ライフサイエンスコーパス: jejunal

1 Attenuation of collapsed jejunal (134 HU) and ileal (108 HU) loops was greater th

2 Expression levels of the jejunal Abcg5 (ATP-binding cassette transporter G5) and

3 effects of oleic acid and ricinoleic acid on jejunal absorption, steady-state jejunal perfusions were

4 umen perfusion catheter, we investigated the jejunal absorption, systemic availability, metabolism, a

5 Multiunit recordings of jejunal afferent activity were made using extracellular

6 Responses of rat jejunal afferent fibers were examined by electrophysiolo

7 SLIGRL-NH2 (0.001-1 mg kg-1, I.V.) increased jejunal afferent firing and intrajejunal pressure.

8 Colonic and jejunal afferent mechanosensory function was attenuated

9 s this issue, we examined the sensitivity of jejunal afferent nerves to a hexapeptide agonist of PAR2

10 te the contribution of the TRPV1 receptor to jejunal afferent sensitivity in the murine intestine.

11 t2 deficiency is associated with exaggerated jejunal afferent sensitivity to both mechanical and chem

12 The WT jejunal afferents responded to capsaicin with rapid incr

13 weeks after implantation, side-to-side cyst-jejunal anastomoses were fashioned in one cohort of rats

14 onstruction via either end-to-side Roux-en-Y jejunal anastomosis or direct duodenal anastomosis.

15 Messenger RNA (mRNA) from jejunal and colonic mucosa was isolated, and transcript

16 h regard to the induction of swelling of the jejunal and colonic organoids.

17 Deletion of Gata6 and Gata4 resulted in a jejunal and duodenal phenotype that was nearly identical

18 MTX-ARG rats demonstrated greater jejunal and ileal bowel weight, greater ileal mucosal we

19 coli, the numbers of E. coli cells in their jejunal and ileal lavage fluid are significantly increas

20 HU) loops was greater than that of distended jejunal and ileal loops (P < .001).

21 was measured in the distended and collapsed jejunal and ileal loops and in the terminal ileum.

22 Jejunal and ileal luminal BAs, portal blood BAs, and mes

23 crypt depths were increased in the duodenal-jejunal and ileal remnants of both genotypes.

24 ections, adaptation was analyzed in duodenal-jejunal and ileal segments from C57BL/6 Bax(+/+) (16, 48

25 Jejunal and ileal specimens from normal control dogs (n=

26 Jejunal and ileal tissues were taken before harvesting,

27 Patients with jejunal and ileocecal NETs who were treated at the Moffi

28 In human jejunal and rat and guinea pig colonic segments, additio

29 on to liver, GSH levels in kidney, duodenal, jejunal, and ileal mucosa of EHBR were 200% to 300% of a

30 n was high in the apical region of duodenal, jejunal, and ileal villus epithelial cells; low in absor

31 olitis, hyperplasia, diarrhea, and mistarget jejunal apical markers.

32 Jejunal apoA-I synthesis and plasma apoA-I levels were i

33 At enteric phase CT enterography, jejunal attenuation is greater than ileal attenuation an

34 Furthermore, organ cultures of jejunal biopsies from 28 CD patients were set up to asse

35 Similar lesions are evident in jejunal biopsies from EPEC-infected children.

36 Jejunal biopsies from volunteers challenged with Cryptos

37 Jejunal biopsies showed an altered mucosal architecture

38 Proximal jejunal biopsies were obtained after the supplementation

39 cent to adherent organisms was observed in a jejunal biopsy from a volunteer who ingested the wild-ty

40 ody tests to determine if they could replace jejunal biopsy in patients with a high pretest probabili

41 We analyzed longitudinal jejunal biopsy samples from HIV-1-infected patients, dur

42 Evaluation of jejunal biopsy samples from long-term HIV-1-infected non

43 Jejunal biopsy specimens from patients with gluten-sensi

44 hemokines and cytokines in cell lysates from jejunal biopsy tissues were assayed by a 22-multiplex be

45 A full thickness jejunal biopsy was obtained from a 38-year-old insulin-d

46 Jejunal biopsy would be necessary in patients with disco

47 of the SMV, in the rare setting in which the jejunal branch is preserved, may also be managed by liga

48 Isolated involvement of the jejunal branch of the SMV may be managed by division of

49 2 primary branches of the SMV (the ileal and jejunal branches), with or without involvement of the ma

50 e randomly assigned to five groups: duodenal-jejunal bypass (DJB), jejunal resection (jejunectomy), i

51 iables of rats that had undergone a duodenal-jejunal bypass (DJB).

