ライフサイエンスコーパス: iteration

1 sed on the linear regression model (N=10,000 iterations).

2 selection and stronger self-play in the next iteration.

3 the lessons learned were tested in a second iteration.

4 eling and enzymatic multimodule skipping and iteration.

5 ned can serve as donors for another coupling iteration.

6 ibility trials after having undergone device iteration.

7 reduces the computational complexity of each iteration.

8 sequences from individuals on each bootstrap iteration.

9 omplex substrate image is subtracted at each iteration.

10 nterest (ROIs) in the heart as a function of iteration.

11 iple reflections by means of a least-squares iteration.

12 selection, procedural technique, and device iteration.

13 hinge point was varied and tested with each iteration.

14 ixel position of the fluorophore in a single iteration.

15 kely dynamic flux distribution in just a few iterations.

16 CNV, which in some cases were part of larger iterations.

17 er ICUs and internally by bootstrap on 1,000 iterations.

18 mated the true effectiveness in 88% of model iterations.

19 new data that will most benefit future model iterations.

20 fficients remained largely unchanged between iterations.

21 or the factor and class of interest over all iterations.

22 subsequent measurements or wavefront shaping iterations.

23 2 decades ago and have gone through several iterations.

24 ructed image in less than half the number of iterations.

25 igands after a prespecified number of design iterations.

26 tumor heterogeneity) with a larger number of iterations.

27 ootstrap resampling was performed with 1,000 iterations.

28 uency features that are recovered with fewer iterations.

29 bsets and with 1, 2, 3, 4, 5, 10, 20, and 40 iterations.

30 between 1 versus 2 iterations and 2 versus 3 iterations.

31 han 5), with just 50%-60% increasing after 5 iterations.

32 gorithm converges rapidly, taking only a few iterations.

33 ilarity was obtained after only 12 PSI-BLAST iterations.

34 not involve any matrix decompositions in the iterations.

35 ng members, with refinement through multiple iterations.

36 sonably fast, typically around a few hundred iterations.

37 to detect subtle relationships in subsequent iterations.

38 tion using ML-EM algorithm for 25, 50 and 75 iterations.

39 quency of the motifs generated in subsequent iterations.

40 treatment was the optimal strategy in 34% of iterations.

41 ed that cost saving is achieved 37% of 1,000 iterations.

42 g patients, validated using 100 bootstrapped iterations.

43 sification accuracy was reported through the iterations.

44 already at a lower number of iterations (>1 iteration, 21 subsets).

45 ble only at a high number of iterations (>10 iterations, 21 subsets).

46 ete protein sequences, 5-9% of alignments at iteration 5 are non-homologous.

47 ) errors, and the largest fraction of FPs at iteration 5.

48 report a method for designing, with minimal iteration, a quantitative immunoassay that can be interp

49 se with a relaxed control of catalytic cycle iterations, a mechanistic property that explains the ori

50 From the fifth iteration and beyond, GAT enzymes conferred increasing g

51 Much of this progress has been due to the iteration and improvement of angioplasty technologies.

52 n steps within each Markov chain Monte Carlo iteration and Monte Carlo integration technique.

53 These results, which likely reflect device iteration and procedural evolution, support the use of t

54 Using a mixture of scientific intuition, iteration and serendipity, combinatorial materials scien

55 rom the ANM are used for deformation at each iteration and the conformational energy of the deformed

56 means of estimating these parameters without iteration and without assuming random mating.

57 t significant differences between 1 versus 2 iterations and 2 versus 3 iterations.

58 ered-subsets expectation maximization with 4 iterations and 32 subsets.

59 ordered-subsets expectation maximization (2 iterations and 8 subsets; 2D 6-mm gaussian, 3D 5- and 6-

60 h requires only a small number of O(MN) time iterations and increases power by modeling more realisti

61 Newer device iterations and longer term follow-up will be necessary a

62 Various iterations and modifications of traditional cyclophospha

63 pression thresholds, often requiring several iterations and refinements to capture the expression dyn

64 treatment was the optimal strategy in 37% of iterations and the combination of naloxone distribution

65 propose that it is mainly the high number of iterations and the immediacy of reciprocation opportunit

66 n and phasing are integrated within the same iteration, and a dynamic support is used.

67 eview, expert opinion, rounds of testing and iteration, and feedback from users.

