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1 nsion cost decreased throughout steady-state isometric force.
2 /s, then was constant at 3.26 +/- 0.06 times isometric force.
3 in small-vessel myographs for measurement of isometric force.
4 initial force was raised to 75-80% of steady isometric force.
5 ording intracellular electrical activity and isometric force.
6 rsal of the power stroke, thereby increasing isometric force.
7 ta-cardiac myosin but a 2-fold lower average isometric force.
8 ivated force in the range 0.3-0.8 of maximum isometric force.
9    Work and power were compromised more than isometric force.
10 , thereby ensuring effective transfer of OHC isometric forces.
11 PD and non-COPD fibres that produced similar isometric forces.
12 o slower components by 50%, in proportion to isometric force, (2) adding a non-relaxing component and
13 electrode, intracellular microelectrode, and isometric force (a surrogate marker for the Ca2+ transie
14      In five healthy adults, we recorded the isometric forces acting a hand joint and the electromyog
15                                              Isometric force, actomyosin ATPase activity, and unloade
16                              We measured the isometric force and actin filament velocity for native p
17                                  We measured isometric force and ATP utilization at different calcium
18                     We measured steady-state isometric force and ATPase activity in detergent-skinned
19                         Endothelin increases isometric force and decreases actomyosin ATPase activity
20 s of BS and OM on the calcium sensitivity of isometric force and filament structural changes suggest
21        We investigated the relations between isometric force and intracellular calcium concentration
22 creases in fibre number, 20-57% increases in isometric force and no differences in specific force.
23 scle fibers developed greater than twice the isometric force and power output of young fibers, yet cr
24 ated to yield 50% maximal force, after which isometric force and rate constants (k(tr)) of force deve
25 f phosphorylation at Thr(18) on steady-state isometric force and relaxation rate were investigated in
26  microM phalloidin for 1 h, the increases in isometric force and stiffness were not sustained despite
27 s on force and fiber shortening by measuring isometric force and stiffness, the rate of tension decli
28                                              Isometric force and surface EMG signals were recorded fr
29 ed quadriceps and handgrip maximum voluntary isometric force and the relaxation times, force-frequenc
30 rs, as measured by their ability to generate isometric force and to hydrolyze ATP by actomyosin Mg2+
31 TP, 2-deoxy ATP (dATP), CTP, and UTP support isometric force and unloaded shortening velocity (Vu) to
32 ent activation (fractional calcium binding), isometric force, and the rate of force generation in mus
33 elocity by 58% and enhanced the myosin-based isometric force approximately 2-fold.
34 ly switched from that for motion to that for isometric force approximately 65 ms before contact (p =
35 G mouse hearts expressing ssTnI and measured isometric force at extracellular pH 7.33 and pH 6.75.
36 -10 degrees C) but much larger than that for isometric force at higher temperature (1.3 at 20-25 degr
37  The average (extrapolated) value of maximum isometric force at low kinesin density was 0.90 +/- 0.14
38 5 degrees C; this was similar to the Q10 for isometric force at low temperature (3.5 at 7-10 degrees
39               Three millimolar BDM decreased isometric force by 50%, velocity by 29%, maximum power b
40 lue indicates that the myosin head generates isometric force by a small sub-step of the 11 nm stroke
41 ame assay could be used to determine average isometric force by loading the actin filaments with incr
42 on, RLC phosphorylation enrichment increased isometric force by more than 3-fold and peak power outpu
43  5), the normalised tendon strain at maximum isometric force (c) (varied from 0 to 0.08), the muscle
44  acting as a lever, while the enhancement in isometric force can be directly related to enhancement o
45 ibits significantly reduced maximum specific isometric force compared with littermate controls.
46 nt atrophy and impairment of specific force (isometric force/cross-sectional area) and unloaded short
47 sed from 2.3 microm to 2.0 microm submaximal isometric force decreased approximately 40% in both alph
48 100 pmol/L and 10 nmol/L endothelin-1 raised isometric force, decreased actomyosin ATPase activity, a
49                 Histological and functional (isometric force deficit) signs of muscle injury and tota
50 r decrease in Ca(2+) sensitivity and maximal isometric force development compared with the R141W muta
51 k(tr) measurements underestimate the rate of isometric force development during submaximal Ca2+ activ
52                           The time course of isometric force development following photolytic release
53 troponin C (HCTnC), and the Ca(2+) dependent isometric force development of these troponin-replaced f
54                                       During isometric force development, growing cross-bridge tracti
55 ch lower specific force, and slower rates of isometric force development, slow phase relaxation, and
56 ities, which can be significant, even during isometric force development.
