ライフサイエンスコーパス: killer T-cell

1 clude the gamma-delta T cell and the Natural Killer T cell.

2 n of alphabeta T cells and invariant natural killer T cells.

3 t of alphabeta T cells and invariant natural killer T cells.

4 f conventional T cells and invariant natural killer T cells.

5 CD1d presents lipid antigens to natural killer T cells.

6 t T-cell subsets to favor regulatory natural killer T cells.

7 e conventional CD4+CD3+ T cells, not natural killer T cells.

8 restricted CD4+ T cells but, rather, natural killer T cells.

9 subgroup of T cells, CD1d-restricted natural killer T cells.

10 high affinity to CD1d and stimulates natural killer T cells.

11 t to increased cytolytic activity of natural killer T cells.

12 t of B, alphabetaT, gammadeltaT, and natural killer T cells.

13 out (beta2M-/-) mice lack CD8+ T and natural killer T cells.

14 al killer cells but lack Valpha14(+) natural killer T cells.

15 or dying cells for eliciting tumor-specific killer T cells.

16 ding a block in EBNA1 presentation to CD8(+) killer T cells.

17 ecialized subset of T cells known as natural killer T cells.

18 dependent of CTLs, natural killer or natural killer T cells.

19 kemic cells by human CD5(+) cytokine-induced killer T cells.

20 e innate immune system and invariant natural killer T cells.

21 are the major endogenous ligands of natural killer T cells.

22 osa-associated invariant T cells and natural killer T cells.

23 ransmission of HIV and stimulator of natural killer T-cells.

24 esents IL-15 in trans to neighboring natural killer/T cells.

25 Naive CD8 T cells, natural killer T cells and a subset of memory CD4 T cells bind C

26 s whose maintenance depends on help (such as killer T cells and B cells).

27 regulatory T cells, dendritic cells, natural killer T cells and B cells.

28 CD4 T cells, together with invariant natural killer T cells and gammadelta T cells, receive strong TC

29 T cell apoptosis, depleting hepatic natural killer T cells and inducing proinflammatory cytokine pol

30 llergy include the role of invariant natural killer T cells and influences of dietary components, suc

31 specialized T-cell lineages such as natural killer T cells and innate mucosal-associated invariant T

32 As natural killer T cells and liver injury are central in liver reg

33 ers of microparticles from invariant natural killer T cells and macrophages/monocytes (CD14(+)), whic

34 In addition to natural killer T cells and mucosal-associated invariant T (MAIT

35 ly confined to TCRs from innate-like natural killer T cells and mucosal-associated invariant T cells,

36 CD4 and natural killer T cells and neutrophils were markedly reduced in

37 is (P < 0.01), together with reduced natural killer T cells and raised interleukin (IL)-12 and IL-18.

38 d for development of CD4(+) T cells, natural killer T cells and regulatory T cells.

39 ponse of natural killer cells and of natural killer T cells and the Th1 polarization of antigen-speci

40 er T-cell response, characterized by natural killer T-cell and neutrophilic inflammation.

41 to effectively stimulate CD8 T cell, natural killer T cell, and natural killer cell immunity.

42 CD4+CD25+ Foxp3+ regulatory T cells, natural killer T cells, and approximately 25% of NK cells.

43 les for conventional CD4(+) T cells, natural killer T cells, and CD4(+)CD25(+)FoxP3(+) Tregs in AKI p

44 t on the presence of regulatory host natural killer T cells, and expression of CD1d on donor marrow b

45 al killer cells, gammadelta T cells, natural killer T cells, and innate-like CD8+ T cells) are spatia

46 repertoire, near-to-absent invariant natural killer T cells, and severely diminished mucosal-associat

47 esidual host T cell subsets favoring natural killer T cells, and the low incidence of GVHD was associ

48 arge cell; and 1 each had extranodal natural killer/T cell, angioimmunoblastic, and precursor T-lymph

49 ent norepinephrine increases hepatic natural killer T cell apoptosis, depleting hepatic natural kille

50 Natural Killer T cells are a distinct lymphocyte lineage that re

51 ta T lymphocytes and CD1d-restricted natural killer T cells are classified as innate T lymphocytes, w

52 Invariant natural killer T cells are found in low numbers in the airways o

53 Natural killer T cells are immunoregulatory cells, which have im

54 Natural killer T cells are mediators of important regulator and

55 els of allergic asthma indicate that natural killer T cells are required for the development of aller

56 autoreactive recognition of CD1d by natural killer T cells, are indispensable for the binding of an

57 luding both natural killer cells and natural killer T cells, are unusually abundant in the liver.

