ライフサイエンスコーパス: itchy

1 Itchy, a mouse homologue of human AIP4, is a Nedd4 famil

2 r activities to avoid the annoyingly intense itchy allergic reactions, leading to significant worseni

3 We compared the ability of ITCHY and DNA shuffling to create interspecies fusion li

4 The lesions tend to be less itchy and poorly responsive to standard therapy, includi

5 was defined by parental report of a typical itchy and/or flexural rash.

6 uncation for the creation of hybrid enzymes (ITCHY) and SCRATCHY] and low-homology techniques (recomb

7 ndicate that Nedd4 family E3s, in particular Itchy, downmodulate LMP2A activity in B-cell signaling.

8 Itch or itchy E3 ubiquitin ligase was initially discovered by ge

9 In innate immunity, the itchy E3 ubiquitin protein ligase (ITCH)-A20 ubiquitin-e

10 Nine of them had infiltrated itchy erythematous and vesiculous plaques at the injecti

11 1.81; 95% CI: 1.41, 2.58); watery, burning, itchy eyes (OR = 1.61; 95% CI: 1.20, 2.16); and stuffy,

12 Moreover, itchy eyes had the higher symptom prevalence than watery

13 visited our hospital because of nasal drop, itchy eyes, and dyspnea after lunch every two months for

14 allergic reaction occurs but can include red itchy eyes, sneezing, nasal congestion, rhinorrhea, coug

15 parental atopy, FLG status, or report of an itchy flexural rash at 2 months.

16 on K1413 by the E3 ubiquitin-protein ligase Itchy homolog (Itch), a Nedd4 family member.

17 positives from each library illustrated that ITCHY identified a more diverse set of active fusion poi

18 As a model system, single-crossover ITCHY (incremental truncation for the creation of hybrid

19 uncation for the creation of hybrid enzymes (ITCHY) is a novel tool for the generation of combinatori

20 Homozygous itchy mice develop a fatal, late-onset autoimmune-like d

21 Itchy mice lack the E3 ligase, Itch, and show dysregulat

22 tions of immunoglobulin G1 (IgG1) and IgE in itchy mice were also increased.

23 e aberrant activation of immune responses in itchy mice.

24 ase that is disrupted in nonagouti-lethal or itchy mice.

25 at is disrupted in non-agouti lethal mice or Itchy mice.

26 This phenotype resembled that of Itchy mutant mice, suggesting that Ndfip1 might affect t

27 t least two symptoms: 'repeated sneezing and itchy nose', 'blocked nose for more than one whole hour'

28 1 rhinitis symptom (repeated sneezing and/or itchy nose, blocked nose for >1 h, or runny nose without

29 ocked nose, 48% rhinorrhea, and 46% sneezing/itchy nose.

30 braries generated by incremental truncation (ITCHY) of two distinct parental sequences are created, a

31 olor changes, and its deletion results in an itchy phenotype with constant skin scratching and multi-

32 Although itchy rash is a nonspecific manifestation, it may be con

33 ECTIVES To assess the prevalence of reported itchy rash lasting longer than 3 days among the general

34 Atopic dermatitis, defined as an itchy rash on typical locations from birth to 6 years.

35 ifetime age-standardized prevalence rates of itchy rash that lasted longer than 3 days.

36 The overall prevalences of itchy rash were 19.3% (95% CI, 18.6%-20.0%) during the m

37 s (allergy, hay fever, eczema, rhinitis, and itchy rash) and serum-specific immunoglobulin E (IgE) le

38 (OR = 1.61; 95% CI: 1.20, 2.16); and stuffy, itchy, runny nose (OR = 1.56; 95% CI: 1.16, 2.08).

39 of drowsiness, hair loss, nausea, and dry or itchy scalp were reported while patients were receiving

40 utoimmune disease phenotype characterized by itchy skin and multiorgan inflammation.

41 A hallmark of AD is dry itchy skin due, at least in part, to defects in skin gen

42 cond decade of life with self-described red, itchy skin within a large plaque of FDH on her left post

43 m, sparse and slow-growing hair, and dry and itchy skin.

44 The detection of pruritic (itchy) stimuli is mediated by a variety of receptors and

45 agia, altered gastrointestinal motility, and itchy swollen skin.

46 Furthermore, some of the hybrids found by ITCHY that were fused at nonhomologous locations had act

47 uncation for the creation of hybrid enzymes (ITCHY), that creates combinatorial fusion libraries betw

48 nother, as yet unidentified locus designated itchy (the provisional gene symbol is Itch), that is res

49 with the most recent sexual partner; and (c) itchy vaginal discharge in the previous 30 d, possibly i

50 Self-reported itchy vaginal discharge was associated with all categori

51 ced odds of condom use and increased odds of itchy vaginal discharge, which is potentially indicative

52 contact urticaria (CCU) is characterized by itchy wheal and flare responses due to the release of hi