ライフサイエンスコーパス: kDa

1 analysis of middle-range peptides (i.e., 3.0 kDa < Mw < 10 kDa), aptly termed middle-down proteomics.

2 ely small peptides (i.e., 0.7 kDa < Mw < 3.0 kDa) or small to medium sized intact proteins (i.e., 10

3 Here, we show that an approximately 1,000-kDa complex called the late boundary complex (LBC), whic

4 ed uniform BCPs with molar masses up to 12.1 kDa on approximately 1 g scale.

5 This included 323 proteoforms for the 14.1 kDa ASV alone.

6 m surface waters, wastewater effluent, and 1 kDa size fractions were adsorbed by GAC and characterize

7 ractionation-ICPMS analyses to sizes > ca. 1 kDa.

8 que in its permeability to molecules up to 1 kDa in size and its release of ATP.

9 ll to medium sized intact proteins (i.e., 10 kDa < Mw < 30 kDa), respectively, termed bottom-up and t

10 racers (<3 kDa), but not larger tracers (>10 kDa).

11 ddle-range peptides (i.e., 3.0 kDa < Mw < 10 kDa), aptly termed middle-down proteomics.

12 cebus lehilahytsara contain a predominant 10 kDa protein, expressed in both species by some, but not

13 MDM) compared to culture filtrate protein 10 kDa (CFP10) and antigen 85A.

14 P10 is a 10-kDa auxiliary protein produced in the very late phase of

15 Lung-specific IL-13 transgenic (Club cell 10-kDa protein [CC10]-IL-13 Tg) mice and wild-type litterma

16 actioned, and the effective fraction (30-100 kDa) was analyzed by liquid chromatography-mass spectrom

17 haracterize a hypothetical approximately 100 kDa single-chain protein, YonO, encoded by the SPbeta pr

18 wever, diffusion of antibody molecules (>100 kDa) is slow and often results in uneven labeling with v

19 strates have a molecular mass from 50 to 100 kDa and a slightly acidic pI (5.4-6.8).

20 Here we structurally characterize the >100-kDa ternary complex by NMR and negative stain EM and sho

21 kb M25 mRNA directing the synthesis of a 105 kDa M25 protein, and confirmed that a late 3.1 kb mRNA e

22 howed complete loss of full-length NEK9 (107 kDa).

23 TCPs of about 11 kDa are present in acute wound fluids as well as in fibr

24 hil elastase cleaves thrombin, generating 11-kDa thrombin-derived C-terminal peptides (TCPs), which b

25 -peptide N-acetylglucosaminyltransferase 110 kDa subunit (OGT1) and kinesin heavy chain isoform 5A an

26 report that the PML-NB protein Speckled 110 kDa (Sp110) is SUMO1-modified and undergoes a deSUMOylat

27 creased, whereas levels of a TTX-soluble 115 kDa VE-cadherin species were increased in old compared t

28 89 +/- 0.04, 3.20 +/- 0.03 and 3.50 +/- 0.12 kDa for DOM-associated Fe in the three samples (+/-95% C

29 ugh the recruitment and inhibition of the 12-kDa cis-trans proline isomerase FK506-binding protein (F

30 Thioredoxin (TRX)-1, a ubiquitous 12-kDa protein, exerts antioxidant and anti-inflammatory ef

31 ane and forms a complex of approximately 120 kDa.

32 acid, and stearic acid at C78 of the 17.125 kDa ASV.

33 firmed that a late 3.1 kb mRNA encodes a 130 kDa M25 tegument protein.

34 A 134-kDa protein complex LptB2FG is unique among ATP-binding

35 hat because of the scaffold's small size (14 kDa), its pharmacokinetics may be suitable for labeling

36 A 140 kDa VE-cadherin species was present on the cell surface

37 inhibition (saracatinib) increased: (i) 140 kDa VE-cadherin in the TTX-insoluble fraction, (ii) VE-c

38 Levels of the 140 kDa VE-cadherin were decreased, whereas levels of a TTX-

39 Dialysis experiments show that, for a 15 kDa polyelectrolyte, a 50 kDa dialysis membrane is not s

40 n enriched in astrocytes at approximately 15 kDa (PEA15), and its mRNA are regulated by PS1/gamma-sec

41 d nanoparticles (AuNPs) were wrapped with 15 kDa poly(allylamine hydrochloride) (PAH), and three puri

42 apparent molecular mass of approximately 150 kDa on SDS-PAGE and did not contain Gbeta5 Mass spectrom

43 ane antigen (PSMA) huJ591 antibody (IgG; 150 kDa) and its minibody (Mb; 80 kDa) format were functiona

44 timate a threshold for detection that is 150 kDa in ice and 300 kDa in 100 nm thick samples of dense

45 a glycoprotein with a molecular mass of 150 kDa.

