ライフサイエンスコーパス: isoprenoid

1 ts and produces a large variety of essential isoprenoids.

2 mmon precursors for the synthesis of plastid isoprenoids.

3 tides functionalized with benzophenone-based isoprenoids.

4 hophylls, beta-carotene, and stored volatile isoprenoids.

5 tanes+alkylcyclohexanes > cyclic and acyclic isoprenoids.

6 anobacteria for photosynthetic production of isoprenoids.

7 pathway that produces cholesterol and other isoprenoids.

8 ADP), the precursors for isoprene and higher isoprenoids.

9 ox amino acid sequence with various modified isoprenoids.

10 n the synthesis of cholesterol and nonsterol isoprenoids.

11 idopsis thaliana mainly accumulating primary isoprenoids.

12 y limited pool of substrates based on linear isoprenoids.

13 mino acids, fatty acids, starch, and diverse isoprenoids.

14 is known in plants accumulating specialized isoprenoids.

15 me in synthesis of cholesterol and nonsterol isoprenoids.

16 thway for synthesizing cholesterol and other isoprenoids.

17 groups of photosynthesis-related plastidial isoprenoids.

18 file of sterols, ubiquinones, and plastidial isoprenoids.

19 is interrupted by a highly charged region at isoprenoids 4-7.

20 ibe the development and application of a new isoprenoid analogue containing a diazirine moiety that w

21 imer and efficiently oxidizes C(10) to C(15) isoprenoid and aliphatic alcohols, showing the highest a

22 k expression patterns of nine genes from the isoprenoid and carotenoid biosynthetic pathways were mon

23 mgcs1, which encodes an enzyme necessary for isoprenoid and cholesterol synthesis, causes oligodendro

24 ome of approximately 30 PG core proteins and isoprenoid and neutral lipids.

25 unction and reveal important clues about how isoprenoid and sterol metabolism is integrated within pl

26 hese BChls were esterified with a variety of isoprenoid and straight-chain alkyl alcohols as in FAPs.

27 ified, including the cytosolic and plastidic isoprenoid and the phenylpropanoid pathways.

28 phosphate (MEcPP), a precursor of plastidial isoprenoids and a stress-specific retrograde signaling m

29 Isoprenoids and prenylated proteins have been implicated

30 rescue experiments, we provide evidence that isoprenoids and protein prenylation, but not cholesterol

31 hase (hFPPS) is the gate-keeper of mammalian isoprenoids and the key target of bisphosphonate drugs.

32 it may also play a role in the catabolism of isoprenoids and the mevalonate shunt.

33 ts on bioactive compound content (phenolics, isoprenoids), antioxidant capacity, in vitro biological

34 Isoprenoids are a class of natural products with more th

35 All isoprenoids are constructed from two precursors, isopent

36 Isoprenoids are diverse compounds that have their biosyn

37 Isoprenoids are diverse natural compounds, which have va

38 te immunity within the endometrium, and that isoprenoids are regulatory molecules in this process, kn

39 d (MVA) pathway from which sterols and other isoprenoids are synthesized.

40 terol levels, particularly by the mevalonate-isoprenoid arm of the sterol pathway.

41 cerevisiae for industrial production of the isoprenoid artemisinic acid for use in antimalarial trea

42 tty acids and cholesterol and is involved in isoprenoid-based protein modifications.

43 The isoprenoid benzoquinone conjugates plastoquinone and ubi

44 ansferase fold with hydrophobic residues for isoprenoid binding and a second binding pocket suitable

45 ms largely hydrophobic interactions with the isoprenoid binding site of RabGGTase and that it attache

46 cretion of intracellularly synthesized model isoprenoid biofuel compounds to the extracellular milieu

47 iting enzyme of the nonmevalonate pathway of isoprenoid biosynthesis (MEP pathway), is a clinically v

48 egulatory role in the mevalonate pathway for isoprenoid biosynthesis and is composed of an endoplasmi

49 of the methylerythritol phosphate pathway of isoprenoid biosynthesis are attractive anti-infective dr

50 al role that the mevalonate pathway plays in isoprenoid biosynthesis by these archaea.

