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1 (the latter against the TRPA1 agonist allyl isothiocyanate).
2 the well-established anticancer activity of isothiocyanate.
3 fic anti-TNT antibody labeled with rhodamine isothiocyanate.
4 enone, ethylene trithiocarbonate, and phenyl isothiocyanate.
5 teroallene functions, such as isocyanate and isothiocyanate.
6 e ITC carbon in (13)C NMR spectra of organic isothiocyanates.
7 e aglucones that rearrange to form defensive isothiocyanates.
8 olyzes them to form toxic compounds, such as isothiocyanates.
9 ange 20-30 kcal/mol for rearrangement to the isothiocyanates.
10 imilar in magnitude or direction for the two isothiocyanates.
11 , summing up to 20.7 +/- 1.7 mumol/g of free isothiocyanates.
12 in vivo bioavailability and the activity of isothiocyanates.
13 e highest with the lowest tertile of urinary isothiocyanates.
14 l, 4-(methylthio)butyl, benzyl and phenethyl isothiocyanates.
15 ya aroma, from which ethyl butanoate, benzyl isothiocyanate, 1-hexen-3-one, (E)-beta-ionone, and meth
17 syntheses of (-)-N-methylwelwitindolinone C isothiocyanate (2a), (-)-N-methylwelwitindolinone C ison
18 and (-)-3-hydroxy-N-methylwelwitindolinone C isothiocyanate (3a) from a common tetracyclic intermedia
19 stablished for test analytes malachite green isothiocyanate, 4-aminothiophenol, and Rhodamine 6G (Rh6
22 und that sulforaphane (4-methylsulfinylbutyl isothiocyanate), a natural product derived from aliphati
25 uced inhibition of DUBs may also explain how isothiocyanates affect inflammatory and DNA repair proce
27 imicrobial packaging incorporated with allyl isothiocyanate (AIT) and carbon nanotube (CNT), and this
29 (alpha-ZOL) on a solution model using allyl isothiocyanate (AITC) and also determines the bioaccessi
30 abbage that accounted for the enhanced allyl isothiocyanate (AITC) in the volatile oils of the irradi
35 activators, including cinnamaldehyde, allyl isothiocyanate (AITC), and 4-hydroxynonenal, increased [
37 ons while capsaicin (TRPV1 agonist) or allyl-isothiocyanate (AITC, TRPA1 agonist) elicited responses
39 easing doses of the chemical irritants allyl isothiocyanate (AITC; also known as mustard oil) or caps
41 Notably, TNPs were labeled with fluorescein isothiocyanate allowing particles and cells to be simult
43 abinoid receptors, namely, the electrophilic isothiocyanate AM994 and the photoactivatable aliphatic
44 Here we have demonstrated that several other isothiocyanate analogues bearing basic moieties can deri
48 hese substituents included the electrophilic isothiocyanate and photoactivatable azido groups, both o
49 action of alpha-lithiated alkoxyallenes with isothiocyanates and alkyl 2-bromoacetates has been disco
50 ergent reaction of 2-aminobenzimidazole with isothiocyanates and dihalomethanes has been developed fo
51 ocumulenes like carbodiimides, isocycanates, isothiocyanates and ketenimines as electrophiles and sub
52 apies based on potent electrophiles, such as isothiocyanates and Michael acceptors, that, far from be
53 ositive correlations between glucosinolates, isothiocyanates and sulfur compounds with bitterness, mu
54 olecules (CH3-PEG5K-FITC (FITC = fluorescein isothiocyanate) and eight-arm PEG20K-FITC) was at least
55 des) and of glucosinolate hydrolysis (mainly isothiocyanates), and their dynamics of formation after
