

31 of serotonin transporter (SERT) contains two isoleucine residues previously proposed to be involved i

32 Rho GTPases due to a distinctive switch one isoleucine residue reminiscent of the constitutively act

33 tightly packed hydrophobic core, clusters of isoleucine residues, salt-bridges, and the presence of p

34 In particular, we have focused on an isoleucine residue that interacts with the adenine moiet

35 an allosteric communication with a conserved isoleucine residue that lines the binding channel for hi

36 id residue to aspartic acid, or changing the isoleucine residue that precedes the motif to proline, p

37 To mimic interacting leucine and isoleucine residues, we have created new amino acids tha

38 arameters for all methyl groups of the seven isoleucine residues were determined.

39 sis showed that more than 93% of the encoded isoleucine residues were replaced by 5TFI.

40 to-cell fusion, the six heptadic leucine and isoleucine residues were replaced with alanine by site-d

41 n two of the four middle heptadic leucine or isoleucine residues were replaced with alanine.

42 d w-type ions, 45 of 50 detected leucine and isoleucine residues were successfully distinguished and

43 cids in the range from valine to leucine and isoleucine residues, will be more robust in the face of

44 gammaB-crystallin gene that replaces the 4th isoleucine residue with a phenylalanine (gammaB-I4F).

45 Moreover, mutation of the isoleucine residue within an NPIR-like motif of the prop

46 anine or a serine substitution at a critical isoleucine residue within the zipper region were also ge

47 is of the HeV G stalk, targeting a series of isoleucine residues within a hydrophobic alpha-helical d

48 f helix-destabilizing, ss-branched valine or isoleucine residues within the TMD restores normal secre