ライフサイエンスコーパス: issue

1 ces are needed to address this public health issue.

2 heterogeneous analyses have not settled the issue.

3 s as the model system to directly study this issue.

4 and size of such structures is an unresolved issue.

5 though insecticide resistance is becoming an issue.

6 RAFi-based therapy is therefore an important issue.

7 al complex dynamical systems is an important issue.

8 for investment to tackle this public health issue.

9 experiments aimed at further clarifying this issue.

10 of early oral SCC is a considerable clinical issue.

11 nd hence eliminates the long-standing safety issue.

12 India-Asia collision remains an outstanding issue.

13 rtaABC, a web server that aims to solve this issue.

14 enrichments in sign language can often be at-issue.

15 t species, it can unravel plant adulteration issues.

16 Tc Nb3Sn due probably to cost and processing issues.

17 lements annotation pipeline to address these issues.

18 mellitus with particular emphasis on ocular issues.

19 similar approach should aim to overcome such issues.

20 al current) without any operating or thermal issues.

21 eveloped a simple method that resolves these issues.

22 ERG channel, which suggests no major cardiac issues.

23 ral dynamics of environmental and ecological issues.

24 m members, and operational and environmental issues.

25 uality of life by addressing critical health issues.

26 a fossil biota that sheds new light on these issues.

27 and should be increasingly applied to these issues.

28 iefs regarding six potentially controversial issues.

29 tic review and meta-analysis examining these issues.

30 hrows light on several previously unresolved issues.

31 tions, incomplete submission, and uniformity issues.

32 To tackle this issue, 172 patients with an infarct initially sparing th

33 arts and QoL with the Health Utilities Index issue 3 (HUI-3) questionnaire in 184 participants.

34 To issue a new US Preventive Services Task Force (USPSTF) r

35 the American College of Physicians recently issued a guideline titled "Nonpharmacologic Versus Pharm

36 In this issue, Aeschimann et al. (2017) demonstrate that, depend

37 This heterogeneity is caused by quality issues affecting studies of AIT with perennial allergens

38 outcomes, cost effectiveness and contextual issues affecting successful implementation.

39 , we provide a different perspective on this issue, analyzing data from an influential study reportin

40 organisation that would address survivorship issues and include friends, family, and caregivers.

41 ch can be associated with patient compliance issues and safety concerns.

42 ic series that cover the grounds of standing issues and the directions, which were discussed in the F

43 This paper highlights current and critical issues and themes in GxE research that need additional c

44 ponse, body image, intimacy and relationship issues, and overall sexual functioning and satisfaction.

45 electronic cigarettes obviate many of these issues, and provide a close simulation of smoking tobacc

46 nction/programming, common pacemaker-related issues, and remote monitoring, which are relevant to the

47 e source of amine and organoboron reactivity issues, and the origin of competing oxidation/protodebor

48 In this issue, Andino and co-workers propose that acquisition of

49 These issues are addressed by electrochemical oxidation method

50 r, immune dysregulation and gastrointestinal issues are common comorbidities.

51 ty scales, Consistency in how patient safety issues are dealt with by different preceptors, and Syste

52 These issues are geographically heterogeneous and begin among

53 t mortality; however, technical and logistic issues are limiting factors.

54 d treatment of cardiovascular and thrombotic issues associated with novel MM therapies have emerged a

55 Here we explore evolving issues associated with produced water (PW) management an

56 lish commercial application due to technical issues associated with the lack of stability and high co

57 needed to resolve procurement and regulatory issues before the introductions of IPV and bOPV.

58 mic health centers probably confront similar issues, but-except for UCSF-such centers have not been s

59 Here we address this issue by a comparative analysis of genital cortex.

60 Here, we address this issue by developing an algorithm that estimates dd-cfDNA

61 possible, and the present study probes this issue by examining four crystallographically characteriz

62 versatile methodology to tackle this design issue by exploiting the ethyne-bridged (polypyridyl)meta

63 The present study examines this issue by focusing on the role of stromal interaction mol

64 Here we addressed these issues by developing single-cell multiple displacement a

65 ken the first steps towards addressing these issues by increasing screening resolution and analyzing

66 hrough an abatement strategy to offset these issues by providing the fertilizer content in synchrony

67 mples for subpopulation discovery, and these issues can be quickly and dramatically amplified with in

68 ling of conventional algorithms and accuracy issues caused by common density functionals.

