ライフサイエンスコーパス: isotonic

1 , controlled trial of hypertonic (7%) versus isotonic (0.9%) saline inhaled twice daily for 48 weeks

2 Infusion of isotonic (0.9%) saline into the other leg served as cont

3 It was extracted from the AM by isotonic, 1 M NaCl, and 4 M guanidine HCl solutions, sug

4 In isotonic 140 mM KCl, the skeletal muscle NMCC exhibits a

5 artridge, washed with water, and eluted with isotonic 4% sodium citrate.

6 esulted in a chimeric KCC that was devoid of isotonic activity, with intact swelling-activated transp

7 are exclusively swelling-activated, with no isotonic activity.

8 collecting duct 3 (IMCD3) cells grown under isotonic and chronic hypertonic conditions.

9 stically significant increases in MCT in the isotonic and HS-P308 groups.

10 reduced NKCC1 activity in oocytes under both isotonic and hypertonic conditions to the same level as

11 s urea transporter-A reporter activity under isotonic and hypertonic conditions.

12 ry collecting duct (IMCD3) cells grown under isotonic and hypertonic conditions.

13 vessels was performed with filter-sterilized isotonic and hypertonic solutions that contained glucose

14 Both isotonic and hypertonic volume expansions reversed the c

15 he responses of cell cultures to significant isotonic and hypotonic challenges, and to hypertonic sal

16 Under isotonic and hypotonic conditions, Cl(-) channels displa

17 Clinical trial data comparing isotonic and hypotonic maintenance fluids in nonsurgical

18 nd with the vesicles followed by washes with isotonic and hypotonic solutions.

19 irect evidence that the ASL is approximately isotonic and not saltier in cystic fibrosis.

20 In contrast, isotonic and secretion-inducing (hypertonic) vehicles le

21 us messenger produced in this nucleus during isotonic and short-term hypertonic conditions, is an exa

22 here are exclusive molecular determinants of isotonic and swelling-induced K(+)-Cl(-) cotransport in

23 nd twitches under isometric, isosarcometric, isotonic, and auxotonic conditions.

24 calf after arterial occlusion and also after isotonic ankle exercise.

25 oted a decrease in TauT reporter activity in isotonic as well as hyperosmolar media.

26 in the appropriate voltage range (>0 mV, in isotonic Ba2+) and is blocked by omegaCGVIA.

27 ver, a channel that is active near -10 mV in isotonic Ba2+, originally identified as "N-type," corres

28 vement times also improved for isometric and isotonic ballistic movements.

29 ells were subsequently exposed for 15 min to isotonic buffer (122 mM NaCl) also containing 100 mM EtO

30 ina was removed by exposure of the eyecup to isotonic buffer and wherever required, the retinal pigme

31 To determine whether MeHg in isotonic buffer has the potential to interfere with home

32 solution of mannitol, and pre-infusion of an isotonic buffer solution followed by infusion of nanopar

33 ter Pt disk microelectrodes at the nuclei in isotonic buffer solutions containing redox-active molecu

34 In isotonic buffer the effect of MeHg on swelling was aboli

35 Rat liver was homogenized in isotonic buffer, fractionated by differential centrifuga

36 At 20 degrees C, in pH 7.5 isotonic buffer, the strongest MII-G(t) binding was obse

37 ture in 10 mM phosphate buffer compared with isotonic buffer.

38 ug nanocarriers at 2-3mg/mL concentration in isotonic buffers and serum.

39 cerol-Ringer solution, its replacement by an isotonic Ca(2+)-Mg(2+) Ringer solution and cooling sharp

40 In isotonic CaCl2 solution, the slope conductance of the ch

41 tudy, we illustrate how electroporation with isotonic calcium can achieve highly effective cancer cel

42 Fibres in isotonic Cl(-)-free, normal and Na(+)-free Ringer soluti

43 hemoglobin HbC or HbS+ gamma, replacement of isotonic Cl- media by hypotonic Cl- resulted in strong v

44 Short-term isotonic Cl- substitution experiments performed in the p

45 o independent methods (CO2 "conditioning" or isotonic Cl- substitution), are tested for CMC using two

