ライフサイエンスコーパス: isotopic

1 multi-elemental (Fe, Zn, Mn, Cu, Li, Sr) and isotopic ((13)C/(12)C, (18)O/(16)O) marker investigation

2 The oxygen-18 isotopic ((18)O) composition in CO2 provides an importan

3 ow temperature NMR, UV-vis spectroscopy, and isotopic ((18)O) labeling experiments.

4 yses of calcined Si-SSZ-70 at natural (29)Si isotopic abundance (4.7%) establish the through-covalent

5 This package estimates the isotopic abundance of the employed stable isotope (eithe

6 eadily be acquired on intact mAbs at natural isotopic abundance, and small changes in chemical enviro

7 Indeed, barium-isotopic analyses of barites from the Paleoarchean Dress

8 The nano-scale texture and isotopic analyses provide a partial record of the chemic

9 capture HONO for offline nitrogen and oxygen isotopic analysis (delta(15)N and delta(18)O) using the

10 venous blood samples were collected for iron isotopic analysis and measurement of iron status biomark

11 llections of ambient HONO (0.4-1.3 ppbv) for isotopic analysis and was found to be robust for low con

12 ral Europe for the Holocene, based on stable isotopic analysis of an ice core recovered from a cave i

13 Isotopic analysis of CH4 showed a dominance of acetoclas

14 Isotopic analysis of HONO may provide a tool for trackin

15 Here we show that accurate U-Pb isotopic analysis of nanoscale domains of baddeleyite ca

16 We demonstrate rapid isotopic analysis of solid uranium oxide at a precision

17 tool that has been used in combination with isotopic analysis to define the nature of the active spe

18 The aim was to investigate the ability of isotopic analysis to trace the geographical origin of tr

19 uantitative Hg and MeHg determination and Hg isotopic analysis via cold vapor generation multicollect

20 Combined isotopic and chemical characteristics projected for thes

21 t end-members are required to explain the Hg isotopic and concentration variation observed in the Sou

22 In contrast, radiometric, isotopic and elemental records of anthropogenic activity

23 High-resolution geochemical, isotopic, and (14)C analyses of a sedimentary core from

24 production areas were sampled for chemical, isotopic, and groundwater-age tracers to investigate the

25 heric methane increase, thus reconciling the isotopic- and ethane-based results.

26 ch ion microprobe analyses revealed hydrogen isotopic anomalies at a submicrometric spatial resolutio

27 tremely negative Shunga-Francevillian carbon isotopic anomaly.

28 chanisms in intertidal sediments using novel isotopic approaches and microsensors in flow-through inc

29 ition of each species' niche in at least one isotopic axis.

30 After updating both the total and isotopic budgets for atmospheric methane with these revi

31 the one hand, dissolved loads have peculiar isotopic characteristics and carry mainly limestone-deri

32 This study demonstrates that isotopic characterization of multiple tracers is necessa

33 ssibility of cysteine thiols by differential isotopic chemical footprinting.

34 The nitrogen isotopic composition (delta(15)N) of NOx (NO + NO2) was

35 riations of atmospheric water vapour and its isotopic composition (delta(18) OV ) influence water and

36 ave developed a new method for measuring the isotopic composition (delta(18)O and deltaD) of differen

37 As such, variations in the sulfur isotopic composition (delta(34)S) of sedimentary sulfate

38 nown but differing delta(13)C and delta(18)O isotopic composition allows standard uncertainties of 0.

39 We have determined the isotopic composition and the carotenoid contents of 38 e

40 The isotopic composition data are collected independently in

41 This is the first case study of Sr isotopic composition determination in such ancient decid

42 pths (200-1,300 m), contrasting with heavier isotopic composition in deep waters.

43 to sort out all particles according to their isotopic composition in one analysis.

44 study suggests that the variability in iron isotopic composition in planetary objects cannot be due

45 bits large and enigmatic departures from the isotopic composition of abiogenic calcite, known as vita

46 The isotopic composition of all standards was value assigned

47 In order to characterize the stable isotopic composition of aragonitic pteropod shells and t

48 The initial isotopic composition of atmospheric Xe remains unknown,

49 cycle that are independent of changes to the isotopic composition of carbon input.