51 gest a possible basis for the requirement of isoprenoid biosynthesis for the activity of plant miRNAs

52 and ORF4) exhibit significant identity with isoprenoid biosynthesis genes of Bacteria and Archaea.

53 Fe4S4] cluster-containing enzyme involved in isoprenoid biosynthesis in many bacteria as well as in m

54 ) pathway supplies precursors for plastidial isoprenoid biosynthesis including carotenoids, redox cof

55 -d-erythrithol-4-phosphate (MEP) pathway for isoprenoid biosynthesis offers interesting prospects for

56 phiphiles tested positive, and some targeted isoprenoid biosynthesis or affected lipid bilayer struct

57 otein IspH in the methylerythritol phosphate isoprenoid biosynthesis pathway is an important anti-inf

58 final step of the methylerythritol phosphate isoprenoid biosynthesis pathway is catalysed by the iron

59 ssess both the mevalonate and non-mevalonate isoprenoid biosynthesis pathways that produce metabolic

60 Furthermore, isoprenoid biosynthesis shows a characteristic species d

61 ctoisomerase), a key enzyme in nonmevalonate isoprenoid biosynthesis that is essential in Plasmodium

62 Isoprenoid biosynthesis through the methylerythritol pho

63 or the methylerythritol phosphate pathway of isoprenoid biosynthesis, and find evidence of sexual rep

64 hosphate (DXP), a branch point metabolite in isoprenoid biosynthesis, and is also used in the biosynt

65 ic fever disease characterized by a block in isoprenoid biosynthesis, are poorly understood.

66 methylerythritol phosphate (MEP) pathway of isoprenoid biosynthesis, including the clinically valida

67 ncluding chlorophyll degradation/senescence, isoprenoid biosynthesis, plastid proteolysis, and redox

68 on revealed an ancient dependency on plastid isoprenoid biosynthesis, predating the divergence of api

69 ae uses a chemically inefficient pathway for isoprenoid biosynthesis, resulting in yield and producti

70 nthesis, amino acid synthesis, flavonoid and isoprenoid biosynthesis, signaling and homeostasis, and

71 eparated pathways provide the precursors for isoprenoid biosynthesis.

72 A reductase (HMGR) activity, a key player in isoprenoid biosynthesis.

73 organelle involved in fatty acid, heme, and isoprenoid biosynthesis.

74 ting their role in developmentally regulated isoprenoid biosynthesis.

75 Both genes encode enzymes involved in isoprenoid biosynthesis.

76 IspG is a 4Fe4S protein involved in isoprenoid biosynthesis.

77 t carries out an essential reduction step in isoprenoid biosynthesis.

78 t carries out an essential reduction step in isoprenoid biosynthesis.

79 rrot taproot and is coexpressed with several isoprenoid biosynthetic genes.

80 recent years are the elucidation of a second isoprenoid biosynthetic pathway [the methylerythritol ph

81 Tanaka et al. show that reengineering of the isoprenoid biosynthetic pathway in E. coli (to bypass th

82 rnesyl pyrophosphate (FPP) production in the isoprenoid biosynthetic pathway in Escherichia coli.

83 Enzymes of the isoprenoid biosynthetic pathway in halophilic archaea re

84 an anti-infective target, as this essential isoprenoid biosynthetic pathway is widespread in human p

85 or the cytosol-localized, mevalonate-derived isoprenoid biosynthetic pathway.

86 ions in the methylerythritol phosphate (MEP) isoprenoid biosynthetic pathway.