68 of this function were investigated by direct iteration, and the model was validated by immunologic an

69 nning filter) and by OSEM with 28 subsets, 8 iterations, and a gaussian 5-, 10-, or 15-mm postreconst

70 nterrogations, repeated sensing/regeneration iterations, and employment in complex sample matrices su

71 er, maxSUV increased systematically at early iterations, and this trend continued as the number of it

72 led protocol for conducting several complete iterations around our FTE 'road map.' The in vitro porti

73 We employ two-level iteration as the solution strategy, which exhibits aspec

74 al with desired elastic properties in as few iterations as possible.

75 tions at a $50,000/QALY threshold and 65% of iterations at a $100,000/QALY threshold.

76 r-based therapy was cost-effective in 70% of iterations at a $50,000/QALY threshold and 65% of iterat

77 , warfarin was optimal in an equal number of iterations at a cost-effectiveness threshold of $100 000

78 The iteration based search appears rather rigorous, not only

79 efficient two-cycle [4+4+4] tetrasaccharide-iteration-based approach for rapid chemical synthesis of

80 el divide-and-conquer approach, so that each iteration begins with a tree produced in the prior itera

81 Iteration between computation, prediction, and observati

82 Iteration between design and experiment increased the de

83 ns can be computationally designed, and that iteration between design and structure determination pro

84 ncentration time series; and then, recursive iteration between the following two: (a) for a given pul

85 This statement updates the 2005 iteration, both of which were developed by the American

86 significantly deteriorates as the number of iterations builds up.

87 ralizing epitope will likely require several iterations comparing antigenicity and immunogenicity of

88 The template for a single iteration, complete with crosswind casting both before a

89 Each iteration consists of sequencing a novel portion of targ

90 Each iteration consists of two passes.

91 Starting from a terminal alkyne the iteration cycle consists of a C3 extension (allylation),

92 Three major iteration cycles were employed to improve upon potency,

93 ion begins with a tree produced in the prior iteration, decomposes the taxon set into overlapping sub

94 designed a muscarinic antagonist DART in one iteration, demonstrating applicability of the method to

95 The synthetic iterations described here not only led to improving pote

96 Analogues optimized through SAR iterations display low nanomolar enzymatic and cellular

97 validation of the testing dataset with 1000 iterations each to assess model detection accuracy.

98 model by using the copulas does not require iterations, elicitation of the priors, and complicated c

99 Our new MM algorithm converges in fewer iterations, eliminates marginal haplotypes from further

100 either the model converges or the number of iterations exceeds a maximum.

101 sitivity analyses and Monte Carlo simulation iterations, F-DNA remained reasonably cost-effective com

102 QALY compared with the status quo; >99.9% of iterations fell below the willingness-to-pay threshold o

103 hm by using a threshold of 2200 HU with four iterations for both steel and titanium prostheses.

104 reproducing the same area on all same-study iterations for SUV measurements.

105 Given the continued change in maxSUV with iterations, great care must be taken in selecting the nu

106 ere statistically different across different iteration groups.

107 ect was notable already at a lower number of iterations (>1 iteration, 21 subsets).

108 fect was measurable only at a high number of iterations (>10 iterations, 21 subsets).

109 h successive structure-activity relationship iterations identified analogs 2 (Dasatinib, BMS-354825)

110 h and how it has progressed into its current iteration, (ii) establish lessons learned from previous

111 The role of unmet needs identification, iteration in concept generation and development, and the

112 ethodology report (to be issued in its first iteration in May 2012) will begin to provide standards i

113 r QALY gained, FIT was preferred in 99.3% of iterations in Monte Carlo simulation.

114 ation of circulating immune cells induced by iterations in PBMC divalent cations and transduced by ox

115 RAF mutation testing was preferred in 59% of iterations in probabilistic sensitivity analysis at a th

116 ost-effective or dominant 96.7% and 87.5% of iterations in the 10-year model.

117 will enable rapid design and cost-effective iterations in the development stage, facilitating rapid

118 ake value (maxSUV) of changing the number of iterations in the reconstruction process on studies acqu

119 Health Questionnaire (PHQ 15) (plus enhanced iterations including an additional 10 items on specific

120 in class models, using a procedure of 20,000 iterations including the bootstrap for model optimizatio

121 kelihood expectation maximization equivalent iterations, including a point spread function model usin

122 ematic increase in the SUVs as the number of iterations increased.

123 s, and this trend continued as the number of iterations increased.