56 bulin among benzyl isothiocyanate, phenethyl isothiocyanate, and sulforaphane correlate well with the
57 lyl thiocyanates, arylamino thiocyanates and isothiocyanates, and arylsulfenyl thiocyanates and isoth
59 1 and isoquinuclidene 2 add to isocyanates, isothiocyanates, and in situ-generated carbodiimides to
60 g a significant potentiating effect on allyl isothiocyanate- and diclofenac-induced currents of TRPA1
61 eled IAV in the presence of anti-fluorescein isothiocyanate antibody also resulted in viral protein s
63 d carbonyls, sulfhydryl reactive metals, and isothiocyanates are strong activators of Nrf2 in a repor
65 67 antibodies conjugated to fluorescein 5(6)-isothiocyanate, as a photoactivatable agent, followed by
66 with 4-mercaptobutyl and 4-(methylthio)butyl isothiocyanate, associated with typical rocket and radis
67 using a nanoparticle-glutathione-fluorescein isothiocyanate (AuNP-GSH-FITC) probe coupled with on-lin
68 -5 nM) containing either a bromoacetamide or isothiocyanate based on the mu opioid receptor (MOR) sel
69 These sax genes are required to overwhelm isothiocyanate-based defenses and facilitate a disease o
71 abundance of isothiocyanates such as benzyl isothiocyanate (BITC) and phenethyl isothiocyanate (PEIT
74 addition of glutathione mainly to phenethyl isothiocyanate, but alternatively and in a competitive w
75 ane analogs with replacement of the reactive isothiocyanate by the more gentle electrophilic sulfoxyt
76 coefficients of amines, amides, isocyanates, isothiocyanates, carbamates and thiocarbamates with OH r
80 Bcr-Abl, resulting in degradation under low isothiocyanate concentrations and aggregation under high
81 ely evaluate the association between urinary isothiocyanate concentrations and colorectal cancer risk
84 a, assessed after perfusion with fluorescein isothiocyanate-conjugated concanavalin A, was increased
85 ons of jejunum were stained with fluorescein isothiocyanate-conjugated isolectin-B4 for endothelium t
86 images of B cells infected with fluorescein isothiocyanate-conjugated JCV demonstrated that JCV ente
87 bon-sulfur lyase SUR1 in processing cysteine-isothiocyanate conjugates, as well as the S-methyltransf
88 For in vivo analyses, we used fluorescein isothiocyanate contact hypersensitivity and ovalbumin-in
89 3 time points were significantly different - isothiocyanate-containing molecules being abundant on 'D
94 different electrophiles (i.e., isocyanates, isothiocyanates, cyclic anhydrides, and acyl chlorides)
95 pecifically, concentrations of aldehydes and isothiocyanates decreased with time paralleling a fall i
96 ganic thiocyanates, can be formed instead of isothiocyanates depending on the glucosinolate side chai
98 ethylsulfinyl)butane], a naturally occurring isothiocyanate derived from cruciferous vegetables, is a
99 ly demonstrated that sulforaphane, a dietary isothiocyanate derived from its glucosinolate precursor
100 seful quality indicators for e.g. changes in isothiocyanates derived from nutritionally important glu
101 sothiocyanate and to l-sulforaphane (dietary isothiocyanates derived from watercress and broccoli, re
102 s, ileal mucosal permeability to fluorescein isothiocyanate dextran, bacterial counts in the mesenter
104 resistance, paracellular flux of fluorescein isothiocyanate-dextran 4 kDa, and mRNA expression of tig
105 measuring permeability to 4-kDa fluorescein isothiocyanate-dextran and by examining changes in expre