46 These concentrations are far from the isotonic condition of PBS ( approximately 150 mM) that i

47 (0.26 M) and 0.30 M sucrose are biologically isotonic conditions (275-299 mOsm/kg), and retention was

48 Under isotonic conditions (300 mOsm), human CLN3 was found in

49 crom), under acidic (granule pH) and neutral isotonic conditions (extra-cytoplasmic pH), for GrB.SG i

50 es Ser-96 of human KCC3 is phosphorylated in isotonic conditions and becomes dephosphorylated during

51 e message of the gamma subunit was absent in isotonic conditions and increased with higher tonicity i

52 ysis demonstrating only minor staining under isotonic conditions and the substantial presence in chro

53 l water permeability (Pd) was measured under isotonic conditions by pulsed field gradient NMR.

54 Restoration of isotonic conditions elicited a prompt recovery in V(c) t

55 e membrane vesicles (MV) were isolated under isotonic conditions from human T lymphoblastoid cells MT

56 IMCD3 cells, nuclear export of TonEBP under isotonic conditions involves CRM-1 but under hypertonic

57 Reducing [Cl(-)](o) under isotonic conditions positively shifted the reversal pote

58 Cells grown in isotonic conditions showed complete absence of immunosta

59 The half-life of AQP1 protein in isotonic conditions was approximately 4 h, whereas hyper

60 hionine, the half-life of AQP1 protein under isotonic conditions was found to be <4 h.

61 le mutant KCC3-S96A/T991A/T1048A activity in isotonic conditions was significantly higher, and it was

62 Reconstitution of isotonic conditions with specific osmoles or inhibition

63 MDCK cells, blocks cell proliferation under isotonic conditions, and augments hypertonicity-induced

64 In isotonic conditions, KCCs are inactive and phosphorylate

65 Under isotonic conditions, NPPB (165 microm) blocked inward cu

66 ly phosphorylated in plasma membrane KCC3 in isotonic conditions, suggesting that dephosphorylation i

67 Under isotonic conditions, the current activated slowly with a

68 Under isotonic conditions, there was constitutive activity of

69 Under isotonic conditions, therefore, the tendon organs showed

70 By extruding Cl(-) from the neuron under isotonic conditions, this transporter maintains a low co

71 Under isotonic conditions, tumor necrosis factor-alpha (TNF-al

72 aseline whole-cell currents were small under isotonic conditions.

73 or constitutive K(+)-Cl(-) cotransport under isotonic conditions.

74 ement in cell survival in hypertonic but not isotonic conditions.

75 e UT-A 1.3-kb construct under hypertonic and isotonic conditions.

76 sport K(+) and Cl(-) out of the neuron under isotonic conditions.

77 ng constitutive K(+)-Cl(-) cotransport under isotonic conditions; the other three KCCs are exclusivel

78 Our findings show diaphragm isometric and isotonic contractile abnormalities in a murine model of

79 an age-related decline in the isometric and isotonic contractile function of permeabilized slow (MHC

80 ssessed in vitro diaphragmatic isometric and isotonic contractile function.

81 Further, isotonic contractile properties of the diaphragm were af

82 ical ventilation on diaphragmatic isometric, isotonic contractile properties, or the expression of mu

83 ensitivity of tendon organs to steady-state, isotonic contractions of single and groups of in-series

84 ssive slowdown in shortening velocity during isotonic contractions was greatest in fast-twitch fibres

85 tro motility assays and during isometric and isotonic contractions within single muscle fibers.

86 pertonic medium and was weakly detectable in isotonic controls.

87 No such modulation was observed in the isotonic cortex.

88 net fluid absorption (J(V)), as predicted by isotonic coupling between ion and fluid transport.

89 ce between study groups in the proportion of isotonic crystalloid administered that was saline.

90 Saline made up a larger proportion of the isotonic crystalloid given in the saline group than in t

91 ic crystalloid), or hypertonic (3 mL/kg/hour isotonic crystalloid plus 1.2 mL/kg/hour 7.5% NaCl).