124 ocess is fundamentally iterative, where each iteration involves making model predictions, obtaining e

125 nce can only be accomplished through several iterations involving bioinformaticians, bench molecular

126 mption within the analogue synapses for each iteration is 1,000 x (20 x) lower compared to an impleme

127 Time complexity of each iteration is O(m (3) k) for an m x k SNP matrix where m

128 ty cutoff is then gradually reduced, and the iteration is repeated until no hits are returned from th

129 r programming (LP) problem and the number of iterations is independent of the number of organisms.

130 onsiderable number of design and fabrication iterations leading to long development times.

131 round of syntheses and biological evaluation iteration led to the highly active 5-cyclopropyl-2-(4-(2

132 ound to an ER construct, medicinal chemistry iterations led to (E)-3-(3,5-difluoro-4-((1R,3R)-2-(2-fl

133 These iterations led to the synthesis of 29b, a potent (IC(50)

134 The avgSUV increased at early iterations (less than 5), with just 50%-60% increasing a

135 In each iteration loop, the SNP that captures the most neighbori

136 ve accuracy in the smallest tumor, more OSEM iterations may be needed.

137 Iteration number and FWHM of the gaussian filter have a

138 ize has a larger impact on the features than iteration number and FWHM.

139 ty parameters had different sensitivities to iteration number.

140 d zone percentage were the most sensitive to iteration number.

141 nally, we reformulate the lower bound to the iterations' number of the switching-algorithm to make it

142 ty concentration and image noise for various iteration numbers and postsmoothing settings was evaluat

143 ted for a range of radial phantom positions, iteration numbers, and postreconstruction smoothing sett

144 ludes a terminal hairpin and a telomere-like iteration of a 5 bp sequence at the other terminus.

145 The algorithm is built on a heuristic iteration of a modified Needleman-Wunsch dynamic program

146 hits from the second iteration to the final iteration of a PSI-BLAST search, calculates the figure o

147 ic rate should be incorporated into the next iteration of AJCC staging.

148 spikelets, which differentiate in the final iteration of axillary meristem branching.

149 a-carbon atoms has been accomplished through iteration of completely regio- and stereoselective intra

150 A second iteration of congenic substrains was used to localize th

151 Iteration of electrocardiographic records, representing

152 ssessment with treatment choices, the latest iteration of guidelines from the Global Initiative for C

153 , we found that for many networks, the third iteration of label propagation receives a negative weigh

154 Thus a second method, an iteration of linear programs which scales easily to the

155 SuperTribes, constructed through a second iteration of MCL clustering, connect distant, but potent

156 Through iteration of modeling and stakeholder engagement, we dev

157 of enzyme function conservation in the third iteration of PSI-BLAST.

158 olation from selected cells and enable rapid iteration of screens and genetic reversion analyses to v

159 iously, we showed that a genetically encoded iteration of SDRE could target adenosines expressed in h

160 tivity model that refines itself after every iteration of synthesis and biological result.

161 A second iteration of synthesis and screening identified 29 which

162 ctorily integrated, and the most influential iteration of the cognitive model makes no mention of dop

163 The latest iteration of the Core Cardiology Training Statement (COC

164 For the first iteration of the course (2016), classrooms with a total

165 This iteration of the database reports chemical structures an

166 The next iteration of the DO web browser will integrate DO's exte

167 Upon the first publication of the fifth iteration of the Functional Annotation of Mammalian Geno

168 the language are consistent with the latest iteration of the language.

169 00 human proteins identified in the previous iteration of the NOPdb, we have now identified over 50 0

170 s were molecularly bred by DNA shuffling and iteration of the process, and the shuffled genes were cl

171 arthropod limbs is not regulated by a simple iteration of the proximal/distal patterning module emplo

172 le mutant (A2058U/A2062G) was isolated after iteration of the selection process.

173 an ensemble of network trajectories at each iteration of the simulated annealing algorithm.

174 um technologies could out-perform any future iteration of their classical counterparts, no matter how

175 Iteration of these efforts culminated in the discovery o

176 Iteration of this approach allows a stepwise expansion o

177 Since the publication of a previous iteration of this review 15 years ago, important advance

178 The models were evaluated through 1000 iterations of 5-fold cross-validations, 1000 bootstrappi

179 DMA), and nitrotyrosine levels, as well as 2 iterations of 60-second cuff-occlusion tests for assessm

180 tional coactivator motifs but contains three iterations of a domain found in the variant histone macr

181 copy, and combines information from multiple iterations of a fluorescence intensity/morphological seg

182 e repeats (SSRs) in DNA sequences are tandem iterations of a single nucleotide or a short oligonucleo