108 +/- 13.4 vs 59.6 +/- 10.1 mg/mL fluorescein isothiocyanate-dextran flux; P < .05) and impaired inter
110 lar permeability was assessed by fluorescein isothiocyanate-dextran passage in both lines and by tran
111 24 hours (as assessed by 70-kDa fluorescein isothiocyanate-dextran transmucosal flux); ii) occludin
112 permeability was investigated by fluorescein isothiocyanate-dextran uptake assay, quantitative RT-PCR
113 in paracellular permeability to fluorescence isothiocyanate-dextran, and altered apical side tight ju
114 cular blood flow was assessed by fluorescein isothiocyanate/dextran angiography, with fluorescent ima
115 extent of vascular filling with fluorescein isothiocyanate/dextran) was significantly decreased in p
116 Daratumumab was conjugated to DFO-p-benzyl-isothiocyanate (DFO-Bz-NCS) for radiolabeling with (89)Z
118 agnetic nanoparticles containing rhodamine B isothiocyanate dye (MNPs@SiO2(RITC)) in HEK293 cells, SH
119 0) = 34 microM) than the TRPA1 agonist allyl isothiocyanate (EC(50) = 400 microM) or the TRPV3 agonis
120 nation with the ROS inducer beta-phenylethyl isothiocyanate efficiently inhibits the growth of breast
122 their free isothiocyanate forms, fluorescein isothiocyanate (F-ITC) and tetramethylrhodamine isothioc
123 ein infusion of (125)I-fibrin or fluorescein isothiocyanate-fibrin labeled emboli in anesthetized mic
126 ablished using the high affinity fluorescein isothiocyanate (FITC) containing peptide, FITC-NH-(CH2)4
127 of SAENTA and SAHENTA with fluorescein-5-yl isothiocyanate (FITC) gave fluorescent probes that bound
129 entification by imaging a 20 muM fluorescein isothiocyanate (FITC) labelling solution on mammalian ti
130 ng signaling probes labeled with fluorescein isothiocyanate (FITC) or digoxigenin (Dig), followed by
134 rm) was selectively labeled with fluorescein isothiocyanate (FITC), a probe that specifically reacts
135 hree commonly used fluorophores (fluorescein isothiocyanate (FITC), tetramethylrhodamine isothiocyana
136 th a fluorescent contrast agent, fluorescein isothiocyanate (FITC), we aimed to explore the potential
137 n constant (Kd) of Man-SNPs with fluorescein isothiocyanate (FITC)-concanavalin A (Con A) was determi
138 tance (TEER) and permeability to fluorescein isothiocyanate (FITC)-conjugated dextran, and (ii) AJC s
140 TB (DSS+ATB) was demonstrated by fluorescein isothiocyanate (FITC)-dextran translocation to the circu
143 trical resistance, and increased fluorescein isothiocyanate (FITC)-inulin diffusion across the polari
144 ) (PEDOT)/Pt-Ni microengines and fluorescein isothiocyanate (FITC)-labeled avidin (Av-FITC) as the te
147 online with Cy5-labeled insulin, fluorescein isothiocyanate (FITC)-labeled IAPP, anti-insulin, and an
149 ce (TEER) analysis, diffusion of fluorescein isothiocyanate (FITC)-labeled markers, and immunostainin
151 que, diffusion coefficients D of fluorescein isothiocyanate (FITC)-pepsin were measured in rennet gel
155 or the visible range [containing fluorescein isothiocyanate (FITC)], by utilizing a difluoromethylphe
158 rimers (G5), functionalized with fluorescein isothiocyanate (FL) and alphaVbeta3-specific, cyclic arg
159 energy transfer occurring from a fluorescein isothiocyanate fluorescent dye to plasmonic citrate-capp
160 spectroscopy and bear a tetramethylrhodamine isothiocyanate fluorescent tag for excitation at 532 nm.