87 PP) in the primary building reactions in the isoprenoid biosynthetic pathway.

88 ic inhibitors of the plastidic and cytosolic isoprenoid biosynthetic pathways, we demonstrated that t

89 Two of the most important discoveries in isoprenoid biosynthetic studies in recent years are the

90 tify an essential function of the mevalonate-isoprenoid branch of sterol biosynthesis during infectio

91 cessary to furnish the universal five-carbon isoprenoid building block, isopentenyl diphosphate (IPP)

92 isoprenylation from endogenously synthesized isoprenoids but enhances the use of exogenous isoprenols

93 are the building blocks for construction of isoprenoid carbon skeletons in nature.

94 The chain lengths of isoprenoid carbon skeletons vary widely from neryl pyrop

95 plex I catalysis with ubiquinones of varying isoprenoid chain length, from 1 to 10 units.

96 yl chain occupying the cavity that binds the isoprenoid chain of the substrate.

97 ng experiments facilitated assignments of UQ isoprenoid chain resonances not previously observed and

98 mmodate almost all of its approximately 50-A isoprenoid chain.

99 Archaea use isoprenoid chains linked via ether bonds to sn-glycerol

100 omics of macrophages with an improved alkyne-isoprenoid chemical reporter enables large-scale profili

101 These studies demonstrate the utility of isoprenoid chemical reporters for proteomic analysis of

102 -CO2 stresses emit large amounts of volatile isoprenoids compared with those in stress-free condition

103 required to initiate the biosynthesis of all isoprenoid compounds found in nature.

104 The biosynthetic pathways to isoprenoid compounds involve transfer of the prenyl moie

105 te (DMAPP), the essential building blocks of isoprenoid compounds, from mevalonate (MVA).

106 Isoprenoids consist of a large class of compounds that a

107 Isoprenoids constitute one of the most diverse classes o

108 An isoprenoid-containing chloroform extract of tomato fruit

109 arvae suggests flux control into C10 vs. C15 isoprenoids could be accomplished by these ions in vivo.

110 ocyanin, quercetin, kaempferol) and selected isoprenoid derivatives (chlorophyll, carotenoids) in the

111 Many isoprenoid derivatives are indispensable structural and

112 extract of tomato fruit and most individual isoprenoids did not induce electrophile-responsive eleme

113 nd suggest that PDP1/PPAPDC2 is a functional isoprenoid diphosphate phosphatase.

114 can generate as much as 50% of the cellular isoprenoid diphosphate pool used for protein isoprenylat

115 lls can use exogenous isoprenols to generate isoprenoid diphosphate substrates for protein isoprenyla

116 nsferase discovered that modifies an acyclic isoprenoid diphosphate, geranyl diphosphate (GPP), to yi

117 isoprenols containing an aniline group into isoprenoid diphosphates and protein isoprenylcysteines b

118 trans-prenyl transferases that produce trans-isoprenoid diphosphates from C(5) precursors; the epsilo

119 se (TgFPPS) that synthesizes C(15) and C(20) isoprenoid diphosphates from isopentenyl diphosphate (IP

120 athway for interconversion of isoprenols and isoprenoid diphosphates in intact mammalian cells and de

121 cis-prenyl transferases that produce the cis-isoprenoid diphosphates involved in bacterial cell wall

122 tenoid biosynthesis: the condensation of two isoprenoid diphosphates to form cyclopropylcarbinyl diph

123 ddition of the hydrocarbon moiety of allylic isoprenoid diphosphates to the carbon-carbon double bond

124 Small isoprenoid diphosphates, such as (E)-4-hydroxy-3-methyl-

125 -prenylating enzyme PagF, in complex with an isoprenoid donor analog and a panel of linear and macroc

126 The isoprenoid donor for protein geranylgeranylation reactio

127 , significantly correlated with constitutive isoprenoid emission rates across gradients of drought (r

128 of moderate abiotic stress levels, increased isoprenoid emission rates compete with photorespiration

129 carbon assimilation determines constitutive isoprenoid emission rates in plants and potentially even

130 mated energy pools and constitutive volatile isoprenoid emission rates in two species of eucalypts: E

131 Isoprenoid emission rates were insensitive to mild droug

132 TR-NAR ratio increased, driving constitutive isoprenoid emission until severe drought caused carbon l

133 ts of low-CO2, heat, and drought stresses on isoprenoid emission.

