ライフサイエンスコーパス: it is difficult to

1 Although it is difficult to accomplish in the human host, longitudinal

2 However, a major limitation of short-read data is that it is difficult to accurately predict full-length splice isof

3 management is critical to maintaining glycemic control, yet it is difficult to achieve due to the high individual differe

4 te-selectivity with designed transition-metal catalysts but it is difficult to achieve exceptionally high levels of site-

5 ven cell type are also more likely to be promoter-proximal, it is difficult to assess whether motifs identified in that s

6 For many zoonotic diseases it is difficult to attribute human cases to sources of infect

7 imulation, and the ensuing mechanisms for their production, it is difficult to attribute specific functions as drivers or

8 omologous, these PE/PPEs are very challenging to study, and it is difficult to be certain what role(s) they have in the p

9 However, it is difficult to check for any bias in the peer-review proc

10 we find that many diversification shifts occur after WGDs, it is difficult to consider diversification and duplication t

11 gment propagation are not well understood, however, because it is difficult to control for confounding factors such as ho

12 delivery remains a challenge in cancer precision medicine; it is difficult to deliver a targeted therapy to cancer cells

13 However, because PEL is highly multi-dimensional it is difficult to describe how the system moves around in PE

14 Given their size it is difficult to detect and visualize the presence of NPs i

15 ever, when two Y-STR haplotypes have a few mismatched loci, it is difficult to determine if they are from the same male l

16 Based on traditional morphological characters, it is difficult to differentiate these two genera.

17 le, in cell culture models of alpha-syn-seeded aggregation, it is difficult to discern intracellular from extracellular e

18 However, in such studies, it is difficult to disentangle the effects of nutrient supply

19 e have decreased substantially over the last 3 decades, but it is difficult to disentangle what effects individual innova

20 lex interactions between various cells in AD inflamed skin, it is difficult to dissect the precise and multiple roles of

21 lly invasive surgery has been extended to neonatal surgery, it is difficult to establish its role for neonatal disorders

22 One major challenge to studying LRP1 has been that it is difficult to express such a large, highly glycosylated,

23 changes in the geographic arrangement of continental crust, it is difficult to identify a specific causal mechanism.

24 Since oxygenation and respiratory mechanics are linked, it is difficult to identify which variables, pressure or oxyg

25 As a result, it is difficult to infer cause or predict future trajectories

26 h humans have cospeciated with their gut-resident microbes, it is difficult to infer features of our ancestral microbiome

27 However, it is difficult to interpret the results at the early stages

28 Whereas previous studies suggest it is difficult to maintain attention and vigilance over long

29 Without these data, it is difficult to make informed regional or national policy

30 However, it is difficult to measure the volume of the hard or soft pha

31 However, it is difficult to observe these dynamics directly over long

32 However, it is difficult to obtain quantitative data from microscopy a

33 Because of cell to cell variation, it is difficult to obtain statistically significant data on t

34 This smoothness is also the reason that it is difficult to precisely determine the transition point e

35 or identical sequence motifs, such as G-boxes (CACGTG), so it is difficult to predict regulatory relationships.

36 However, it is difficult to predict their properties based on macrosco

37 Given this apparent complexity, it is difficult to predict where, when, or even whether cross

38 onents contribute to the signal in a single pixel, however, it is difficult to quantify their individual contributions an

39 However, it is difficult to quantitatively compare the efficacy of pep

40 However, it is difficult to reconcile network complexities with a form

41 well as population structure between geographic localities, it is difficult to resolve markers that segregate entirely be

42 In addition, we show here that it is difficult to resolve subcortical sources because distri

43 h many high-quality aptamers have been previously reported, it is difficult to routinely generate aptamers that possess b

44 However, it is difficult to scale down the size of these instruments d

45 allenge for the conventional targeted analytical assays, as it is difficult to screen for "unknown" compounds.

46 This is especially useful in species where it is difficult to study social traits in natural populations

47 Because at present it is difficult to tell where sign stops and gesture begins,

48 However, it is difficult to test these ideas in natural ecosystems, wh

49 embly of axon initial segments (AISs) and nodes of Ranvier, it is difficult to uncouple their roles in maintaining axon i

50 hat it is going to rain, I will take an umbrella-therefore, it is difficult to understand their interplay.