ライフサイエンスコーパス: junctional complex

1 capacity to do so if targeted to the apical junctional complex.

2 ed on the synaptic membranes or the synaptic junctional complex.

3 es of cell-cell contact, adjacent to the gap junctional complex.

4 g the composition and function of the apical-junctional complex.

5 ons with other components of the endothelial junctional complex.

6 -spectrin is crucial to the stability of the junctional complex.

7 in zonula occludens 1 protein from the tight junctional complex.

8 to organize these proteins within the apical junctional complex.

9 as not previously been reported as part of a junctional complex.

10 coded protein is assembled into the synaptic junctional complex.

11 actin and alpha-actinin into a host-parasite junctional complex.

12 ibutes to the maturation and assembly of the junctional complex.

13 VE-cadherin demonstrated organization of the junctional complex.

14 58 is essential for flow sensing through the junctional complex.

15 PAMR is essential for assembly of the apical junctional complex.

16 the assembly but not the maintenance of the junctional complex.

17 tin-spectrin junctions are considered at the junctional complex.

18 ose proximity to ZO-1, a marker of the tight junctional complex.

19 or vesicle docking or fusion adjacent to the junctional complex.

20 ractility of the cortical actin at the tight junctional complex.

21 ranes by stabilizing the spectrin-actin-4.1R junctional complex.

22 lipid bilayer by ankyrin and by actin-based junctional complexes.

23 ement membrane and had apical microvilli and junctional complexes.

24 etworks to each other as well as to the cell junctional complexes.

25 atenin were colocalized at the intercellular junctional complexes.

26 to do so appears to affect the integrity of junctional complexes.

27 isease, may be caused by defective epidermal junctional complexes.

28 Electron microscopy demonstrated normal junctional complexes.

29 d sequester the protein in the cytoplasm and junctional complexes.

30 ent of podocyte foot processes with abnormal junctional complexes.

31 minant negative to disrupt actin dynamics at junctional complexes.

32 dissociation of claudin-5 and VE-cadherin at junctional complexes.

33 eta-subunits at spectrin-actin junctions, or junctional complexes.

34 he timely reestablishment of p120-containing junctional complexes.

35 nction is regulated by the epithelial apical junctional complex (AJC) consisting of the tight junctio

36 Reorganization of the apical junctional complex (AJC) in response to TNF-alpha was vi

37 The epithelial apical junctional complex (AJC) is an important regulator of ce

38 Apical junctional complex (AJC) plays a vital role in regulatio

39 Disassembly of the epithelial apical junctional complex (AJC), composed of the tight junction

40 cells depends on the formation of the apical junctional complex (AJC), which is composed of the tight

41 on and colocalizes with E-cadherin to apical junctional complexes (AJC) in differentiated polarized C

42 Alterations in apical junctional complexes (AJCs) have been reported in geneti

43 when NPCs normally acquire organized apical junctional complexes (AJCs) in the zebrafish hindbrain.

44 formation revealed that disruption of apical junctional complexes (AJCs) was responsible for PH in Ne

45 the restricted distribution of proteins and junctional complexes along an apical-basal axis.

46 etaV was invariably detected near the apical junctional complex and above the cuticular plate, a dens

47 d at the developing thalamocortical synaptic junctional complex and demarcates these synaptic junctio

48 tients with Crohn's disease influence apical junctional complex and epithelial barrier function.

49 binds to components of the cadherin-catenin junctional complex and has been implicated in cell-cell

50 the band 3 population to the spectrin/actin junctional complex and its formation of a new bridge wit

51 lls but also generates changes in the apical junctional complex and loss of epithelial barrier functi

52 is involved in CVB-induced disruption of the junctional complex and rearrangements of the actin cytos

53 meric exocyst complex is associated with the junctional complex and recycling endosomes and is propos

54 hich controls the organization of the apical junctional complex and the actin cytoskeleton in mammary

55 ernative protein-mediated bridge between the junctional complex and the cytoplasmic domain of band 3

56 those known to be part of the slit diaphragm junctional complex and those previously described in the

57 ed cells show increased N-cadherin levels at junctional complexes and cannot resolve cell-cell juncti

58 such as E-cadherin enrichment in epithelial junctional complexes and CD45 exclusion from the signali

59 ating via the PCP pathway, and in regulating junctional complexes and cell cohesion.

60 revealed that VASP localizes to endothelial junctional complexes and colocalizes with ZO-1, occludin

61 ects in Sertoli cell polarity and testicular junctional complexes and decreased activation of the MAP

62 ructural level, the superficial cells formed junctional complexes and had an asymmetric unit membrane

63 th of these mutants are impaired in altering junctional complexes and increasing paracellular permeab

64 ive cell polarity, resulting in mislocalized junctional complexes and loss of adhesion to extracellul

65 eral cell-cell contact underneath the apical-junctional complexes and requires activation of the Rho-

66 -cadherin and beta-catenin labeling from the junctional complexes and the concomitant appearance of i

67 oteins essential to maintain normal cellular junctional complexes and tissue homeostasis.