92 luid protocol groups: euvolemic (3 mLkg/hour isotonic crystalloid), hypervolemic (15 mL/kg/hour isoto

93 ic crystalloid), hypervolemic (15 mL/kg/hour isotonic crystalloid), or hypertonic (3 mL/kg/hour isoto

94 Hyponatremia was apparent in the isotonic crystalloid- and colloid-treated animals, but n

95 he caveolin-1 in the caveolae of cells under isotonic culture.

96 x vivo was reduced under hypertonic, but not isotonic, culture conditions.

97 he use of an atraumatic injection technique, isotonic diluent, a low-infusion pressure, and a small i

98 The afferent nerve firing induced by isotonic distension of the bladder (10-40 cmH(2)O) was i

99 so decreased by 33-55% BAN firing induced by isotonic distension of the bladder at 10-40 cmH(2)O pres

100 meters), and microbiological safety of a new isotonic drink made of lemon and maqui berry over a comm

101 This method was able to quantify SY in isotonic drinks and orange sodas, in the range of 7.8-39

102 ters were affected by the heat, although the isotonic drinks remained with attractive red colour duri

103 30min compared to 2-PMPA administered in an isotonic enema vehicle.

104 in colorectal tissue, whereas hypertonic and isotonic enemas provided markedly reduced drug retention

105 essing clones acidify quite extensively upon isotonic exchange of Cl- and then rapidly alkalinize upo

106 ely 3000 kDa) was predominantly extracted in isotonic Extract A (70.1 +/- 6.0%) and PBS (37.7 +/- 3.2

107 Is isotonic fluid associated with a lower incidence of hypo

108 ed the therapeutic potential of hydrodynamic isotonic fluid delivery (HIFD) to the left renal vein 24

109 Compared with hypotonic fluid, isotonic fluid is associated with a lower incidence of h

110 el and water cotransport could contribute to isotonic fluid transport across the intestinal brush bor

111 Of 110 enrolled patients, 54 received isotonic fluids and 56 received hypotonic fluids.

112 Perioperative isotonic fluids should be infused at 20-40 ml/kg over 2-

113 s was strongly correlated with the preceding isotonic force (r = 0.99, P < 0.001).

114 Thus, isotonic force did not influence V(u) (mean: 2.84 +/- 0.

115 ortening velocity (V(u)), thereby modulating isotonic force from 0 to 0.34 F(o), respectively.

116 We conclude that isotonic force modulates +dF/dt(R) independent of change

117 The influence of isotonic force on +dF/dt(R) was assessed by imposing uni

118 n facilitates transfer of OHC displacements (isotonic forces) for cochlear amplification and neural e

119 followed midmorning by a 90-min infusion of isotonic glucose (15 g, 235 kJ) or saline to the duodenu

120 Whereas isotonic glucose and mannitol solutions had no vasoactiv

121 lutions had no vasoactivity in aortic rings, isotonic glucose produced a selective, insidious, and ti

122 This isotonic glucose-mediated vascular relaxation can be att

123 vel at 48 hours was 139.9 (2.7) mEq/L in the isotonic group and 139.6 (2.6) mEq/L in the hypotonic gr

124 h group developed hypertension, and 2 in the isotonic group developed edema.

125 or thirst or salt appetite in response to an isotonic hypovolemic challenge.

126 ing increase in fecal sodium salts causes an isotonic increase in fecal water output.

127 Usage of isotonic intravenous saline during the critical period i

128 Isotonic intravenous solutions should be infused in volu

129 ee fractionation techniques, NaBr gradients, isotonic iodixanol, and sucrose gradient centrifugation.

130 extraluminal bath using three paradigms: (1) isotonic K(+) (K(iso)) where increases in K(+) were offs

131 cell through a patch pipette filled with an isotonic KCl solution of pH 3.0.

132 Inhibition of both isometric as well as isotonic kinetics demonstrates that viscous resistance t

133 the test or to drink more water than did the isotonic load.

134 ce-velocity relationship to zero load during isotonic loading.

135 since cells do not have to be resuspended in isotonic low conductivity media.