58 d-tetramers, antibodies specific for natural killer T cells, as well as reverse-transcriptase-polymer

59 n Th2 inflammation such as invariant natural killer T cells, basophils, and interleukin-9 are importa

60 (GFP), revealed CD4+ memory T cells, natural killer T cells, basophils, mast cells, and eosinophils a

61 ressed in activated human CD8(+) and natural killer T cells, both of which have been implicated in as

62 essor NKAP is required for invariant natural killer T cell but not conventional T cell development.

63 c lineage T cells and into invariant natural killer T cells but did not signal the differentiation of

64 We enumerated invariant natural killer T cells by flow cytometry with the use of CD1d te

65 cells before and after activation of natural killer T cells by ligand alpha-galactosylceramide.

66 ion of CD1d-restricted semiinvariant natural killer T cells by using the CD1d ligand alpha-galactosyl

67 gammadelta and natural killer T cells can also play a role in protective immuni

68 We show that antitumor killer T cells can be detected in patients with both pro

69 The ability of killer T cells carrying the CD8 antigen to detect tumour

70 urally occurring regulatory T cells, natural killer T cells, CD4(+) and CD8(+) T lymphocytes, margina

71 c Th2 cells did not require B cells, natural killer T cells, CD8(+) T cells, or IFNgamma.

72 o deficient in natural killer cells, natural killer T cells, CD8+ T lymphocytes, and TCRgammadelta in

73 )-binding kinase/T-LAK (lymphokine-activated killer T cell) cell originating protein kinase (PBK/TOPK

74 ytokines expression of dendritic and natural killer T cells co-culture.

75 particles from CD14(+) and invariant natural killer T cells correlated with levels of alanine aminotr

76 The frequency of natural killer T cells correlated with the level of anti-HBs (P

77 ted into transgenic mice deficient in NK and killer T-cell cytotoxicity generated by expressing dipht

78 4 days before partial hepatectomy to natural killer T cells- deficient mice or to anti CD1d1-treated

79 Natural killer T cells- deficient or mice injected with anti CD1

80 Alcohol-fed natural killer T cell-deficient Jalpha281(-/-) mice express a de

81 Hepatic natural killer T cell depletion leads to Th-1 polarization of he

82 conditional knockout mice, invariant natural killer T cell development is blocked at the double-posit

83 a role of the SAP-Fyn interaction in natural killer T cell development through the ability of SAP-Fyn

84 ses a similar block in the invariant natural killer T cell development, indicating that NKAP and hist

85 e defects in natural killer cell and natural killer T cell development, suggesting a role for MEF in

86 sphate receptor S1pr1 as well as for natural killer T cell development.

87 onally interact to control invariant natural killer T cell development.

88 ature thymocytes for trafficking and natural killer T cell development.

89 Stimulation of natural killer T cells during alcohol consumption induces seriou

90 Natural killer T cells express a conserved, semi-invariant alpha

91 The natural killer T cells expressed an invariant T-cell receptor an

92 Natural killer T cells expressing 'invariant' T cell receptor al

93 Natural killer T cells expressing an invariant T-cell receptor (

94 ding regulatory T and CD1d-dependent natural killer T cells, fail to develop.