46 molecular weights ranging from 560 Da to 150 kDa.

47 other proteins to be present within the 150-kDa complex in the amount close to stoichiometric with R

48 KEY POINTS: Leptin, is a 16 kDa pleiotropic peptide not only primarily secreted by a

49 ABSTRACT: Leptin, is a 16 kDa pleiotropic peptide not only primary secreted by adi

50 ix patient sera a pair of bands of 10 and 16 kDa, and in nine a 16-kDa band.

51 lated phospho-protein of molecular weight 16 kDa) is one of several small acid-soluble proteins highl

52 of bands of 10 and 16 kDa, and in nine a 16-kDa band.

53 tein kinase B (PKB) and Akt substrate of 160 kDa (AS160), (ii) via an AS160-independent pathway from

54 rotein and paralogue of Akt substrate of 160 kDa (AS160), has been implicated in both insulin- and 5-

55 rotein phosphatase 1 inhibitor protein of 17 kDa) phosphorylations.

56 We show that PDZD11 (17 kDa) is expressed in epithelial and endothelial cells, w

57 ning, we identified an accessory protein, 17 kDa membrane-associated protein (MAP17), that increased

58 -specific PCR targets (ompA,gltA, and the 17-kDa protein gene).

59 lecular mass distribution between 10 and 170 kDa.

60 , where their folding is surveyed by the 170-kDa UDP-glucose:glycoprotein glucosyltransferase (UGGT).

61 most complete sequence coverage for this 173-kDa protein.

62 Two crystal structures of Japanin, an 18 kDa immune-modulatory lipocalin from the Brown Ear Tick

63 dy was to test for an association between 18 kDa translocator protein brain positron emission tomogra

64 otracers that target translocator protein 18 kDa (TSPO) has become a popular approach to assess putat

65 tudies targeting the translocator protein 18 kDa (TSPO) have been limited by high nonspecific binding

66 In AD, the translocator protein 18 kDa (TSPO) is overexpressed in the activated microglia t

67 ose tissue (BAT) and translocator protein 18 kDa (TSPO) via a combination of disulfiram, an FDA appro

68 To measure translocator protein 18 kDa (TSPO), a marker of activated glial cell response, i

69 ng radiolabeled ligands selective for the 18 kDa translocator protein (TSPO) has become the most wide

70 The 18 kDa translocator protein, TSPO, is a cholesterol-binding

71 expression of translocator protein (TSPO) 18 kDa, thereby making the TSPO expression a marker for neu

72 For PET imaging of 18-kDa translocator protein (TSPO), a biomarker of neuroinf

73 Brain levels of 18-kDa translocator protein (TSPO), a marker of microglial

74 -generation tracer for PET imaging of the 18-kDa translocator protein (TSPO), a marker of neuroinflam

75 racer developed for SPECT and targets the 18-kDa translocator protein (TSPO).

76 companied by a rapid up-regulation of the 18-kDa translocator protein (TSPO).

77 tamide (DPA-714) is a radioligand for the 18-kDa translocator protein.

78 activation can be detected in vivo using 18-kDa translocator protein (TSPO)-binding radioligands and

79 dies show that in mature tissues TMV 126/183-kDa-interacting Aux/IAAs predominantly express and accum

80 rythrocytic stage vaccine candidates, the 19 kDa fragment of the P. vivax Merozoite Surface Protein 1

81 enes including BNIP3 (BCL2/adenovirus E1B 19-kDa protein-interacting protein 3) and GLUT1 (glucose tr

82 e mitophagy regulator BCL2/adenovirus E1B 19-kDa-interacting protein 3-like (BNIP3L, best known as NI

83 d can block entry mediated by the primed (19-kDa) form of GP without impeding binding of the C-loop o

84 d that a genetic fusion of the C-terminal 19-kDa fragment of merozoite surface protein 1 (MSP119) to

85 evidenced that low molecular weight (50-190 kDa) chitosan can be used to mitigate the formation of a

86 Here we tested the effect of RA101295, a 2-kDa macrocyclic peptide inhibitor of C5 cleavage, using

87 , GJA1-20k (Gap Junction Protein Alpha 1- 20 kDa), which is required for full-length Cx43 trafficking

88 3 forward trafficking and that Cx43 has a 20 kDa internally translated small C terminus isoform, GJA1

89 ogous, C-terminal domain of approximately 20 kDa and at least one key residue difference in the conse

90 ased the proportion of low MW fractions (<20 kDa) from 4.22% to 39.4%, which are more biodegradable.

