ライフサイエンスコーパス: junction

1 ing adenocarcinoma of the gastro-oesophageal junction).

2 emical synapses and electrical synapses (gap junctions).

3 nergic synapses, including the neuromuscular junction.

4 d within motor neurons via the neuromuscular junction.

5 failure to develop a patent pelvic-ureteric junction.

6 back is a global effect on the intercellular junction.

7 c plasticity at the Drosophila neuromuscular junction.

8 ffectively forming a stretchable 1D Schottky junction.

9 tion hotspot was identified at the ORF1-ORF2 junction.

10 ription start site and the first exon-intron junction.

11 -X structure which has unpaired bases at the junction.

12 >1000 measurements for single molecule break junctions.

13 that VLDL can modulate and reduce atrial gap junctions.

14 -dextran 4 kDa, and mRNA expression of tight junctions.

15 n complex semiconductor materials and across junctions.

16 when studying the quantum radiation field in junctions.

17 AF2 and reduces E-cadherin-mediated adherens junctions.

18 patial distribution of reversed biased p-i-n junctions.

19 E) reestablished both proteins at the apical junctions.

20 n illumination, in symmetric single-molecule junctions.

21 xecutes its function by stabilizing adherens junctions.

22 cell interactions and inter-endothelial cell junctions.

23 was overcome by disruption of intercellular junctions.

24 helial monolayers with compromised cell-cell junctions.

25 m temperature in thousands of single-cluster junctions.

26 roperties and destabilization of endothelial junctions.

27 function provided by desmosomes and adherens junctions.

28 tin filaments, Kindlin-2 stabilizes adherens junctions.

29 urrent-voltage (I-V) traces across molecular junctions.

30 rgy dissipation characteristics of molecular junctions.

31 platinum metallic wires down to single-atom junctions.

32 infected cells through contact dependent gap junctions.

33 ganized and dictated by a series of Holliday junctions.

34 s the targeting of microtubules to cell-cell junctions.

35 recognized component of endothelial adherens junctions.

36 tion of the sinus of Valsalva or sinotubular junction (14.2% versus 6.7%, P<0.001) and diffuse dilata

37 RNA nanoparticles derived from the three-way junction (3WJ) of the pRNA from bacteriophage phi29 DNA

38 or metastatic gastric or gastro-oesophageal junction adenocarcinoma, an Eastern Cooperative Oncology

39 ive resection of gastric or gastroesophageal junction adenocarcinoma, Intergroup Trial 0116 (Phase II

40 y for high risk gastric and gastroesophageal junction adenocarcinoma: Demonstrated superior survival

41 is also required for regulation of adherens junction (AJ) stability and dynamics.

42 ma-catenin and actin, components of adherens junctions (AJ).

43 L was calculated by measuring cemento-enamel junction and alveolar crest distance.

44 Cracks originating from the dental-enamel junction and enamel tufts, crack deflections, and the in

45 ow pressure, density, grain boundary, triple junction and interface coherency affect the nucleus grow

46 rnessing the biology of endothelial adherens junction and opens a new avenue for drug delivery in a b

47 in exhibiting high affinity for the Holliday junction and promoting DNA bridging, condensation, and p

48 measured 15-20 mm caudal to the hepatic vein junction and recorded by bidimensional imaging on a subc

49 orm the GABA binding/channel gating coupling junction and the channel pore (T288N), which are functio

50 The three-way junction and the P1 switch helix of the two apo conforme

51 arity proteins such as DLG-1 within adherens junctions and at the apical surface, thereby generating

52 Thermal transport in individual atomic junctions and chains is of great fundamental interest be

53 In conclusion, MetS-VLDL modulates gap junctions and delays both atrial and ventricular conduct

54 We confirmed the presence of adhesive junctions and discovered the formation of desmosomes bet

55 g pathways regulating plasticity of adherens junctions and endothelial permeability.

56 activates RAC1 to drive assembly of adherens junctions and establish barrier function.

57 inhibition increased VE-cadherin at adherens junctions and increased endothelial dilatation in old, b

58 rm a blood-retina barrier by virtue of tight junctions and low transcytosis.

