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1 thway for conversion of acetyl coenzyme A to isopentenyl diphosphate.
2 endent reactions which convert mevalonate to isopentenyl diphosphate.
3 nthesis of the central isoprenoid precursor, isopentenyl diphosphate.
4 e last step of this biosynthetic sequence to isopentenyl diphosphate.
5 sphorylate isopentenyl phosphate, generating isopentenyl diphosphate.
6 ate (MEP, 5) pathway for the biosynthesis of isopentenyl diphosphate (1) and dimethylallyl diphosphat
7 f 7-8, and K(m) values of 124 micrometer for isopentenyl diphosphate, 38 micrometer for geranyl dipho
8 cteria, green algae, and plant chloroplasts, isopentenyl diphosphate, a key intermediate in the biosy
9 on of the two isoprenoid universal C5 units, isopentenyl diphosphate and dimethylally diphosphate, to
10 iene synthesis, we amplified the flux toward isopentenyl diphosphate and dimethylallyl diphosphate pr
11 thetic origin in the initial condensation of isopentenyl diphosphate and dimethylallyl diphosphate to
12 synthase (FDPS) catalyzes the conversion of isopentenyl diphosphate and dimethylallyl diphosphate to
13 hly dependent on the ratio of the substrates isopentenyl diphosphate and dimethylallyl diphosphate us
14 I-2), which catalyzes the interconversion of isopentenyl diphosphate and dimethylallyl diphosphate, c
16 hways operate in plants for the synthesis of isopentenyl diphosphate and dimethylallyl diphosphate, t
17 alloenzyme that catalyzes interconversion of isopentenyl diphosphate and dimethylallyl diphosphate, w
18 esis of their two universal building blocks, isopentenyl diphosphate and dimethylallyl diphosphate, w
19 he biosynthesis of the isoprenoid precursors isopentenyl diphosphate and dimethylallyl diphosphate.
20 ene geranyl diphosphate, when incubated with isopentenyl diphosphate and dimethylallyl diphosphate.
21 ate on the mevalonate-independent pathway to isopentenyl diphosphate and dimethylallyl diphosphate.
22 sis of the universal terpene building blocks isopentenyl diphosphate and dimethylallyl diphosphate.
23 oducing the essential isoprenoid precursors, isopentenyl diphosphate and dimethylallyl diphosphate.
24 l diphosphate (HMBPP) into the two products, isopentenyl diphosphate and dimethylallyl diphosphate.
25 s the synthesis of farnesyl diphosphate from isopentenyl diphosphate and dimethylallyl diphosphate.
26 ducing the universal precursors of terpenes: isopentenyl diphosphate and dimethylallyl diphosphate.
27 yzes the formation of neryl diphosphate from isopentenyl diphosphate and dimethylallyl diphosphate.
29 early pathway genes known to be involved in isopentenyl diphosphate and farnesyl diphosphate biosynt
30 se enzymes represented upstream pathways for isopentenyl diphosphate and geranylgeranyl diphosphate s
31 cript levels of paralogs encoding isoprenoid isopentenyl diphosphate and geranylgeranyl diphosphate-p
32 ylerythritol phosphate pathway to synthesize isopentenyl diphosphate and its allyl isomer dimethylall
33 renoids are constructed from two precursors, isopentenyl diphosphate and its isomer dimethylallyl dip
34 phosphate (MEP) pathway for biosynthesis of isopentenyl diphosphate and its isomer, dimethylallyl di
35 the conversion of radiolabeled mevalonate to isopentenyl diphosphate and other downstream products, i
37 hiolo-dimethylallyl diphosphate and S-thiolo-isopentenyl diphosphate bind intact to S2, but are cleav
38 coding enzymes of the mevalonate pathway for isopentenyl diphosphate biosynthesis in the gram-positiv
39 committed step in the mevalonate-independent isopentenyl diphosphate biosynthetic pathway and is a po
40 e mevalonate-independent pathway is the sole isopentenyl diphosphate biosynthetic pathway in this org
41 structures of Rv2361c in the apo form, with isopentenyl diphosphate bound and with a substrate analo
44 nzymes farnesyl diphosphate synthase (FPPS), isopentenyl diphosphate/dimethylallyl diphosphate isomer
47 DP-galactopyranose mutase (UGM), and type II isopentenyl diphosphate:dimethylallyl diphosphate isomer
48 hydrogens of a vinyl thiomethyl analogue of isopentenyl diphosphate exchanged with solvent when the
49 wever, based on in vivo feeding experiments, isopentenyl diphosphate formation in several eubacteria,
50 l three enzymes responsible for synthesis of isopentenyl diphosphate from mevalonate (mevalonate kina
51 hosphate (FPP) synthase (geranyl-diphosphate:isopentenyl-diphosphate geranyltranstransferase, EC 2.5.
52 e (MEP) pathway leads to the biosynthesis of isopentenyl diphosphate (IDP) and dimethylallyl diphosph
53 They are derived from the 5C building blocks isopentenyl diphosphate (IDP) and its isomer dimethylall
54 oducts dimethylallyl diphosphate (DMADP) and isopentenyl diphosphate (IDP) was postulated, but the ex
56 for metabolism of mevalonate 5-phosphate to isopentenyl diphosphate in Haloferax volcanii, two open
57 and co-locate with the homoallylic substrate isopentenyl diphosphate in other prenyltransferases.