183 ant strains' genomes was coupled with serial iterations of a virus entry experiment, narrowing 28 can

184 Using serial iterations of an experiment involving virion entry and i

185 Subsequent iterations of analogue design and syntheses successfully

186 omains function selectively during different iterations of chain elongation to afford structural dive

187 l salt-sensitive (S) rat background, further iterations of congenic substrains were constructed and c

188 In addition, two iterations of consensus shuffling corrected a population

189 We show that two iterations of consensus shuffling improved a population

190 MOF was found to be reusable over successive iterations of CysNO additions without loss of activity.

191 Several iterations of design and characterization generated a 24

192 The paradigm consists of three iterations of design, synthesis, and X-ray crystallograp

193 motetrameric mutant, TG-15, was subjected to iterations of DNA shuffling and screened for enzyme vari

194 Eleven iterations of DNA shuffling improved enzyme efficiency b

195 p) held at the National Eye Institute, and 2 iterations of expert panel surveys were used in a modifi

196 Following multiple iterations of FACS, cells and progeny virions were shown

197 Iterations of fragment combination and structure-driven

198 After 9 iterations of history matching, a non-implausible region

199 Iterations of improved input data followed by fast re-co

200 The other was the role of future iterations of influenza NAATs and whether this testing w

201 all seed template was built upon using three iterations of library design, virtual screening, synthes

202 okaryotic genomes, and long SSRs composed of iterations of mono-, di-, tri-, and tetranucleotides are

203 Behaviours evolve by iterations of natural selection, but we have few insight

204 ere, we propose a systematic scheme based on iterations of optimal experiment design, flow cytometry

205 We refine the model through further iterations of perturbation and global measurements, sugg

206 Arg-Arg-Arg-Arg-Arg-Arg or longer iterations of polyarginine have been shown to be competi

207 esize (R)-monocillin II with four additional iterations of polyketide elongation, indicating the C2'

208 ile with results from later (most sensitive) iterations of PSI-BLAST provides a better discriminator

209 corruption frequently observed in the later iterations of PSI-BLAST searches.

210 In another example, several iterations of PSI-BLAST were required to demonstrate tha

211 ing a modified Delphi approach with multiple iterations of questionnaires to reach consensus on new c

212 Six iterations of questionnaires were required to reach cons

213 ity may enable building specificity into new iterations of Ras and other GTPase inhibitors.

214 After three iterations of refinement, the model was based on 48 vali

215 Successive iterations of screening and refining the method defined

216 ed databases at this stage, requiring manual iterations of sequence refinement in many cases.

217 SRs) in DNA sequences are composed of tandem iterations of short oligonucleotides and may have functi

218 Through iterations of software release and user feedback, new fe

219 e production in S. cerevisiae often requires iterations of strain modifications and metabolite analys

220 imelate, and 2-oxosuberate, completing three iterations of the 2-oxoacid elongation pathway.

221 A total of 250 iterations of the algorithm were performed to determine

222 ensures the persistence of provenance across iterations of the analysis, with changes automatically m

223 chers, and designers with over 20 successive iterations of the decision aid, which were field tested

224 Finally, lessons learned during iterations of the design-build-test-learn cycle can serv

225 We determined that several iterations of the discriminant analysis improved the cla

226 of the risk assessment tools so that future iterations of the estimators can be improved to more acc

227 Multiple iterations of the genetic algorithm yielded a consistent

228 te the importance of considering alternative iterations of the genetic code.

229 The various iterations of the HapMap Project and many genome-wide as

230 Using repeated iterations of the iTILLING process, mutations in three o

231 e to ensure that vectors designed with early iterations of the language are consistent with the lates

232 Aggregating 500 iterations of the model reveals a high-resolution flow n

233 We analyzed 9 iterations of the National Health Interview Survey, an a

234 category which should be redefined in future iterations of the recommendations.

235 population abundance produced by independent iterations of the same processes in different regions sh

236 Future iterations of the wGRS might therefore make a contributi

237 After 4 to 15 iterations of this enrichment process, suppressor mutant

238 ture into dendritic branches, and successive iterations of this process result in growth and branchin

239 Iterations of this process will lead to affinity maturat

240 Multiple iterations of this reduction strategy are described, and

241 ore than 1,000 mRNAs, which contain multiple iterations of UAAU-binding elements.