52 endoscopic implant that mimics the duodenal-jejunal bypass component of the Roux-en-Y gastric bypass

53 Duodenal-jejunal bypass group showed greater reductions in fastin

54 Duodenal-jejunal bypass improved insulin sensitivity and beta-cel

55 he safety and efficacy of 6 months' duodenal-jejunal bypass liner (DJBL) treatment in comparison with

56 or the rapid antidiabetic effect of duodenal jejunal bypass surgery.

57 makes no more than a minimal contribution to jejunal Ca(2+) absorption at luminal concentrations prev

58 pression in peripheral blood CD4(+) T cells, jejunal CCR5(+) CD4(+) T cells exhibited significantly l

59 Jejunal CCR5(+) CD4(+) T cells exhibited the highest lev

60 arboxypeptidase cDNA was isolated from a pig jejunal cDNA library using an amplified homologous probe

61 s of both jejunum and colon, and accelerated jejunal cell migration.

62 e in vivo basal and prostaglandin-stimulated jejunal chloride secretion in normal subjects, CF hetero

63 d mean luminal [Cl(-)] of postprandial human jejunal chyme, and reflects contributions from both tran

64 ated an association between a suppression in jejunal circular muscle activity and a massive extravasa

65 of COX-2, we observed a decrease in in vitro jejunal circular muscle contractility and gastrointestin

66 tinal transit assessed in vivo motility, and jejunal circular muscle contractility was measured in vi

67 Jejunal circular muscle contractions were measured in an

68 Spontaneous and bethanechol-stimulated jejunal circular muscle contractions were measured in an

69 l muscularis and a functional suppression in jejunal circular muscle contractions.

70 rophils into the muscularis and also averted jejunal circular muscle dysfunction.

71 Leukocyte infiltration and in vitro jejunal circular muscle function were quantified in cont

72 el calcium currents were measured from human jejunal circular smooth muscle cells in response to incr

73 ensitive calcium channel is present in human jejunal circular smooth muscle cells.

74 s of fluoxetine on isolated canine and human jejunal circular smooth muscle cells.

75 etine had direct effects on canine and human jejunal circular smooth muscle cells.

76 Organ bath experiments were performed on jejunal circular smooth muscle strips.

77 on, gastric acid secretion, and cAMP-induced jejunal Cl- secretion.

78 ictures) were fewer in the duodenal than the jejunal cohort (7 patients [12%] vs 13 [35%]; P = .009).

79 Of patients with stricture, 5 of 9 in the jejunal cohort required percutaneous transhepatic access

80 The jejunal conduit was passed through a substernal route in

81 ssociated suppression of in vitro muscarinic jejunal contractility.

82 obestatin suppressed food intake, inhibited jejunal contraction, and decreased body-weight gain.

83 Spontaneous jejunal contractions were markedly suppressed in UP-LPS-

84 NKCC1 mRNA was found to be expressed in rat jejunal crypt but not villus cells.

85 imorphism in the extent of radiation-induced jejunal crypt cell apoptosis, with female mice having hi

86 rence in susceptibility to radiation-induced jejunal crypt cell apoptosis.

87 Jejunal crypt cell survival was decreased in those mice

88 id not appreciably alter radiation damage to jejunal crypt cells and tissue involved in the developme

89 Jejunal crypt cells undergo apoptosis in response to ion

90 Published human jejunal data (119 P(eff), 53 compounds) were analyzed by

91 Human jejunal digests after oral ingestion of casein and whey

92 terioration in his general condition, showed jejunal dilatation, intestinal intramural gas, portomese

93 unum of transgenics than wild-type mice, but jejunal disacharidase activities were not increased.

94 ollow up both Crohn disease patients without jejunal disease and in pediatric patients where nasogast

95 d to present a 67-year-old male patient with jejunal diverticulitis accompanying with abdominal pain

96 ral surgery department with the diagnosis of jejunal diverticulitis.

