ライフサイエンスコーパス: joint effect

1 tify the optimal tree model representing the joint effect.

2 nd that the combination of both results in a joint effect.

3 , but at a cost of flexibility in models for joint effects.

4 exposures and now flexibly assess models for joint effects.

5 two inputs by measuring their individual and joint effects.

6 as nonlinear, interactive, correlative, and joint effects.

7 t was additive (complementary) for peak VO2 (joint effect, 2.5 mL/kg/min).

8 In assessing joint effects, addition of CRP to standard lipid screeni

9 Moreover, we observed a joint effect among the TM6SF2 rs58542926, the PNPLA3 rs7

10 otype frequency, effect sizes, and models of joint effects among genetic variants on lifetime risk es

11 In joint-effects analyses, compared with women with high di

12 om 2.3 for 1 to 10.0 for 4 risk alleles in a joint effect analysis of Age-Related Maculopathy Suscept

13 on assumptions of additive or multiplicative joint effects and breast cancer incidence rates.

14 e models capable of both characterizing such joint effects and providing new insight into pathogenesi

15 s employed to identify the models with locus joint effects, and interaction was further verified by c

16 s, we show that the same isobole pattern and joint effects are generated by modeled combinations of f

17 Joint effects are notoriously hard to identify and chara

18 smoking separately increase risk, and their joint effects are particularly hazardous.

19 s an uncritical acceptance of multiplicative joint effect as the biologically meaningful no-interacti

20 nalysis refined the sJIA association, with a joint effect at rs1400986 and rs4129024 in intron 1 of M

21 as focused on methods that take into account joint effects at interacting loci.

22 synergism with family history of asthma, the joint effect being stronger with higher exposure levels.

23 There was a joint effect between the PNPLA3 and GCKR SNPs, explainin

24 Also observed were joint effects between gamma-radiation-induced increases

25 We also investigated potential joint effects between NO (2) exposure and ADRB2 5'-UTR m

26 In contrast, no joint effects between plasma levels of Lp(a) and other c

27 There were joint effects between the variant IL-6 genotypes and smo

28 multivariable-adjusted analyses considering joint effects by BMI and ARDI, compared with women with

29 These tests become less optimal if the joint effect cannot be approximated adequately by the ad

30 the authors conducted a ranking analysis of joint effects in which the sums and differences of the p

31 cy virus (HIV) treatment outcomes, yet their joint effect is not known.

32 Our first task, when studying joint effects, is to understand the limitations of our d

33 graphical interpretation: Curves of constant joint effect (isoboles) must be negatively sloped straig

34 rinsulinemia, but that their independent and joint effects may be associated with small increases in

35 The existing joint-effects methods also have limitations.

36 ypical estimates of mutation parameters, the joint-effect model can explain data from laboratory expe

37 the patterns of predicted responses for the joint-effect model now become close to those of the infi

38 basis of empirical knowledge of mutations, a joint-effect model of pleiotropic and real stabilizing s

39 lation at mutation-selection balance under a joint-effect model of real stabilizing and pleiotropic s

40 alysis did not provide clear support for the joint-effect model or a clear case for rejection.

41 ait, as supported by the available data, the joint-effect model predicts a significantly higher V (G)

42 ion, and a pleitropic effect on fitness (the joint-effect model).

43 pairs of markers and have not considered the joint effect of a group of markers beyond these pairwise

44 of this approach is that it cannot model the joint effect of a set of SNPs on a set of genes, which m

45 of this approach is that it cannot model the joint effect of a set of SNPs on a set of genes, which m

46 The results indicate a possible joint effect of activation ability of aerosol particles,

47 nondemented people, there is only a marginal joint effect of AD genes on memory independent from APOE

48 However, simultaneously modeling of the joint effect of all 61 SNPs in 7 nicotinic acetylcholine

49 cs at unmeasured eQTLs and (ii) test for the joint effect of all measured and imputed eQTLs in a gene

50 ed functional variants and (ii) test for the joint effect of all measured and imputed functional vari

51 if presence in large sequences, based on the joint effect of all such features.

52 The adjusted odds ratio for the joint effect of antecedent depression and chronic physic

53 Modeling the joint effect of bedding and bedroom floor endotoxin on r

54 rnel machine regression (BKMR), to study the joint effect of coexposure to arsenic, manganese, and le

55 The joint effect of coronary artery calcification-SNPs was a

56 The joint effect of DGI and obesity was also examined.

57 rsity among paleodrainages correspond to the joint effect of differences in the area encompassed by,

58 To study the joint effect of drug heterogeneity, growth rate, and evo

59 genes or haplotype blocks, then testing the joint effect of each SNP set.