91 dicate a specific interaction between the 20 kDa amino terminus and 65 kDa carboxy terminus, after pr

92 , (H)CACONH, and (H)CBCANH spectra of the 20 kDa bacteriophage tail-tube protein gp17.1 in a total ti

93 Thus, the 20 kDa fragment functions to provide stability to the C-ter

94 ntraction requires phosphorylation of the 20 kDa light chain of myosin, which activates crossbridge c

95 ephosphorylation of eNOS(pThr497) and the 20 kDa myosin II light chains.

96 proteolytic conditions in absence of the 20 kDa N-terminus.

97 ereas a truncated form lacking the 17- to 20-kDa N-terminal domain is completely inactive under ident

98 ative gels in a complex of approximately 200 kDa that also contained beta-tubulin.

99 ing its target antigen, an extracellular 200 kDa carbohydrate, in saline swabs.

100 amount of high molar mass material (M 200 kDa).

101 IP200 (FAK family-interacting protein of 200 kDa), an Atg in autophagy induction, we examined FIP200

102 The 200 kDa complex has been recalcitrant to crystallization, so

103 ers of magnitude, from roughly 10 MDa to 200 kDa under typical HPT fracturing conditions.

104 onding molecular weight of approximately 211 kDa.

105 polymers with molecular weights (Mn) of 9-22 kDa.

106 Scabin was purified to homogeneity as a 22-kDa single-domain enzyme and was shown to possess high N

107 sed fractionation of intact proteins (10-223 kDa) from complex protein mixtures.

108 the detection of high MW proteins up to 223 kDa and also revealed low abundance proteoforms that are

109 mplex has a molecular weight of more than 23 kDa and a diameter of 4.5 nm, making it the largest, str

110 subunit and the smallest of its kind, the 23-kDa polypeptide comprises a metallonuclease domain only.

111 Pfs230, a 230-kDa sexual stage protein expressed in gametocytes is an

112 Talin is a large 235-kDa protein composed of an N-terminal 45-kDa FERM (4.1,

113 e, the levels of the approximately 23- to 24-kDa protein diminish, and the full-length, approximately

114 n is expressed as an approximately 23- to 24-kDa species that colocalizes with the trans-Golgi networ

115 btain three mAb subunits of approximately 25 kDa: Fc/2, Fd', and LC.

116 s a secreted protein that circulates as a 25-kDa dimer.

117 e in human CSF, being the most abundant a 25-kDa fragment, probably resulting from proteolytic proces

118 The level of the 25-kDa APP-CTF was evaluated in three independent CSF sampl

119 The CSF level of this 25-kDa CTF is higher in subjects with autosomal dominant AD

120 Mcm10, RFC140 and DNA polymerase epsilon 255 kDa subunit in S-phase.

121 ation of the major albumin fraction band (26 kDa), reflecting a decrease in protein size.

122 e Inhibitor (HpARI), an IL-33-suppressive 26-kDa protein, containing three predicted complement contr

123 standard green fluorescent protein (GFP, 27 kDa) and the polyketide synthase DEBS1 (394 kDa).

124 s, and it encodes a small ( approximately 27-kDa) secreted protein unrelated to other cytokine famili

125 alysis showed that MBF-12, dominated by 270 kDa biopolymers, contributed the bioflocculation mechani

126 olymer strands over 75 repeat units long (28 kDa) from a single bifunctional monomer and Cu(I) .

127 he chymotrypsin-like serine protease is a 28-kDa heterodimer with optimum activity at venom's pH of 6

128 mall-molecular-mass fluorescence tracers (<3 kDa), but not larger tracers (>10 kDa).

129 Peptide fraction <3 kDa, which exhibited the highest antioxidant activities

130 minute increased the level of delivery of 3 kDa dextran 7-fold compared with passive diffusion (P =

131 propidium iodide (PI) and the delivery of 3 kDa dextran labeled with Alexa 488 were demonstrated.

