ライフサイエンスコーパス: it remains unknown whether

1 Despite these findings, it remains unknown whether 5-HT2B receptors directly mod

2 However, it remains unknown whether a causal relationship exists

3 However, it remains unknown whether a given sensory memory trace

4 However, it remains unknown whether a loss of Cav-3 affects the p

5 (MTA1s) are elevated in human breast cancer, it remains unknown whether a regulatory cross-talk exist

6 In particular, it remains unknown whether abnormal connectivity pattern

7 However, it remains unknown whether activation of p38 is sufficie

8 nction produce profound changes in movement, it remains unknown whether activity-dependent plasticity

9 However, it remains unknown whether additional epigenetic feature

10 increased mortality rate in septic patients, it remains unknown whether administration of IalphaI/Pal

11 In addition, it remains unknown whether age-related LV stiffening is

12 However, it remains unknown whether AgRP neuron stimulation is su

13 vered in most major vertebrate lineages, but it remains unknown whether all SFMs share excitation-con

14 However, it remains unknown whether alveolar macrophages have a u

15 AMBP-1 augments AM-mediated action in vitro, it remains unknown whether AM/AMBP-1 maintains vascular

16 It remains unknown whether an open chromatin is necessar

17 d by saccades can enhance visual perception, it remains unknown whether and how presaccadic modulatio

18 However, it remains unknown whether and how stem cell centrosomes

19 However, it remains unknown whether and how the 2 signaling pathw

20 However, it remains unknown whether and how the GTR plays a causa

21 It remains unknown whether and how UPR components can be

22 However, it remains unknown whether and when elevation of cytokin

23 Thus far, it remains unknown whether and where either of these two

24 s of seeking information about a reward, but it remains unknown whether, and how, neurons encode choi

25 important immune system infection cues, but it remains unknown whether animals possess sensory mecha

26 Moreover, it remains unknown whether arbitrating between explorati

27 calls in response to echo feedback; however, it remains unknown whether audiovocal feedback contribut

28 intracellular reactive oxygen species (ROS), it remains unknown whether autophagy is essential in the

29 However, it remains unknown whether autophagy plays a critical ro

30 However, it remains unknown whether BIK1 functions in plant defen

31 However, it remains unknown whether BMAL1 ubiquitination affects

32 However, it remains unknown whether BMP signaling can promote sel

33 It remains unknown whether BMPs have a specific role dur

34 in display altered pain-modulation efficacy, it remains unknown whether brainstem pain-modulation cir

35 Furthermore, it remains unknown whether Casq2 regulates SR Ca2+ relea

36 However, it remains unknown whether Cav-3 expression is required

37 However, it remains unknown whether caveolin-1 functions as a tum

38 However, it remains unknown whether caveolin-1 is involved in cel

39 However, it remains unknown whether caveolin-1 plays any role in

40 However, it remains unknown whether caveolins are expressed withi

41 However, it remains unknown whether CEA, in turn, influences TGF-

42 However, it remains unknown whether certain types of sex partners

43 It remains unknown whether changes in gap junctional con

44 ributes to adaptive physiological responses, it remains unknown whether changes in SK channel functio

45 It remains unknown whether changes in the replication en

46 es and humans ([6-8] and Supplemental Data), it remains unknown whether chimpanzees also show face-se

47 However, it remains unknown whether chronic drug use compromises

48 pheral nervous system is well characterized, it remains unknown whether CLA also affects vascular mor

49 Remarkably, it remains unknown whether clathrin is strictly necessar

50 However, it remains unknown whether clinical-scale hESC-CM transp

51 However, it remains unknown whether cofactors materially particip

52 sons between VH-IVUS and OCT are lacking and it remains unknown whether combining these modalities im

53 However, it remains unknown whether continued Wnt signaling in DP

54 However, it remains unknown whether CREB function is required for

55 However, it remains unknown whether critical dynamics is affected

56 It remains unknown whether cross-priming ability transla

57 However, it remains unknown whether d-serine participates in the

58 It remains unknown whether declines in stem cell functio

59 lian species form dominance hierarchies, but it remains unknown whether differences in social status