97 Jejunal diverticulosis is a rare, usually asymptomatic d

98 Duodenal, mid-jejunal effluents and plasma samples were collected at d

99 on average, a nearly 2-fold accumulation of jejunal endocannabinoids, whereas emulsions containing s

100 id revealed patchy infection of duodenal and jejunal enterocytes of 18 of 31 HuNoV-inoculated pigs wi

101 Intracellular pH was measured in jejunal enterocytes of wild-type mice and mice with disr

102 C1 Like 1 (NPC1L1) is a protein localized in jejunal enterocytes that is critical for intestinal chol

103 ption, was also dramatically up-regulated in jejunal enterocytes upon exposure to LXR agonists.

104 TMs were extracted from colonic and jejunal epithelial cells and smooth muscle, and hTM isof

105 he major hTM isoforms present in colonic and jejunal epithelial cells are hTM5 and hTM4, whereas inte

106 -beta(1) are constitutively expressed in the jejunal epithelial compartment in uninfected mice and du

107 Here we show that primary intestinal (jejunal) epithelial cells express galactosylceramide, an

108 MCT feeding stimulated jejunal-epithelial thymic stromal lymphopoietin, Il25, a

109 aepithelial nematode Trichinella spiralis in jejunal epithelium from BALB/c mice.

110 thelial lining was not affected, whereas the jejunal epithelium was seriously damaged.

111 ralis induces changes in the proteome of the jejunal epithelium, including substantial up-regulation

112 nctionally distinct cell types of the murine jejunal epithelium.

113 ation; and feeding intolerance necessitating jejunal feeding (n = 8, 20%) due to delayed gastric empt

114 Enteral nutrition with gastric or jejunal feeding in healthy young men results in similar

115 Jejunal feeding is preferred instead of gastric feeding

116 teral nutrition as either gastric feeding or jejunal feeding on endocrine responses in vivo in humans

117 act of gastric feeding compared with that of jejunal feeding on postprandial circulating plasma gluco

118 Jejunal feeding resulted in higher peak plasma insulin c

119 e 2 (GLP-2) concentrations was greater after jejunal feeding than after gastric feeding, with higher

120 Studies on percutaneous jejunal feeding tubes demonstrate: high complication rat

121 on can also be iatrogenic from intracatheter jejunal feeding tubes, stent perforation, sclerotherapy,

122 nd GLP-2 concentrations being attained after jejunal feeding.

123 of 51 patients who underwent a supercharged jejunal flap for total esophageal reconstruction between

124 n the stomach is unavailable, a supercharged jejunal flap may reestablish alimentary tract continuity

125 The discovery of the jejunal folylpoly-gamma-carboxypeptidase gene provides a

126 Jejunal folylpoly-gamma-glutamate carboxypeptidase hydro

127 rostate-specific membrane antigen and to the jejunal folylpoly-gamma-glutamate carboxypeptidase.

128 data demonstrate that GATA4 is essential for jejunal function including fat and cholesterol absorptio

129 ctor GATA4 has been implicated in regulating jejunal gene expression, the contribution of GATA4 in co

130 in levels in recipients of orthotopic Wistar jejunal grafts (group 4).

131 of contrast material to the skin in 11 (4%), jejunal hematomas in five (2%), and intussusceptions in

132 h or without IGF-I (800 micrograms/day), and jejunal histology and epithelial ion transport were meas

133 apture microdissection and gammadelta TCR(+) jejunal IELs purified by flow cytometry disclosed that t

134 Strain 042 adhered strongly to samples of jejunal, ileal, and colonic mucosa.

135 al tissues, including the colorectal, cecal, jejunal, ileal, duodenal, and cecal tonsil tissues.

136 introduced a TNM staging classification for jejunal-ileal (midgut) neuroendocrine tumors (NETs).