132 es, most notably the fractions larger than 3 kDa, promoted plant infection by improving zoospore swim

133 s) of gp140 by stable cross-linking with a 3-kDa CD4 miniprotein mimetic, serving to block ligation o

134 rived factors have molecular masses of 10-30 kDa.

135 on year, showed that albumin fraction (15-30 kDa) and proteolytic activity were negatively correlated

136 ity MS imaging of high molecular weight (>30 kDa) proteins, and the rapid analysis of formalin-fixed

137 on with the proteins of molecular weight >30 kDa.

138 ized intact proteins (i.e., 10 kDa < Mw < 30 kDa), respectively, termed bottom-up and top-down proteo

139 for AtCPSF30, an Arabidopsis ortholog of 30 kDa subunit of the Cleavage and Polyadenylation Specific

140 TNFalpha-stimulated gene-6 (TSG6), a 30-kDa protein generated by activated macrophages, modulate

141 186E) that resulted in NS1 binding to the 30-kDa subunit of the cleavage and polyadenylation specific

142 expressing the Mycobacterium tuberculosis 30-kDa major secretory protein (r30/antigen 85B [Ag85B]) (r

143 for detection that is 150 kDa in ice and 300 kDa in 100 nm thick samples of dense biological material

144 multimeric G85R SOD1YFP of approximately 300 kDa or >300 kDa that had been cross-linked.

145 85R SOD1YFP of approximately 300 kDa or >300 kDa that had been cross-linked.

146 cordings, microinjection of cross-linked 300 kDa increased excitability by depolarizing the resting m

147 The effect of cross-linked 300 kDa on potassium current was reduced by removing Na(+) f

148 at boundary element association factor of 32 kDa (BEAF-32) and DREF mediates a transcriptional progra

149 cAMP-regulated neuronal phosphoprotein of 32 kDa feedback, and synaptic plasticity were greater in 8-

150 nd cAMP-regulated neuronal phosphoprotein 32 kDa [DARPP-32], and cAMP responsive element binding prot

151 of just 4 kDa or 12% (GAPDH, 36 kDa; PS6, 32 kDa) in each of 129 single cells.

152 novo mutations in the gene encoding the 330-kDa triple functional domain (TRIO) protein associated w

153 of how NBP35 (Nucleotide-Binding Protein 35 kDa), the heteromeric partner of CFD1 in metazoa, functi

154 This 35 kDa water-soluble protein provides specific environment

155 omonas aeruginosa (type I-F) relies on a 350 kDa CRISPR RNA (crRNA)-guided surveillance complex (Csy

156 A-kinase anchor protein 350 kDa (AKAP350A, also called AKAP450/CG-NAP/AKAP9) is a la

157 differences of just 4 kDa or 12% (GAPDH, 36 kDa; PS6, 32 kDa) in each of 129 single cells.

158 ation is presented here, focusing on the 360 kDa (alphabetagamma)2 heterohexameric AC from Xanthobact

159 known as LifA), a chromosomally encoded 365-kDa protein.

160 Eluates from gel regions equivalent to 38 kDa were analyzed by liquid chromatography-tandem mass s

161 kDa) and the polyketide synthase DEBS1 (394 kDa).

162 gram scale with molecular weights up to 27.4 kDa (128mer, 7.9 g) using an iterative exponential growt

163 haracterised by aberrant deposition of a 5.4 kDa protein called medin within the medial layer of larg

164 flux of fluorescein isothiocyanate-dextran 4 kDa, and mRNA expression of tight junctions.

165 ns with molecular mass differences of just 4 kDa or 12% (GAPDH, 36 kDa; PS6, 32 kDa) in each of 129 s

166 tified by mass spectrometry as a small (13.4-kDa) protein related to the gSG7 protein of Anopheles ga

167 e (89)Zr chelator desferroxamine B via a 3.4-kDa PEG linker.

168 protein complexes, up to approximately 30-40 kDa.

169 , of molecular masses up to approximately 40 kDa, and with single-species sensitivity easily demonstr

170 dentify the proline-rich Akt substrate of 40 kDa (PRAS40) as the unique downstream effector of TGF-al

171 ion of AKT and proline-rich AKT substrate 40 kDa (PRAS 40), which in turn activated mTOR.