95 PE DHC enhances EAE in mice lacking natural killer T cells, fails to enhance EAE in Toll-like recept

96 This report analyzes the role of natural killer T cells, Fas, and TNF-alpha in a model of chronic

97 syl ceramide (alpha-GalCer) to mouse natural killer T cells, formally demonstrating both the in vitro

98 We show here that natural killer T cells from UV-irradiated donor mice function as

99 lopment of colitis involves not only natural killer T-cell functions, but also requires IL-13 product

100 Invariant natural killer T cells have a distinct developmental pathway fro

101 ualitative defects in CD1-restricted natural killer T cells have been reported in several autoimmune-

102 10 years since the first workshop on natural killer T cells helped to launch a growth phase for this

103 Natural killer T cell hybridomas with identical T cell antigen r

104 r, little is known about the role of natural killer T cells in alcohol-induced liver injury.

105 the role of vitamin D and CD8(+) and natural killer T cells in asthma exacerbation in a genome-wide g

106 generated and the pathogenic role of natural killer T cells in asthma.

107 rent study is to explore the role of natural killer T cells in impaired liver regeneration.

108 tion between the number of invariant natural killer T cells in the airway and disease severity.

109 e studied the frequency of invariant natural killer T cells in the airways of subjects with mild or m

110 in mice indicating a requirement for natural killer T cells in the development of allergen-induced ai

111 l consumption induces an increase of natural killer T cells in the liver and a high sensitivity of he

112 ss the frequency and distribution of natural killer T cells in the lungs and in the circulating blood

113 ly activated hepatic macrophages and natural killer T cells, in the absence of obesity or insulin res

114 In alcohol-consuming animals, liver natural killer T cells increase, and further activation by alpha

115 Using natural killer T cells (iNKT cell) as a model of a T cell subset

116 Invariant natural killer T cells (iNKT cells) are a small subset of immuno

117 de (alphaGC) that activate invariant natural killer T cells (iNKT cells) are being developed as poten

118 Invariant natural killer T cells (iNKT cells) are critical for host defens

119 Invariant natural killer T cells (iNKT cells) are innate-like lymphocytes

120 Invariant natural killer T cells (iNKT cells) are innate-like T cells impo

121 Invariant natural killer T cells (iNKT cells) are innate-like T cells that

122 Invariant natural killer T cells (iNKT cells) are innate-like T lymphocyte

123 Invariant natural killer T cells (iNKT cells) are involved in the host def

124 Invariant natural killer T cells (iNKT cells) are lipid-sensing innate T c

125 Glycolipid ligands for invariant natural killer T cells (iNKT cells) are loaded onto CD1d molecul

126 lock in the development of invariant natural killer T cells (iNKT cells) at their earliest progenitor

127 echanisms of activation of invariant natural killer T cells (iNKT cells) by microbes: direct activati

128 Invariant natural killer T cells (iNKT cells) can produce copious amounts

129 Invariant natural killer T cells (iNKT cells) express a restricted T cell

130 Invariant natural killer T cells (iNKT cells) have a prominent role during

131 Invariant natural killer T cells (iNKT cells) have an innate immunity-like

132 Mouse invariant natural killer T cells (iNKT cells) provide cognate and noncogna

133 Invariant natural killer T cells (iNKT cells) rapidly produce effector cyt

134 Invariant natural killer T cells (iNKT cells) respond to CD1d-presented gl

135 nteracted with innate-type invariant natural killer T cells (iNKT cells) to regulate B cell responses

136 romoted the interaction of invariant natural killer T cells (iNKT cells) with those neutrophils, a pr

137 cells, which encompass 70% invariant natural killer T cells (iNKT cells), have been found primarily p

138 pment and proliferation of invariant natural killer T cells (iNKT cells).

139 ing glycolipid antigens to invariant natural killer T cells (iNKT cells).