137 85% of the small intestine and regulates the jejunal-ileal gradient in absorptive enterocyte gene exp

138 of Gata4 is critical for the maintenance of jejunal-ileal homeostasis in the adult small intestine i

139 ional signal required for the maintenance of jejunal-ileal identities in the adult mouse small intest

140 ge of the patients was 43 years, the average jejunal-ileal length was 23 cm, and the average length o

141 Forty-five TPN-dependent adults with a jejunal-ileal remnant < or = 50 cm and a portion of colo

142 We identified 691 patients with jejunal-ileocecal NETs.

143 acteristics of this inhibition are: 1) local jejunal inflammation induced by T. spiralis systemically

144 fasting for 72 h and subsequent refeeding or jejunal infusion of long-chain triglyceride (LCT) for 24

145 Dietary sodium restriction also increased jejunal interstitial fluid cGMP and fluid absorption.

146 unctionally distinct cell types of the mouse jejunal intestinal epithelium and that miRNAs respond to

147 motic leaks and strictures, marginal ulcers, jejunal ischemia, small bowel obstruction, internal hern

148 o draw comparisons between human colonic and jejunal ischemia-reperfusion sequelae in a human in vivo

149 Native jejunal (J) and non-anastomosed (N-N) and anastomosed (A

150 We compared the results of jejunal (JBx) and ileal (IBx) biopsies after bowel trans

151 The duodenum and duodenal-jejunal junction are often malpositioned in children wit

152 t runs parallel to the gut from the duodenal-jejunal junction to the cloaca.

153 ce and position of the duodenum and duodenal-jejunal junction were recorded.

154 The duodenum and duodenal-jejunal junction were visualized on anteroposterior spot

155 Rat IL-15 was cloned from a rat jejunal library.

156 s was investigated using an in vivo isolated jejunal loop model of intestinal ischemia-reperfusion.

157 ed stomach, proximal efferent loop, oversewn jejunal loop, and distal jejunojejunal anastomosis were

158 unidirectional efflux (absorption) from the jejunal loop.

159 labeled glucose transport were determined in jejunal loops and in mice following apelin gavage.

160 ux through the gastric epithelial barrier in jejunal loops and in vivo following oral glucose adminis

161 Distended jejunal loops had significantly greater attenuation than

162 t and consumption were assayed using ex vivo jejunal loops.

163 ly disease, particularly at the level of the jejunal loops.

164 v-specific MHC class I restricted CTL in the jejunal LP.

165 entrations of sugars similar to those in the jejunal lumen immediately after a meal, is severalfold g

166 m, fascia, explant and donor liver bile, and jejunal lumen in 77 liver transplantations, and we monit

167 Jejunal luminal BA levels were similar between animals w

168 increased Hsp25 and Hsp72, but not Hsc73, in jejunal lymphocytes and epithelial cells.

169 levels of peripheral blood eosinophilia and jejunal mastocytosis occurred in wild-type and IgE-defic

170 These data suggest that jejunal MC sequentially express mMCP-2, cease expressing

171 Thus, the ability of a jejunal MC to reversibly alter its tryptase expression d

172 ring the recovery phase of the inflammation, jejunal MCs cease expressing mMCP-2 and then express var

173 the helminth-induced inflammation, when the jejunal MCs move from the submucosa to the tips of the v

174 In noninfected mice, most jejunal MCs reside in the submucosa and express mMCP-6 a

175 from the jejunum supports the view that many jejunal MCs translocate to the spleen during the recover

176 g this translocation process, some senescent jejunal MCs undergo nuclear segmentation.

177 was studied by extracellular recordings from jejunal mesenteric afferent bundles and patch clamp reco

178 nnervation was examined in the external ear, jejunal mesenteric arterioles, superficial epigastric, f

179 cell depletion, such as dysregulation of the jejunal microenvironment after SIV infection, likely acc

180 somewhat lower than, that observed in human jejunal microsomes (7.4-15.4), which may reflect the pre

181 ne gastric mucin (pPGM) and purified porcine jejunal mucin (pPJM).

182 ated to be somewhat lower than that of human jejunal mucosa (1.14 and 3.67 ml/min/g of cells, respect

183 ) mice, eosinophils are not recruited to the jejunal mucosa after infection and are not present in th

184 nd mast cells were markedly increased in the jejunal mucosa during primary infections with S. venezue

185 luated the regulation of CYP3A5 in liver and jejunal mucosa from white donors.