136 leukocytes where the cells are exposed to an isotonic lysis buffer for less than 40 s, after which th

137 Our study results support the notion that isotonic maintenance fluid administration is safe in gen

138 llular ion depletion by local perfusion with isotonic mannitol failed to reduce the gating charge fur

139 t primary astrocyte cultures were exposed to isotonic media (122 mM NaCl) for 15 min, followed by 45-

140 Na+ currents were small when cells were in isotonic media but could be increased by inhibiting cons

141 study demonstrated that Chen Medium (CM), an isotonic media enriched with nonlactate-generating high-

142 events were less than 7% of those evoked in isotonic media.

143 eagents that did not affect cell survival in isotonic media.

144 ion in plasma membrane in potassium-depleted isotonic medium (0.5 or 2 mEq/L KCl) versus cytoplasmic

145 urs; afterward, the medium was replaced with isotonic medium (285+/-4 mOsm) containing 40 mM galactos

146 cytoplasmic distribution in normal potassium isotonic medium (4 mEq/L).

147 Changing from a hypertonic to isotonic medium (relative hypotonicity) decreased the me

148 l, mannitol, or urea for 4 h and returned to isotonic medium before LPS stimulation.

149 The return of cells to isotonic medium rapidly promoted the phosphorylation of

150 pression was elevated, whereas the return to isotonic medium reduced AQP1 expression in a time-depend

151 In monolayer cells in isotonic medium, SLC26A7 showed punctate distribution th

152 On reshrinking in isotonic medium, tension reduced to 0.02 mN/m, and at th

153 ne levels within hours of returning cells to isotonic medium.

154 use inner medullary collecting duct cells in isotonic medium.

155 ol efflux from cell to galactose-containing, isotonic medium.

156 the medulla) but was reduced only mildly in isotonic medium.

157 nd ipratropium bromide with either 2.5 mL of isotonic MgSO(4) (250 mmol/L; 151 mg per dose; MgSO(4) g

158 Overall, nebulised isotonic MgSO(4), given as an adjuvant to standard treat

159 Isotonic MnCl(2) did not cause cell death at the injecti

160 re, we performed intracortical injections of isotonic MnCl(2), comparisons of preinjection and postin

161 first to formally apply a tool that uses an isotonic (monotonic) regression approach to this area of

162 Epicardial placement of isotonic neutral phosphate buffer, but not saline, preve

163 s rapidly convert to inactive monomers in an isotonic, neutral pH environment.

164 Darby canine kidney cells were treated under isotonic or hypertonic conditions with the nitric oxide

165 sthesia only, anesthesia 1 h prior to either isotonic or hypertonic saline injection or no anesthesia

166 r 20% of albumin) or crystalloids (n = 1443; isotonic or hypertonic saline or Ringer lactate solution

167 he peritoneum and were filled with either an isotonic or hypertonic solution.

168 he dependence of the transported osmolarity (isotonic or hypertonic) on channel radius, length, and o

169 Patients were randomized to receive isotonic or hypotonic intravenous fluid at maintenance r

170 We also did isotonic organ bath experiments to assess muscle strip s

171 ed by co-incubating celecoxib and melanin in isotonic phosphate-buffered saline.

172 ss in case of obesity, engagement in regular isotonic physical activity, reduced sodium diet (<100 mm

173 arly, lactate that was dissolved in a low-pH isotonic physiologic salt solution produced significant

174 Salivary gland acinar cells produce an isotonic, plasma-like fluid, which is subsequently modif

175 framework based on parallel linear (SAM) and isotonic regression (PIR) methods identified 95 and 53 p

176 pool adjacent violators algorithm (PAVA) for isotonic regression and inherits its linear-time computa

177 We apply the isotonic regression approach to a study of gene expressi

178 aluating the trend of spatial patterns using isotonic regression, we show that in yeast and prokaryot

179 n of NHE-1 with pharmacological agents or by isotonic replacement of sodium in the perfusate with cho

180 by pharmacological inhibitors of NHE-1 or by isotonic replacement of sodium, closely linking the prot

181 ith Ricrolin TE (n = 35) or epi-off CXL with isotonic riboflavin (n = 26) in 1 academic treatment cen

182 cross-linking efficacy or safety, given that isotonic riboflavin solution is viscous and each install

183 osmotic medium was prepared by supplementing isotonic Ringers solution with sucrose.