68 is protein to be a component of various cell junctional complexes and to be associated with the cytos

69 bility of H. pylori to compromise epithelial junctional complexes and to induce proinflammatory cytok

70 geometric graph, with nodes corresponding to junctional complexes and with edges corresponding to spe

71 Multiple signaling proteins regulate the junctional complex, and several (including G proteins) h

72 logue, aardvark, which is a component of the junctional complex, and, independently, is required for

73 y to regulate the integrity of intercellular-junctional complexes, and cell shape and volume in respo

74 elium exhibited apical vacuoles, microvilli, junctional complexes, and linear basement membranes.

75 ction permeability and alterations in apical-junctional complexes are also associated with an increas

76 Previous studies have shown that these two junctional complexes are important for keratinocyte cell

77 Epithelial apical junctional complexes are multiprotein subunits that prom

78 he PDZ domains, which recruit the LRR to the junctional complex, are dispensable for overall epitheli

79 eoglycan with HS chains that is critical for junctional complex assembly and regulating the flow resp

80 pressed in MDCK cells are localized near the junctional complex, associate with at least one TJ prote

81 n contributes to the loss of function of the junctional complex associated with sublethal injury.

82 The same molecules also comprise the junctional complexes at the BTB.

83 ty did not reflect lateral diffusion through junctional complexes because a low-density lipoprotein r

84 ites important for impulse transmission: the junctional complex between cardiac myocytes, the heart c

85 process despite the similar structure of the junctional complex between pial and parenchymal vessels

86 th Z disks, whereas alpha-synemin stabilizes junctional complexes between cardiomyocytes.

87 oplasmic opacity, as well as aggregations of junctional complexes between cells.

88 -1 and stabilin-1 and was facilitated by the junctional complexes between HSECs.

89 e, highlighting differences in redundancy in junctional complexes between organs and species.

90 Unique intercellular junctional complexes between the central nervous system

91 ular development, IQGAP1 is expressed in the junctional complexes between the earliest identifiable p

92 phology consisting of ill-defined epithelial junctional complexes but without expression of mesenchym

93 h cytokines induce disassembly of the apical junctional complex by promoting differential endocytosis

94 f transporters and specialized intercellular junctional complex components.

95 skeleton consists of hexagonal lattices with junctional complexes containing F-actin protofilaments o

96 y uniform two-dimensional hexagonal array of junctional complexes cross-linked by spectrin tetramers.

97 ssociated with ischaemia and reperfusion the junctional complex 'deforms' into the permeability trans

98 Coated pits, junctional complexes, desmosomes, and basement membranes

99 luding cell differentiation, the presence of junctional complexes/desmosomes and microvilli, and the

100 been hypothesized to link the spectrin-actin junctional complex directly to the cytoplasmic domain of

101 ites link and stabilize into mature synaptic junctional complexes distributed with precise topographi

102 structure and function of epithelial apical junctional complexes, emphasizing how regulation of the

103 proteins involved in the pathway of the PAR junctional complex, especially aPKC, and both aPKC and B

104 scular endothelial-cadherin from endothelial junctional complexes fails to redistribute ECRTP/DEP-1.

105 eptor signaling to the coordinate control of junctional complex formation and cell-cell interactions

106 ) localization of each Frizzled at cell-cell junctional complexes formed by mouse Celsr1, a likely in

107 sts of spectrin tetramers connected at actin junctional complexes, forming a two-dimensional (2D) six

108 revealed that Notch signaling induces apical junctional complex genes that regulate cell adhesion and

109 ect the partitioning defective protein (PAR) junctional complex identified by the rescue experiment w

110 n plays a role in the assembly of the apical junctional complex in epithelia.

111 non-polarized epithelial cells and with the junctional complex in polarized IECs and human intestine

112 rcellular junction referred to as the apical junctional complex in regulating small intestinal epithe

113 gether with a three-dimensional model of the junctional complex in the erythrocyte membrane, to explo

114 fficking, which were present near the apical junctional complex in the hair cells of mammalian ancest

115 rs and octamers seen between virtually every junctional complex in the network.

116 ceramide and aPKC regulate the formation of junctional complexes in epithelial cells.

117 odocytes, MAGI-2/S-SCAM is first detected in junctional complexes in podocytes after their migration

118 Nok localizes to the vicinity of junctional complexes in retinal neuroepithelium and in t

119 he spectrin-actin junctions, also called the junctional complex, in the erythrocyte membrane.

