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1 r after rearrangements of the locus encoding kappa-chain.
2 lambda and 14 Abs more frequently expressed kappa chains.
3 23F-specific Abs had predominantly kappa chains.
4 vy (IGHG1a) together with a light (lambda or kappa) chain.
5 ozyme-specific IgM nor the secretion of free kappa-chains.
6 had amino acids infrequently found in other kappa-chains.
7 assayed in the context of the immunoglobulin kappa chain 3' enhancer and associated binding proteins,
8 bind to adjacent sites in the immunoglobulin kappa chain 3' enhancer and generate a potent transcript
9 of these proteins bind to the immunoglobulin kappa chain 3' enhancer, which is developmentally regula
10 , and Gm(21) (odds ratio 7.3, P = 0.005) and kappa-chain allotype Km(3) (odds ratio 7.3, P = 0.005) w
11 ost allelically included B cells express two kappa chains, although rare dual-lambda cells are also o
12 all part of a sequence belongs to a heavy or kappa chain and predict its precise localization in the
13 terodimers can be detected readily between a kappa-chain and a chimera consisting of a heavy chain va
14 for various fragments, from 11 to 75 in the kappa chains, and from 23 to 189 in the heavy chains.
17 ion of the locus encoding the immunoglobulin kappa-chain complex (Igk) requires expression of the pre
20 ted a wider range of elbow angles than their kappa chain counterparts, and that the lambda light chai
21 cell lymphopenia by measuring immunoglobulin kappa chain-deletion recombinant excision circles and fo
22 lent reagents that bound only one of the two kappa-chains, dual kappa B cells responded suboptimally
27 , transcriptional induction of rearranged Ig kappa-chain gene in response to LPS was suppressed by PF
29 CD32B or CD32C, and IgG1 H chain (IGHG1) and kappa-chain (IGKC) polymorphisms determining allotypes d
30 s (NF-AT), nuclear factor for immunoglobulin kappa chain in B cells (NF-kappa B/Rel), activator prote
31 but not to nuclear factor for immunoglobulin kappa chain in B cells or activator protein 1 motifs.
32 e heavy (mu) chains and two light (lambda or kappa) chains in association with a heterodimer of Igalp
33 istone H3 at Lys27 (H3K27me3) throughout the kappa-chain joining region (J(kappa)) to the kappa-chain
34 ransgene consisting of murine immunoglobulin kappa-chain leader sequence coupled to sequence coding f
35 rangements in immunoglobulin heavy (IgH) and kappa chain loci, but increased sterile transcription an
36 g this TCR Tg mouse with mice expressing the kappa chain of mAb 36-71, we found that kappa-specific T
37 ppaB signaling is dispensable, predominantly kappa-chain-positive B cells are generated, which underg
39 nd KM allotypes-genetic markers of gamma and kappa chains, respectively-are associated with immune re
40 nd KM allotypes-genetic markers of gamma and kappa chains, respectively-play in the outcome of hepati
41 e synthesized a panel of mAbs from alpha and kappa chain sequences present in the KD arterial wall an
43 Hbs using antibody either to human IgG or to kappa chains, the anti-Hb antibody demonstrated specific
45 to residues 145-159 and 188-203 of human Ig kappa-chains to peptide-specific mouse T cell hybridomas
46 genesis of the heavy chain variable (VH) and kappa-chain variable (Vk) genes separately, then combini
47 f the normal stop codon, this portion of the kappa chain was composed of 128 amino acids (rather than
48 to the N-terminal leader sequence of the Ig kappa-chain, was transfected transiently into COS-7 cell
49 gements in the locus encoding immunoglobulin kappa-chain, we define here two distinct, consecutive ph
50 we found that cells expressing two distinct kappa-chains were 1.4-3% of all B cells and that they we
51 region, which is one residue longer than in kappa chains, with glycine occurring most frequently at
52 ultaneous expression of both IgH-mu- and IgL-kappa-chains, without progressing through the stage of I
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