60 ults are consistent with the hypothesis of a joint effect of estrogen receptor beta sequence variants

61 The idea is that if the joint effect of exposure and genotype on risk is submult

62 The joint effect of high DGI and obesity provided evidence o

63 However, the joint effect of hyperhomocysteinemia (HHcy) and hypergly

64 We aimed to assess the joint effect of in utero exposure to arsenic, manganese,

65 There was a joint effect of maternal and paternal age with increasin

66 il now, no models exist that can predict the joint effect of mixtures including synergists.

67 mple-specific information, and considers the joint effect of multiple enhancers.

68 gression model are widely used to assess the joint effect of multiple predictors on a disease outcome

69 small portion of variability in disease, the joint effect of multiple variants in a pathway on diseas

70 ependent effect of physical activity and the joint effect of physical activity and adiposity on HF ri

71 We examined the joint effect of retinal abnormalities and microalbuminur

72 However, the joint effect of risk variants identified subgroups of th

73 Since gene expression levels reflect the joint effect of several underlying biological functions,

74 The joint effect of silica and smoking was more than additiv

75 The joint effect of smoking and asbestos alone was additive

76 okers, and 1.97 (95% CI: 1.73, 2.22) for the joint effect of smoking and obesity on mortality.

77 This study examines the joint effect of substance abuse and medication noncompli

78 ociations between genetic risk scores of the joint effect of the SNPs and of all calcification were i

79 evidence for association was found when the joint effect of the two genes was considered.

80 is consistent with previous studies, and the joint effect of the two loci is still greater in the hig

81 Strikingly, in examining the joint effect of these alterations, we observed a >30-fol

82 The joint effect of total cholesterol SNPs, low-density lipo

83 In conclusion, a joint effect of two PSCA SNPs, rs2294008 and rs2978974,

84 en of disease and injury attributable to the joint effects of 20 selected leading risk factors in 14

85 odds ratios (ORs) and 95% CIs for AMD by the joint effects of 25(OH)D (<12, >/=12 to <20, >/=20 to <3

86 For the joint effects of 25(OH)D level and vitamin D intake, the

87 k estimates were dramatically increased with joint effects of 4 or more than 4 Markov Blanket genes.

88 ingle-marker analysis cannot accommodate the joint effects of a large number of markers.

89 The separate and joint effects of alcohol and smoking on incidences of li

90 an, we tested effects of individual alleles; joint effects of alleles at multiple loci; epistatic eff

91 sistant strain genome allows analysis of the joint effects of alleles of different loci in isolation,

92 was conducted to examine the individual and joint effects of ambient PM2.5 exposures and MPBMI on th

93 We estimated joint effects of antiretroviral therapy (ART) initiation

94 The joint effects of any 2 types of physical activity on HF

95 This variation resulted from idiosyncratic joint effects of assembly sequence, productivity and spe

96 We investigated independent and joint effects of B vitamin intake as well as two polymor

97 Joint effects of biological (parasite) and chemical (Se)

98 he associations between boron intake and the joint effects of boron intake and HRT on lung cancer ris

99 ary boron intake and lung cancer risk or the joint effects of boron intake and HRT use on lung cancer

100 logistic regression was used to estimate the joint effects of C-reactive protein elevations and dysli

101 Multivariate analysis of the joint effects of changes in the six chromosomal regions

102 literature, including assessment of possible joint effects of cigarette smoking and fine particulate

103 We explored the joint effects of cigarette smoking and PMRT on LC risk.

104 ,5-b]pyridine: dose-related variation in the joint effects of common dietary carcinogens.

105 ion-based cohort large enough to examine the joint effects of EBV with other factors including age, s

106 Our results draw attention to the joint effects of ecological and endogenous selection in

107 to examine the independent associations and joint effects of education and poverty with self-reporte

108 iologically motivated by our interest in the joint effects of epigenetic methylation loci and their a

109 esity, but few studies have investigated the joint effects of exposure to SHS and diet.

110 th malaria exposure, possibly because of the joint effects of gene conversion and balancing selection

111 riad design faces limitations when examining joint effects of genetic and environmental factors.

