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4 nance of contractile endurance in rat muscle it is unknown whether a similar regulation exists in hum
7 abdominal fat mass before pregnancy because it is unknown whether abdominal fat mass, independently
8 ated with health outcomes and mortality, yet it is unknown whether accounting for SES can improve ris
12 equivalent to those with cuticular suturing, it is unknown whether adhesive strips provide additional
20 are impaired in most psychiatric disorders, it is unknown whether alterations in the dopamine system
21 MDmc projects to areas in addition to pOFC, it is unknown whether amygdalar pathways in MDmc innerva
23 tenin have been well characterized; however, it is unknown whether and how a deubiquitinase is involv
24 s, and while specific peaks can be favoured, it is unknown whether and how early a commitment to fina
26 buted semantic processing network [4-6], but it is unknown whether and how individual neurons in the
27 h PAM recognition is essential for cleavage, it is unknown whether and how PAM binding activates Cas9
31 ate memory-forming hippocampal synapses, yet it is unknown whether (and how) these hormones interact
32 nocular information for computing 3D motion, it is unknown whether (and how) these two signals intera
41 nst RPCs might develop and induce RPC death, it is unknown whether autoantibodies against cell-surfac
43 rlying mechanisms are poorly understood, and it is unknown whether autophagy affects only whether or
44 esize BChl e but accumulate BChl c; however, it is unknown whether BciD is sufficient to convert BChl
45 pression and antidepressant action, although it is unknown whether BDNF and TrkB in the dorsal raphe
47 to suppress VLDL production from the liver, it is unknown whether brain insulin signaling independen
50 may enter the tricarboxylic acid cycle, but it is unknown whether catabolic by-products of the GABA
51 will be tumor-associated Ag (TAA) specific, it is unknown whether CD8(+) T cells with specificity fo
52 ce embryos die before the first HSCs emerge, it is unknown whether Cdh5 has a direct role in HSC emer
53 hythms are vital to human mental health, but it is unknown whether circadian rhythms "entrained" to t
58 eficits and alpha-syn accumulation; however, it is unknown whether combining humoral and cellular imm
59 are conserved throughout the animal kingdom, it is unknown whether common signaling pathways regulate
60 er SCI in association with axons and myelin, it is unknown whether complement proteins affect axon gr
69 heir neighbouring membrane proteins, however it is unknown whether different membrane protein propert
71 ed risk of adverse health outcomes; however, it is unknown whether discrimination is related to incid
72 and Epac2 activation can be arrhythmogenic, it is unknown whether distinct subcellular distribution
73 for alloimmune and autoimmune disorders, but it is unknown whether disturbances to T cell immunity ma
76 mmon because of acute myocardial infarction, it is unknown whether early coronary angiography is asso
78 associated with disorders in childhood, but it is unknown whether effects persist into adulthood.
79 omatic cells has been demonstrated, however, it is unknown whether electrophysiologically-active soma
83 improve S(I) in obese individuals; however, it is unknown whether exercise and RYGB surgery-induced
86 icator bacteria in urban coastal waters, but it is unknown whether exposure to seawater after rainsto
89 synapses of cones and other retinal neurons, it is unknown whether Gbetagamma contributes to these ef
91 eratinocytes is incompletely understood, and it is unknown whether glycolytic regulation is essential
92 sclerotic cardiovascular disease (CVD) risk, it is unknown whether guidelines can identify HIV-infect
98 cytokine production in response to PGD2, but it is unknown whether ILC2s are active in patients with
100 ve pathway, is impaired in pancreatitis, but it is unknown whether impaired autophagy is a cause or a
105 adult tissues, enhancers lack H3K27me3, and it is unknown whether intergenic H3K27me3 deposits affec
106 ibed in maturing mammalian granulocytes, but it is unknown whether IR occurs broadly in other hematop
109 ry response is promptly activated after TBI, it is unknown whether it has a significant role in chron
112 instruct map formation in sensory circuits, it is unknown whether it plays a role in the organizatio
113 rgic signaling alters histone modifications, it is unknown, whether it also affects other epigenetic
120 rosis (ALS) and frontotemporal dementia, but it is unknown whether loss of function, toxicity by the
122 is shaped by localized growth responses, but it is unknown whether LPS influences these responses in
124 ssential role in auditory fear conditioning, it is unknown whether LTP is induced selectively in the
126 inhibiting the mitochondrial complex I, but it is unknown whether manassantin inhibits mitochondrial
133 to mucosal-associated invariant T cells, but it is unknown whether MR1 can present alternative antige
134 tumours expressing highly stabilized mutp53, it is unknown whether mutp53 is a therapeutic target in
142 e alcohol drinking in nondependent rats, yet it is unknown whether nicotine facilitates the transitio
143 on by nitric oxide (NO); in plants, however, it is unknown whether NO affects histone acetylation.