59 into mice leads to the redistribution of gap junctions and promotes ventricular tachycardia, showing

60 ng necessitates tissue-level polarization of junctions and the cytoskeleton through unknown mechanism

61 as assessed using simulated data sets of CSR junctions and then used for analysis of Smu-Salpha and S

62 on, persisted during partial blockade of gap junctions and were mediated, in part, by AMPAergic trans

63 priospinal projection network, neuromuscular junction, and central pattern generator, providing a pla

64 rge transfer across the MoB/g-C3 N4 Schottky junction, and increases the local electron density in Mo

65 hy, such as the precuneus, temporal parietal junction, and medial frontal cortices, there were large

66 g mechanism that drives assembly of adherens junctions, and confirm these findings in mouse models.

67 educed numbers of nodes, disrupted paranodal junctions, and mislocalized Kv1 K(+) channels.

68 -cells propagates to the delta-cells via gap junctions, and the consequential stimulation of somatost

69 ostsynaptic specializations of neuromuscular junctions are dramatically expanded, including the subsy

70 We demonstrate that microhomology-rich S-S junctions are enriched in cells in which Mbd4 is deleted

71 y through transcytosis, as specialized tight junctions are functional as early as vessel entry into t

72 trate that the distance over which molecular junctions are maintained is a measure of smear, and the

73 er, the morphology and distribution of ER-PM junctions are not well characterized.

74 Levels of active Rac1 at epithelial junctions are partially modulated via interaction with A

75 Cell junctions are scaffolds that integrate mechanical and ch

76 Intramolecular four-way junctions are structures present during homologous recom

77 and molecules in optical lattices, Josephson junction arrays, and certain narrow band superconductors

78 We investigated connexin-assembled gap junctions as an alternative route for discharging lactat

79 other mouse tissues (including the anorectal junction) as well as in the gastro-oesophageal junction

80 required for epidermal cell polarization or junction assembly, but rather is needed for proper junct

81 of Src and likely occur through an adherens junction associated complex.

82 report the creation of an ultimately-shallow junction at the surface of n-type silicon with excellent

83 nnels are efficiently trafficked to adherens junctions at intercalated discs.

84 xin 30 (Cx30) promoted formation of Cx30 gap junctions at points of contacts between adjacent non-sen

85 s PCNA sequestration likely exposed ds-ssDNA junctions at replication forks for XPA binding.

86 those measurements based on single molecule junctions at room temperature.

87 rategies to show that this squamous-columnar junction basal cell population serves as a source of pro

88 Here, we fabricate a multiferroic tunnel junction based on ferromagnetic La0.7Sr0.3MnO3 electrode

89 of crumbs function disrupts the apical cell junction belt and crumbs overexpression expands the apic

90 cytoplasmic dynein-1, which localizes to the junction between the ellipsoid and myoid, functions to s

91 of protein-protein complexes that bridge the junctions between neighboring cells.

92 t in fullerene and nonfullerene-based single-junction binary-blend OSCs.

93 ur results also imply that quantum wires and junctions can be isolated in line defects of other trans

94 ardiomyocytes via connexin-43-containing gap junctions, cardiac macrophages have a negative resting m

95 It is a cell-to-cell junction cardiomyopathy, typically caused by genetically

96 in humans, which are knock-outs for the gap-junction channels connexin 26 and connexin 30 genes, we

97 ntly inhibit Cx26-Asp50Asn expression in gap junction channels, reverting the dominant negative effec

98 a tool for similar exploration of other gap junction circuits.

99 ding rough contacts, given the statistics of junction clusters sizes.

100 aneous activity, cadherin expression and gap junction communication.

101 Here, we describe a single-molecule junction comprising a redox-active, atomically precise c

102 We report that the single-molecule junction conductance of thiol-terminated silanes with Ag

103 well explained in terms of the variation in junction conductance with V b .

104 ing potassium current (IK1) density, and gap junction conductance.

105 o demonstrated lowered expression of the gap junction connexin 43.

106 geographical location at the nucleus-vacuole junction contact site.