69 However, issues central to the future of health and health care i

70 In this issue, Chen et al. show that Importin-11 traffics the tu

71 , performing the first meta-analysis on this issue, comparing prognostic parameters in surgically tre

72 urrent methods do not adequately address the issues concerning combining multiple samples for subpopu

73 al public service announcements about health issues (control group).

74 easured patient resuscitation preferences on issues critical for researchers and research consumers t

75 In this issue, De et al. establish direct roles for Vps13 and it

76 method, suffer from environmental and safety issues due to their use of hazardous and explosive chemi

77 ligand core that by avoiding stereochemical issues enabled rapid synthesis of acrylate ketone, ester

78 w explains the tactics used to address these issues, evaluates the progress that has been made, and o

79 the martensitic phase is still an unresolved issue, even though it is critical to the understanding o

80 se of this article is to discuss the current issues facing training and workforce in hepatology and p

81 I address these issues first by evaluating the extent to which the resul

82 This is an issue for healthcare organisations seeking to be inclusi

83 spite being recognized as a central clinical issue for RDEB, wound healing impairment has been only m

84 ures have become a topical and controversial issue for the UK National Health Service.

85 trial (Lutein Influence on Macula of Persons Issued From AMD Parents [LIMPIA]) with a 6-month treatme

86 EPC cultures issued from embryos that expressed only wild-type Zeb2 (

87 ietal thiols are key aroma compounds in wine issued from multiple and complex origins.

88 This is a major issue given the technological as well as fundamental imp

89 ttractive approach to address water scarcity issues globally.

90 The WHO issued guidelines for DBAN after it was linked with canc

91 Since the issue has been tackled almost exclusively by macroscopic

92 rgeons and their experiences regarding these issues has not previously been performed.

93 SYNTHESIS: We identified four issues highlighting the key areas of ethical tension cen

94 In this issue, Hosoi et al. find that loss of VDAC2 diverts BAK

95 To address issues identified with existing methods, we developed GB

96 st report published in the 2014 NAR Database Issue, IMG/M's dataset content has tripled in terms of n

97 We studied this issue in a large prospective cohort study.

98 nsion of the serum half-life is an important issue in developing new therapeutic proteins and expandi

99 unveiling the challenging surface chemistry issue in Li-S batteries.

100 We address this issue in the context of adaptation to walking on a split

101 s are cleared, but it becomes a more complex issue in the context of persistent infections.

102 lmonella is still an important public health issue in the whole world.

103 A major issue in thermochronology and U-Th-Pb dating is the effe

104 under which more than 600,000 licenses were issued in the first year of implementation in 2015 alone

105 MOFs remains a challenge for addressing key issues in catalysis, for example, the efficiency of cata

106 stitutions working on climate-related health issues in low- and middle-income countries need to conti

107 onsiderable promise in elucidating important issues in plant domestication and in agricultural origin

108 The work raised issues in the phenomenon of reference in this domain and

109 ces in social cognition are a long discussed issue, in particular those concerning Theory of Mind (To

110 These issues include the selection of appropriate Treg subsets

111 However, Symlin still has some issues including solubility, oral bioavailability and co

112 nvestigations have revealed several emerging issues, including new populations at risk because of tra

113 ts and the main turbulence variables of jets issued into a vegetated channel flow.

114 s study presents and analyzes turbulent jets issued into an obstructed cross-flow, with emergent vege

115 Our model illustrates many of the issues involved in testing and validating urban simulati

116 Lowering device voltage to avoid this issue is hindered by an inadequate understanding of the

117 One promising technology to address this issue is in situ healing of compromised membranes via he

118 In Africa this issue is of primary importance, but the agreement betwee

119 This issue is particularly relevant in supported bimetallic s

120 At issue is the merits of intervention modalities, such as

121 In addition to known developmental issues, it is thus likely that some dysfunction is also

122 sing microarrays, but considerable technical issues limit current CNA calling based upon DNA sequenci

123 he development of a simple solution to these issues: manipulating Cu(I) --> Cu(II) oxidation and expl

