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1 get in each individual (i.e. the critical AT isthmus).
2 med at the pulmonary vein and cavo-tricuspid isthmus.
3 al of most midbrain/hindbrain cells near the isthmus.
4 71%) had an identifiable endocardial circuit isthmus.
5 t mapping overestimates the true size of the isthmus.
6 tified to attempt to trace the course of the isthmus.
7 ding projections beyond the diencephalon and isthmus.
8 lbumin+ labeling, is observed in the ventral isthmus.
9 ed in the tricuspid annulus-eustachian ridge isthmus.
10 stal Plain and the tropical Central American Isthmus.
11 neurons project anterodorsally to enter the isthmus.
12 n guiding ablation within the cavo-tricuspid isthmus.
13 was consistent with entrainment criteria for isthmus.
14 ent by mapping to identify a reentry circuit isthmus.
15 s quiescent stem cells in the gastric corpus isthmus.
16 specificity for identifying the clinical VT isthmus.
17 mic isthmuses containing VT re-entry circuit isthmuses.
19 s action potential duration alternans at the isthmus (11 of 20 patients) and 2:1 isthmus conduction b
23 ength, 3.9+/-1.08; thickness, 1.5+/-0.3 cm), isthmus 1B intermediate dimensions (mean length, 2.4+/-0
25 th, isthmuses 1A and 1B were present in 88%, isthmus 2 in 25%, isthmus 3 in 94%, and isthmus 4 in 13%
26 th, 2.4+/-0.8; thickness, 1.1+/-0.4 cm), and isthmuses 2, 3, and 4 the smallest dimensions (mean leng
27 ) was significantly shorter than the central isthmus (24 mm +/- 4.3; range, 12-43 mm) and the central
28 l isthmus was shorter than the inferolateral isthmus (27 mm +/- 4.8; range, 13-45 mm) (P < .001).
33 cava isolation in 6 patients, cavotricuspid isthmus ablation in 5 patients, and ablation of sites of
36 block were thoroughly reviewed in 271 mitral isthmus ablation procedures undertaken among 236 patient
38 Among the 105 patients who did not undergo isthmus ablation, 25 patients (24%) were documented to h
39 on was performed followed by roof and mitral isthmus ablation, before CFAE ablation in the CFAE arm.
47 e (skeletonized) geometric parameters of the isthmus and border zone were measured from the maps.
48 e show that Gli3 regulates patterning of the isthmus and cerebellar anlage by confining Fgf8 expressi
49 and E11.0, Gli3 continues to be required for isthmus and cerebellum development, but primarily for de
51 or establishing a distinct posterior tectum, isthmus and cerebellum, but does not play a role in the
52 deling studies recapitulated DEEPs at the VT isthmus and demonstrated their role in VT initiation wit
53 on (CI) was performed incorporating putative isthmus and early exit site(s) based on standard criteri
54 ction potentials (MAPs) were recorded at the isthmus and either high or low right atrium (HRA, LRA) d
55 ontractions of the muscles in the pharyngeal isthmus and function systemically to regulate an enhance
58 procedural success (transection of anatomic isthmus and noninducibility) and freedom of VT recurrenc
63 ppeared to be differentiating neurons in the isthmus and the rostral hindbrain region, including the
64 he projection of trochlear axons towards the isthmus and their subsequent growth within that tissue m
65 s this, we conditionally ablated Fgf8 in the isthmus and uncovered that prolonged expression of Fgf8
68 r anlage by confining Fgf8 expression to the isthmus, and attenuates growth of dorsal r1 (before E11.
70 secondary gustatory/visceral nucleus in the isthmus, and for distinguishing territories in the prima
71 ng for the loss of brain structures near the isthmus, and instead demonstrate that tissue transformat
73 regions such as the midbrain tectum, dorsal isthmus, and motor nuclei, ASP and GABA immunoreactivity
74 m body, anterior midbody, posterior midbody, isthmus, and splenium) and for overall CC size, with lef
75 pital fasciculus, internal capsule, callosal isthmus, and the corona radiata (p=0.04 for FIQ and p=0.