107 We also demonstrate that these new SR-TT junctions contain the molecular machinery that mediate S

108 high-frequency hearing, suggesting that gap junctions contribute to passive cochlear mechanics and e

109 This suggests that the right temporoparietal junction contributes to controlling selective auditory a

110 D RSA bone loss apical to the cemento-enamel junction corresponded to a CRR of 1:1, relating to mild-

111 A stimulated cAMP synthesis and enhanced gap junction coupling in a concentration-dependent manner.

112 link between adenosine receptors and the gap junction coupling in endothelial cells of the blood-brai

113 Although the increased gap junction coupling is cAMP-dependent, neither the protein

114 It is shown how reduced IK1 density and gap junction coupling, as observed in heart failure, increas

115 ) influx, which leads to the increase in gap junction coupling.

116 between transmission lobes across successive junctions creates a gate-tunable transport gap without s

117 ucing barrier integrity impairment and tight junction damage.

118 asis by promoting the disruption of adherens junctions, dedifferentiation, and an epithelial to mesen

119 ntacts from different connecting helices and junctions (DeltaGHJH) or from changes in the electrostat

120 ganization and integrity of epithelial tight junctions depend on interactions between claudins, ZO sc

121 a suppression of alpha-cell activity via gap junction-dependent activation of delta-cells.

122 which the local variance in tension between junctions determines whether actomyosin-based forces wil

123 ves VE-cadherin endocytosis and pathological junction disassembly associated with the endothelial-der

124 endothelial cell contractility and adherens junction disassembly leading to endothelial barrier brea

125 llular ion transport and cause a novel tight junction disease characterized by a non-BS, non-GS autos

126 ) and BTB function (i.e., basal ES and tight junction disruption, making the barrier leaky), in the t

127 evented mucosal barrier disruption and tight junction downregulation in a mouse model of house dust m

128 u were formed at grain boundaries and triple junctions due to their limited plasticity.

129 ratio seen at low salt indicate the four-way junction exists as a mixture of conformations, one of wh

130 m using outlier statistics on RNA-sequencing junction expression identified 109 splicing events, whic

131 nexin family of membrane proteins enable gap junction formation and homeostasis, supporting communica

132 importantly, in addition to positive triple junction formation energies we also find a significant n

133 ation with its cognate receptor is vital for junction formation in the invasion process.

134 idual cells, lateral migration and cell-cell junction formation precede matrix invasion.

135 Endothelial cell intercellular junction formation was characterized by immunostaining.

136 s in zebrafish, Danio rerio, require two gap-junction-forming Connexins for formation and function.

137 d for analysis of Smu-Salpha and Smu-Sgamma1 junctions from CH12F3 cells and primary murine B cells,

138 Removing the branched network junctions from the analysis caused a slight increase in

139 es only hearing loss, exhibited impaired gap junction function and showed no transdominant interactio

140 N-cadherin internalization and abnormal cell junctions, generating an ectopic neuronal layer that res

141 junctional protein innexin shaking-B to gap junctions (GJs).

142 chronization of myometrial cells through gap junctions (GJs).

143 onsists of a sequence of angled graphene p-n junctions (GPNJs).

144 At the level of cell-to-cell junctions, HGF attenuates the linkage of stress fibers t

145 of hot electrons makes the nanoscale tunnel junctions highly reactive and facilitates strongly confi

146 Holliday junction (HJ) is a hallmark intermediate in DNA recombin

147 eurotransmitter release at the neuromuscular junction in Drosophila.

148 ncreases E-cadherin expression and cell-cell junction in epithelial cells.

149 ariant, and within the left temporo-parietal junction in patients with the semantic variant.

150 and sustains the remodelling of the adherens junction in response to mechanical forces.

151 nction) as well as in the gastro-oesophageal junction in the human gut.

152 These results reveal roles of gap junctions in a complex behavior at cellular resolution a

153 omyelinase is linked to degradation of tight junctions in endothelial cells in vitro, which is blocke

154 In addition, ROS disassembles adherens junctions in epithelial cells via posttranslational mech

155 We find that the triple junctions in graphene consist mostly of five-fold and se

156 study the structure and energetics of triple junctions in graphene using a multiscale modelling appro

157 nded to create patterned metal-semiconductor junctions in MoTe2 in a two-step lithographic synthesis.