186 Using in vivo microscopy to image jejunal mucosa of GFP gammadelta T-cell transgenic mice,

187 rhesus enteric alpha-defensins (REDs) in the jejunal mucosa of rhesus macaques during all stages of S

188 rs that gliadin is not directly toxic to GSE jejunal mucosa per se, but rather toxicity requires the

189 The response of the jejunal mucosa to a known cathartic provides observation

190 No abnormality of jejunal mucosa was detected histologically in five patie

191 1c/123(-) CD13(+) CD14(-) macrophages in the jejunal mucosa were infected, albeit at lower levels tha

192 induced differential growth of duodenal and jejunal mucosa.

193 ry is based primarily on in vitro studies of jejunal mucosa.

194 detected two cytosolic beta-glucosidases in jejunal mucosa.

195 PCR revealed the presence of Ca(v)beta(3) in jejunal mucosa; Western blotting and immunocytochemistry

196 Jejunal mucosal mass was 30% greater with MCTs plus LCTs

197 le proteases that are readily seen in mature jejunal mucosal MC that also are induced by the infectio

198 villi until the proximal to mid jejunum and jejunal mucosal ulcerations.

199 Rats given TPN with IGF-I had greater jejunal mucosal weight, greater protein and DNA content,

200 at would sum with responses of ICC in intact jejunal muscle strips.

201 iptase-polymerase chain reaction (RT-PCR) in jejunal muscle, whereas 5-HT(1A), 5-HT(1D), and 5-HT(2C)

202 f Ca(2+) transients in ICC-DMP within intact jejunal muscles expressing a genetically encoded Ca(2+)

203 ave amplitude, however, were noted in intact jejunal muscles that were not observed in ICC.

204 copGFP(+) cells from jejunal muscles were Kit(+) and free of contaminating ce

205 tochemistry for neutrophils was performed in jejunal muscularis whole mounts.

206 ) decreased neutrophil infiltration into the jejunal muscularis; and (3) prevented SITx-induced suppr

207 A1R is expressed in jejunal myenteric neurons and colonic submucosal neurons

208 nic myocytes possess densities twice that of jejunal myocytes.

209 v4-like immunoreactivity was less evident in jejunal myocytes.

210 of the KChIP family in isolated colonic and jejunal myocytes.

211 At laparotomy, extensive jejunal necrosis required bowel resection, jejunostomy,

212 In conclusion, neurons in Remak's juxta-jejunal nerve appear to regulate gut motility.

213 alpha-MD-G-stimulated jejunal NHE3 activity was defective in NHERF2-/- mice an

214 te alpha-methyl-D-Glu (alpha-MD-G) activated jejunal NHE3; this process required Akt and NHERF2.

215 No intact casein was detected in the jejunal nor in the in vitro samples taken during the int

216 Additionally, jejunal nutrient sensing and leptin action are demonstra

217 In contrast, jejunal nutrient sensing inhibits glucose production and

218 fined; intestinal absorption was assessed by jejunal or ileal perfusion studies.

219 on of hemorrhagic luminal fluid in duodenal, jejunal, or ileal loops treated for 6 h with purified CP

220 ed treatment algorithms for NETs of ileal or jejunal origin and of pancreatic origin are presented.

221 In both models jejunal perfusion was used to assess absorption.

222 eic acid on jejunal absorption, steady-state jejunal perfusions were performed in healthy volunteers.

223 The study aimed to predict effective human jejunal permeability (P(eff)) using a biophysical model

224 The biophysical model predicted human jejunal permeability data within the experimental uncert

225 on, the contribution of GATA4 in controlling jejunal physiology has not been addressed.

226 Eligible participants had jejunal placement of a percutaneous gastrojejunostomy tu

227 In vitro mouse colonic and jejunal preparations with attached splanchnic and mesent

228 eroglucagon and GLP-I levels correlated with jejunal proglucagon mRNA.

229 59 duodenal reconstructions and 37 Roux-en-Y jejunal reconstructions.

230 n routes in bronchoalveolar lavage fluid and jejunal, rectal, and vaginal tissue samples.

231 five groups: duodenal-jejunal bypass (DJB), jejunal resection (jejunectomy), ileal resection (ileect

232 Both DJB and jejunal resection normalized SI in diabetic rats as show

233 At laparotomy, rats had jejunal sacs filled with (glucose + alanine), glucose, g

234 protein expression levels were increased in jejunal samples following C. parvum infection and were a

235 Jejunal samples from macaques before and after Cryptospo

236 ile beta-lactoglobulin was found in one hour-jejunal samples in agreement with the in vitro digestion

237 exposed to 10 mmol/L theophylline to induce jejunal secretion.