60 It remains unknown whether different forms of homeostati

61 sed by horizontal cells in the avian retina, it remains unknown whether different types of horizontal

62 d in B cells in a stimulus-dependent manner, it remains unknown whether differential activation of th

63 Furthermore, it remains unknown whether direct interactions that have

64 It remains unknown whether distinct immune responses dur

65 However, it remains unknown whether dividing attention degrades t

66 However, its remains unknown whether down-regulation of caveolin-

67 However, it remains unknown whether downregulation of caveolin-1

68 It remains unknown whether drug development is accelerat

69 been suggested for FSHD pathophysiology and it remains unknown whether DUX4 expression can account f

70 nt of many other kinds of cell interactions, it remains unknown whether E-cadherin directly transduce

71 s for starting antiretroviral treatment, but it remains unknown whether either of them is more advant

72 However, it remains unknown whether electrical brain stimulation

73 rtebrates has been highly controversial, and it remains unknown whether endogenous mesoderm inducers

74 However, it remains unknown whether Eos influence the biology of

75 While it remains unknown whether ERbeta is a substrate of Mnk2

76 ntal cortex in clinical depression; however, it remains unknown whether excitation or inhibition of p

77 egulator of the selection of new neurons but it remains unknown whether experience provides specific

78 In particular, it remains unknown whether expression of CD103/beta(7) b

79 ugh male sex steroids are immunosuppressive, it remains unknown whether female sex hormones are immun

80 However, it remains unknown whether flotillins interact with cave

81 However, it remains unknown whether foraging for social resources

82 te sampling on the initial biopsy, such that it remains unknown whether G3 tumors generally progress

83 However, it remains unknown whether GA toxicity is due to direct

84 It remains unknown whether Gbetagamma specificity in viv

85 However, it remains unknown whether gemfibrozil improves outcome

86 However, it remains unknown whether ghrelin has any effects on HM

87 However, it remains unknown whether glial cells are capable of de

88 ptake into yeast expressing AtSUC2; however, it remains unknown whether glucosides other than sucrose

89 ated in the pathology of fragile X syndrome, it remains unknown whether group I mGluR-mediated protei

90 However, it remains unknown whether gut microbiota control immuni

91 rating tonic and synaptic currents; however, it remains unknown whether H2O2 directly modulates GABAA

92 ns target Arp2/3 for intracellular mobility, it remains unknown whether HIV-1 actively modulates the

93 accelerated periodontal tissue destruction, it remains unknown whether hyperglycemia, a major metabo

94 Regardless of this, it remains unknown whether ibuprofen could act as an end

95 However, it remains unknown whether increased caveolin-3 levels i

96 However, it remains unknown whether increasing adult neurogenesis

97 It remains unknown whether inflammation impacts other br

98 However, it remains unknown whether injection of IalphaIp at late

99 However, it remains unknown whether integrins outside FAs can tra

100 It remains unknown whether intervention for proteinuria

101 However, it remains unknown whether INZ may globally affect p53-d

102 duction and protects myocardium against I/R, it remains unknown whether ischemic preconditioning, whi

103 a role in saccade target selection; however, it remains unknown whether it exerts effects on visual p

104 litates CFTR endocytosis in some cell types, it remains unknown whether it is critical for CFTR uptak

105 The amygdala is important in emotion, but it remains unknown whether it is specialized for certain

106 ssociation with substantial health benefits, it remains unknown whether its favorable effects are med

107 ents with primary antibody deficiency (PAD), it remains unknown whether its pathogenesis is similar w

108 ed immune responses after trauma-hemorrhage, it remains unknown whether L-arginine protects against l

109 It remains unknown whether L1 expression simply highligh

110 In particular, it remains unknown whether learning can reshape neural r

111 ection against many infectious diseases, but it remains unknown whether lethal immunopathological cha