158 ur results reveal a novel role for occluding-junctions in regulating niche-hematopoietic progenitor s

159 llular diapedesis by opening their cell-cell junctions in response to the presence of an adhering leu

160 iopoietins with Tie2 in cis and across EC-EC junctions in trans Except for the binding of the C-termi

161 ary diameter by pericytes and a role for gap junctions in vascular network interactions.

162 Our studies at the Drosophila neuromuscular junction indicate that many synaptic defects in unc-104-

163 thrombus within 3 cm of the sapheno-femoral junction, indication for full-dose anticoagulation thera

164 of oxidation and reduction reactions in the junctions, induced by the presence of O2 and H2 molecule

165 -/-) mice further suggested defective apical junction integrity in these mice.

166 blood-brain barrier model exemplifies tight-junction integrity.

167 ntractility is required to maintain adherens junction integrity.

168 er in the intestine via regulation of apical junction integrity.

169 in the granulosa cells diffuses through gap junctions into the oocyte, maintaining meiotic prophase

170 reveal that the flagella connector membrane junction is attached to the tips of extending microtubul

171 binding to single-stranded DNA (ssDNA)/dsDNA junctions is dependent on joint binding to the DNA bindi

172 reveal that the contact area of single ER-PM junctions is mainly oblong with the dimensions of approx

173 ; (2) demonstration that deltaN/N for CP-AFM junctions is remarkably small (</=2%) and that the large

174 about the CSR mechanism, and analysis of CSR junctions is useful in basic and clinical research studi

175 Par3, which is normally restricted to tight junctions, is sufficient to alter apical membrane identi

176 ulin-like domain (CLD) via an autoinhibitory junction (J).

177 desmoglein 2-positive contacts and increased junction length as revealed by immunofluorescence and el

178 ynaptic nerve terminals at the neuromuscular junction level, but not on the axonal tracts or myelin s

179 VE-cadherin at endothelial cell-cell junctions links the contractile acto-myosin cytoskeleton

180 et al. reveal that myosin-driven anisotropic junction loss and apical constriction are the main drive

181 on and thereby moderate inflammation-induced junction loss and associated endothelial monolayer perme

182 two-stage coalescence process of microscopic junctions made between the keratin of the stratum corneu

183 lycocalyx layer (EGL) and tight and adherens junction markers with plasma leakage.

184 l study, using mechanically controlled break junction measurements and density functional theory calc

185 metabolic substrates to neurons through gap junction-mediated astroglial networks.

186 nating microfluidics was conducted using a Y-junction microfluidic device, the design of which was op

187 ay inhibition via Y27632 disrupted cell-cell junction morphology, showing that cell contractility is

188 emperature sensor based on a Magnetic Tunnel Junction (MTJ) structure.

189 first time in Fe/AlOx/Fe3O4 magnetic tunnel junctions (MTJs).

190 k for exploration of mechanisms by which gap junction nexus stability modulates intercellular communi

191 uron (SMN) protein, leading to neuromuscular junction (NMJ) dysfunction and spinal motor neuron (MN)

192 4-MuSK receptor in muscles for neuromuscular junction (NMJ) formation.

193 The neuromuscular junction (NMJ) is a synapse formed between motoneurons a

194 d progressive weakening of the neuromuscular junction (NMJ).

195 We show that at larval neuromuscular junctions (NMJ), motor neuron expression of wild-type hu

196 neurons and their output, the neuromuscular junctions (NMJs), has been considered a key factor in th

197 occurs at embryonic Drosophila neuromuscular junctions (NMJs), where low-frequency Ca(2+) oscillation

198 cy are profound defects of the neuromuscular junctions (NMJs).

199 mitted from a scanning tunnelling microscope junction not only bears its intrinsic plasmonic signatur

200 Intrinsic ureteropelvic junction obstruction is the most common cause of congeni

201 nduced separation along the dermal-epidermal junction of ex vivo skin.

202 tion focuses attention to nt-pairings at the junction of R and U5, a poorly characterized structure u

203 ed (TR) dye was specifically attached in the junction of the dimerized origami to act as a Raman repo

204 culty of controlling spin waves in the input junction of the waveguides.