238 Immunohistochemistry of jejunal sections with a rabbit polyclonal Ab to Xenopus

239 ducing cells compared with the corresponding jejunal segment of controls.

240 -)-epicatechin was perfused into an isolated jejunal segment together with antipyrine as a marker for

241 eight conjugated bile acids from a perfused jejunal segment was measured in the anesthetized biliary

242 Rat jejunal segment was subjected to ischemia for 30 minutes

243 engthening device was inserted into isolated jejunal segments in pigs, and fully expanded over 8 days

244 Jejunal segments isolated from Trichinella spiralis-infe

245 To evaluate cytotoxicity, jejunal segments of the anesthetized rat were exposed to

246 re made from mesenteric afferents from mouse jejunal segments perfused in vitro.

247 tochemistry for neutrophils was performed in jejunal segments.

248 Jejunal SOCS (SOCS-1, -2, -3, and cytokine-inducible SH2

249 GH, but not IGF-I, induced jejunal SOCS-2 mRNA.

250 4 null jejunum lost expression of 53% of the jejunal-specific gene set and gained expression of 47% o

251 (mMCP) 9, essentially all of the MCs in the jejunal submucosa and spleen of T. spiralis-infected mic

252 transcript and protein were observed in the jejunal submucosa of Trichinella spiralis-infected BALB/

253 A3R IR occurs in 57% of substance P-positive jejunal submucosal neurons (putative intrinsic primary a

254 Jejunal sucrase activity (in U/cm) was significantly gre

255 Rats were euthanized to harvest jejunal tissue for histology and cytokine profiles by EL

256 rs cyclin D1 and cyclin D2 were decreased in jejunal tissue in septic transgenic mice.

257 used rises in short circuit current from rat jejunal tissue mounted in a Ussing chamber and rounding

258 cuit current and potential difference in rat jejunal tissue mounted in Ussing chambers.

259 we studied SP mRNA and protein expression in jejunal tissue samples of patients with AIDS with natura

260 reduced STa-provoked anion secretion in pig jejunal tissue, and fluid retention and cGMP levels in S

261 antitative PCR indicated that in colonic and jejunal tissue, Kv4.3 transcripts demonstrate greater re

262 Here we use electron tomography to make jejunal transcytosis visible directly in space and time,

263 the bilirubin-lowering effect of heterotopic jejunal transplants (group 2).

264 es, the authors have shown that 15- to 20-cm jejunal transplants from normal Wistar rats lowered but

265 henobarbital treatment of Gunn recipients of jejunal transplants from Wistar rats normalizes serum bi

266 Forty-three Gunn recipients of jejunal transplants from Wistar rats were divided into f

267 upon nutritional rehabilitation with either jejunal tube feedings or parenteral nutrition until weig

268 Continued evaluation of endoscopic jejunal tube placement methods and associated clinical o

269 ings as compared with bedside self-migrating jejunal tubes in patients with severe acute pancreatitis

270 tion, lymphangioma) were identified, but two jejunal tumors were not detected in a patient with poor

271 infarction developed refractory duodenal and jejunal variceal bleeding as a result of diffuse viscera

272 2; middle colic vein (MCV), in 29; and first jejunal vein (FJV), in 36.

273 Jejunal villar epithelial and hepatocellular necrosis we

274 m, whereas apoptosis was clearly observed in jejunal villi and crypts, (42 times more M30 positivity

275 ice exhibited a 2-fold increase in length of jejunal villi and have normal growth on a normal diet bu

276 Capillaries in jejunal villi can absorb nutrients at rates several hund

277 ed over an anatomically correct model of rat jejunal villi.

278 Intracellular pH (pH(i)) of intact jejunal villous epithelium was measured by ratiometric m

279 itative reverse transcriptase-PCR studies of jejunal villus epithelium recovered from germ-free trans

280 c epithelial lining, but extensive damage in jejunal villus tips after 60 minutes ischemia.

281 at GATA4 plays a pivotal role in determining jejunal vs ileal identity.

282 Anti-CD3 mAb increased jejunal wt/l ratios by more than 50% at 3 hours, returni