77 es that target both scar-related and classic isthmuses appear necessary to prevent long-term recurren
78 targeted deletion of PPARgamma in the bulge/isthmus area of the hair follicle epithelium generates a
79 iculum of the isthmus (PaSi), area 29 of the isthmus (area 29i) and area prostriata (Pro), which has
80 6 of the 19 patients, a total of 41 distinct isthmus areas of 41 distinct VTs were identified and suc
81 in comparison with controls, although aortic isthmus/arterial duct diameter ratio was lower in fetuse
83 8 signaling from the mid/hindbrain boundary (isthmus) as being responsible for induction of different
84 part of the cingulum and the cingulate gyrus isthmus, as well as the precuneal GM, may be distinctive
86 ngeal muscles and marginal cells forming the isthmus between the anterior and posterior pharyngeal bu
87 accharomyces cerevisiae they localize at the isthmus between the mother and the daughter cells, where
89 asured the conduction time, CTi, through the isthmus between the tricuspid annulus and eustachian rid
90 sal r1 (before E11.0) and the dorsal mes and isthmus (beyond E11.0) through regulation of cell prolif
93 is study evaluates the long-term efficacy of isthmus block for treatment of re-entry VT in adults wit
94 dered a reliable criterion of cavo-tricuspid isthmus block in patients undergoing radiofrequency abla
95 ed RA maze procedure is superior to anatomic isthmus block in treating reentrant AT in postoperative
99 uch-up lesions was necessary to complete the isthmus block with conventional fluoroscopy (median, thr
100 ictors for unsuccessful bidirectional mitral isthmus blockade were the need for epicardial ablation f
101 cardiomyopathy, obliteration of a conductive isthmus both anatomically and functionally and abolition
103 l in which Wnt regulates FGF activity at the isthmus by driving both FGF and Sprouty gene expression.
109 Atrophy in mesial and lateral temporal, isthmus cingulate, and orbitofrontal areas aided discrim
111 , across Beringea, and across the Panamanian isthmus coincide in timing and location with multiple we
112 00% of patients when the RF line included an isthmus compared with 53% when RF had to be guided by pa
113 s at the isthmus (11 of 20 patients) and 2:1 isthmus conduction block immediately preceding AF (4 of
118 ena cava, crista terminalis, tricuspid valve isthmus, coronary sinus orifice, membranous fossa ovalis
119 ow-up, WM volume in the left cingulate gyrus isthmus correlated with clinical scores of anxiety (Spea
120 m of the study was to determine whether a VT isthmus could be identified and followed by pace mapping
121 AJ disconnection combined with cavotricuspid isthmus (CTI) ablation (group 1, n=49) or PV-LAJ disconn
123 or scar-dependent (n = 15) and cavotricuspid isthmus (CTI)-dependent (n = 14) flutter were studied.
124 al fibrillation may experience cavotricuspid isthmus (CTI)-dependent atrial flutter during follow-up.