140 (iT) cell subsets, such as invariant natural killer T cells (iNKT) and mucosal-associated invariant T

141 V alpha14 invariant natural killer T cells (iNKT) are localized in peripheral tissue

142 kedly decreased numbers of invariant natural killer T cells (iNKT) as defined by staining with an alp

143 Invariant natural killer T cells (iNKT) cells are T lymphocytes displaying

144 ments for invariant Valpha14-bearing natural killer T cells (iNKT) in the thymus are poorly understoo

145 re regulated via recipient invariant natural killer T-cell (iNKT) interleukin-4-driven expansion of d

146 Invariant Natural Killer T-cells (iNKT-cells) are an attractive target for

147 CD1d-restricted Valpha24-invariant natural killer T cells (iNKTs) are important in immunoregulation

148 have previously found that invariant natural killer T cells (iNKTs) are involved in CM allergy sensit

149 stricted Valpha24-Jalpha18-invariant natural killer T cells (iNKTs) are potentially important in tumo

150 Invariant natural killer T cells (iNKTs), a small population characterized

151 cells, regulatory T cells, invariant natural killer T cells [iNKTs], NK cells, and dendritic cell sub

152 nnate lymphocyte lineages, including natural killer T cell, innate lymphoid cell, mucosal-associated

153 identified CD1d-restricted invariant natural killer T cells is a matter of controversy.

154 as been shown that the proportion of natural killer T cells is markedly elevated during liver regener

155 ber of the innate immune system, the natural killer T cell, is activated during bacterial infections.

156 subset of CD4+ T helper 1 cells and natural killer T cells, is involved in lymphocyte homing into th

157 uding the Hut 78 T-cell leukemia, JY natural killer T-cell leukemia, Daudi B-cell lymphoma, HeLa, and

158 enhanced by coadministration of the natural killer T-cell ligand 7DW8-5, which heightened the produc

159 stocompatibility complex (MHC) nonrestricted killer T-cell line (TALL-104) as a new marrow purging ag

160 NKAP in selection into the invariant natural killer T cell lineage.

161 (thymocytes) to either the CD4 helper or CD8 killer T-cell lineages correlates precisely with their T

162 The clinical outcome of extranodal natural killer T-cell lymphoma (ENKTL) has improved substantiall

163 Extranodal natural killer T-cell lymphoma (NKTCL), nasal type, is a rare an

164 Extranodal natural killer-T-cell lymphoma (NKTCL) of nasal type is a malign

165 ell lymphoma (n = 2), and extranodal natural killer/T-cell lymphoma (n = 2).

166 eripheral T-cell lymphoma (PTCL) and natural killer/T-cell lymphoma (NKTCL) are rare and heterogeneou

167 Natural killer/T-cell lymphoma (NKTCL) is a rare, aggressive for

168 In the current study, using natural killer/T-cell lymphoma (NKTL) as a disease model, we fou

169 tly overexpressed in the majority of natural killer/T-cell lymphoma (NKTL), an aggressive lymphoid ma

170 dence of AITL, extranodal nasal-type natural killer/T-cell lymphoma and NK-cell leukemia (ENKCL), and

171 luding acute lymphoblastic leukemia, natural killer/T-cell lymphoma, and acute myeloid leukemia, as w

172 ll as non-Hodgkin, Hodgkin and nasal natural killer/T-cell lymphomas, although all three TET family g

173 ly caused by Wegener granulomatosis, natural killer/T-cell lymphomas, cocaine abuse, or infections.

174 rovided evidence that T lymphocytes, natural killer T cells, mast cells, and B cells also enter adipo

175 IL-9 is produced by T cells, natural killer T cells, mast cells, eosinophils, and innate lymp

176 the activation of T lymphocytes and natural killer T cells, maturation of DCs, secretion of proinfla

177 remains slow, but IL-13 produced by natural killer T cells may be involved.

178 d T helper type 2-like properties of natural killer T cells may originate largely from differences in

179 Highly active killer T cells mediate a stable standoff during controll

180 Natural killer T cell-mediated apoptosis proceeds by the Fas pat

181 nity and compromised the function of natural killer T-cell-mediated innate immunity.

182 Hepatic natural killer T cells modulate liver injury by balancing local

183 ymphoid cells, natural killer cells, natural killer T cells, mucosal-associated invariant T cells, an

184 ences in the percentages of T cells, natural killer T cells, natural killer (NK) cells, macrophages a

185 Depletion of natural killer-T cells, natural killer cells, plasma cells, and

186 tration, while natural killer cells, natural killer T cells, neutrophils and dendritic cells hepatic

187 a type of white blood cell known as natural killer T cell (NKT cell).