172 ion and invariably share a approximately 400 kDa five-subunit catalytic core.

173 ds, we present a structural model of the 400-kDa Cas14-Cas2-32 complex from Pectobacterium atroseptic

174 a (PPARgamma) at Asp64, thus generating a 41 kDa fragment.

175 s labeled a nonglycosylated approximately 41-kDa protein (spx1) on Western blots, and the signal was

176 A 43 kDa band, identified as creatine kinase by proteomic ana

177 Rapsyn, a 43 kDa scaffold protein, is required for the clustering of

178 d substrate, growth-associated protein of 43 kDa, that is independently implicated in trafficking of

179 (transactive response DNA binding protein 43 kDa) is a hallmark of certain forms of amyotrophic later

180 g protein TDP-43 (TAR DNA binding protein-43 kDa).

181 The 43-kDa trans-activating response region DNA-binding protein

182 e major target of activator binding, the 430 kDa Tra1 protein, is resolved with an average resolution

183 The 430 kDa Tra1 subunit and its human homolog the transformatio

184 lthough full-length K15P is approximately 45 kDa, numerous lower-molecular-weight forms of the protei

185 The isolated protein, a 45-kDa monomer, lacks catalytic activity but becomes active

186 inish, and the full-length, approximately 45-kDa K15P protein accumulates.

187 DNA encoding a full-length, approximately 45-kDa K15P reporter protein is expressed as an approximate

188 235-kDa protein composed of an N-terminal 45-kDa FERM (4.1, ezrin-, radixin-, and moesin-related prot

189 La/SS-B (or La) is a 48 kDa RNA-binding protein and an autoantigen in autoimmune

190 ed in transfected CHO cells appeared as a 48-kDa protein.

191 m horse spleen ferritin, a approximately 490 kDa protein complex approximately 20-fold larger than th

192 inorganic Fe fraction with Mp = 14.7 +/- 0.5 kDa was also resolved from the DOM-associated fraction.

193 sera recognized a doubled band of about 14.5 kDa and this recognition was inhibited by nPho d 2.

194 The 21.5 kDa human enzyme that mitigates this damage by conversio

195 sites in alpha-casein, an approximately 23.5 kDa phosphoprotein that showed eight of nine known phosp

196 age mass of proteolytic IgG peptides (>/=4.5 kDa) and produce peptides which uniquely derive from sin

197 f Fenton reaction to degrade pectin into 5.5 kDa within only 35 minutes.

198 cular imaging because of its small size (6.5 kDa), which satisfies the precondition for efficient tum

199 oiety for integrin-targeting, as well as a 5 kDa PEG chain that passivates the construct and enables

200 mately 20 poly(ethylene glycol) chains (MW 5 kDa) per 100 nm(2) prolong circulation times, irrespecti

201 how that, for a 15 kDa polyelectrolyte, a 50 kDa dialysis membrane is not sufficient to remove all PA

202 d enolase, were identified at 12, 40, and 50 kDa, respectively.

203 ly 70 kDa), and isoform-C ( approximately 50 kDa).

204 ensatory suppressor mutation in the lower 50 kDa sub-domain (myo2-E1-Sup1) that reverses the inabilit

205 had an apparent native molecular mass of 50 kDa, as predicted by amino acid sequencing and mass anal

206 e, the myo2-E1 mutation affects the upper 50 kDa sub-domain of the myosin II heavy chain, and cells c

207 d hard cheese of a group of dextrans (10-500 kDa) were found to be in the same order of magnitude wit

208 that add up to a molecular mass of about 500 kDa, TFIIH is also essential for nucleotide excision rep

209 mutations in the gene SACS, encoding the 520 kDa protein sacsin.

210 p54 (encoding signal recognition particle 54 kDa).

211 and Golgi reassembly stacking protein of 55 kDa (GRASP55) were originally identified as Golgi stacki

212 Interestingly, three 56 kDa selenium-binding proteins putatively involved in per

213 Herein, we introduce a novel ca. 1.6 kDa SMA-based polymer with styrene:maleic acid moieties

214 As early secreted antigenic target of 6 kDa (ESAT-6) of Mycobacterium tuberculosis (Mtb) is an e

215 The type VII secretion system ESX-1 [6-kDa early secretory antigenic target (ESAT-6) secretion

216 did not store EGF, synthesized as a single 6-kDa domain in pro-EGF, but rather expressed intact pro-E

217 ting IFN-gamma production triggered by the 6-kDa early secretory antigen target (ESAT-6), taking into

218 M. tuberculosis 6-kDa early secretory antigenic target (ESAT-6) is a known

219 crease in the detection of proteins above 60 kDa, compared to one-dimensional (1D) RPC.