57 , maximal force and k(tr) and the pCa(50) of isometric force did not differ between WT and cMyBP-C(-/
58            In the present study, we measured isometric force during EPR spectral acquisition, in orde
59 n cost (i.e. ATP hydrolysis rate per unit of isometric force) during Ca2+-induced activation of Trito
60       The tension increased to 2- to 3 x P0 (isometric force) during ramp lengthening at velocities >
61 the steady-state value of F approximated the isometric force, E was large, and eta was small.
62                                          The isometric force elicited by voltage pulses under whole-c
63                                  The average isometric force exerted by each attached myosin head at
64 ases both the unloaded sliding speed and the isometric force exerted by myosin heads on the thin fila
65 rements of the unloaded sliding speed of and isometric force exerted on single thin filaments in in v
66 as calculated as the decrease in the maximum isometric force expressed as a percentage of the maximum
67                                      Maximal isometric force (F(0)) decreased from 91.0 +/- 1.9 to 58
68 ere paralleled by increases of 30% to 80% in isometric force (F(max)), rate of tension redevelopment
69                  At maximal Ca2+ activation, isometric force (Fi) was inhibited at the highest solute
70  such building blocks have been described as isometric force fields.
71 , we demonstrate a >40% increase in specific isometric force following repeated administrations.
72                             Redevelopment of isometric force following shortening of skeletal muscle
73  match a target force at 2% of their maximal isometric force for 35 s with abduction of the index fin
74 of fatigue, induced by production of maximal isometric force for 60 s with four fingers, upon indices
75 er, the small rodent generates the same high isometric force for both alpha and beta isoforms.
76 egment is stretched and a deficit in maximum isometric force (force deficit) is produced, the regions
77                                   The active isometric force, force-velocity relationship, and force
78                                      Maximal isometric force generated by the big toe declined to 78.
79                   The model accounts for the isometric force generated by the cell and explains the o
80 e tension-pCa relationship or in the maximum isometric force generated.
81 ized as a force field: the collection of the isometric forces generated at the ankle over different l
82                               Therefore, the isometric force generating capacity of airway smooth mus
83 himpanzees does not stem from differences in isometric force-generating capabilities or maximum short
84 rformance differential have included greater isometric force-generating capabilities, faster maximum
85 on returned nearly to control levels, as did isometric force generation and rate of ATP hydrolysis.
86 end of the latency relaxation (LR) preceding isometric force generation, approximately 10 ms after th
87 end of the latency relaxation (LR) preceding isometric force generation, approximately 10 ms after th
88 vement without vision, passive movement, and isometric force generation.
89 ncreasing levels of unilateral and bilateral isometric force in a sitting position.
90  a powerful inotropic peptide that increases isometric force in isolated papillary muscle and the ext
91 ongly dependent on sarcomere length than was isometric force in the range 1.5-2.5 microm.
92  resting sarcomere length similar to that of isometric force in the range 2.5-4.0 microm, but was les
93 oduce force using a novel optical-trap-based isometric force in vitro motility assay.
94 actin filament velocities and higher average isometric forces (in an in vitro motility assay) when co
95                 At maximum Ca(2+) (pCa 4.5), isometric force increased linearly with dATP/ATP ratio,
96 ing stroke responsible for the generation of isometric force is a larger fraction of the total myosin
97                  We conclude that fibroblast isometric force is not coupled to Ca2+ arising from tran
98 ter value was normalised for the decrease in isometric force, it became 2.56 +/- 0.3 mM s(1), which i
99                     The influence of Ca2+ on isometric force kinetics was studied in skinned rat vent
100 ament compliance to sarcomere compliance and isometric force kinetics, the Ca(2+)-activation dependen
101 omycin inhibits myogenic tone and K+-induced isometric force largely by blockade of L-type, dihydropy
102                                          The isometric force-length curve for mdx muscle was steeper
103        To test this possibility, we compared isometric force, loaded shortening velocity, and power o
104 vasive measurement of airway resistance, and isometric force measurements in isolated bronchial rings
105            Intracellular microelectrodes and isometric force measurements were used to measure vasopr
106 ith intracellular microelectrode recordings, isometric force measurements, Kit-like immunohistochemis
107 atch clamp, intracellular microelectrode and isometric force measurements.