134 differential response of photosynthesis and isoprenoid emissions to progressing drought conditions.

135 erexpression led to only modest increases in isoprenoid end products and in the photosynthetic rate.

136 gulatory enzyme that controls the amounts of isoprenoid end products.

137 ol 4-phosphate pathway for the production of isoprenoids essential for photosynthesis and plant growt

138 hway, catalyzes the biosynthesis of the C-15 isoprenoid farnesyl pyrophosphate (FPP).

139 ar lipids connecting taurine via an amide to isoprenoid fatty acid conjugate of varying composition.

140 l maximum approximately a month earlier than isoprenoid fluxes, which highlights the differential res

141 yses have revealed intricate interactions in isoprenoid formation in the plastid that can be extrapol

142 By inhibiting the mevalonate pathway and isoprenoid formation, statins account for the increase o

143 at the MEP pathway, in addition to producing isoprenoids, functions as a stress sensor and a coordina

144 ow modulation of the concomitant activity of isoprenoid-generating pathways in plant cells; additiona

145 iated degradation augmented by the nonsterol isoprenoid geranylgeraniol through an unknown mechanism.

146 ein (VCP)/p97 and augmented by the nonsterol isoprenoid geranylgeraniol.

147 act cells, and is augmented by the nonsterol isoprenoid geranylgeraniol.

148 Supply of the isoprenoid geranylgeranyl pyrophosphate to oAbeta(42)-tr

149 In this process, an isoprenoid group is attached to a cysteine near the C te

150 through covalently linked fatty acids and/or isoprenoid groups play crucial roles in all forms of lif

151 Microbial production of isoprenoids has been considered as a promising approach

152 Non-stop carbocationic polycyclizations of isoprenoids have been called the most complex chemical r

153 ects on atmospheric chemistry, whereas other isoprenoids have diverse roles ranging from various biol

154 Because many isoprenoids have important biological activities, the ne

155 presence of a di-unsaturated highly branched isoprenoid (HBI) lipid biomarker (diene II) in Southern

156 e form of biosynthetic hybrids called hybrid isoprenoids (HIs).

157 Isoprenoids (i.e., farnesyl or geranylgeranyl groups) ar

158 is saved carbon toward essential nonvolatile isoprenoids, i.e. beta-carotene and lutein, most probabl

159 o specialized enzymes to efficiently produce isoprenoids in extremely acidic environments.

160 The low yield of isoprenoids in plants makes them difficult for cost-effe

161 isms mediated by essential and non-essential isoprenoids in response to soil water availability and s

162 low the biosynthesis of the large variety of isoprenoids including both primary and specialized metab

163 d are hard to quantify because the degree of isoprenoid inhibition by statins correlates to some exte

164 Heptaprenyl diphosphate (C35 -PP) is an isoprenoid intermediate in the synthesis of both menaqui

165 A new genetic screen has identified an isoprenoid intermediate that accumulates in stressed pla

166 ent of metabolic cross talk, the exchange of isoprenoid intermediates between compartmentalized pathw

167 ls; additionally, it suggests an exchange of isoprenoid intermediates between plastids and peroxisome

168 Because statins inhibit the production of isoprenoid intermediates in the cholesterol biosynthetic

169 ng HMGR, but possibly targets an MEP-derived isoprenoid involved in the early steps of the elicitatio

170 roduction, and chemical synthesis of complex isoprenoids is impractical.

171 uctase ERAD such that synthesis of nonsterol isoprenoids is maintained in sterol-replete cells.

172 A wide diversity of isoprenoids is produced in different plant compartments.

173 citation energy, mediated by photoprotective isoprenoids, is an important defense mechanism against d

174 On the other hand, cholesterol, but not isoprenoids, is necessary both for axon ensheathment and

175 ate pathway is used to produce the precursor isoprenoid, isopentenyl 5-diphosphate.