50 imation of enzymatic activity of CA from the isotopic composition of CO2.

51 We present the Sr isotopic composition of enamel of the most ancient decid

52 erefore strongly influence the elemental and isotopic composition of hams.

53 is method enables future work to utilize the isotopic composition of HONO for studying HONO chemical

54 ternative controls on the sedimentary sulfur isotopic composition of marine pyrite by examining a 300

55 Variation across climate gradients in the isotopic composition of nitrogen (N) and carbon (C) in f

56 ect and simultaneous analysis of the age and isotopic composition of nuclear material at the particle

57 levated temperatures alters the chemical and isotopic composition of oceanic crust.

58 Volatilization causes changes in the isotopic composition of organic compounds as a result of

59 ds, and estimates of the last glacial oxygen isotopic composition of precipitation based on global ci

60 We measured the titanium isotopic composition of shales to constrain the chemical

61 Isotopic composition of sharks sampled in reef and seagr

62 plied to ensure accurate measurements of the isotopic composition of the CO2 in ultradry air, express

63 ta(13)C-CH4 and deltaD-CH4 correspond to the isotopic composition of the gas reservoir.

64 (iii) We account for changes in the oxygen isotopic composition of the ice sheet by using isotope-e

65 tz (Barberton, South Africa) that reveal the isotopic composition of the paleo-atmosphere at approxim

66 Analysis of the THg concentration and Hg isotopic composition of these environmental samples indi

67 This variability in stable isotopic composition of tissues is likely to be a result

68 u spectroscopic measurements of the evolving isotopic composition of water vapor during cirrus format

69 The xenon isotopic composition shows deficits in heavy xenon isoto

70 mpactor that formed the Moon probably had an isotopic composition similar to that of the Earth, hence

71 Comparison of shell oxygen isotopic composition to depth changes in the calculated

72 with different mole fractions but identical isotopic composition was demonstrated to be highly accur

73 fluences on pteropod shell carbon and oxygen isotopic composition.

74 produces one or the other, depending only on isotopic composition.

75 found that shales of all ages have a uniform isotopic composition.

76 w a clear alteration of their initial oxygen isotopic composition.

77 Here, Cd isotopic compositions (delta(114/110)Cd) of archived fer

78 cts," that is, deviations from elemental and isotopic compositions at thermodynamic equilibrium.

79 Depth profiles of Hg isotopic compositions for bottomfish (excludung C. ignob

80 Lead concentrations and isotopic compositions measured in the sediments of the h

81 Boron concentrations and isotopic compositions of atmospheric dust and dissolved

82 ere, we combine analysis of biomolecular and isotopic compositions of lipids preserved in prehistoric

83 Our modelling implies that the isotopic compositions of magnesium, silicon and iron, an

84 en inferred from bulk analyses of the carbon isotopic compositions of pre-2,500 Ma kerogens, these in

85 h recent indications from lunar carbon and S isotopic compositions of primitive lunar materials.

86 The isotopic compositions of the main constituents of planet

87 The isotopic compositions of the total water evolved from a

88 of the SRS environment, revealing plutonium isotopic compositions, e.g., (244)Pu, that reflect the u

89 ogeneous assortment of embryos with distinct isotopic compositions.

90 ite meteorites have almost indistinguishable isotopic compositions.

91 the membrane, (ii ) control of the protein's isotopic constitution, and (iii ) control over the lipid

92 e astrochronologic calibration of the Oxygen isotopic curves, and to assess the calibrations of (40)A

93 ent a synthesis of ammonite biostratigraphy, isotopic data and high precision U-Pb zircon dates from

94 We used tree-ring isotopic data and structural equation modeling to examin

95 ved and particulate multi-element and barium-isotopic data from Lake Superior that evidence pelagic b

96 ce of contrasting terrestrial signals in the isotopic data implies that factors other than local land

97 diometric) age, indicating the usefulness of isotopic data in retaining information on Pb sources and

98 The tungsten isotopic data negatively correlate with (3)He/(4)He.

99 graphic variations (>76 per thousand) in the isotopic data reported here are among the largest ever o

100 ironmental and physiological controls on the isotopic data.