220 NBs are large (>60 kDa) toxins that target nucleic acids (DNA, tRNA or rRNA

221 ect 0.5 ppm of HCP with molecular weight >60 kDa, such as rPLBL2.

222 e of SST14 oligomeric assemblies of 50 to 60 kDa that were visualized by gel electrophoresis, nanopar

223 ibitors of Cholinesterase A (Ric-8A) is a 60-kDa cytosolic protein that has chaperone and guanine nuc

224 The enzyme forms a homodimer of two 60-kDa subunits.

225 specific recruitment of an approximately 600-kDa endogenous isoform of Nesprin1 (Nes1(600kDa)) and of

226 ecifically via upregulation of the OSGIN1-61 kDa isoform.

227 ion between the 20 kDa amino terminus and 65 kDa carboxy terminus, after proteolytic processing.

228 man complement C9 protein ( approximately 65 kDa) is a member of the complement pathway.

229 Golgi reassembly stacking protein of 65 kDa (GRASP65) and Golgi reassembly stacking protein of 5

230 study confirms a role for the C-terminal 65 kDa domain in directing insect specificity.

231 We demonstrate the C-terminal 65 kDa to be labile in native proteolytic conditions in abs

232 GLUtamate Transporter 1 (VGLUT1) and the 65 kDa isoform of glutamic acid-decarboxylase (GAD65) as ma

233 These findings indicate that the 65 kDa protein encoded by CPSF30-L mediates nitrate signali

234 s restored by expression of the wild-type 65 kDa encoded by CPSF30-L.

235 lularly by serine proteases, generating a 65-kDa form lacking the first two scavenger receptor cystei

236 eat shock protein 47 (Hsp47/SERPINH1) and 65-kDa FK506-binding protein (FKBP65/FKBP10), have been sho

237 present a structure of the approximately 650-kDa functional replisome of bacteriophage T7 assembled o

238 The 66-kDa Src homology 2 domain-containing protein (p66Shc) is

239 urvival in schwannoma cells acting via 37/67 kDa non-integrin laminin receptor (LR/37/67 kDa) and dow

240 kDa non-integrin laminin receptor (LR/37/67 kDa) and downstream ERK1/2, PI3K/AKT and FAK signalling

241 est that PrP(C) and its interactor, LR/37/67 kDa, could be potential therapeutic targets for schwanno

242 idge boutons contain normal levels of the 67 kDa isoform of glutamic acid decarboxylase (GAD67) prote

243 chin-3-gallate (EGCG) signals ECs via the 67 kDa laminin-receptor (67LR) resulting in protein kinase

244 rc-associated substrate during mitosis of 68 kDa (Sam68) as a novel signaling molecule in DNA damage

245 either relatively small peptides (i.e., 0.7 kDa < Mw < 3.0 kDa) or small to medium sized intact prot

246 most entirely monomeric (molar mass M = 45.7 kDa) in dilute aqueous solution with a trace amount of h

247 a stable dimer with a molecular mass of 70.7 kDa in its native form.

248 weight PLGA polymers (approximately 25 and 7 kDa) to achieve different drug release profiles, with a

249 and structural characterisation of a novel 7 kDa T7 protein, Gp5.7, which adopts a winged helix-turn-

250 inding scaffold because of its small size (7 kDa), high thermal stability (Tm of 98 degrees C), and a

251 the bacterial RNA polymerase (RNAP) by the 7 kDa T7 protein Gp2.

252 uble form of the full-length approximately 7-kDa cytoplasmic C terminus in cultured cells and purifie

253 The 7-kDa N-terminal src-homology 3 domain of Drosophila signa

254 ecular weight oligomers ( approximately 8-70 kDa), and these were now far more bioactive: they impair

255 We found that MfP (approximately 70 kDa) binds to macrophage-TLR4 and triggers nuclear facto

256 mately 90 kDa), isoform-D ( approximately 70 kDa), and isoform-C ( approximately 50 kDa).