112 However, it remains unknown whether, like sense transcription of

113 It remains unknown whether liver fibrosis stage influenc

114 However, it remains unknown whether loss of Cav-1 is sufficient t

115 However, it remains unknown whether loss of Cav-1 occurs in the b

116 s abundant in mammary fat pads (stroma), but it remains unknown whether loss of Cav-1 within mammary

117 However, it remains unknown whether loss of caveolin-1 significan

118 However, it remains unknown whether lysosomal sorting mechanisms

119 However, it remains unknown whether mammalian FIP200 regulates au

120 s to silence viral infection in human cells, it remains unknown whether mammalian viruses naturally e

121 axons part-way through the optic nerve, but it remains unknown whether mature axons can reenter the

122 sensitive to extracellular metabolites, but it remains unknown whether metabolites present at an inf

123 s a known confounder of association studies, it remains unknown whether methods developed to control

124 t) affects multiple functions of astrocytes, it remains unknown whether mHtt impairs the production o

125 However, it remains unknown whether mindfulness meditation engage

126 ne in the recruitment of inflammatory cells, it remains unknown whether MIP-1alpha plays any role in

127 However, it remains unknown whether molecular alterations at non-

128 However, it remains unknown whether moral reasoning level is asso

129 ning (NHEJ) has been extensively studied but it remains unknown whether more complex DSBs require a d

130 However, it remains unknown whether MSCs have immunoregulation on

131 tein and regulates p53-dependent DNA repair, it remains unknown whether MTA1 also participates in p53

132 d (n-3 PUFA) on cell signaling transduction, it remains unknown whether n-3 PUFA treatment modulates

133 due to subtle neurochemical differences, and it remains unknown whether naturally occurring variation

134 However, it remains unknown whether neoplasia associated with Pte

135 However, it remains unknown whether nestin(+) cells regulate infl

136 correlates with dementia and neuronal loss, it remains unknown whether neurofibrillary pathology cau

137 However, it remains unknown whether NK cells can directly mediate

138 nal L1 loci are present in the same genomes, it remains unknown whether non-functional L1s have any t

139 of modification-specific effector proteins, it remains unknown whether nonhistone chromatin proteins

140 However, it remains unknown whether NSAIDs and zinc chelation may

141 they have been extensively studied in vitro, it remains unknown whether nucleic acid triplexes play n

142 It remains unknown whether or how these therapies suppor

143 les has been suggested for these events, but it remains unknown whether or how this self-interaction

144 However, it remains unknown whether or not Setd1a controls specif

145 However, it remains unknown whether or not this putative tetramer

146 It remains unknown whether other types of stress signals

147 However, it remains unknown whether overexpression of caveolin-1

148 However, it remains unknown whether Pax genes interact with Eya1

149 However, it remains unknown whether pepcans occur in the peripher

150 In particular, it remains unknown whether Pet54p is a primary RNA-bindi

151 sitol-3,4,5-trisphosphate in cell migration, it remains unknown whether PI(3,4)P2 plays a distinct ro

152 However, it remains unknown whether PKG-I deficiency induces pulm

153 mponents of the gamma-secretase complex, but it remains unknown whether presenilin regulates synaptic

154 However, it remains unknown whether presynaptic NMDARs exist in t

155 It remains unknown whether primary prevention strategies

156 It remains unknown whether pro-catecholamine pharmacolog

157 It remains unknown whether prodromal symptoms are predic

158 glucocorticoids, cyclosporine, and morphine, it remains unknown whether prolactin has any salutary ef

159 a late hypodynamic phase (20 hrs after CLP), it remains unknown whether prostacyclin or prostaglandin

160 However, it remains unknown whether reactive oxygen species are i

161 It remains unknown whether referral patterns for high-ri

162 At present, it remains unknown whether RGS proteins play a role in r

163 ns are attenuated by advanced recipient age, it remains unknown whether risks associated with lower-q

