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1 cytoplasmic inclusions appear as a distinct juxtanuclear accumulation at the centrosome and this req
2 y, Anxa6 knockdown also abrogated PE-induced juxtanuclear accumulation of secretory granules (SG) con
3 ts led to increased superoxide anion levels, juxtanuclear accumulation of ubiquitin- and p62/SQSTM1-p
4 e that undergoes a rapid condensation into a juxtanuclear aggregate during chemokine-induced polariza
6 roteasome activity elicited the formation of juxtanuclear aggregates with characteristics of aggresom
7 , trafficking of a folding mutant that forms juxtanuclear aggregates, EGFP/SP-C(C122/186G), was not c
8 ese severe defects developed gradually after juxtanuclear aggresome formation and were not associated
9 /-) cells with prosaposin localized to large juxtanuclear aggresome-like inclusions, which is indicat
10 racellular degradative capacity is exceeded, juxtanuclear aggresomes are formed to sequester misfolde
12 nd caused redistribution of the receptors to juxtanuclear aggresomes, significantly more so for TPbet
13 ubiquitinated (K48/K63-linked) proteins into juxtanuclear aggresomes, without affecting 20S proteasom
14 of microtubules eliminated the formation of juxtanuclear and intranuclear inclusion bodies by HtEx1.
15 osomes and mitochondria were enriched in the juxtanuclear area and co-aggregate into a compact inclus
16 n also causes clustering of lysosomes in the juxtanuclear area of the cell, but the mechanisms respon
19 ogenous SSBP2 protein and sequesters it into juxtanuclear bodies in adenovirally transformed human em
20 microtubules to retain the integrity of the juxtanuclear bodies suggests them to be E1B55K containin
22 en fluorescent protein, hLnk is found at the juxtanuclear compartment and also appears to be localize
23 s, while the 75-kDa protein localized to the juxtanuclear compartment and was packaged into virion pa
24 betaII (PKC betaII) translocated to a novel juxtanuclear compartment as observed in several cell typ
25 n the plasma membrane, but not in a distinct juxtanuclear compartment in which NHE3 is predominantly
27 zed together with other virion proteins in a juxtanuclear compartment termed the assembly compartment
28 rane, while E3-7.7K localized primarily to a juxtanuclear compartment that could not be identified.
30 ation, and ErbB2 was observed to move into a juxtanuclear compartment where it colocalized with PKC-a
31 uitinated misfolded proteins accumulate in a juxtanuclear compartment where proteasomes are concentra
33 umulation of internalized cargo in a compact juxtanuclear compartment, Rabenosyn-5-RNAi caused its re
38 egress from the nucleus and associate with a juxtanuclear cytoplasmic assembly compartment, where vir
41 ly causing the observed retention of BST2 in juxtanuclear endosomes and stimulating its degradation i
43 g microtubule depolymerization, the central, juxtanuclear Golgi apparatus scatters to multiple periph
46 d dynein for its retrograde transport to the juxtanuclear Golgi complex and that STB increases MT ass
49 lgi enzymes gradually redistributed from the juxtanuclear Golgi or Golgi ministacks to the ER in cell
52 duce two distinct types of aggregates: large juxtanuclear inclusion bodies and small punctate aggrega
53 S reactivity of the fractions show that the juxtanuclear inclusion bodies are filled with amyloid-li
56 d cells frequently leads to the formation of juxtanuclear inclusions that have been termed 'aggresome
57 sequently found to be enclosed within large, juxtanuclear, LAMP-1-positive vacuoles called Francisell
58 er, a large fraction of Hook3 maintained its juxtanuclear localization after Brefeldin A treatment, i
60 Fragmented Golgi membranes maintained their juxtanuclear localization, cisternal organization and ar
61 ding to IEV in size and shape, moving from a juxtanuclear location to the periphery of the cell, wher
62 o one in which filaments are aggregated in a juxtanuclear location, opposite to the direction of cell
63 lpha1, or N-cadherin, generate intracellular juxtanuclear membrane tubules when expressed in cells.
66 y: peripheral lysosomes are less acidic than juxtanuclear ones despite their comparable buffering cap
67 lized SV5 HN in vesicle-like structures in a juxtanuclear pattern coincident with the localization of
69 G132-treated quiescent cells displayed fewer juxtanuclear protein aggregates, less apoptosis, and hig
71 s localize to one of these compartments, the juxtanuclear quality control compartment (JUNQ), and int
72 vented the translocation of PKCbetaII to the juxtanuclear region but not to the plasma membrane, thus
73 dosomes, which were less concentrated at the juxtanuclear region in mutant cells than in control fibr
74 at the deposition of the protofibrils in the juxtanuclear region is important in fibril formation.
76 ular membrane compartment emanating from the juxtanuclear region of cells, which resembled the compar
77 olgi apparatus and recycling endosome in the juxtanuclear region of resting peritoneal macrophages.
80 y demonstrated that virion movement from the juxtanuclear region to the periphery was saltatory with
81 es a dramatic redistribution of CAL from the juxtanuclear region to the plasma membrane where the two
83 C10 directs the trafficking of CFTR from the juxtanuclear region to the secretory pathway toward the
84 ER stress conditions, the QCVs converge in a juxtanuclear region, at the ERQC, as previously reported
86 AGS3 and AGS3-GFP from the cell cortex to a juxtanuclear region, where it co-localized with markers
94 KCbetaI translocates to a recently described juxtanuclear site of localization for PKCalpha and PKCbe
96 Immunofluorescent staining reveals striking juxtanuclear staining characteristic of the Golgi appara
99 The morphology of the SDYQRL-TR-containing juxtanuclear structures is different from the recycling
102 both necessary and sufficient for preventing juxtanuclear translocation of PKC betaII in response to
108 ells, the SDYQRL-TR construct accumulated in juxtanuclear tubules and vesicles that are in the vicini
109 GF receptors from peripheral compartments to juxtanuclear vesicles, and their subsequent degradation.
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