176 inable production of a commercially valuable isoprenoid, limonene.

177 iB protein kinase-like family is involved in isoprenoid lipid biosynthesis and is implicated in human

178 ranslational modification whereby non-sterol isoprenoid lipid chains are added, thereby modifying the

179 oes not transport a glycosylated diphosphate isoprenoid lipid.

180 s (important for protein glycosylation), and isoprenoids (lipid moieties responsible for the membrane

181 ional modification by covalent attachment of isoprenoid lipids (prenylation) regulates the functions

182 relation of transgene expression levels with isoprenoid marker metabolites (gene-to-metabolite correl

183 We conclude that intraspecific variation in isoprenoid-mediated photoprotective mechanisms contribut

184 Elucidation of the isoprenoid metabolic pathways is indispensable for the r

185 Human Vgamma2Vdelta2 T cells monitor isoprenoid metabolism by recognizing (E)-4-hydroxy-3-met

186 ow that a variety of manipulations affecting isoprenoid metabolism lead to stimulation of Vgamma2Vdel

187 overies suggest that unforeseen variation in isoprenoid metabolism may be widespread in nature.

188 tion, genes involved in flavonoid synthesis, isoprenoid metabolism, and photosynthesis (dark reaction

189 aluation of the effect of S-carvone on plant isoprenoid metabolism.

190 C(5) building block biogenesis that precedes isoprenoid metabolism.

191 the quantification of all the well known CK isoprenoid metabolites in four different transgenic Arab

192 and in cancer immunotherapy by responding to isoprenoid metabolites, such as (E)-4-hydroxy-3-methyl-b

193 for the biosynthesis of the more than 55,000 isoprenoid metabolites.

194 in A. thaliana mainly producing housekeeping isoprenoid metabolites.

195 pathogens by monitoring prenyl pyrophosphate isoprenoid metabolites.

196 e additional pathways of purine, pyrimidine, isoprenoid, methionine, riboflavin, coenzyme A, and fola

197 ethering, tether length, and the presence of isoprenoid methyl groups on one or both lipid tails.

198 Untethered lipids with two isoprenoid methyl tails led to lower PH+/OH- values than

199 Treatment with the isoprenoid mevalonate pathway-intermediates, farnesyl di

200 Undecaprenol) LLOs, which are composed of an isoprenoid moiety and an oligosaccharide, linked by pyro

201 renylation with a geranylgeranyl or farnesyl isoprenoid moiety and subsequent trafficking to cellular

202 orientation, structure, and dynamics of the isoprenoid moiety and the oligosaccharide.

203 The isoprenoid moiety shows high flexibility inside the bila

204 Isoprenoid molecules are essential elements of plant met

205 P), the basic five-carbon building blocks of isoprenoid molecules.

206 Trichothecenes are isoprenoid mycotoxins produced in wheat infected with th

207 dent alterations are observed in amino acid, isoprenoid, nucleic acid, and vitamin biosynthesis, sugg

208 mediated by DNA anchored by solanesol, a C45 isoprenoid of sufficient length to span the bilayer.

209 rily constituted of the low molecular weight isoprenoids, particularly monoterpenes.

210 Plant sterols are synthesized via the isoprenoid pathway by cyclization of 2,3-oxidosqualene t

211 t of statins was found to be mediated by the isoprenoid pathway downstream of mevalonate (the interme

212 Unlike the ubiquitous isoprenoid pathway for the biosynthesis of respiratory q

213 In this study, we engineered a heterologous isoprenoid pathway in E. coli for the high-yield product

214 bisphosphonates are two distinct classes of isoprenoid pathway inhibitors targeting downstream enzym

215 are specifically activated by phosphorylated isoprenoid pathway metabolites called "phosphoagonists."