242 ents complete several design-synthesize-test iterations on medicinal chemistry projects where they ca

243 th 28 subsets and 2 (OSEM2), 6 (OSEM6), or 8 iterations (OSEM8), and a 10-mm postreconstruction smoot

244 e, a potent mixture was identified in thirty iterations out of a possible million combinations of six

245 Only tens of iterations out of one hundred thousand possible trials w

246 erferon (IFN-gamma), with approximate weekly iterations over an 8-week period.

247 Through MISST search iterations, over 38,000 Prx sequences were identified, w

248 ion, and is robust with respect to choice of iteration parameters for a wide range of proteins.

249 ) + N.k(2).(d + log k), with T the number of iterations performed.

250 t removal but applies an additional level of iteration, permitting real signals to be distinguished f

251 eps of the algorithm that could redirect the iteration process away from the biologically relevant po

252 The iteration process is explicit and easy to program.

253 The iteration process of the EE algorithm is implicit.

254 he N-terminus of AurA is not involved in the iteration process, ruling out an ACP-ACP shuttle.

255 imated QTL parameters as a by-product of the iteration process.

256 distant homologues first detected by a third iteration PSI-BLAST search.

257 s, extended follow-up, and continuous device iteration remain essential to improve BVS technology.

258 statistical noise due to a higher number of iterations required for convergence.

259 We describe two iterations: RRes_EPA in which seeds contain EPA levels o

260 d iteratively, with products of all previous iterations serving as reactants for the next.

261 ested in ongoing trials, and the most recent iterations show therapeutic activity.

262 Six different iterations steps were utilized to systematically vary th

263 ced to approximately 1 s, enabling many more iterations than was previously believed possible, consis

264 y criterion which is tested during numerical iteration that allows us to decompose data when the numb

265 d sequence of AgSF1 reveals pentameric QPGSG iterations that are similar to conserved modular element

266 Its current iteration, the Fellowship Council, is in the process of

267 tic sensitivity analysis in about 60% of the iterations, the combined use of PET and MRI was superior

268 After trial and error iterations, the optimal formulae were %FEV(1)/FVC = 98.8

269 Each segment consists of a number of iterations; the first few iterations use an invariant en

270 iately after inserting the lesion and in all iterations thereafter.

271 Our fast methods avoid iteration through a careful use of information about the

272 rk, we show that in the standard approach of iteration through all triangles of SymBets, the memory s

273 be run in the laboratory to facilitate rapid iteration through biological experiments.

274 omes), and construction time scales with the iteration through each pair, i.e. O(g(6)).

275 substitutions, and it was isolated after two iterations through the two-tiered approach.

276 Standard techniques often rely on iteration to converge to the solution of a discretized v

277 ithm compares resultant hits from the second iteration to the final iteration of a PSI-BLAST search,

278 olution of a synthetic route through several iterations to a final practical and scaleable synthetic

279 take an exponentially long (in N) number of iterations to converge to the posterior distribution.

280 ilizes the E-values from these two PSI-BLAST iterations to obtain a figure of merit for rank-ordering

281 th random input data, the time (or number of iterations) to convergence (within a given tolerance) is

282 the number of intermediate solutions at each iteration, to solve the two models, respectively.

283 Robot-assisted surgery is the latest iteration toward less-invasive surgical procedures.

284 sts of a number of iterations; the first few iterations use an invariant encoding, while the remainde

285 the measurement accuracy were the number of iterations used for reconstruction and the postfiltering

286 Further iterations using the Flow-IEG system enable an exponenti

287 In a series of iterations, we analyzed all their suggestions to identif

288 Through prototype iterations, we have developed a versatile high-resolutio

289 With two iterations, we were able to reduce errors in synthetic g

290 t eliminating clusters of structures at each iteration, which are unlikely to be of similar fold to t

291 erated the PME value of 21.82 at 48169 epoch iterations, which is significantly improved from the PME

292 The resulting model involved 16 tomographic iterations, which required 6800 wavefield simulations an

293 uencing data 2-fold compared to the previous iteration, while simultaneously increasing the percentag

294 The use of a matrix-free Newton iteration with a finite element scheme for the nutrient

295 DACTAL combines iteration with a novel divide-and-conquer approach, so t

296 A composite model from 200 random iterations with 25% of the molecules in each case yielde

297 Because 2-5 iterations with 8-28 subsets are being used in clinical

298 plateaued faster as a function of number of iterations with TOF than non-TOF.

299 different combinations and, using numerical iterations within a classical population-genetic framewo

300 ral approaches were undertaken with multiple iterations, yielding Catalyst 3D-QSAR models being able