124 In this issue, Muller and Nieduszynski find that early replicati

125 In this issue, Nabet et al. demonstrate that dynamic feedback be

126 In this issue, Nelson and colleagues (2017) determined that guan

127 In this issue of Cancer Cell, Chen et al. describe complementary

128 In this issue of Cancer Cell, Justilien et al. report that Ect2

129 In this issue of Cancer Cell, Mina et al. systematically charact

130 In this issue of Cancer Cell, Spranger et al. indicate that chem

131 In this issue of Cancer Cell, Todoric et al. discover a role for

132 In this issue of Cancer Cell, Vila et al. report that UBE2O, a u

133 In this issue of Cancer Research, Vivian and colleagues utilize

134 In this issue of Cell Host & Microbe, Danne et al. (2017) report

135 In this issue of Cell Host & Microbe, Moguche et al. (2017) show

136 In this issue of Cell Host & Microbe, Raaben et al. (2017) ident

137 In this issue of Cell Host & Microbe, Tegtmeyer et al. (2017) sh

138 In a recent issue of Cell Host & Microbe, Thiemann et al. (2017) rep

139 In this issue of Cell Host & Microbe, Yuan et al. (2017) show th

140 l and Tiyaboonchai et al. (2017) in a recent issue of Cell Reports utilize hPSCs to characterize GATA

141 Shi et al. (2017) in this issue of Cell Stem Cell and Tiyaboonchai et al. (2017) i

142 In this issue of Cell Stem Cell, Chen et al. (2017) delineate an

143 In this issue of Cell Stem Cell, Forrest et al. (2017) demonstra

144 In this issue of Cell Stem Cell, Kee et al. (2017) and Kirkeby e

145 In this issue of Cell Stem Cell, Miura and Suzuki (2017) describ

146 In this issue of Cell Stem Cell,Lee et al. (2017) report prospec

147 In this issue of Cell, Hulsmans et al. identify a subset of macr

148 In this issue of Cell, insights from a longitudinal multi-omics

149 In this issue of Cell, Roe et al. show that metastatic progressi

150 In this issue of Cell, Rusu et al. demonstrate that a cluster of

151 In this issue of Cell, Yu et al. add to these findings by identi

152 with particular emphasis on the challenging issue of designing materials that selectively adsorb the

153 In this issue of Developmental Cell, Bulusu et al. (2017) and Og

154 In this issue of Developmental Cell, Dickinson et al. (2017) and

155 Reporting in this issue of Developmental Cell, Pae et al. (2017) show that

156 In this issue of Developmental Cell, Roh-Johnson et al. (2017) r

157 ith prematurity and reduced fetal growth, an issue of further interest given the mounting evidence th

158 In this issue of Genes & Development, Dewar and colleagues (pp.

159 In this issue of Genes & Development, Uyehara and colleagues (pp

160 In this issue of Genes & Development, Zhu and colleagues (pp. 14

161 Allergy is a public health issue of high socioeconomic relevance, and development o

162 In this issue of Immunity, Liew et al. (2017) reveal a critical

163 In this issue of Immunity, Riffelmacher et al. (2017) show that

164 In this issue of Immunity, Shan et al. (2017) highlight that eff

165 In this issue of Immunity, Spath et al. (2017) show that the dys

166 In this issue of Immunity, Van Braeckel-Budimmir et al. (2017) r

167 In this issue of Immunity, Zhu et al. (2017) report that tumor-a

168 In this issue of JEM, Bergman et al. challenge the data publishe

169 In this issue of JEM, Deniset et al. provide new data that exten

170 In this issue of JEM, Marciniak et al. identify a putative novel

171 In this issue of Molecular Cell, Chao et al. (2017) investigate

172 In this issue of Molecular Cell, Legnini et al. (2017) and Pamud

173 In this issue of Molecular Cell, Nielson et al. (2017) character

174 In this issue of Molecular Microbiology, Rued et al. show that i

175 In this issue of Neuron, Beattie et al. (2017) use elegant MADM-

176 In this issue of Neuron, Ben-Yaacov et al. (2017) dissect the in

177 In this issue of Neuron, Chu et al. (2017) show that dopamine de

178 In this issue of Neuron, d'Ydewalle et al. (2017) devise a new w

179 In this issue of Neuron, Gasset-Rosa et al. (2017) and Grima et

180 In this issue of Neuron, Ishiguro et al. (2017) explore the toxi

181 In this issue of Neuron, Mandelblat-Cerf et al. (2017) show that

182 In this issue of Neuron, Padamsey et al. (2017) demonstrate that

183 In this issue of Neuron, Wang et al. (2017) show that alpha2delt

184 ction, just a few studies have addressed the issue of odor coding on top of continuous odorous backgr

185 echanism solves the inherent cross-diffusion issue of redox ECs and has the added benefit of greatly

186 However, in a recent issue of Science, Al Jord et al. (2017) show that key re

187 In a recent issue of Science, Bardina et al. (2017) explore the prot

188 allization of perovskites and addressing the issue of slow electron extraction.