112 The joint effects of genetic, ocular, and environmental vari

113 We assessed the joint effects of germline genetic variations through a p

114 dified such that they accurately predict the joint effects of hitchhiking and background on linked, n

115 , surprisingly few studies have explored the joint effects of host and parasite richness on disease r

116 ious reports, we found no association of the joint effects of Leu271 and Thr541 (odds ratio, 1.04; 95

117 Joint effects of loss of ANXA7 and gain of EGFR expressi

118 Joint effects of mixtures containing pharmacologically d

119 Joint effects of mixtures with fenarimol, testosterone,

120 CTGDR method, we are able to account for the joint effects of multiple genes/SNPs, whereas most exist

121 the hierarchical structure, accommodates the joint effects of multiple markers, and is computationall

122 These estimates may represent the joint effects of multiple QTL within a single interval (

123 ood level determinations should consider the joint effects of non-stationary tides and mean sea level

124 ive in the present study was to estimate the joint effects of obesity and smoking on all-cause mortal

125 oled Analysis of Case-Control Studies on the Joint Effects of Occupational Carcinogens in the Develop

126 ural models, to identify the independent and joint effects of OST and HAART on all-cause as well as d

127 We determine the independent and joint effects of OST and HAART on mortality, by cause, w

128 ality and morbidity, after adjusting for the joint effects of patient age, weight, pre- and postopera

129 We examined the joint effects of personal preference of dietary treatmen

130 We quantified the individual and joint effects of PM2.5 exposure with MPBMI on COWO, defi

131 To gain a better understanding of the joint effects of purifying selection and population stru

132 The joint effects of red and orange microbial clusters were

133 are achieved in the year 2025, adjusting for joint effects of risk factors.

134 Similarly, multiple-SNPs analysis revealed joint effects of rs2134655, rs172677 and rs1079597, with

135 d rate of recombination, suggesting that the joint effects of selection and linkage are important in

136 e we report results of a study to assess the joint effects of selection, recombination, and gene flow

137 ompanying article, Turner et al. compare the joint effects of smoking and air pollution to make infer

138 Evaluating absolute risks resulting from the joint effects of smoking and genetic factors is critical

139 estimate odds ratios for the independent and joint effects of smoking and PMRT on risk of overall, ip

140 Adjusted odds ratios for the joint effects of smoking and PMRT were 10.5 (95% CI, 2.9

141 Results suggest joint effects of specific loci on 5q and 4q, with an ove

142 egression analysis examined the separate and joint effects of the antioxidants on the ratio of forced

143 ngestion rates, and growth) to the predicted joint effects of the mixed stressors based on the indepe

144 In multivariate analysis, the joint effects of the professional groups' scores were as

145 ssion model; recalibrating the intercept and joint effects of the prognostic factors; re-estimating a

146 tal disease burden in 2000 resulted from the joint effects of the risk factors considered.

147 However, data evaluating the joint effects of these 2 conditions on mortality are spa

148 Having a better understanding of the joint effects of these trends on longevity and quality o

149 In order to understand the joint effects of TNT and RDX on earthworms, an important

150 ration-addition concept accurately predicted joint effects of two different mixtures: one containing

151 Hepatocellular carcinoma may result from the joint effects of viruses and hepatotoxic chemical carcin

152 This study considered the separate and joint effects of vitamin C, vitamin E, beta-carotene, an

153 fied a module of 91 genes with a significant joint effect on childhood-onset asthma (P < 10(-5)).

154 However, all methods, including our own Joint Effect on Phenotype of eQTL/functional single nucl

155 We propose joint effect on phenotype of eQTL/functional SNPs associ

156 nes in the network are more likely to have a joint effect on the relevant biological processes.

157 However, race, sex, and SES had joint effects on adiposity levels.

158 To examine their joint effects on diarrheal disease and how these effects

159 ystems, and the emergent properties of their joint effects on insect herbivores inform theory on mult

160 s were conducted to test the hypothesis that joint effects on population growth rates could be predic

161 We also observed significant locus-locus joint effects on the risk, which may be mediated by the

162 Metrics of the impact of joint effects or comparisons of joint effects presented

163 Joint effect ORs were adjusted for age, smoking, iris pi

164 he impact of joint effects or comparisons of joint effects presented in units of absolute risk, such

165 tal asthma; and 12.69 (3.44-46.91) for their joint effect (relative excess risk due interaction, 9.08

166 onto the same dendrite would diminish their joint effect, resulting in sublinear summation.

167 esult, we identified 205 module genes with a joint effect significantly associated with schizophrenia

168 When testing against multiplicative joint effects, the case-only design offers excellent pow

169 dently related to AMD, with a multiplicative joint effect with genotype on AMD risk.

170 erodynamic diameter <2.5 mum; PM2.5) and its joint effect with the mother's prepregnancy body mass in

171 cularly commuting physical activity, and its joint effects with body mass index on colon cancer risk

172 and conducted analyses to investigate their joint effects with plasma and dietary markers of folate