216 x molecules requires substrate flux from the isoprenoid pathway, enzymes involved in late biosyntheti

217 at strontium-substituted BG up-regulated the isoprenoid pathway, suggesting an influence on both ster

218 nt 2-C-methyl-D-erythritol 4-phosphate (MEP) isoprenoid pathway, unexpectedly down-regulated the bios

219 (DXP), an intermediate in the nonmevalonate isoprenoid pathway.

220 synthase, a key enzyme of the nonmevalonate isoprenoid pathway.

221 hritol 2-C-methyl-D: -erythritol 4-phosphate isoprenoid pathway.

222 to increase the supply of precursors for the isoprenoid pathways.

223 DMADP as precursors for different downstream isoprenoid pathways.

224 terpenes (Quercus ilex), or that do not emit isoprenoids (Paulownia imperialis).

225 membrane lipid phosphatases as regulators of isoprenoid phosphate metabolism and suggest that PDP1/PP

226 geranyl reductase (GGDR) which restricts the isoprenoid precursor availability.

227 riptional control at each individual step of isoprenoid precursor biosynthesis.

228 (STS)-mediated cyclization of the linear C25 isoprenoid precursor geranylfarnesyl diphosphate (GFPP)

229 valonate pathway for the biosynthesis of the isoprenoid precursor isopentenyl pyrophosphate, 1-deoxy-

230 Synthesis of IPP, an isoprenoid precursor molecule that is a critical interme

231 g that frontalin is derived from a 20-carbon isoprenoid precursor rather than from the 10- or 15-carb

232 lciparum treated with RCB-185 was rescued by isoprenoid precursor supplementation, and treatment subs

233 Isoprenoid precursor synthesis is the only essential rol

234 cetyl coenzyme A (acetyl-CoA, the two-carbon isoprenoid precursor) with a reduced ATP requirement, re

235 ral mechanism to control the biosynthesis of isoprenoid precursors in different plant cell compartmen

236 operating in parallel in plants to generate isoprenoid precursors, has been studied extensively.

237 in the MEP pathway, producing the essential isoprenoid precursors, isopentenyl diphosphate and dimet

238 pathway for the synthesis of their essential isoprenoid precursors.

239 hosphate (DOXP) pathway for the synthesis of isoprenoid precursors.

240 t-2-en-1-yl diphosphate (HMBPP) into the two isoprenoid precursors: isopentenyl diphosphate (IPP) and

241 tol cyclodiphosphate (MEcPP), a precursor of isoprenoids produced by the plastidial methylerythritol

242 emical entity serving as both a precursor of isoprenoids produced by the plastidial methylerythritol

243 lline GPPMT, followed by dissociation of the isoprenoid product.

244 mining the specificity and the length of the isoprenoid product.

245 The nonmevalonate pathway is responsible for isoprenoid production in microbes, including H. pylori,

246 To enhance isoprenoid production, computational strain design was c

247 rify FREP by evolving increased tyrosine and isoprenoid production.

248 a show a remarkable metabolic plasticity for isoprenoid production.

249 the MEP pathway and into the major plastidic isoprenoid products in isoprene-emitting and transgenic

250 In addition, isoprenoid secondary metabolites are highly valuable nat

251 occurring in C. roseus producing specialized isoprenoid secondary metabolites is somehow different fr

252 In studying the effects of isoprenoid shortage on IL-1 beta generation, we identifi

253 ental conditions needs to be ascertained but isoprenoids should not be neglected when considering ras

254 ase reaction in the recently discovered "MTA-isoprenoid shunt" that generates 1-deoxy-d-xylulose 5-ph

255 as the substrate, which demonstrates that an isoprenoid side chain enhances enzymatic hydroxylation a

256 for the synthesis of ubiquitous GGPP-derived isoprenoid species.

257 nality assist product dissociation, and that isoprenoid stepping ensures short transit times.