145 a mixture of stress-released molecules, yet it is unknown whether or how these interact to mediate t
146 e of host RNAi triggers by pathogenic fungi, it is unknown whether or not such an uptake mechanism ha
149 scription and histone removal in spermatids, it is unknown whether other BET family proteins play a r
151 d clinical adoption of novel anticoagulants, it is unknown whether outcomes differ among patients wit
155 itis associate with cardiovascular risk, but it is unknown whether particular groups of patients have
157 ons are common after major surgery, although it is unknown whether patients achieve improved outcomes
161 requency with which cultural concerns arise, it is unknown whether physician diversity reflects that
162 eby preventing further fertilization events, it is unknown whether plant gametes prevent polyspermy b
163 higher rates of waitlist mortality than men; it is unknown whether practices surrounding delisting fo
164 ent of peripartum cardiomyopathy (PPCM), but it is unknown whether preeclampsia impacts clinical or l
165 However, unlike in oncology or cardiology, it is unknown whether PROs are associated with survival
168 ugh observed in other memory domains [5, 6], it is unknown whether reconsolidation leads to strengthe
170 f postoperative RVOT obstruction and PR, but it is unknown whether relief of the right ventricular vo
171 from inflammation to tissue repair; however, it is unknown whether resolvins play a role in tissue re
173 m for both B cells and epithelial cells, and it is unknown whether serum neutralizing antibodies agai
174 ing acute physiological challenges; however, it is unknown whether sex differences in LV mechanics ar
175 AMPARs in artificial expression systems, but it is unknown whether Shisa7 has a functional role in gl
176 itical regulator of metabolism in the liver, it is unknown whether SHP is necessary to coordinate met
180 ength and when localized onto particles, but it is unknown whether spatial localization of short-chai
181 s has not been studied for the H3R; further, it is unknown whether splice variants of the same recept
186 owever, in most higher-order cortical sites, it is unknown whether such M-P streams exist and/or what
190 cromolecules between these compartments, but it is unknown whether surveillance mechanisms exist to r
197 as changed substantially in the last decade, it is unknown whether the burden of ESRD due to multiple
207 at high risk for adverse outcomes; however, it is unknown whether the magnitude of troponin elevatio
211 f motion occurs within a 3D environment, and it is unknown whether the principles from 2D motion proc
213 quently divergently transcribed in vivo, but it is unknown whether the resultant antisense RNAs are a
214 t cardiac function following bacteremia, but it is unknown whether the same occurs in humans with sev
217 ain insufficiently understood; specifically, it is unknown whether the unopposed activation of the im
223 creased risk of infective endocarditis (IE), it is unknown whether these abnormalities are associated
225 (memory phenotype CD8(+) T cells [TM]), but it is unknown whether these cells retain memory function
226 espread changes within the motor cortex, but it is unknown whether these changes are ultimately funne
235 sion of information processing in noise, but it is unknown whether these markers are present in pre-r
236 m clear skin without a precursor lesion, but it is unknown whether these melanomas can arise from mel
237 enes is associated with tobacco exposure but it is unknown whether these methylation changes translat
238 nt genetic changes in colorectal tumors, but it is unknown whether these mutations phenocopy gain-of-
245 herapeutic drugs and confer drug resistance, it is unknown whether these transporters are expressed o
246 and visual perceptual performance; however, it is unknown whether these two dopamine-mediated phenom
247 rons by chronic manipulations of firing, but it is unknown whether they are coinduced by the same act
249 enger receptors (SR-As) mediate dsRNA entry, it is unknown whether they contribute to signaling beyon
252 high levels of CD44 accumulate with age, but it is unknown whether this accumulation reflects their p
256 ated with a higher risk of suicide; however, it is unknown whether this association is also present i
257 of mortality of anaphylactic shock (AS), but it is unknown whether this association remains valid for
258 for the DAT endocytic brake is unknown, and it is unknown whether this braking mechanism is unique t
260 re depleted during ischemia-reperfusion, but it is unknown whether this depletion is a cause or an ef
261 y increases the risk of type 2 diabetes, but it is unknown whether this effect is specific to statins
262 ascular integrity at mid-gestation; however, it is unknown whether this enzyme contributes to later b
263 cognitive shifts could recruit the DMN, yet it is unknown whether this holds for nonhuman species.
265 to have low-grade systemic inflammation, but it is unknown whether this inflammation starts before sy
266 tion has been observed in human cancers, yet it is unknown whether this is a bystander event or a dri
268 with rhinovirus (RV) infections wheeze, but it is unknown whether this is due to more virulent strai
269 at AWR leads to improvement in function, but it is unknown whether this is specific to the abdominal
273 ) can be linked by apparent competition, but it is unknown whether this process is strong enough to b
277 ted with reduced dorsal striatal volume, but it is unknown whether this relationship extends to adole
280 ng necessary proteins at synaptic sites, but it is unknown whether this requires initiation or bypass
283 ed risk of cardiovascular disease (CVD), but it is unknown whether this risk remains after adjustment
284 0-year risk of CVD in midadulthood; however, it is unknown whether this risk score is associated with
285 ed alga,Symbiodinium thermophilum Currently, it is unknown whether this symbiont originated elsewhere
287 CU) beds in the United States is increasing, it is unknown whether this trend is consistent across al
289 ociated with xeric/mesic ecotype divergence, it is unknown whether those traits evolve independently
291 ecreased risk of rejecting a maternal graft, it is unknown whether TME plays a role in development of
292 ARE proteins between opposing membranes, but it is unknown whether transmembrane domains (TMDs) of SN
298 al S-adenosyl-l-methionine (SAM) enzyme, but it is unknown whether viperin actually exploits radical
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