101 ross scales by analyzing the stable nitrogen isotopic (delta(15)N) values of the scleractinian coral

102 distribution and lack clear osteological or isotopic differentiation between populations.

103 ivity pump-probe anisotropy measurements and isotopic dilution clearly reveal that the decay of the d

104 oncentrations by using liquid chromatography isotopic dilution tandem mass spectrometry in a cross-se

105 ients in foliar N isotope (delta(15)N) and C isotopic discrimination (Delta(13)C) measured in 755 spe

106 an increase has occurred in the (13)C/(12)C isotopic discrimination of land photosynthesis.

107 ffer gases, deuterium incorporation pattern (isotopic distribution), deuterium incorporation pattern

108 al heterogeneity was also assessed by HDX MS isotopic distribution.

109 s critical for correctly interpreting stable isotopic distributions and for predicting the fate of me

110 e fact that MS isotopic patterns reflect the isotopic distributions.

111 tested substance was (13)C labeled, and this isotopic effect also can be corrected automatically, if

112 ism and yields dynamic curves for positional isotopic enrichment and spin-spin multiplets.

113 Isotopic enrichment of carbon substrates and intracellul

114 ld improvement in polariton lifetime through isotopic enrichment of hexagonal boron nitride (hBN).

115 for many factors, including patterns of leaf isotopic enrichment, the maintenance of mesophyll water

116 alytically to obtain concise expressions for isotopic enrichments, with focus on mass-independent iso

117 Isotopic entrainment has shown the observed catalyst-sub

118 and accuracy that is present in each peptide isotopic envelope measurement.

119 The consequent isotopic envelopes in mass spectra can reveal the ion st

120 dent of the Zn:ligand ratio used, indicating isotopic equilibrium and that the results were not signi

121 e probably driven by incomplete chemical and isotopic equilibrium between CO2 and bicarbonate under t

122 esponse to WAIS loss is in opposition to the isotopic evidence at 128 ka.

123 evitation with aerosol optical tweezers with isotopic exchange (D2O/H2O) to measure the water diffusi

124 This shows that isotopic exchange (the addition of only one neutron) may

125 (18)O/(16)O isotope ratios during oxygen-18 isotopic exchange between (12)C(16)O(16)O and H2(18)O of

126 Rate studies of the isotopic exchange of benzene and monosubstituted arenes

127 erences produced by VOCs in natural samples, isotopic exchange with structural oxygen, etc.) are disc

128 me enclosed in and isolated from any further isotopic exchange.

129 Both the temperature and the isotopic excursion are well-documented by terrestrial an

130 association with the extreme positive carbon isotopic excursion known as the Lomagundi Event.

131 (2) in a microbial electrochemical cell, and isotopic experiments supported AOM-EET to the anode.

132 ify ion adducts, duplicate peak reports, and isotopic features of the main monoisotopic metabolites.

133 with primary amine groups were reacted with isotopic formaldehydes to synthesize ISs and standards.

134 64)Zn ratios, from which the three different isotopic forms of Zn were quantified.

135 ls (iron precipitates, Feppt), with distinct isotopic fractionation (epsilon(56)Fe) values determined

136 However, isotopic fractionation between liquid and vapour, follow

137 However, the extent of iron isotopic fractionation between molten metal and silicate

138 the mechanisms involved in its depletion and isotopic fractionation compared with other reservoirs in

139 Isotopic fractionation during MoS4(2-) transformation wi

140 The calculated isotopic fractionation factors of epsilonC = 3 and epsil

141 Isotopic fractionation of 1,2-DCA (epsilonbulk(C) and ep

142 a sensitive technique for the measurement of isotopic fractionation of protonated carbons at natural

143 However, the isotopic fractionation produced by adsorption may compli

144 ortant insight into the variation of rate in isotopic fractionation reaction regulated by carbonic an

145 CO2 with increments of CA activities during isotopic fractionation reaction.

146 ing a simple procedure and without observing isotopic fractionation.

147 ystem shows complete capture of HONO without isotopic fractionation.

148 gical reactions that have distinctive stable isotopic fractionations.

149 ielding a catalyst with reduced activity for isotopic H/D exchange reactions.