161 nsisting of folate conjugated to fluorescein isothiocyanate (folate-FITC) can redirect and regulate F
162 thioate, N-alkyl dithiocarbamate, and phenyl isothiocyanate, followed by intramolecular copper-cataly
164 also undertaken using the dyes in their free isothiocyanate forms, fluorescein isothiocyanate (F-ITC)
165 lforaphane (SFN) is a biologically important isothiocyanate found in cruciferous vegetables that is a
166 report that purified sulforaphane, a natural isothiocyanate found in cruciferous vegetables, has anti
167 Sulforaphane (SFN) is a naturally occurring isothiocyanate found in cruciferous vegetables, such as
168 (X), raphasatin (4-methylsulphanyl-3-butenyl isothiocyanates; G) and (-)-epigallocatechin-3-gallate (
172 ical amino acid (ncAA) that contains an aryl isothiocyanate group which can form stable thiourea cros
173 a photoactive azide moiety and a fluorescein isothiocyanate group, irreversibly labels sigma-2 recept
174 ethod, Urea Method, Salt Method, Guanidinium Isothiocyanate (GuSCN) Method, Wizard Method, Qiagen Met
175 of activated aziridines with aryl and alkyl isothiocyanates has been accomplished leading to the for
177 -diaza-1,3-dienes (DDs), primary amines, and isothiocyanates in a different sequential order of addit
178 released instead of the cancer preventative isothiocyanates in Brassica vegetables, such as cabbage,
180 s find pungent and irritating, such as allyl isothiocyanate (in wasabi) and acrolein (in cigarette sm
181 ion of aldehyde dehydrogenase with phenethyl isothiocyanate increased the inhibitory effect of ethano
185 yl isothiocyanate (PEITC), a natural dietary isothiocyanate, inhibits angiogenesis but the molecular
186 Analogously, aryl- and alkyl-substituted isothiocyanates instead of carbon disulfide afforded the
187 arabidopsidis and other plant pathogens, the isothiocyanate is promising for the development of a pla
192 hodamine isothiocyanate (TRITC), fluorescein isothiocyanate isomer I(FITC) and DNA molecules, forming
199 in animal models have indicated that dietary isothiocyanates (ITCs) exhibit cancer preventive activit
201 sica anticarcinogenic components, especially isothiocyanates (ITCs) that stimulate detoxification of
202 One class of cancer-preventive nutrients, isothiocyanates (ITCs), derived from the consumption of
206 (TRITC-AF) as a ST substrate and fluorescein isothiocyanate labeled 3-aminophenylboronic acid (FITC-A
208 Systemic administration of an fluorescein isothiocyanate-labeled (RXRRBR)(2)XB-AMO in mice showed
209 or fluorescence was 125 fmol for fluorescein isothiocyanate-labeled bovine serum albumin, and this le
210 nt level of gelatinolysis of the fluorescein isothiocyanate-labeled gelatin and exhibits an intrinsic
212 ivity (NPA) was determined using fluorescein isothiocyanate-labeled opsonized Escherichia coli and ox
213 were isolated and incubated with fluorescein isothiocyanate-labeled P. gingivalis, and phagocytosis w
214 croarray to analyze binding with fluorescein isothiocyanate-labeled PEMV; however, no specific bindin
215 ences are amplified by PCR using fluorescein isothiocyanate-labeled sense and biotin-labeled antisens
217 de (bovine insulin) and protein (fluorescein isothiocyanate-labelled bovine serum albumin (FTIC-BSA))
218 ayer, by a bridge constituted of rhodamine B isothiocyanate, leading to a fluorescent, magnetic driva
219 -antibody constructs linked through a benzyl isothiocyanate linkage were more favorable than those li
220 tion, and decreased migration of fluorescein isothiocyanate-loaded dendritic cells (DCs) to draining
224 es in which the Raman label (malachite green isothiocyanate, MGITC) molecules are sandwiched between
225 ponses triggered by the TRPA1 agonists allyl-isothiocyanate (mustard oil), carvacrol, and polyunsatur
228 roup formed by a reversible reaction between isothiocyanate of sulforaphane and sulfhydryl nucleophil
229 ates RX-YCN and the isomeric isocyanates and isothiocyanates of the type RX-NCY (X = CR(2), NR', O, o
231 g TRPV1(+) or TRPA1(+) neurons allowed allyl isothiocyanate or capsaicin, respectively, to evoke itch
232 responding quenching when activated by allyl isothiocyanate or heat suggest lipid bilayer-independent
233 of IQGAP1 significantly attenuated phenethyl isothiocyanate- or MEK-mediated activation of the MEK-ER