257 omeostasis depends on heat shock proteins 70 kDa (Hsp70s), a class of ubiquitous and highly conserved

258 ]) into a recombinant secreted N-terminal 70 kDa fragment (rF70K) and the full-length fibronectin (rF

259 shock protein A2 (HSPA2), a member of the 70 kDa heat shock protein (HSP70) family, plays an importan

260 The 70 kDa heat shock protein Hsp70 has several essential funct

261 at three molecules ranging from 100 Da to 70 kDa permeated into a preclinical glioblastoma model at r

262 Using 70 kDa dextran as a probe, untreated HUVECs yielded a Pd th

263 hase (FAS), filamin-A, heat shock cognate 70-kDa protein, and OGT were confirmed by co-immunoprecipit

264 ue exposed to hypoxia, induced heat-shock 70-kDa protein-1-like (HSPA1L) expression stabilized hypoxi

265 proteins form an obligate approximately 700-kDa superassembly with a broad surface suitable for memb

266 yrP1 and AtPyrP2 were estimated at 46 and 72 kDa, suggesting dimers.

267 ne interactions of full-length mammalian 72-kDa cytochrome P450-cytochrome b5 complex in lipid bilay

268 UL31 is predicted to encode a 74-kDa protein, referred to as pUL31, containing a bipartit

269 f Nrf1 by the proteasome yields an active 75 kDa fragment [4].

270 ts shorter form (which we estimated to be 75 kDa [2]) were suppressed by high concentrations of inhib

271 , CLOCK-BMAL1 exists in an approximately 750-kDa complex.

272 in-containing leukocyte phosphoprotein of 76 kDa (SLP-76) plays a crucial role in T cell activation b

273 nificant decrease in the intensity of the 76-kDa band.

274 plement is activated upon binding of the 774-kDa C1 complex, consisting of the recognition molecule C

275 rone GRP78/BiP (glucose-regulated protein 78 kDa/binding immunoglobulin protein) modulates protein fo

276 Here, we report that the stress-inducible 78-kDa glucose-regulated protein (GRP78/HSPA5), a key regul

277 m prostate cancer patients identified the 78-kDa glucose-regulated protein (GRP78) as one such target

278 e up-regulation of chaperones such as the 78-kDa glucose-regulated protein (GRP78, also referred to a

279 GSS subtypes exclusively associated with 6-8 kDa PrP(res) have often been considered as non-transmiss

280 ese results highlight the relevance of the 8 kDa domain of Polmu for accurate and efficient NHEJ, but

281 sulin-sensitive tissues (DAPIT), and the 6.8-kDa proteolipid.

282 body (IgG; 150 kDa) and its minibody (Mb; 80 kDa) format were functionalized with the chelator 1,4,7-

283 e an L1 fragment with a molecular mass of 80 kDa (L1-80).

284 n this axis as laminin alpha2, likely its 80-kDa fragment from the C terminus, was found to be transp

285 turbed assembly of the holoenzyme at the 830 kDa stage.

286 rotein-ligand complex, ranging from 53 to 85 kDa), and the results are consistent with data previousl

287 d that FplA is expressed as a full-length 85-kDa outer membrane-embedded protein or as a truncated ph

288 hat they have a weight average Mw of 0.4-0.9 kDa and a lignin-like structure rich in the beta-5' moie

289 = 29-36, with an average MW of 51.1 +/- 2.9 kDa.

290 RF excluding transit peptides encoded a 64.9 kDa protein that was expressed in E. coli, and purified

291 CKS proteins are small (9-kDa) polypeptides that bind to a subset of the cyclin-de

292 are expressed: isoform-A ( approximately 90 kDa), isoform-D ( approximately 70 kDa), and isoform-C (

293 Heat-shock protein of 90 kDa (Hsp90) is an essential molecular chaperone that ado

294 and tumour angiogenesis through a unique 90 kDa form of VEGF (VEGF90K).

295 The 90-kDa heat shock protein (Hsp90) chaperone system affects

296 The 90-kDa heat shock protein (Hsp90) is a widely conserved and

297 olecular weight of which appears to be 90-95 kDa.

298 Small Angle X-ray Scattering studies of a 97 kDa fragment spanning the topoisomerase and 10 (HhH)2 do

299 onent, Mycoplasma Ig protease (MIP), is a 97-kDa serine protease that is able to cleave off the VH do

300 ystems with molecular weights of hundreds of kDa.