150 These isotopic heterogeneities, usually referred to as hot and

151 yde) and requires no postlabeling cleanup or isotopic impurity corrections.

152 iron absorption), assessed by measuring the isotopic label abundance in erythrocytes 14 days after a

153 ns were subsequently validated through (13)C isotopic labeling and metabolic flux analysis in stored

154 Here we employ isotopic labeling combined with hyperspectral, quantitat

155 - in vivo research reports important stable isotopic labeling enrichment differences into the DNA nu

156 The isotopic labeling increases the vibrational lifetime abo

157 ity biotinylation in combination with stable isotopic labeling of amino acids in cell culture (SILAC)

158 We couple isotopic labeling of cyanobacterially derived dissolved

159 skites is demonstrated through the effect of isotopic labeling of the methylammonium (MA) component o

160 revious studies leads to the conclusion that isotopic labeling of the protein may have different effe

161 ent the first direct LC-MS/MS study (without isotopic labeling or hydrolysis) of primary oxidation si

162 Segmental and specific isotopic labeling reduce degeneracy, but experiments to

163 sitivity, we combined specific and segmental isotopic labeling schemes with dynamic nuclear polarizat

164 However, isotopic labeling simultaneously shifts the absorption t

165 Here, we introduce an isotopic labeling strategy in the gram-positive bacteriu

166 (18)O and (2)H isotopic labeling studies confirm the transfer of atoms

167 conclusions were substantiated by EPR data, isotopic labeling studies, and the use of radical scaven

168 In this work, we use a combination of isotopic labeling studies, mechanistic probes, and DFT c

169 olyelectrolyte complex, PEC, using sensitive isotopic labeling techniques.

170 nt method for alkyl and aryl carboxylic acid isotopic labeling using a single reagent.

171 By combining in situ gas analysis, isotopic labeling, and a surface carbonate titration, we

172 e by a combination of in situ spectroscopic, isotopic labeling, and mass spectroscopic investigations

173 In this work, a novel strategy integrating isotopic labeling, chemical enrichment and multiplexed p

174 te pools, which can be distinguished through isotopic labeling, have not been considered in past synt

175 philes were conducted using a combination of isotopic labeling, NMR spectroscopy, kinetic modeling, s

176 elucidated unambiguously by (13)C and (15)N isotopic labeling.

177 2 fixation rates directly without a proxy or isotopic labeling.

178 Coccomyxa subellipsoidea C169, using stable isotopic labeling.

179 resonance Raman spectroscopy and verified by isotopic labeling.

180 ids in the biological extract with no use of isotopic labeling.

181 n demonstrated previously by Balaban through isotopic labeling.

182 bon cosolvent (hexane versus toluene) and to isotopic labeling.

183 Isotopic labelling confirms that the carbon and oxygen a

184 promotes extrusion of azobenzene, where H-/D-isotopic labelling finds no isotopomer cross-over and th

185 bridge-donor 'fork' system: asymmetric (13)C isotopic labelling of one of the two -C identical withC-

186 arison of the N-terminome, by terminal amine isotopic labelling of substrates between wild type and A

187 etiolated seedlings, we used terminal amine isotopic labelling of substrates with tandem mass tags (

188 Isotopic labelling studies support a mechanism where the

189 containing differential proximal and distal isotopic labels and measuring USP7 binding by nuclear ma

190 on-native and rigidifying structural motifs, isotopic labels, and a variety of bioorthogonal handles

191 n compared erythrocyte incorporation of iron isotopic labels, changes in body composition, iron statu

192 multaneously resolves both the geometric and isotopic makeup of an object.

193 Increased isotopic mass in F159Y PNP causes more efficient transit

194 ree of chlorination, CPs have highly complex isotopic mass patterns that often overlap, even when app

195 e elucidation tools such as diagnostic ions, isotopic matches, and collision cross sections were appl

196 Based on isotopic measurements of potential baseline sources, amb

197 Isotopic measurements on junipers growing in southern Ca

198 Nd and Sr isotopic measurements suggest that a distinct source may

199 cesses on Earth and other planets from water isotopic measurements.