205 er epithelial tissues in which the adherence junctions of cells form a 2D manifold that is fluorescen

206 tion at the head cup bearing and the tapered junctions of orthopaedic hip implants are known to diffe

207 ney, ILDR1 is localized to tricellular tight junctions of the distal tubules.

208 e facilitating effect of intraglomerular gap junctions on interglomerular synchrony is through trigge

209 ither by configuring RNA-DNA hybrid four-way junctions or by template-directed synthesis with a singl

210 Pharmacological blockade of gap junctions or genetic ablation of connexin 36 (Cx36) subu

211 equences and junction structure (blunt-ended junctions or junctions with insertions or microhomology)

212 stem cells (hiPSCs) contained functional gap junctions partially contributed by Connexin 45 (CX45).

213 umor endothelium, activating TIE-2 and tight junction pathways and normalizing vessel structure and f

214 plasmonic nanorods with up to 10(11) tunnel junctions per square centimetre, which demonstrates hot-

215 perifusion insulin secretion assays, and gap junction permeability measurements.

216 is pivotal to further improve PCE of single junction perovskite solar cells (PVSCs) because of a bet

217 ous to a depleted metal-oxide-semiconducting junction, photo-generated charge collects in the potenti

218 the relative contributions of neuromuscular junction physiology and the motor program to the locomot

219 efects, but not the defects in neuromuscular junction physiology.

220 and C168Y) either form no morphological gap junction plaques or, if they do, produce little or no de

221 ale makes measurements of noise in molecular junctions possible.

222 light resulted in excitatory and inhibitory junction potentials, the electrical events underlying co

223 hottky catalyst based on metal-semiconductor junction principles is presented.

224 uires an intracellular scaffold called Tight Junction Protein 1b (Tjp1b).

225 ated small C terminus isoform, GJA1-20k (Gap Junction Protein Alpha 1- 20 kDa), which is required for

226 ssion of CLDN10, the gene encoding the tight junction protein Claudin-10, show enhanced paracellular

227 ial integrity indicated by loss of the tight junction protein claudin-3 was not observed during acute

228 d whether dysregulated expression of the gap junction protein connexin 43, which has been observed in

229 tations in GJB1, which codes for Cx32, a gap junction protein expressed by Schwann cells and oligoden

230 esses permeability-promoting claudin-2 tight-junction protein expression through an IL-10RA-dependent

231 t that stiff substrates change intercellular junction protein localization and degradation, which may

232 factors, the tetraspanin CD81 and the tight junction protein occludin (OCLN), explain, at least in p

233 ischemia induced rapid degradation of tight junction protein occludin in cerebromicrovessels.

234 ted tyrosine phosphorylation of the adherens junction protein vascular endothelial cadherin (VEC).

235 It uses some claudin tight junction proteins (eg, claudin-4) as receptors to form C

236 (matrilysis) as well as adherence and tight junction proteins for degradation.

237 d Cx43 are the most abundantly expressed gap junction proteins from each family.

238 membrane, where it associates with the tight-junction proteins Pals1/PATJ and E-cadherin.

239 affect the expression of tight and adherens junction proteins such as ZO-1, claudin, and JAM-A; howe

240 eQTL analysis against gene, exon, and splice-junction quantifications.

241 deposited by its chaperone, HJURP (Holliday junction recognition protein).

242 tensively studied in the context of adherens junction reinforcement to stabilize adhesive cell-cell c

243 cture consisting of an OB-fold and a holiday junction resolvase domain.

244 two domains, a third OB fold and a Holliday junction resolvase-like domain.

245 symmetric droplet splitting using a Y-shaped junction, resulting in two daughter droplets, one of whi

246 Amount and structural features of CSR junctions reveal valuable information about the CSR mech

247 sal involvement of the right temporoparietal junction (rTPJ) in updating probabilistic beliefs and we

248 vide evidence that the right temporoparietal junction (rTPJ) is causally involved in this process.

249 apoptosis, immune evasion, and loss of cell junctions seen in H. pylori-infected host cells.

250 CSReport identifies junction segment breakpoints on reference sequences and

251 generated sg mRNAs with variant leader-body junction sequences.

