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6 haled PGE(2) levels are not reduced, so that it is unlikely that a deficiency of PGE(2) is an importa
8 nate exchange reaction is preferred and that it is unlikely that a four-coordinate Cu(I) species play
10 ery or gynecological surgery INTERPRETATION: It is unlikely that a high proportion of UK sCJD cases a
11 y either type of nonplanar core deformation; it is unlikely that a protein engendered core deformatio
12 climate system and the global carbon cycle, it is unlikely that a reduction in warming would be imme
14 s of infection by PERV are better understood it is unlikely that a significant number of porcine xeno
16 ard effect' has often been dismissed because it is unlikely that a single gene can code for altruism
17 re thought to play dominant oncogenic roles, it is unlikely that a single genetic alteration by itsel
19 have a variable distribution in Salmonella, it is unlikely that a single locus will be found to be r
21 of economic evaluations have been proposed, it is unlikely that a standard/common methodology will (
22 rence: (1) anti-CCP is a cause of RF and (2) it is unlikely that a third confounding factor contribut
26 he differential effects of Li and SB-415286, it is unlikely that acute inhibition of GSK3 contributes
30 reveal that TNF-R signaling is complex, and it is unlikely that all cells and both receptors will re
33 given the complex etiology of the disorder, it is unlikely that all susceptibility regions have been
35 ibly involving arachidonic acid metabolites, it is unlikely that AngII contributes to the decreased N
38 new drugs are being developed and evaluated, it is unlikely that any of these new medications will re
42 view of such disease and tissue complexity, it is unlikely that any single process is solely respons
44 iming and the effect on synaptic plasticity, it is unlikely that APP-ICD-dependent transcription is a
46 consideration of the evidence suggests that it is unlikely that association of Kv4 channels with the
53 possibility of hydrogen tunneling; however, it is unlikely that carbon can engage in significant tun
54 owing to large internal climate variability, it is unlikely that changes in the rate of anthropogenic
55 sential for beta-globin gene expression, and it is unlikely that chromatin structure is affected eith
56 ates from short-lived virus-producing cells, it is unlikely that chronic infection is generally susta
61 terogeneous, complex metabolic disorder, and it is unlikely that control of hyperglycemia alone will
68 disability, available research suggests that it is unlikely that disturbances in psychiatric function
69 bservational data prohibit causal inference, it is unlikely that diuretics afford any material benefi
70 normalities are common to all somatic cells, it is unlikely that dysfunction of this particular pathw
71 of distinct object and action categories, so it is unlikely that each category is represented in a di
72 in primary HIV-1 infection and indicate that it is unlikely that early treatment during primary infec
74 ican HCC may contain EBV-infected cells, but it is unlikely that EBV plays a major role in the carcin
76 tion of ERD1 and ClpP, but they suggest that it is unlikely that either plays a major role during sen
77 kkee et al. provide additional evidence that it is unlikely that either psoriasis or severe psoriasis
78 ve to that of wild type CheY, indicated that it is unlikely that either Thr87 or Lys109 plays a direc
82 ence over a short period of human evolution, it is unlikely that FA arises through germline genetic c
83 ffect has been causally linked to lactation, it is unlikely that fathers would show a similar change.
86 good fit of the model to this large dataset, it is unlikely that further information on presence of g
87 as any specific effect on carcinogenesis and it is unlikely that further study will reveal something
88 intain a fairly large number of chromosomes, it is unlikely that GC-rich isochores are vanishing in t
91 neurons once PTTH production is detectable, it is unlikely that Gt directly regulates PTTH expressio
93 without any apparent abnormalities, so that it is unlikely that hemizygosity of CDC45 alone is respo
94 cteristics depend strongly on pore geometry, it is unlikely that hexameric and tetrameric pores would
97 ction still remains quite inefficient; thus, it is unlikely that hPolkappa would bypass an abasic sit
101 ffect the levels of any DNA adduct measured, it is unlikely that interindividual variation in NAT2 fu
103 d because of standardization techniques, and it is unlikely that it is a result of a change in tree g
104 oxybenzaldehyde) stimulated the Na+ pumping, it is unlikely that it is a secondary effect due to the
105 e from randomised trials also indicates that it is unlikely that large absolute excesses in other ser
108 these observations which require validation, it is unlikely that levels of measured homozygosity caus
109 ia adapt to their ecological niches and that it is unlikely that Lrp-related proteins in other organi
112 therian mammals, this approach suggests that it is unlikely that many modern orders arose much earlie
116 e and structure of this protein is such that it is unlikely that minK alone forms functional channels
118 ere comprised of varying muscle fiber types, it is unlikely that muscle location or fiber type determ
125 ndbrain express the NMDAR1 receptor subunit, it is unlikely that noradrenergic inter-neuronal pathway
126 hey are not required for HFV replication and it is unlikely that nuclear localization of Gag protein
129 hat functionally related proteins cooperate, it is unlikely that only fascin bundles actin in these p
130 e range of their physicochemical properties, it is unlikely that OPEs are mainly in the particle phas
133 tor or were the result of reverse causation, it is unlikely that parental smoking would predict Parki
135 small number of transplantations means that it is unlikely that pivotal randomized, controlled trial
136 cytoplasmic tail lacks a PKA consensus site, it is unlikely that PKA acts directly on beta3 integrin.