164 However, it remains unknown whether secreted microRNA-targeted pr

165 It remains unknown whether serum IgMs interplay with fic

166 However, it remains unknown whether SHP-1 interacts with nephrin

167 It remains unknown whether Sim1 neurons regulate energy

168 However, it remains unknown whether simple functional tradeoffs u

169 However, it remains unknown whether slow, affective touch, can al

170 In particular, it remains unknown whether soluble Abeta oligomers can f

171 ts ecosystem functioning and resilience, yet it remains unknown whether species' contributions to fun

172 It remains unknown whether specific alterations in nucle

173 -T cells correlates with clinical responses, it remains unknown whether specific cell subsets within

174 However, it remains unknown whether specific eating habits regard

175 ares many features with mammalian sleep, but it remains unknown whether spontaneous and evoked activi

176 However, it remains unknown whether starch-deficient mutants affe

177 It remains unknown whether such an interconnected networ

178 It remains unknown whether such mind wandering is unsyst

179 pulations; however, for bacteria in the wild it remains unknown whether such population-level organiz

180 chanisms control PD-L1 expression in cancer, it remains unknown whether such regulatory loops operate

181 It remains unknown whether such shifts in biodiversity a

182 their discovery more than 40 years ago, but it remains unknown whether such structures occur natural

183 rove the quality of pediatric resuscitation, it remains unknown whether survival in children with in-

184 However, it remains unknown whether survival of patients with hep

185 Moreover, it remains unknown whether SUV3 plays a direct role in m

186 However, it remains unknown whether synaptic plasticity in mPFC-B

187 However, it remains unknown whether T cell vaccination elicits an

188 However, it remains unknown whether the activation of NK cells in

189 However, it remains unknown whether the ADAMTS13-VWF axis plays a

190 sized to underlie some of these effects, but it remains unknown whether the binding of biochemical si

191 It remains unknown whether the biomechanical forces impo

192 It remains unknown whether the cortical implementation o

193 ention have been documented in older adults, it remains unknown whether the critical ability to orien

194 It remains unknown whether the expression of cell-mediat

195 mic substrate conducive to sudden death, but it remains unknown whether the extent of hypertrophy is

196 commonly associated with germ cell defects, it remains unknown whether the FA pathway is involved in

197 However, it remains unknown whether the frequent consumption of f

198 It remains unknown whether the function of human HSCs is

199 It remains unknown whether the genotype of the myocyte i

200 However, it remains unknown whether the global defect in NF-kappa

201 umen and induces local immune responses, but it remains unknown whether the gut microbiota can induce

202 It remains unknown whether the impressive effects of CD1

203 However, it remains unknown whether the lagging chromosomes obser

204 Thus, it remains unknown whether the large TRPML1(V432P)-media

205 omes in patients at high risk for ASCVD, but it remains unknown whether the level of kidney function

206 However, it remains unknown whether the m(6)A modification contro

207 Thus, it remains unknown whether the magnitude of the LPS-elic

208 ac, endocardial and haematopoietic lineages, it remains unknown whether the mammalian heart tube serv

209 However, it remains unknown whether the mammalian RNAi pathway ha

210 nown to be patterned by neural activity, but it remains unknown whether the map topography of such hi

211 Therefore, it remains unknown whether the mechanism of the unconven

212 the development of several cancers; however, it remains unknown whether the miR-17-92 cluster is able

213 It remains unknown whether the NF-kappaB shuttling betwe

214 However, it remains unknown whether the OFC is selectively involv

215 However, it remains unknown whether the often-seen coupling of hy

216 ficient for passive behavioral conditioning, it remains unknown whether the phasic dopaminergic signa

217 ammalian olfactory bulb throughout life, but it remains unknown whether the properties of new neurons

218 However, it remains unknown whether the protein undergoes any cha

219 ever, as only two populations were analyzed, it remains unknown whether the signature of selection ex

220 However, it remains unknown whether the size, microenvironment or

221 However, it remains unknown whether the underlying white matter a

222 However, it remains unknown whether the use of different somatic

223 Furthermore, it remains unknown whether there are differences in atro

224 It remains unknown whether there are functional differen

225 However, it remains unknown whether there are progressive decreas

226 function in inhibitory synapse development, it remains unknown whether there is a unifying mechanism

