ライフサイエンスコーパス: isometric tension

1 bore 34%, 64%, and 2%, respectively, of the isometric tension.

2 long axis, was monitored simultaneously with isometric tension.

3 RLC phosphorylation, and 3) the decrease in isometric tension.

4 mulated increases in RLC phosphorylation and isometric tension.

5 Ca(2+)] producing from 15% to 90% of maximal isometric tension.

6 perivascular nerves, and (iii) recording of isometric tension.

7 spended in organ chambers for measurement of isometric tension.

8 hat the ring operates close to conditions of isometric tension.

9 its activity and limiting the development of isometric tension.

10 ascular reactivity was examined by recording isometric tension.

11 to force imbalance and specifically loss of isometric tension.

12 ogenous troponin C, resulting in the loss of isometric tension.

13 Histamine did not increase isometric tension.

14 -response curves were constructed to measure isometric tension after administration of terbutaline (c

15 ating Ca(2+) levels, there is a reduction in isometric tension and ATPase rate.

16 The effect of temperature on isometric tension and cross-bridge kinetics was studied

17 ng the free energy driving the production of isometric tension and mechanical work.

18 ess fibers in cultured cells typically exert isometric tension and present little kinetic activity.

19 t for the inverse effect of Ca(2+) levels on isometric tension and rate of force redevelopment (k(TR)

20 ntracellular cAMP regulates endothelial cell isometric tension and RLC phosphorylation through inhibi

21 le to simulate the temperature dependence of isometric tension and shortening velocity.

22 In all four reconstituted muscle groups, isometric tension and stiffness increased linearly with

23 In Delta23Tm, both isometric tension and stiffness were about 40 % of the c

24 ons did not significantly affect the maximal isometric tension and the rates of force activation (kAC

25 mental data on the temperature dependence of isometric tension and the relationship between force and

26 pecifically alters the Ca(2+) sensitivity of isometric tension and the time course of relaxation in c

27 rgy available to generate force by measuring isometric tension, as the free energy of the states that

28 ith temperature in the range 5-40 degrees C: isometric tension at 10 and 30 degrees C was 0.65 and 1.

29 rature effect on isometric tension was less: isometric tension at 10 and 30 degrees C was 0.96 and 1.

30 nd dephosphorylated muscles develop the same isometric tension at full Ca(2+) saturation.

31 zed by a nearly 15% reduction in myofilament isometric tension at submaximum Ca2+ levels in the physi

32 hain (RLC) phosphorylation and a 35% drop in isometric tension, but it did not inhibit thrombin-stimu

33 osphorylation and only a minimal decrease in isometric tension, but it prevented thrombin-induced inc

34 tice spacing influences the SL dependence of isometric tension by reducing the probability of strong

35 e Ca2+ sensitivity of ATPase activity and of isometric tension by up to 0.15 pCa units.

36 Further, isometric tension-calcium relations in failing and norma

37 uman dilated cardiomyopathies, we determined isometric tension-calcium relations in permeabilized myo

38 Maximal active isometric tension curve and developed isometric force we

39 ll vessel wire myography was used to measure isometric tension developed by intact PA.

40 We also reproduce isometric tension development across mouse, rat and huma

41 We simultaneously determined isometric tension development and actomyosin Mg-ATPase a

42 On the other hand, it impairs isometric tension development and ATPase rate.

43 amily of GTPase-dependent kinases, regulates isometric tension development and myosin II RLC phosphor

44 Although lower stiffness and isometric tension development may indicate flash-freezin

45 endothelial cell basal and thrombin-induced isometric tension development.

46 induced increases in RLC phosphorylation and isometric tension development.

47 recorded together with a transmural ECG and isometric tension development.

48 ractility, including the Ca2+ sensitivity of isometric tension development.

49 Accordingly, isometric tension did not differ between patients and co

50 arteries were mounted on a wire myograph for isometric tension experiments.

51 tension-generating ability, i.e. the maximal isometric tension/fibre cross-sectional area (P0/CSA), w

52 disruptions are detected as local release of isometric tension/force unloading, which is directly cou

53 st that the increased calcium sensitivity of isometric tension in DCM may be due at least in part to

54 ein), receptor binding, cAMP production, and isometric tension in rings of ductus taken from immature

55 ges were not accounted for by the absence of isometric tension in the cells.