200 n optics scheme leads to cloaks that possess isotopic media, thus provides a prospective way to facil

201 Rather, our isotopic methane budget points to a marked increase in f

202 Here, we present dual stable isotopic methane records [delta(13)CH4 and deltaD(CH4)]

203 recipitated in an intracellular chemical and isotopic microenvironment, coccolith calcite exhibits la

204 The Pb, Sr, Nd, and Hf isotopic mixing arrays show that the Archean EM I materi

205 Thousands of tons of isotopic mixtures are processed annually for heavy-water

206 nities for metal can be used to decipher the isotopic nature of the Earth's accreting material throug

207 The isotopic nature of these bodies is unknown.

208 hesis and to examine the correlation between isotopic niche breadth and morphology.

209 I examined the isotopic niche dynamics of four common sympatric desert

210 We investigated isotopic niche width in a small radiation of South Ameri

211 on between the widths of hydrogen and oxygen isotopic niches (which estimate breadth of elevational r

212 range) and widths of the carbon and nitrogen isotopic niches (which estimates the diversity of resour

213 o found a positive correlation between broad isotopic niches and wing morphology.

214 Hg values in SIBER enabled us to estimate Hg isotopic niches, successfully discriminating several pop

215 ruits showed a typical range for one or more isotopic parameters that can be used to verify the authe

216 The isotopic partitioning of soil Cd sources in this system

217 function and newly developed search function Isotopic Pattern Algorithm (IPA).

218 Using accurate mass, isotopic pattern and MS/MS fragmentation, 167 precursors

219 derivatives, on the basis of accurate mass, isotopic pattern and MS/MS fragmentation.

220 s the effect of a single atom on the overall isotopic pattern grows smaller.

221 Common approaches use the isotopic pattern of a compound measured using mass spect

222 ft time coefficients of variation < 1.0% and isotopic pattern root-mean-square deviations of 0.5-1.5%

223 pecific molecular formula to an experimental isotopic pattern.

224 Because isotopic patterns cannot definitively distinguish these

225 package, a tool able to extract and analyze isotopic patterns from liquid chromatography-mass spectr

226 ossible route is to exploit the fact that MS isotopic patterns reflect the isotopic distributions.

227 ucts based on accurate masses, (35)Cl/(37)Cl isotopic patterns, and MS/MS spectra.

228 aining accurate m/z values, retention times, isotopic patterns, full MS, and MS/MS spectra.

229 Importantly, common adduct species and isotopic peaks are accounted for and are shown to play a

230 Isotopic peaks of the selected precursor can be removed,

231 .e., accuracy in measuring the abundances of isotopic peaks, remains less studied.

232 tokes Raman scattering (CARS) microscopy and isotopic perfusion experiments.

233 Isotopic perturbation of equilibrium NMR studies along w

234 L. ambigua shows a different isotopic profile than all other Laccaria species.

235 Isotopic purification has enabled quantum coherence time

236 carboxylic acids, with complete retention of isotopic purity from the [(13)CN]-NCTS used.

237 Lead isotopic ratio analysis ((206)Pb/(207)Pb) suggested a po

238 The potential for the isotopic ratio analysis of cattle tail hair in determini

239 le representatives of the atmospheric carbon isotopic ratio and can, therefore, be used to date archa

240 Both the measured Zn concentration and its isotopic ratio are correctly described using a thermodyn

241 It was also observed that both hair and milk isotopic ratio correlations exhibited separation between

242 The accuracy of using isotopic ratio in determining geographical discriminatio

243 competitive alternative to state-of-the-art isotopic ratio mass spectrometry techniques.

244 m Isernia was probably local, given that the isotopic ratio of the enamel falls within the local rang

245 (18-20 Ma) corals exhibit the same nitrogen isotopic ratio offset identified in modern corals.

246 Finally, the delta(18)O isotopic ratio was studied.

247 and Iceland, can host rare, high (3)He/(4)He isotopic ratios (up to 50 times the present atmospheric

248 vides direct and precise measurements of the isotopic ratios delta(17)O and delta(18)O in CO2.