252 mas of the oesophagus and gastro-oesophageal junction (Siewert types 1 and 2).

253 lipid metabolism, oxidative stress and cell junction signaling in testes.

254 Our simulations show that the asperity junction size dictates the debris volume, revealing the

255 The junction size is controlled with a dual-gate device cons

256 fully recapitulate that of epithelial tight junction strands, this is the first direct demonstration

257 gment breakpoints on reference sequences and junction structure (blunt-ended junctions or junctions w

258 how a CMOS-compatible, nanostructured, thin junction structure can make use of tailored light trappi

259 pling in a new perpendicular magnetic tunnel junction system with a GdOx tunnel barrier, where a larg

260 on using the mechanically controllable break junction technique.

261 In contrast to the splicing junctions that can be efficiently detected from spliced

262 Desmosomes are macromolecular cell-cell junctions that provide adhesive strength in epithelial t

263 equences from our HTS-based protocol for CSR junctions, thereby facilitating and accelerating their s

264 suggests that RASSF4 controls SOCE and ER-PM junctions through ARF6-dependent regulation of PM PI(4,5

265 ered cytoskeletal structure, increased tight junction (TJ) formation and reduced barrier permeability

266 ance (TEER) measurements without other tight-junction (TJ) formation parameters.

267 Tight junction (TJ) proteins are known to be involved in proli

268 family of proteins is integral to the tight junction (TJ), the apical cell-cell adhesion and a key r

269 Delivery occurs adjacent to tight junctions (TJ), suggesting that it recognizes a receptor

270 paracellular passage regulated through tight junctions (TJ).

271 Tight junctions (TJs) form a barrier on the apical side of nei

272 Endothelial cells lining SC elaborate tight junctions (TJs), down-regulation of which may widen para

273 cted by FGFR2 signaling, possibly offering a junction to exploit therapeutically.Significance: Bindin

274 ecific kinesin facilitates attachment of the junction to the microtubules in the mature flagellum.

275 in complexes transduce force fluctuations at junctions to activate signals that reinforce stressed in

276 Epithelial cells connect via cell-cell junctions to form sheets of cells with separate cellular

277 oarse-grained simulations of a wide range of junction topologies indicate that differences in sterics

278 nerous decisions engage the temporo-parietal junction (TPJ) in the experimental more than in the cont

279 EGFRs) that resides at endothelial cell-cell junctions transduces signals important for flow-dependen

280 compared with the recently proposed bipolar junction transistor (BJT) transducer.

281 Bipolar junction transistors are at the frontiers of modern elec

282 We calculate single-molecule junction transmission and the complex band structure of

283 al carcinoma, including the gastroesophageal junction tumors (Siewert I), were randomized between ope

284 expression of connexin43, a major known gap junction unit in vascular cells.

285 triggered phenothiazine (PTZ-) based radical junction using the mechanically controllable break junct

286 but that the frequency of intermitochondrial junctions was reduced.

287 the RCM reaction to install the C18-C19 ring junction, was successful in assembling the macrolactone.

288 At the neuromuscular junction, we showed mEPP amplitudes and frequency requir

289 es bearing a hydroxymethyl group at the ring junction were synthesized from a readily available l-sor

290 or localization of STIM1 and E-Syts at ER-PM junctions, were reduced in RASSF4-knockdown cells.

291 olecular and bacterial movement across tight junctions, while increased intestinal permeability accom

292 ge in the exact flow split location in the T-junction with flow ratio.

293 the linkage of stress fibers to cell-to-cell junctions with concomitant decrease in intercellular str

294 junction structure (blunt-ended junctions or junctions with insertions or microhomology).

295 Junctions with nonradical units rectify currents via the

296 Using this platform, we studied gold junctions with prototypical molecules (Au-biphenyl-4,4'-

297 HOMO) with a rectification ratio R = 99, but junctions with radical units have a new accessible state

298 followed by the identification of breakpoint junctions within a population, which typically arise by

299 ned with the apical actin cable and adherens-junctions within chick and mouse neuroepithelial cells.

300 ive and specific enrichment for poly(A) site junctions without the need for complex sample preparatio