125 the surface expression of non-cavotricuspid isthmus (CTI)-dependent right atrial (RA) or left atrial
128 sthmus-dependent (CWID) and counterclockwise isthmus-dependent (CCWID) right atrial flutter (AFL) and
129 ve) morphology among patients with clockwise isthmus-dependent (CWID) and counterclockwise isthmus-de
131 tra-atrial re-entrant tachycardia (IART) and isthmus-dependent atrial flutter (IDAF) in patients pres
133 t atrial tachycardias included cavotricuspid isthmus-dependent atrial flutter (n=7), non-isthmus-depe
134 us-dependent atrial flutter (IDAFL) from non-isthmus-dependent atrial flutter (NIDAFL) from the elect
135 rial tachycardia was seen in 7 patients, and isthmus-dependent atrial flutter occurred in 14 patients
136 ring 66 ATs in 62 patients: 20 cavotricuspid isthmus-dependent ATs, 20 perimitral ATs, 13 focal ATs w
140 ight AFL is most commonly associated with an isthmus-dependent mechanism (ie, LLR or subeustachian is
141 ease with preserved ventricular function and isthmus-dependent re-entry, VT isthmus ablation can be c
142 isthmus-dependent atrial flutter (n=7), non-isthmus-dependent right atrial reentry (n=7), and 1 foca
143 ardias were macroreentrant (noncavotricuspid isthmus-dependent), and 35 ATs were focal (either trigge
144 -macro-re-entrant (perimitral, cavotricuspid isthmus-dependent, and roof-dependent circuits) versus c
145 t to determine whether the atrial flutter is isthmus-dependent, non-isthmus-dependent, or atypical; (
146 the atrial flutter is isthmus-dependent, non-isthmus-dependent, or atypical; (2) interrupting the atr
150 est: the optic tectum, torus semicircularis, isthmus, dorsal and medial nuclei of the octavolateral a
151 size that HSPGs are necessary for pharyngeal isthmus elongation, and pyr-1 functions upstream of prot
152 t pyr-1(cu8) exhibiting defective pharyngeal isthmus elongation, cytoskeletal organization defects, a
153 ansion and the repolarizing cells within the isthmus enabled retrograde flow of depolarizing electrot
154 ere slowest at the inward curvature into the isthmus entrance (0.28+/-0.2 m/s), slightly faster at th
155 h gastric mucus neck cells located below the isthmus express trefoil factor family 2 (TFF2) protein,
156 blation has been used to target the critical isthmuses for re-entrant monomorphic ventricular tachyca
158 rom initial experiments, correctly predicted isthmus geometry (mean estimated/actual isthmus overlap
160 th pacing threshold (r=0.64, P<0.0001), many isthmuses had very low-amplitude electrograms, and EUS c
161 ing and the relationship to the protected VT isthmus identified by entrainment mapping is unknown.
162 sful ablation sites were localized within an isthmus identified by pace mapping in all of these 10 pa
163 ed in the MI region either through a circuit isthmus identified from entrainment mapping or a target
164 ed by pace mapping (P=0.0002); those with an isthmus identified received shorter ablation lines (4.9+
167 ed RFCA for VTs dependent on septal anatomic isthmuses improves ablation outcome in repaired Tetralog
169 lopment and becomes restricted mainly to the isthmus in adult glands, akin to its known localization
170 ured at 90% repolarization was longer at the isthmus in all patients, and failed to shorten with rate
172 ombined mapping approach identified a narrow isthmuses in the lateral atrium, where the first RF lesi
173 ) in repaired Tetralogy of Fallot focuses on isthmuses in the right ventricle but may be hampered by
178 ss ablation is required if a reentry circuit isthmus is identified even when multiple and unstable VT
179 timing of dispersal or vicariance across the Isthmus is not explained by the ecological factors teste
180 whereas the absence of Gly-ir neurons in the isthmus is shared by all these species, except for lampr
182 hin the tricuspid annulus-inferior vena cave isthmus (IS) and either side of the crista terminalis (C
189 ary vein isolation in 50 (100%), left atrial isthmus line in 47 (94%), anterior line in 45 (90%), com
191 essment of bidirectional block across mitral isthmus linear lesion using differential coronary sinus
192 round the left septum primum with a critical isthmus located between the pulmonary veins posteriorly
196 progressive pacing first caused alternans of isthmus MAP duration and amplitude at mean cycle length
197 potential duration rate maladaptation at the isthmus may lead to action potential duration alternans
199 ed by entrainment exceeded dimensions of the isthmus measured by activation mapping by 32+/-18%.
202 n strategies, ablations of the cavotricuspid isthmus (n=4), fossa ovalis (n=4), and pulmonary veins (
205 d BZ channels identified 74% of the critical isthmus of clinical VTs and 50% of all the conducting ch
206 gene Axin2, is limited to the base and lower isthmus of gastric glands, where the stem cells reside.
