ライフサイエンスコーパス: juvenile polyp

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1 ed somatic PTEN alterations in the stroma of juvenile polyps.

2 because of the shared features of intestinal juvenile polyps.

3 ed to 10q22-24 in both familial and sporadic juvenile polyps.

4 mical staining occurred rarely in dysplastic juvenile polyps (2 of 24, 8%).

5 gene were demonstrated in 50% of dysplastic juvenile polyps (3 of 6) but not in any of 16 juvenile p

6 deletions at 10q22 were detected in 39 of 47 juvenile polyps (83%) from 16 unrelated patients with ei

7 ers develop upper and lower gastrointestinal juvenile polyps and are at increased risk for gastrointe

8 sis that the genetic defect in both sporadic juvenile polyps and hereditary juvenile polyposis involv

9 tal epithelium was lost in 79% of dysplastic juvenile polyps and in 8% of nondysplastic juvenile poly

10 Affected patients commonly develop juvenile polyps, and show an elevated risk of developing

11 s is not a prerequisite for the formation of juvenile polyps, and that colorectal juvenile polyps in

12 patients with either hereditary or sporadic juvenile polyps, and the minimum overlap localized juven

13 y acts as a "gatekeeper" tumor suppressor in juvenile polyps, and there is no need to invoke a "lands

14 Juvenile polyps are characterized by an abundant lamina

15 Juvenile polyps are present in a number of Mendelian dis

16 Juvenile polyps are regarded as hamartomatous polyps and

17 Dysplasia occurred in 31% of syndromic juvenile polyps but not in sporadic juvenile polyps (P <

18 ith juvenile polyps syndrome and 34 sporadic juvenile polyps for epithelial dysplasia and genetic cha

19 ormal DNA with tumor DNA from a series of 47 juvenile polyps from 16 patients using polymerase chain

20 Both sporadic and syndromic juvenile polyps had K-ras mutations (14%) and there was

21 tion of juvenile polyps, and that colorectal juvenile polyps in CS are bona fide neoplastic precursor

22 specific PTEN deletion to cause formation of juvenile polyps in the colorectum without stromal PTEN l

23 Recent data show juvenile polyps may recur in approximately 45% of childr

24 as and carcinomas of the colonic epithelium, juvenile polyps originate in the lamina propria.

25 c juvenile polyps and in 8% of nondysplastic juvenile polyps (P < 0.000001).

26 yndromic juvenile polyps but not in sporadic juvenile polyps (P < 0.0001).

27 play a role in neoplastic transformation of juvenile polyps, predominantly in juvenile polyposis syn

28 characteristic histopathological features of juvenile polyps seen in patients with CS, including stro

29 tal juvenile polyposis from 12 patients with juvenile polyps syndrome and 34 sporadic juvenile polyps

30 cted by deletion mutation in the majority of juvenile polyps was mapped.

31 uvenile polyps (3 of 6) but not in any of 16 juvenile polyps without dysplasia (P = 0.01).

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