184 riuretic response to intravenous infusion of isotonic saline (2% body weight, given over 5 min).

185 = 133 Pa) and resuscitated after 45 min with isotonic saline (2x volume of shed blood).

186 Injection of isotonic saline (control) did not alter the responses of

187 151 mg per dose; MgSO(4) group) or 2.5 mL of isotonic saline (placebo group) on three occasions at 20

188 , is the culprit in dilutional hyponatremia, isotonic saline administration may further depress the s

189 In dogs, isotonic saline at 0-4 degrees C, flushed into the aorta

190 balloon-tipped catheter, an aortic flush of isotonic saline at 2 degrees C (at a rate of 1 L/min), u

191 s at high risk were hydrated with 1000 mL of isotonic saline before and after contrast material expos

192 al nucleus of the solitary tract compared to isotonic saline controls.

193 e of inhaled hypertonic saline compared with isotonic saline did not reduce the rate of pulmonary exa

194 ar electrosurgery include the ability to use isotonic saline during surgery, reduced blood loss and l

195 After 15 mins, 80 mL/kg isotonic saline fluid was infused at 4.4 mL/min.

196 hydration protocol consisting of intravenous isotonic saline for 12 h after PCI.

197 = -2.46 to 0.06), and remained stable in the isotonic saline group (n = 13) at 0.81 (95% CI = -0.40 t

198 ts, perfusion solution was supplemented with isotonic saline in lieu of a drug.

199 eived a median (range) 3230 mL (390-7300) of isotonic saline in the first 6 hours and 5450 mL (710-13

200 fic to sweet taste because neither water nor isotonic saline infusion affected forepaw escape latenci

201 ete a short-term sodium load (5% body weight isotonic saline infusion over 30 minutes) and a long-ter

202 Isotonic saline is the most commonly used crystalloid in

203 Lung injury was developed by isotonic saline lavage until the PaO2 decreased to 100-1

204 tative analysis revealed that treatment with isotonic saline or 200 ng senktide resulted in the diffe

205 pattern was not shown by rats that received isotonic saline or systemic 2-deoxy-d-glucose (a glucose

206 Single injections of isotonic saline raised the plasma concentrations to a si

207 214 subjects during the "placebo" infusion (isotonic saline solution) immediately preceding the lact

208 Administering nebulized isotonic saline to these "high-producer" individuals dim

209 traperitoneal injection of either ethanol or isotonic saline using c-Fos expression as a marker of ne

210 saccharide (3 mg/kg intravenously, n = 9) or isotonic saline vehicle (control, n = 5) administration,

211 Treatment groups received isotonic saline vehicle (control; n = 6), lipopolysaccha

212 Following isotonic saline vehicle (control; n = 6), lipopolysaccha

213 During short-term isotonic saline volume loading, metoprolol CHF rats excr

214 n right atrial pressure) was measured during isotonic saline volume loading.

215 In addition, 1 mL of isotonic saline was administered intravenously within si

216 e stability of Na(2)[(99m)Tc(CO)(3)(NTA)] in isotonic saline was assessed for 24 h and was further ev

217 n commenced for 3 minutes, and dantrolene or isotonic saline was infused at the onset of cardiopulmon

218 nd 77% of SON neurons, respectively, whereas isotonic saline with anesthesia and anesthesia alone res

219 rosemide (5 mg) or vehicle solution (sterile isotonic saline) and sacrificed either 1.75 h (short-sur

220 hieved >99.8% salt removal with 154 mM NaCl (isotonic saline) at 1 muL/min.

221 ment received injections of vehicle (sterile isotonic saline) instead of furosemide.

222 volume of vehicle (30% Solutol HS15 and 70% isotonic saline, 0.37 ml/kg, n=5) or saline (0.37 ml/kg,

223 eceive either rhEPO (3000 IU/kg) or placebo (isotonic saline, 0.9%) intravenously within 3 hours, at

224 nd the control group (n = 163) received 0.9% isotonic saline, nebulized twice daily for 48 weeks.