234 e cruciferous vegetable derivative phenethyl isothiocyanate (PEITC) can reduce risk of human cancers,
235 e show here that the dietary agent phenethyl isothiocyanate (PEITC) inhibits heat shock protein 90 (H
237 nsitive to cytotoxicity induced by phenethyl isothiocyanate (PEITC) than those with the wild-type pro
243 nding affinities toward tubulin among benzyl isothiocyanate, phenethyl isothiocyanate, and sulforapha
245 ng properties, as their hydrolysis products, isothiocyanates, possess chemopreventive and antioxidant
247 mined by co-immunoprecipitation, fluorescein isothiocyanate-probing, and surface plasmon resonance an
249 at sulforaphane (SFN), a naturally occurring isothiocyanate, promotes osteoblast differentiation by e
251 hat in Arabidopsis (Arabidopsisthaliana) the isothiocyanate provokes covalent modification (K4me3, K9
252 the specific binding capacity of fluorescein isothiocyanate-RamAb to VEGFR-2, and no difference in VE
253 yl thiocyanates RCO-SCN to the corresponding isothiocyanates RCO-NCS are 30-31 kcal/mol in agreement
256 h parigidin-br1 or parigidin-br1-fluorescein isothiocyanate, respectively, revealed extensive cell ly
258 oach is extended to a commercial Rhodamine B isothiocyanate (RITC) label, clearly revealing the probl
259 methods of the N terminus with 4-sulfophenyl-isothiocyanate (SPITC) or the C terminus with 2-methoxy-
260 solution via carbamylation and 4-sulfophenyl isothiocyanate (SPITC) provided evidence for sulfonate i
261 well known and attributed to an abundance of isothiocyanates such as benzyl isothiocyanate (BITC) and
262 e toxic and detrimental to animals, but some isothiocyanates such as sulforaphane are potent anti-car
264 l classes; alpha-beta unsaturated carbonyls, isothiocyanates, sulfhydryl reactive metals, flavones, a
265 r protein Keap1 by electrophiles such as the isothiocyanate sulforaphane can direct Nrf2 accumulation
268 s in lymphoid cells treated with the dietary isothiocyanate, sulforaphane (SFN) and carried out follo
269 was developed for the well-known anti-cancer isothiocyanates-sulforaphene (SE) and sulforaphane (SF).
270 ciceptive and inflammatory response to allyl isothiocyanate (the agonist of TRPA1) and reversed CFA (
271 othiocyanate-thioacyl isocyanate and imidoyl isothiocyanate-thioacyl carbodiimide rearrangements.
272 ched to the (thio)acyl groups, that is, acyl isothiocyanate-thioacyl isocyanate and imidoyl isothiocy
273 nvolved in the metabolism and elimination of isothiocyanates; thus, genetic variations in these enzym
274 cosinolate hydrolysis from the generation of isothiocyanates to that of epithionitriles or nitriles,
275 nding the function and useful application of isothiocyanates to treat cancer as well as a variety of
277 ed the decrease in Bcr-Abl levels induced by isothiocyanate treatment, and USP9x silencing was suffic
278 es increased Mcl-1 ubiquitination and either isothiocyanate treatment, or RNAi-mediated silencing of
279 isothiocyanate (FITC), tetramethylrhodamine isothiocyanate (TRITC), and carboxytetramethylrhodamine
280 uorescent dyes such as tetramethyl rhodamine isothiocyanate (TRITC), fluorescein isothiocyanate isome
281 uring mitosis, as confirmed with fluorescein isothiocyanate-uridine 5'-triphosphate labeling, RNA flu
282 e cyclization of 2-aminopyridine/amidine and isothiocyanate via N-S bond formation at ambient tempera
285 fluorocarbon combined with FITC (fluorescein isothiocyanate) was administered for postmortem immunofl
287 ween 1,3-dimesitylimidazolylidene and phenyl isothiocyanate were determined (H(o) = -96.1 kJ mol(-1)
289 ysates, together with five omega-phenylalkyl isothiocyanates were tested for their spasmolytic, cytot
290 nsive odorous compounds, particularly benzyl isothiocyanate, were removed from partially purified gly
291 rs (ca. 40 kcal/mol) toward rearrangement to isothiocyanates, whereas all thioacyl thiocyanate deriva
292 the large (>1 nm) negative dye fluorescein-5-isothiocyanate while decreasing entry of the structurall
293 reen emitting fluorophore, FITC (fluorescein isothiocyanate), whose luminescence is insensitive to Hg
296 atroposelectively by the reaction of o-aryl isothiocyanates with amino acid ester salts in the prese
300 d correlate structural features of these two isothiocyanates with their second-order rate constants f
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