56 al colon) were prepared to record changes in isometric tensions in response to different agents and n

57 In control bovine myocardium, isometric tension increased linearly with temperature in

58 oteins augment the temperature dependence of isometric tension, indicating that the regulatory protei

59 ene sulphonamide (a myosin inhibitor), while isometric tension is reduced to approximately 15%, and t

60 mechanics to demonstrate that a reduction in isometric tension is sufficient to impair force transmis

61 In a control group, the muscle isometric tension measured in the extensor digitorum lon

62 Thrombin also increased isometric tension, ML-7, an inhibitor of myosin light ch

63 Actin-myosin contraction was measured as isometric tension of cultured monolayers grown on a coll

64 Addition of MgADP to the bath increased isometric tension over a wide range of [Ca(2+)] in skinn

65 y donors to determine control parameters for isometric tension (P(o)) development and Ca(2+) sensitiv

66 etric tension to 0.08 +/- 0.01 times control isometric tension (P0), but only reduced PC to 0.82 +/-

67 The normalized isometric tension-pCa relation was similar in HTN and co

68 Previous studies have shown that isometric tension (Po) decreases linearly in the logarit

69 nsatory increases in longitudinal stiffness, isometric tension, power and actomyosin interaction in a

70 The presence of isometric tension (prestress) at all levels of these mul

71 ch but temporarily exceeded the steady-state isometric tension reaching a maximum value approximately

72 Isometric tension recording demonstrated augmented maxim

73 ted by (1) immunohistochemical staining, (2) isometric tension recording, and (3) cGMP radioimmunoass

74 e determined using isolated tissue baths and isometric tension recording.

75 removed and suspended in separate baths for isometric tension recording.

76 nary arteries were mounted in a myograph for isometric tension recording.

77 ded in Krebs-Ringer bicarbonate solution for isometric tension recording.

78 The rings were suspended for isometric tension recording.

79 shortening velocity and also the kinetics of isometric tension redevelopment; these effects were unre

80 Isometric tension responses to rapid temperature jumps (

81 Isometric tension, stiffness and the cross-bridge kineti

82 In isometric tension studies of non-pregnant myometrium, th

83 rteries from Ossabaw swine were isolated for isometric tension studies.

84 ation of RhoA that regulates the decrease in isometric tension through a pathway involving cofilin.

85 The addition of 3 mM vanadate reduced isometric tension to 0.08 +/- 0.01 times control isometr

86 tivation, and cells undergoing a change from isometric tension to mechanical unloading were associate

87 a 0.5 mM MgADP jump initiated an increase in isometric tension under all conditions examined, even at

88 size or single fibre cross-sectional area or isometric tension.Unexpectedly, training reduced the myo

89 With 2Ac, isometric tension was 10% of the initial tension; with 3

90 on was 10% of the initial tension; with 3Ac, isometric tension was 23%; and with 4Ac, isometric tensi

91 Ac, isometric tension was 23%; and with 4Ac, isometric tension was 44%.

92 With MAc, isometric tension was 77% of the initial tension owing t

93 At pCa 6 (submaximal activation), strip isometric tension was approximately 3 times higher than

94 However, the calcium sensitivity of isometric tension was increased in DCM compared to nonfa

95 gulatory proteins, the temperature effect on isometric tension was less: isometric tension at 10 and

96 Isometric tension was measured and sinusoidal length per

97 ed to acetylcholine in increasing doses, and isometric tension was recorded.

98 Isometric tension was similar among the fibre types and

99 In skinned myocardial strips, maximum isometric tension was similar in t/t(PTU) (18.7+/-2.1 mN

100 ed in organ baths containing Krebs solution; isometric tension was then measured.

101 ress fibers, indicating that they were under isometric tension, whereas stress fibers were absent fro

102 rtment of a Perspex chamber for recording of isometric tension while the nodose ganglion and attached

103 The effect of temperature on isometric tension with and without the regulatory protei

104 An increase of isometric tension with temperature is accounted for by t

105 1vDelta5-14 mice exhibited decreased maximum isometric tension without a change in calcium sensitivit