227 However, it remains unknown whether there is any regulatory inter

228 It remains unknown whether these abnormalities are mecha

229 However, it remains unknown whether these are paralleled by diffe

230 story of autoimmune and atopic diseases, but it remains unknown whether these associations apply to a

231 at obesity results in lymphatic dysfunction, it remains unknown whether these changes are permanent o

232 However, it remains unknown whether these effects are direct or i

233 elevated in adult cancer survivors; however, it remains unknown whether these elevations are related

234 ng gene expression data from cell lines, and it remains unknown whether these eQTLs also have a regul

235 rge quantities of expanded NK cells ex vivo, it remains unknown whether these expanded NK cells can p

236 However, it remains unknown whether these findings are relevant t

237 It remains unknown whether these health improvements wil

238 e known to be activated during inflammation, it remains unknown whether these molecules regulate infl

239 However, it remains unknown whether these neuronal scaling laws a

240 Although it remains unknown whether these phenotypes are connecte

241 the development of thymus-seeding cells, but it remains unknown whether these proteins play a role in

242 However, it remains unknown whether these responses are driven pr

243 elopment of vaccines targeting this protein, it remains unknown whether these responses could engage

244 (sncRNAs) into oocytes during fertilization, it remains unknown whether these sperm-borne sncRNAs tru

245 However, it remains unknown whether these target genes are direct

246 However, it remains unknown whether these two pathways cooperate

247 neurons play critical roles in seizures, but it remains unknown whether these vary across interneuron

248 sensory, perceptual and cognitive processes, it remains unknown whether they are phase-locked signals

249 the major histocompatibility complex (MHC), it remains unknown whether they can use olfactory cues t

250 events after an acute coronary syndrome, yet it remains unknown whether they derive enhanced benefit

251 However, it remains unknown whether they display phenotypic varia

252 s via programmed death-ligand 1 (PD-L1), but it remains unknown whether they exert any effects on B c

253 ursts), is observed in reduced preparations, it remains unknown whether they occur or what their role

254 However, it remains unknown whether this adaptation is fixed, or

255 wing various adverse circulatory conditions, it remains unknown whether this agent attenuates the dep

256 own to possess anti-inflammatory properties, it remains unknown whether this agent has any beneficial

257 However, it remains unknown whether this alteration in energy bal

258 It remains unknown whether this assumption is correct du

259 It remains unknown whether this capacity is present earl

260 It remains unknown whether this compensation also occurs

261 It remains unknown whether this conservation value can b

262 It remains unknown whether this electrical activity is r

263 ses and rapidly fixes in the population).Yet it remains unknown whether this form of natural selectio

264 However, it remains unknown whether this heterogeneity may accoun

265 se of respiratory infections in infants, but it remains unknown whether this infection is transmitted

266 However, it remains unknown whether this is a common and potentia

267 However, it remains unknown whether this is specific to PD or whe

268 However, it remains unknown whether this pathway operates in vivo

269 However, it remains unknown whether this principle applies to the

270 However, it remains unknown whether this property is common to Ne

271 However, it remains unknown whether this protein has any effect o

272 It remains unknown whether this racial discrepancy refle

273 bsence of direct measures of human dopamine, it remains unknown whether this reflects a quantitative

274 y GlyR tone is widely observed in the brain, it remains unknown whether this specifically reflects gl

275 However, it remains unknown whether this strategy would improve s

276 It remains unknown whether this vaccine will prevent car

277 It remains unknown whether Tmods have other functional r

278 eta are both often elevated in septic shock, it remains unknown whether TNF-alpha or IL-1beta are the

279 r decades of studies and regulation efforts, it remains unknown whether to what degree and at what co

280 nctions (EF) in children can be trained, but it remains unknown whether training-related benefits eli

281 However, it remains unknown whether tyrosine-phosphorylated beta-

282 It remains unknown whether unrelated infections will com

283 Moreover, it remains unknown whether vaccination can augment such

284 It remains unknown whether visual experience is required