210 des occurred at 4.90 Ma, indicating that the Isthmus of Panama allowed genetic exchange until the Pli
211 he linking of North and South America by the Isthmus of Panama had major impacts on global climate, o
214 reater connectivity in the posterior midbody/isthmus of the corpus callosum and that fractional aniso
215 ed that diffusion anisotropy in the body and isthmus of the corpus callosum was negatively correlated
216 on, and diffusion anisotropy in the body and isthmus of the corpus callosum was shown to mediate this
220 a before the first humans crossed the Bering Isthmus or the onset of climate changes during the termi
221 ck in the tricuspid annulus-eustachian ridge isthmus or was associated with development of transient
222 cy results in reduced Fgf8 expression in the isthmus organiser (IsO), an embryonic signalling centre
226 of the isthmus (PrSi), parasubiculum of the isthmus (PaSi), area 29 of the isthmus (area 29i) and ar
229 ing have no defects in pharyngeal pumping or isthmus peristalsis rates, but their growth defect depen
230 t of the two motions were distinct, but each isthmus peristalsis was coupled to the preceding pump.
240 nce of lmx1b.1 and lmx1b.2 expression at the isthmus requires the function of no isthmus/pax2.1, as w
242 cond ablation was performed either along the isthmus (scar-dependent group) or from the scar to anoth
243 nus rhythm, pace mapping near the exit of an isthmus should produce a QRS similar to that of VT.
244 encephalon, diencephalon, mesencephalon, and isthmus showed some deviation from the main scheme.
245 pping data were analyzed from the identified isthmus site and from sites at progressively increasing
249 Radiofrequency ablation was performed at isthmus sites as defined by pace-mapping (perfect pace-m
250 was to identify ventricular tachycardia (VT) isthmus sites by pace-mapping within scar tissue and to
257 ting of two wide regions connected by a thin isthmus.Structural heterogeneities provided a substrate
258 at inferior levels and the midbrain-pontine isthmus suggests a vulnerable region of passage for comp
259 on standard characterization of suspected VT isthmus surrogates thus limiting ablation target size.
260 preoptic area, ventral hypothalamus, nucleus isthmus, tectum mesencephali, inferior colliculus, and h
261 on in the isthmus between the TA and IVC (TI isthmus) terminated the tachycardia in all patients.
263 halamus, the habenula, the optic tectum, the isthmus, the cranial motor nuclei, and the spinal motor
266 tionship of the ventricular tachycardia (VT) isthmus to channels of preserved voltage on an electroan
269 ft side, and (3) left-sided RFCA resulted in isthmus transection and prevention of VT induction.
272 epted date of 3 million years ago (Ma), the Isthmus was effectively complete by the middle Miocene,
274 hermore, 22 of the 81 VTs (27%) for which no isthmus was identified became noninducible after ablatio
277 mm +/- 4.3; range, 12-43 mm) and the central isthmus was shorter than the inferolateral isthmus (27 m
279 e posterior left atrium and along the mitral isthmus, was performed under the guidance of an electroa
281 Conduction velocities within the shared isthmus were dependent on the activation vector, consist
288 Fgf8 expression normally correlates with the isthmus where cells undergo low proliferation and that i
290 in positioning the mid/hindbrain organizer (isthmus), which regulates midbrain and cerebellar develo
291 nd (2) targeted illumination of the critical isthmus, which was identified via analysis of simulated
292 dorsal projection, which circumnavigates the isthmus, while those of more posterior trochlear neurons
293 hibchan speakers on both sides of the Panama isthmus, who have ancestry from both North and South Ame
295 age channels with ILPs harbored the clinical isthmus with a sensitivity and specificity of 78% and 85
298 ally complex structures, particularly at the isthmus, with substrate for multiple VT morphologies aft
299 2 minutes) were formed at the cavo-tricuspid isthmus, with the end point of bidirectional block.
300 WM bilaterally and the left cingulate gyrus isthmus WM, as well as the right precuneal GM, showed si
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