141 ut the synaptic operating range, which means it is unlikely that presynaptic membrane potential contr
142 While such ontological questions remain, it is unlikely that progress can be made on the molecula
144 c conditions but were specific IgE-negative, it is unlikely that questionnaires will ever capture the
145 tical RDS sampling assumptions hold exactly, it is unlikely that RDS performs any better in practice
148 Although based on its biochemical properties it is unlikely that Rep40 plays a central role as a repl
149 ion in a homozygously deleted 17p13.3 locus, it is unlikely that RPH3AL is a gene involved in the onc
152 milar between widespread, allopatric clades, it is unlikely that selective pressures would be so simi
159 tients who began using statins indicate that it is unlikely that statins confer a clinically importan
160 ate in cholesterol biosynthesis, we conclude it is unlikely that sterol biosynthesis continues past l
161 t discover donor HBV, HCV, or HIV infection, it is unlikely that subclinical disease transmission wil
162 f treatment-arm-specific therapy and only if it is unlikely that subsequent treatment and/or follow-u
163 costs and the required length of follow-up, it is unlikely that such a trial will ever be conducted.
166 no significant inhibition on cytoadherence, it is unlikely that sulfated glycoconjugates are used di
167 a (approximately 105 million years ago), and it is unlikely that "sweepstakes" dispersal accounts for
168 on is unaffected by the hsl5/cdc28 mutation, it is unlikely that synthetic lethality results from red
172 kely be small, and perhaps more importantly, it is unlikely that the bias will introduce false-positi
176 , suggesting that, in contrast to tamoxifen, it is unlikely that the clinical use of arzoxifene will
179 ction, and structural analysis suggests that it is unlikely that the cytoplasmic filaments and the fl
182 ell swelling-induced increases in TC uptake, it is unlikely that the effect of cell swelling on TC up
184 regions of the rice and Arabidopsis genomes, it is unlikely that the extent of colinearity will be su
188 f 1.2 x 10(-4) from an F-test indicates that it is unlikely that the ground-state anomeric effect and
189 er in ICUs outside the development database, it is unlikely that the incremental cost-effectiveness g
191 ited RPS12 RNAs contain long poly(A) tracts, it is unlikely that the long poly(A) tract is the sole s
199 be straightforward to analyse the data, but it is unlikely that the resulting model would reflect th
203 individual influenza virus proteins, and so it is unlikely that the stimulating antigen is of viral
204 gh cluster around the native structure, then it is unlikely that the subunits form a stable biologica
207 e in the treatment of patients with LD-SCLC, it is unlikely that the three-drug combination with thor
211 not expressed in a cascade fashion and that it is unlikely that their major role is to recognize the
212 logy of sepsis are simultaneously activated, it is unlikely that therapy directed at any one of them,
214 ream of the start of translation; therefore, it is unlikely that there are any pre- or pro-regions as
216 hanisms underpinning these associations, and it is unlikely that there is a "one system fits all" mec
217 , in a full-length ABC transporter like Pgp, it is unlikely that there is complete association and di
218 ly occur at a low multiplicity of infection, it is unlikely that these deletions are propagated in na
221 his protein in addition to GR stabilization, it is unlikely that these functions include metabolism o
223 rase inhibitors, we previously proposed that it is unlikely that these numerous UL29 foci actually re
224 gainst medical advice were excluded, because it is unlikely that these patients had sustained an AMI.
226 s can result in egg activation in the mouse, it is unlikely that these proteins are used by the sperm
228 f vertebrate embryos are not clear, although it is unlikely that these roles are evolutionarily relat
230 ough health outcomes were not measured here, it is unlikely that these small changes in nutrient meas
231 ferred by high metallation of G37R and G93A, it is unlikely that these soluble SOD1s are prone to agg
232 and corresponding low equilibrium constants, it is unlikely that these species could have accumulated
234 oanionic (20%) forms at physiological pH and it is unlikely that these two forms have the same cleara
236 tracellular calcium increase induced by CCK, it is unlikely that they acted at receptors or transmemb
238 ty of inflammation; however, except for AGP, it is unlikely that they can correct for malaria-induced
240 viruses tend to infect related host species, it is unlikely that they often infect the same host spec
241 res detect a large number of organism types, it is unlikely that they will disappear from clinical pr
244 ze the chitin portion of the Nod signal, and it is unlikely that this binding activity represents a s
246 ole for RNA cannot be completely discounted, it is unlikely that this demethyl-ation reaction involve
247 y of CARD15 mutations than the SOJ controls, it is unlikely that this difference fully explains the e
248 cantly different between the two groups, and it is unlikely that this difference was due to the manne
249 P or nonhydrolyzable triphosphate alone, and it is unlikely that this effect is due to the presence o
251 nsufficiency is the mechanism underlying DOA it is unlikely that this figure will be mutation-specifi
253 e cap-independent synthesis, indicating that it is unlikely that this is the primary mechanism for th
257 as one option for increasing the donor pool, it is unlikely that this will in itself be able to bridg
258 immunized with the nonprotective immunogen, it is unlikely that TNF-alpha activates the neutrophils,
259 s generated by display technologies, because it is unlikely that traditional approaches will provide
263 bundance of tau ending at D421 indicate that it is unlikely that truncation at this site is necessary
265 ks GABA reuptake, does not prolong IPSCs, so it is unlikely that uptake inhibition accounts for the e
268 coming from the genome sequencing projects, it is unlikely that we will ever have an atomic resoluti
269 Since these structures are two dimensional, it is unlikely that X-ray crystallographic methods will
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