249 Isotopic ratios of (226)Ra(/228)Ra and (87)Sr(/86)Sr ide

250 In this work the H, C, N and O isotopic ratios of 190 samples of different soft fruits

251 ining the mitochondrial genome diversity and isotopic ratios of 74 ancient remains in conjunction wit

252 U, Cs, Ba, Rb, K, and Ca isotopic ratios were determined on three CsMPs (3.79-780

253 ses only high-purity, relatively inexpensive isotopic reagents ((18)O water and deuterated formaldehy

254 ally resolved, uranium/thorium-dated, oxygen isotopic record for much of the past 45,000 years, obtai

255 Even more significantly, the isotopic record of Pb pollution proves to be an unparall

256 of marine sulfate, any change in the sulfur isotopic record preserved in pyrite (delta(34)Spyr) nece

257 Site-selective isotopic reinforcement of polyunsaturated fatty acids (P

258 The Moon bears a striking compositional and isotopic resemblance to the bulk silicate Earth (BSE) fo

259 ites and the Earth were formed from the same isotopic reservoir but they diverged in their chemical e

260 ing water isotopes, we show instead that the isotopic response to WAIS loss is in opposition to the i

261 icle examines the retention of elemental and isotopic sedimentary signatures in an industrialized est

262 of remote sensing applications that require isotopic sensitivity.

263 andidate core-forming light elements, as the isotopic shifts associated with such alloying are small.

264 The resulting multidimensional matrix of isotopic shifts is specific to isomers, providing a fund

265 and shift from C-H, SCRS also reveal several isotopic shifts of the phenylalanine band, of which the

266 The measured isotopic signal in central London (-45.7 +/-0.5 per thou

267 's College London, enabled assessment of the isotopic signal of the source mix in central London.

268 hondrites and their components have a unique isotopic signature extending from an inner Solar System

269 We compared these data with the Sr isotopic signature of local micro-mammals, the broadest

270 m the wreck location were shifted toward the isotopic signature of the sediment and, thus, the submar

271 The Sr isotopic signature was an excellent marker when Italian

272 ion rates, as well as sequential sampling of isotopic signatures (delta(13) C, Delta(14) C), microbia

273 dal marine carbonate outcrops present carbon isotopic signatures consistent with mineral-sourced auto

274 Comparison to the isotopic signatures of fish feed-derived PLFAs indicates

275 determined by functional feeding groups and isotopic signatures of nitrogen (delta(15)N), indicating

276 This isotopic similarity indicates that the material accreted

277 formulas were identified and confirmed using isotopic simulation and MS-MS fragmentation spectra.

278 experiment, we increase the coverage of the isotopic space that can be probed by obtaining the compl

279 ed by obtaining the complete distribution of isotopic species for the first two carbons of amino acid

280 atic under representation of heavier natural isotopic species, especially for high molecular weight m

281 nd filament-induced laser ablation molecular isotopic spectrometry.

282 in response to sea-level rise during Marine Isotopic Stage (MIS) 13.

283 Isotopic studies have shown that many of the world's coa

284 Results from these isotopic systems identified individuals within species t

285 pot chemical labeling strategy for attaching isotopic tags to both the N- and C-termini of tryptic pe

286 challenging at the length scales of current isotopic techniques.

287 central equatorial Pacific, based on oxygen isotopic time series from Taiwan tree cellulose that spa

288 Recent Fe isotopic tracer experiments have shown that goethite und

289 nd equilibrating the sample with appropriate isotopic tracers before the onset of the separation proc

290 Delivering isotopic tracers for metabolic studies in rodents withou

291 le protein kinetic rates were measured using isotopic tracers.

292 transform infrared spectroscopy/steady-state isotopic transient kinetic analysis) experiments demonst

293 was more than 2 per thousand higher than the isotopic value calculated using emission inventories and

294 not sampling an intermediate, syn-excursion isotopic value.

295 Hg isotopic values also provided insight on Hg contaminatio

296 ethane and carbon dioxide mole fraction, and isotopic values at King's College London, enabled assess

297 Isotopic values for the separate peaks are calculated by

298 delta(13)C, delta(2)H, and delta(18)O isotopic values were also measured.

299 ing the product of the water amounts and its isotopic values, after correcting for background.

300 thers of 12 species of Cinclodes to test the isotopic version of the resource breadth hypothesis and