189 The issue of the aging physician and when to cease practice

190 Two studies in this issue of the JCI use a humanized mouse model and demonst

191 In this issue of the JCI, Ando et al. provide a causal link betw

192 In this issue of the JCI, Burnett and colleagues used a comprehe

193 In this issue of the JCI, Kedves and colleagues report the ident

194 In this issue of the JCI, Lu and colleagues asked whether the re

195 In this issue of the JCI, McKee and colleagues use a laminin pol

196 In this issue of the JCI, Perry and colleagues provide evidence

197 In this issue of the JCI, Shin and colleagues report that SOHLH1

198 In this issue of the JCI, Van de Bittner and colleagues describe

199 In this issue of the JCI, Wang and coworkers show that glutamate

200 In this issue of the JCI, Zhang and colleagues show that the car

201 In this issue of the Journal of Clinical Microbiology, Truong et

202 emase activity in Enterobacteriaceae In this issue of the Journal of Clinical Microbiology, V.

203 In this issue of the Journal, Pace et al.:1115-1124) clearly doc

204 In this issue of the Journal, Schmid et al identify Spondin 2 (S

205 In a paper published in the September 1979 issue of the Journal, then study director William Kannel

206 re owing in part to the unique developmental issues of adolescents and young adults as well as the co

207 future technology directly addressing global issues of atmospheric CO2 balance.

208 We then discuss issues of design choice, highlighting power and feasibil

209 new and established databases deal with the issues of human health, from cancer-causing mutations to

210 epidemiologic literature is focusing beyond issues of internal validity and turning its attention to

211 To date, much of this has been hindered by issues of sample preparation and assay signal-to-noise.

212 ning and enables ligand evolution to address issues of selectivity and reactivity.

213 d challenges due to difficulties in handling issues of statistical reliability and robustness, often

214 been optimized in order to overcome all the issues of the technological integration.

215 In this issue Ohsaki et al. explain how breastfeeding can preven

216 plans to address allergy as a public health issue ought to be on national and regional agendas.

217 In order to address this issue, our paper presents, for the first time, the integ

218 In this issue, Overacre-Delgoffe et al. show that interferon gam

219 ldhood development (ECD) remains a neglected issue, particularly in resource-poor countries.

220 s covariables were Knowledge of Survivorship Issues, Perceived Efficacy in Patient-Physician Interact

221 In this issue, Perez-Mockus et al. report that a subset of Sdt i

222 In this issue, Pontes et al. shed new light on how the interplay

223 n social groups dealing with truth statement issues present mixed findings on the conditions of truth

224 brain injury (TBI) is a major public health issue, producing significant patient mortality and poor

225 This issue provides a clinical overview of atrial fibrillatio

226 We reflect on the major issues raised by a thoughtful and diverse set of comment

227 Although the issues raised in the report were hardly novel, they gave

228 Issues regarding incorrect apparent order of deposition

229 antibodies, many bispecific antibodies have issues regarding production, stability, and pharmacokine

230 aced in the context of previously unresolved issues related to BDNF biology, as well as how BDNF may

231 medical costs (>/= 10% of annual income) and issues related to financial burden (jeopardizing care or

232 e of this article is to explore core ethical issues related to physician-assisted suicide and euthana

233 apping and mutually exclusive paths, several issues related to RNA recruitment remain.

234 rovides information on potentially important issues related to the off-label treatment approach that

235 of integrative taxonomy has not been without issue, revealing challenges that must be considered when

236 lications of fatty acid-conjugation, several issues should be addressed, including a poor solubility

237 igh temporal and spatial resolution, in this issue, Simoes et al. reveal that myosin-driven anisotrop

238 therapy due to the potential for overcoming issues such as drug resistance.

239 ograms requires the consideration of several issues such as HIPAA, state and local licensure requirem

240 rised or have stability or batch variability issues, supporting the use of alternative binding protei

241 te for large-scale solar energy storage, but issues surrounding the efficiency and the stability of p

242 ds to individual biomedical profiles and the issues surrounding them.