258 Isoprenoid-substituted bisphosphonates are known to serv

259 A class II cyclase activates the isoprenoid substrate by protonation instead of ionizatio

260 brevifolia) is the cyclization of the linear isoprenoid substrate geranylgeranyl diphosphate (GGPP) t

261 turally occurring, noncanonical C-methylated isoprenoid substrate, 2-methylgeranyl diphosphate, to fo

262 ting these strains for biosynthesis of other isoprenoids such as beta-farnesene (C15H24), a plant ses

263 hway that produces cholesterol and nonsterol isoprenoids such as GGpp.

264 Many important plant isoprenoids, such as chlorophylls, carotenoids, tocopher

265 alyzes the synthesis of sterol and nonsterol isoprenoids, such as cholesterol and ubiquinone, as well

266 acids of the resin and no change in primary isoprenoids, such as sterols, chlorophylls, and caroteno

267 excellent coverage for fatty acid synthesis, isoprenoid, sulfur, nitrogen, and amino acid metabolism,

268 recessive mutations in a novel gene, called isoprenoid synthase domain containing (ISPD), are a rela

269 cessive mutations in the ISPD gene (encoding isoprenoid synthase domain containing).

270 plete polyprenyl transferase subgroup of the isoprenoid synthase superfamily computationally.

271 lyprenyl transferase (E-PTS) subgroup in the isoprenoid synthase superfamily, which provides substrat

272 sferase, haloalkanoic acid dehalogenase, and isoprenoid synthase), with five superfamily specific Bri

273 ation; and the observation that head-to-tail isoprenoid synthases as well as terpene cyclases have io

274 yl-D-erythritol 4-phosphate (MEP) pathway of isoprenoid synthesis by end products dimethylallyl dipho

275 We used Escherichia coli isoprenoid synthesis H (Protein Data Bank code 3F7T) as

276 ally reduced by either partial inhibition of isoprenoid synthesis pathway by fosmidomycin-feeding or

277 m is essential in Gram-positive bacteria for isoprenoid synthesis via the mevalonate pathway.

278 oreign prenyl pyrophosphate intermediates in isoprenoid synthesis.

279 eta-oxidation and the mevalonate pathway for isoprenoid synthesis.

280 the reductase ERAD pathway and regulation of isoprenoid synthesis.

281 C-methyl-d-erythritol 4-phosphate pathway of isoprenoid synthesis.

282 Most groups of isoprenoids synthesized in plastids, and some produced e

283 structural differences in chromanol head and isoprenoid tail, polarity, concentration, oxidation time

284 +/OH- values than lipids with only one or no isoprenoid tails.

285 ted gene loci, including several involved in isoprenoid/terpenoid metabolism.

286 Quinones are naturally occurring isoprenoids that are widely exploited by photosynthetic

287 osphate (GGPP) is a key precursor of various isoprenoids that have diverse functions in plant metabol

288 Carotenoids are isoprenoids that play essential roles in photosynthesis

289 Menaquinones (naphthoquinones, MK) are isoprenoids that play key roles in the respiratory elect

290 evalonate kinase causes limited synthesis of isoprenoids, the effects of which are widespread.

291 Bacteria, plants, and algae produce isoprenoids through the methylerythritol phosphate (MEP)

292 t-translational attachment of geranylgeranyl isoprenoids to Rab GTPases, the key organizers of intrac

293 These results suggest that the isoprenoid transition-state conformation is preferred ov

294 ed and monounsaturated menaquinones with six isoprenoid units forming the alkyl chain may serve as ch

295 IDI) catalyze the interconversion of the two isoprenoid universal C5 units, isopentenyl diphosphate a

296 Mevalonate (MVA) metabolism provides the isoprenoids used in archaeal lipid biosynthesis.

297 a geranylgeranyl diphosphate (GGPP)-derived isoprenoid, which are generated by the tetrapyrrole and

298 ke myelin, is not known nor is clear whether isoprenoids, which also are products of the cholesterol

299 hly conserved and mediates the production of isoprenoids, which feed into biosynthetic pathways for s

300 diphosphate (2), the universal precursors of isoprenoids, while humans exclusively utilize the altern