225 (18)F-TFB was eluted from the cartridge with isotonic saline, passing through 3 neutral alumina cartr

226 This can be treated with isotonic saline, whereas potassium/magnesium administrat

227 ressure 40-50 mmHg, or volume expansion with isotonic saline.

228 (P<0.05) higher VAS scores than infusion of isotonic saline.

229 uced muscle pain compared to the infusion of isotonic saline.

230 saline followed by either acidic or neutral isotonic saline.

231 to 7 d, and a control portion was placed in isotonic saline.

232 mum dose 750 mL) or the equivalent volume of isotonic saline.

233 ng epithelial sodium channel blocker (P308); isotonic saline; or no treatment, using a nebuliser inte

234 7 RTNs formed stable particles of <200 nm in isotonic salt buffers, compared with 4-microm particles

235 e isolation of large factory fragments under isotonic salt concentrations in <72 h.

236 Isotonic salt solution and normal donor samples of milk,

237 is method to mice that were dialyzed with an isotonic salt solution under quiescent conditions for 1

238 e pH is slightly reduced from 7.4 to 6.6, in isotonic salt solutions that simulate the acidic extrace

239 hypertonic challenge monotonically around an isotonic "set point" and that these responses depend on

240 hortening became markedly curvilinear during isotonic shortening in all three muscle types.

241 consequence of the KCl loss and concomitant isotonic shrinkage caused by increased [Ca2+]i as it per

242 patients with nonoliguric renal failure and isotonic sodium bicarbonate infusions to prevent radioco

243 efit of using sodium bicarbonate rather than isotonic sodium chloride for preventing contrast-associa

244 ether hydration with bicarbonate rather than isotonic sodium chloride reduces the risk of contrast-as

245 otide) infusion (150 mg/h); (3) placebo with isotonic sodium chloride solution (saline) infusion (fas

246 Previously, isotonic solution (IS) enriched with beta-hydroxybutyrat

247 locker furosemide produced cell shrinkage in isotonic solution and blocked cell swelling normally ind

248 The cannula was perfused with isotonic solution and hourly samples of perfusate were c

249 The isotonic solution consisted of HEPES buffer with 40% of

250 tion of a relatively large volume (10 ml) of isotonic solution containing a radiolabeled protein that

251 ately after reperfusion and perfused with an isotonic solution for 48 hr.

252 In contrast, the isotonic solution resulted in a net loss or an insignifi

253 Lengthening the dwell of the isotonic solution to 24 h increased R(mean) to >0.90.

254 , whereas hypotonic solution was the same as isotonic solution without sucrose.

255 In isotonic solution, niflumic acid produced swelling, sugg

256 osure of cells in the kiss and hold state to isotonic solutions evoked massive release.

257 +-free and K+-free media and Ca2+-containing isotonic sucrose solution, were investigated.

258 The increases are much greater under isotonic than under hypertonic conditions.

259 d against 10, 20, 30, 50 or 100 mM NaCl made isotonic to 154 mM NaCl by supplementing with sorbitol w

260 himeric cDNAs to localize the determinant of isotonic transport in KCC2.

261 ansport is abrogated by calyculin A, whereas isotonic transport mediated by KCC chimeras and KCC2 is

262 in just distal to the PEST sequences confers isotonic transport on KCC4.

263 esidues 1021-1035 of KCC2 are sufficient for isotonic transport.

264 abeculae from the rat heart to determine the isotonic velocity transient following a stepwise reducti

265 erimental model to induce uniform and stable isotonic volume changes in RBC populations from healthy

266 Both i.v. infusion of ang II and isotonic volume expansion significantly increased dialys

267 cological agents were effective in producing isotonic volume responses in human airway epithelia but

268 theses, "hypotonic [low salt]/defensin" and "isotonic volume transport/mucus clearance," attempt to l

269 the speed of the early rapid shortening (the isotonic working stroke) increase by reducing T from app