108  30% of the velocity and produced 65% of the isometric force of cells reconstituted with the thiophos
109 atin not only increases the mass and maximum isometric force of muscles, but also increases the susce
110 ded in organ chambers for the measurement of isometric force or frozen for isolation of membrane prot
111 in had no effect on Vmax during steady-state isometric force or on rMLC phosphorylation.
112 ls were reduced to approximately 70% maximal isometric force (P4.5) in cardiac myocyte preparations,
113 ontraction, but as the fibres approached the isometric force plateau they showed little IS sensitivit
114 show that the effects of both GCs on maximum isometric force (Po) were fibre-type dependent.
115                                          The isometric force produced by glycerinated muscle fibers w
116 uced by 27.5 +/- 5.0% (P < 0.05), whilst the isometric force produced by the EDL-TA muscle group was
117                       Direct measurements of isometric force production in single cardiac myocytes de
118 rylation on Ca(2+) dependence of myofilament isometric force production, isometric ATPase rate, and t
119 cquired during walking, reaching, flying, or isometric force production.
120  of unloaded thin filament sliding speed and isometric force production.
121     Elevated levels of phosphate (Pi) reduce isometric force, providing support for the notion that t
122 eshold force of units for recruitment during isometric force ramps in many different directions.
123 rteries were suspended in organ chambers for isometric force recording.
124                                              Isometric force recordings of single cardiac myocytes de
125                  Thin-filament regulation of isometric force redevelopment (k(tr)) was examined in ra
126 ted in a leftward shift of the concentration-isometric force relations for both aorta types, as expec
127                 The cumulative concentration-isometric force relations for the PLB- aorta were to the
128                                  Contraction-isometric force relations in response to phenylephrine o
129  aorta, phenylephrine and KCl concentration- isometric force relations in the presence or absence of
130                Aortic rings were excised and isometric force responses to phenylephrine, acetylcholin
131 of P(i)/mol of LC(20)) and similar levels of isometric force revealed differences in the rates of dep
132 ogether with the increased sliding speed and isometric force seen in the presence of regulatory prote
133  measured the time course of [Ca(2+)](i) and isometric force simultaneously in an intact artery after
134 roM free Ca2+ induced sustained increases in isometric force, stiffness, and rMLC phosphorylation.
135 ous and endogenous NO on murine fundus using isometric force studies.
136 itro motility assay, or the relative average isometric force supported by F-actin.
137 V0 shortening is superimposed on the maximum isometric force T0 , n decreases progressively with the
138 electrodes and contractions were recorded by isometric force techniques.
139  thin filament sliding speed but reduced the isometric force that heavy meromyosin exerted on regulat
140 lue of the muscle force, F, approximates the isometric force, the muscle stiffness, E, is large, and
141 nt with PI(3,5)P2 increased the magnitude of isometric force, the rate of force development, and the
142 ; (2) rapid movement to position target; (3) isometric force to a target level; and (4) adaptation to
143 tone of smooth muscle strips was measured by isometric force transducers.
144 membranated sperm assay we estimated maximum isometric force using a laser trap-based assay.
145                        In the absence of Tm, isometric force was a linear function of the density of
146                                     Thus the isometric force was approximately proportional to the ax
147                                              Isometric force was directly recorded from individual hy
148                                              Isometric force was measured over a wide range of calciu
149                                              Isometric force was nearly the same at all lengths.
150                                              Isometric force was not different between the two groups
151                                              Isometric force was not improved but the resistance to e
152 rol mice, but no reduction in muscle mass or isometric force was observed in SynTgSod1(-/-) mice comp
153                                              Isometric force was recorded from strips of ferret aorta
154 09 ms (mean +/- s.e.m.) to 113 +/- 17 ms and isometric force was reduced to 63 +/- 3% of the initial
155                    The Ca(2+) sensitivity of isometric force was significantly greater for V95A and E
156 5% so that its relative amplitude (amplitude/isometric force) was increased by 75%.
157 active isometric tension curve and developed isometric force were studied.
158 at physiological temperatures, a decrease in isometric force, which mainly indicates a reduction in t
159 ng the Ca sensitivity of ATPase activity and isometric force, which were both completely restored by
160 ibly and concentration-dependently inhibited isometric force with an IC50 of 1.71 mM.

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