120 ctivity associated with markers of the tight junctional complex, including zonula occludens 1 (ZO-1)

121 g imaginal discs are organized into distinct junctional complexes, including separate distributions f

122 e actin-binding proteins of the erythrocyte "junctional complex." Individually, they exert modest eff

123 hypothesis that the loss of integrity of the junctional complex induced by ATP depletion is related t

124 The epithelial apical junctional complex is important in determining epithelia

125 thelial flow mechanotransduction through the junctional complex is mediated by a specific pool of VE-

126 tour length of spectrin filaments connecting junctional complexes is 46 +/- 15 nm, indicating that th

127 ch is associated with the spectrin-actin-4.1 junctional complex, is associated with an abnormal membr

128 adherens junction and to dysfunction of the junctional complex, it is proposed that the increase in

129 vary glands due to disruptions of epithelial junctional complexes, likely secondary to elevated activ

130 result of alterations in the organization of junctional complex molecules.

131 at a number of levels, including epithelial junctional complexes, mucus production, and mucosa-deriv

132 he neural crest cell tail during retraction (junctional complexes not completely downregulated), or t

133 ontributes to epicardial EMT and implicate a junctional complex of beta-catenin and Numb in the regul

134 nd both exhibit a close association with the junctional complex of polarized epithelia.

135 e both structure and signaling at the apical junctional complex of polarized epithelial cells.

136 or the stable incorporation of ZO-1 into the junctional complex of polarized MDCK cells.

137 ncluding ankyrin, adducin, spectrin, and the junctional complex of the skeleton.

138 rs, cell adhesion molecules that localize to junctional complexes of epithelial cells and other cell

139 ween the podocyte slit diaphragm and typical junctional complexes of other epithelial cells.

140 rs of heterodimers attached at their ends to junctional complexes of several proteins.

141 There are indications that the junctional complex, or components of it, may also mediat

142 secreted bacterial protease disrupts apical-junctional complexes, paving the way for H. pylori to ac

143 g enamel matrix proteins, MMP20 also cleaves junctional complexes present on ameloblasts to foster th

144 lls stained positive for pancytokeratin, the junctional complex protein ZO-1, collagen type IV, as we

145 Additionally, apical junctional complex proteins are targeted by pathogens th

146 In contrast, genes encoding interepithelial junctional complex proteins defined alterations in tight

147 ymal vessels) by examining the expression of junctional complex proteins in murine brain infected wit

148 cker, doxycycline reduced the degradation of junctional complex proteins in parenchymal vessels.

149 s is accompanied by redistribution of apical junctional complex proteins to form intercellular barrie

150 ammatory cytokines and endocytosis of apical junctional complex proteins to the epithelial barrier de

151 is near the 4.1/actin-binding region at the junctional complex providing new evidence that this 13-a

152 nents of the cardiac area composita, a mixed junctional complex responsible for electromechanical cou

153 anes from neighboring cells rapidly assemble junctional complexes, self-contacting membranes curiousl

154 Promotion of cytoskeletal junctional complex stability requires an erythroid diffe

155 lateral cell perimeters in the proximity of junctional complexes, suggesting a loss of normal cell c

156 ell plasma membrane domains are separated by junctional complexes supported by actin.

157 gs suggest that they form a mechanosensitive junctional complex that discriminates between different

158 -p55-glycophorin C linkage exists at the RBC junctional complex that involves interactions between sp

159 The intercalated disc contains different junctional complexes that enable the myocardium to funct

160 matin is a major component of red blood cell junctional complexes that link the spectrin-actin cytosk

161 One of the junctional complexes, the zonula adherens or adherens ju

162 ib markedly reduces cell-cell apposition and junctional complexes, thus reducing the proximity typica

163 w model whereby dematin and adducin link the junctional complex to human erythrocyte plasma membrane.

164 that connects the spectrin/actin/protein 4.1 junctional complex to the bilayer.

165 the paracellular space and anchoring of the junctional complex to the cytoskeleton.

166 viding a rationale for the attachment of the junctional complex to the lipid bilayer.

167 dematin-membrane interaction could link the junctional complex to the plasma membrane in erythroid c

168 ent their centrosomes toward these localized junctional complexes to carry out asymmetric divisions.

169 transient or stable breakdown of epithelial junctional complexes to permit programmed migration, inv

170 Furthermore, components of cell-cell junctional complexes undergo profound rearrangements: E-

171 i) a fraction attached to the spectrin-actin junctional complex via adducin, and (iii) a freely diffu

172 Specific expression at the junctional complex was confirmed by immuno-EM.

173 This newly identified junctional complex was tissue specific but not unique to

174 a protein involved in spermatid-Sertoli cell junctional complexes, was used.

175 By contrast with core components of the junctional complex, we find that merlin is required spec

176 Although junctional complexes were evident, junctions were abnorm

177 The junctional complexes were identified with immunofluoresc

178 tor islet cell cultures were devoid of tight junctional complexes, which may facilitate channel forma

179 dies revealed the presence of sarcomeres and junctional complexes, while immunofluorescence confirmed

180 vesicles that accumulate, interact, and form junctional complexes with each other and the axolemma at

181 pared myocardium after infarction by forming junctional complexes with resident myocytes.

182 er, enter the next cell by traveling through junctional complexes without being intercepted by a neut