243 line is able to enrich the debate on medical issues, thanks to many philosophical currents such as de

244 zebrafish constitutes a complicated ethical issue that calls for the exploration of alternative test

245 Sepsis is a prevalent health issue that can lead to central nervous system (CNS) infl

246 To address the issue that deep probabilistic graphical models requires

247 lity of rechargeable metal-air batteries, an issue that is gaining increasing interest in recent year

248 kite solar cells (PSCs); however, suffer the issue that lead is toxic to the environment and organism

249 This demonstration of the quantitative issues that arise in transporting effects between popula

250 study raised important environmental justice issues that can inform public health programs and wildfi

251 ominent autoimmune pathways and identify key issues that require resolution for full understanding of

252 be key to investigating numerous fundamental issues that thus far have remained experimentally inacce

253 ttings and applied to a global public health issue, the polio eradication Endgame plan.

254 To highlight the importance of this issue, the present study investigated the long-term impa

255 the data-imbalance and location-correlation issues, the GLMM effectively quantified true biological

256 leadless devices have addressed some of the issues, their pacer-integrated batteries cause new healt

257 tention and the clinical significance of the issue, this article analyzes the assumptions of the theo

258 To circumvent these issues, this study describes a new way of increasing pro

259 In this issue, three different studies provide complementary per

260 ective filtering and suffer from scalability issues, thus are not well-suited for realistic genome-sc

261 s has traditionally been considered to be an issue to be addressed separately from the physical radio

262 Food safety is a major issue to protect public health and a key challenge is to

263 idualized communication coaching to identify issues to address during an upcoming oncologist visit.

264 In this issue, two studies examine the extent to which variation

265 To combat these issues, typically material properties are adjusted, but

266 Here, we addressed this issue using a Treg fate-mapping approach, which revealed

267 de, Caenorhabditis elegans, to explore these issues using three chemical-free specimen preparations:

268 around a smartphone and which does not face issues usually common to reusable sensors.

269 The multiple response issue was also carefully addressed.

270 To address this issue we developed OncoScore, a text-mining tool that ra

271 To address this issue, we carried out 60x whole-genome sequencing of 26

272 To address this issue, we conducted a systematic single-particle EM stud

273 Here, to test potential solutions to this issue, we design and analyse a CRISPR-Cas9 library with

274 To address this issue, we developed a nanoparticle based platform, calle

275 To address this issue, we developed an ITC empirical response model (ITC

276 To address this issue, we fabricated protein-decorated graphene FETs and

277 To further address this issue, we generated Sco1hrt/hrt and Sco1stm/stm mice in

278 To resolve this issue, we have scrutinized cryo-electron tomograms of ra

279 power while addressing the multiple testing issue, we implement filters to remove data sets where th

280 To address this issue, we introduce a novel approach for multi-modal co-

281 To address this issue, we investigated the folding preferences of oligon

282 To address this issue, we present pgRNAFinder, with an easy-to-use web i

283 To address this issue, we sought to reproduce the nonrandom features of

284 To clarify this crucial issue, we studied 87 human participants of both sexes du

285 To address this issue, we studied ATP requirement in three typical forms

286 To examine this issue, we used single glomerular stimulation in mouse ol

287 To overcome these issues, we provide techniques and algorithms for image p

288 In this issue, Webb et al. show that the liver-specific isoform

289 To address such issues, well-designed yolk-shelled carbon@Fe3 O4 (YSC@Fe

290 No significant safety issues were observed in any treatment group.

291 No new or unexpected safety issues were reported for either treatment in this study

292 concept suffers from a number of logistical issues when considering its construction in vivo.

293 se gestural enrichments are typically not at-issue, whereas iconic enrichments in sign language can o

294 Resolving these three issues will lead to better, more replicable, and more us

295 An emerging issue with these drugs is that most cause hypertension.

296 This approach enabled us to diagnose an issue with TXS solubility, the resolution of which yield

297 pment of IBV vaccines.IMPORTANCE A number of issues with regard to the effectiveness of the LAIV vacc

298 We show that potential methodological issues with the WCS do not corrupt information-theoretic

299 is one of the major issues within the avocado supply chain.

300 ocess termed "phagosome maturation." In this issue, Yin et al. identify GOP-1 as essential for the ma