59 s an isopentenyl phosphate kinase that forms isopentenyl diphosphate (in a reaction analogous to that
60 hosphate showed a 10-fold increase of [(14)C]isopentenyl diphosphate incorporation into decaprenyl di
61 phosphate showed a 5-fold increase of [(14)C]isopentenyl diphosphate incorporation into farnesyl diph
62 recombinant strains were assayed for [(14)C]isopentenyl diphosphate incorporation into isoprenyl dip
63 creased protein levels by 9-fold and reduced isopentenyl diphosphate (IPP) accumulation by 4-fold.
64 l 2-phosphate (MEP) pathway for synthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosph
65 equential chain elongation reactions between isopentenyl diphosphate (IPP) and dimethylallyl diphosph
66 point at which the pathway branches to form isopentenyl diphosphate (IPP) and dimethylallyl diphosph
67 e isomerase catalyzes the interconversion of isopentenyl diphosphate (IPP) and dimethylallyl diphosph
68 s D-glyceraldehyde phosphate and pyruvate to isopentenyl diphosphate (IPP) and dimethylallyl diphosph
69 (HMBPP) into the two isoprenoid precursors: isopentenyl diphosphate (IPP) and dimethylallyl diphosph
70 C(15) and C(20) isoprenoid diphosphates from isopentenyl diphosphate (IPP) and dimethylallyl diphosph
71 erase (IDI) catalyzes the interconversion of isopentenyl diphosphate (IPP) and dimethylallyl diphosph
73 erase (IDI) catalyzes the interconversion of isopentenyl diphosphate (IPP) and dimethylallyl diphosph
75 erase (IDI) catalyzes the interconversion of isopentenyl diphosphate (IPP) and dimethylallyl diphosph
76 erase (IDI) catalyzes the interconversion of isopentenyl diphosphate (IPP) and dimethylallyl diphosph
77 ve-carbon building blocks of all terpenoids, isopentenyl diphosphate (IPP) and dimethylallyl diphosph
78 e synthesized from the isoprenoid precursors isopentenyl diphosphate (IPP) and dimethylallyl diphosph
80 ginate from the five-carbon building blocks, isopentenyl diphosphate (IPP) and its isomer dimethylall
82 ntenyl diphosphate isomerase (IDI) activates isopentenyl diphosphate (IPP) for polymerization by conv
83 ondensation of dimethylallyl diphosphate and isopentenyl diphosphate (IPP) in a reaction catalyzed by
84 sphate isomerase (IDI) catalyzed reaction of isopentenyl diphosphate (IPP) in D(2)O gives a 66% yield
85 actions of allylic diphosphate acceptor with isopentenyl diphosphate (IPP) in the cis (Z) configurati
86 osphates to the carbon-carbon double bond in isopentenyl diphosphate (IPP) in the primary building re
91 rase, catalyzes the addition of thousands of isopentenyl diphosphate (IPP) molecules to an allylic di
93 enoid farnesyl diphosphate (FPP) by coupling isopentenyl diphosphate (IPP) to dimethylallyl diphospha
94 (IDI) catalyzes the essential conversion of isopentenyl diphosphate (IPP) to dimethylallyl diphospha
97 lta2 T cells: pyrophosphomonoesters, such as isopentenyl diphosphate (IPP), nitrogen-containing bisph
98 ynthesized by the successive condensation of isopentenyl diphosphate (IPP), with farnesyl diphosphate
105 he consecutive head-to-tail condensations of isopentenyl diphosphate (IPP, C5) with dimethylallyl dip
106 ive pathway for carbon flux amplification to isopentenyl-diphosphate (IPP) and dimethylallyl-diphosph
107 d arenarone bound solely to the homoallylic (isopentenyl diphosphate, IPP) site, not to the allosteri
109 Biosynthesis of the isoprenoid precursor, isopentenyl diphosphate, is a critical function in all i
118 psis thaliana cDNAs (IPP1 and IPP2) encoding isopentenyl diphosphate isomerase (IPP isomerase) were i
122 ntly described the identification of a novel isopentenyl diphosphate isomerase, IDI2 in humans and mi
125 ne, orf177, is a member of a large family of isopentenyl diphosphate isomerases, while sequence homol
126 abolites via the condensation of geranyl- or isopentenyl-diphosphate moieties by geranyltranstransfer
127 respectively, the addition of two and three isopentenyl diphosphate molecules to dimethylallyl dipho
132 y the nonmevalonate pathway for synthesis of isopentenyl diphosphate, the monomer unit for isoprenoid
133 ting carbon flow from cytosolic or plastidic isopentenyl diphosphate through overexpression in either
134 ondensation of dimethylallyl diphosphate and isopentenyl diphosphate to form geranyl diphosphate.
136 ondensation of dimethylallyl diphosphate and isopentenyl diphosphate to geranyl diphosphate, the key
137 phosphate synthase catalyzed the addition of isopentenyl diphosphate to omega,E-geranyl diphosphate o
139 es, responsible for converting mevalonate to isopentenyl diphosphate under the control of an arabinos
142 product of mevalonate metabolism proximal to isopentenyl diphosphate was responsible for the suppress
143 ases catalyze the sequential condensation of isopentenyl diphosphate with allylic diphosphates to syn
144 ead-to-tail condensation of two molecules of isopentenyl diphosphate with dimethylallyl diphosphate.
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