188 eceptors can affect innate immunity [natural killer T cell (NKT) and gamma-delta T-cell receptor], an

189 uced expression of genes critical to natural killer T cell (NKT) and gammadelta T-cell differentiatio

190 (hi)Ly6G(-) cells also enhance liver natural killer T cell (NKT) death in an Fas-dependent manner.

191 colipid activates innate Valpha14(+) natural killer T cell (NKT) lymphocytes, which drive DC maturati

192 mpaired thymic selection of Valpha14 natural killer T cells (NKT cells) and a subsequent reduction of

193 antigen receptor (TCR) expressed by natural killer T cells (NKT cells) and the antigen-presenting mo

194 ass I homolog CD1d are recognized by natural killer T cells (NKT cells) characterized by either a sem

195 lls (T regulatory cells [Tregs]) and natural killer T cells (NKT cells) each protect against graft-ve

196 Natural killer T cells (NKT cells) expressing a semi-invariant C

197 ingolipids (GSLs) to activate type I natural killer T cells (NKT cells) has been known for 2 decades.

198 Natural killer T cells (NKT cells) have stimulatory or inhibitor

199 Loss of natural killer T cells (NKT cells) in CD1 knockout mice resulted

200 this study is to identify invariant natural killer T cells (NKT cells) in cellular infiltrate of hum

201 CD1d-restricted natural killer T cells (NKT cells) possess a wide range of effec

202 Natural killer T cells (NKT cells) recognize glycolipid antigens

203 Natural killer T cells (NKT cells) restricted by the antigen-pre

204 of a niche shared by MAIT cells and natural killer T cells (NKT cells).

205 nd thereby the effector functions of natural killer T cells (NKT cells).

206 The antigen receptor for natural killer T cells (NKT TCR) binds CD1d-restricted microbial

207 n with an IL-15-mediated increase of natural killer T-cells (NKT) and the up-regulation in liver prod

208 n-presenting cell CD1d with distinct natural killer T-cell ("NKT") populations can induce rapid gamma

209 However, after exclusion of natural killer T cells (NKTs) and gammadelta T cells by FACS, li

210 Valpha24-invariant natural killer T cells (NKTs) localize to tumors and have inhere

211 duction from CD4(+) T cells, but not natural killer T cells or innate lymphoid cells, suggesting a TH

212 by heat shock proteins, glycolipids, natural killer T cells, or dendritic cells in disease pathogenes

213 r results strongly suggest that CD4+ natural killer T cells play a prominent pathogenic role in human

214 yperreactivity, we hypothesized that natural killer T cells play an important role in human asthma.

215 Natural killer T cells play an important role in liver regenerat

216 ectly in the expansion of protective natural killer T-cell populations.

217 ndritic cells, and type 1 T cells or natural killer T cells potentially drives pathogenic inflammatio

218 mount, which results in expansion of natural killer T cells producing IL-13 (and perhaps IL-5).

219 ed expression of interferon gamma by natural killer T cells, promoting hepatocyte proliferation.

220 antibodies specific to the invariant natural killer T-cell receptor in samples of bronchoalveolar-lav

221 of gene expression of the invariant natural killer T-cell receptor.

222 n of messenger RNA for the invariant natural killer T-cell-receptor domains Valpha24 and Vbeta11 was

223 Mouse type I natural killer T cell receptors (iNKT TCRs) use a single V alpha

224 following the ligation of invariant natural killer T cell receptors to sphingolipids (SLs).

225 How viruses evade natural killer T cell recognition remains unclear.

226 Tolerance required host natural killer T-cell recognition of CD1d on donor marrow cells.

227 Natural killer and natural killer T cells remove virus-infected hepatocytes by deat

228 expressing, but not TIM-1-deficient, natural killer T cells responded to apoptotic airway epithelial

229 have evolved mechanisms to avoid the CD8(+) killer T cell responses by interfering with MHC class I

230 ion of protective CD4(+) T cells and natural killer T-cell responses against ehrlichiae.

231 ates a role for TCR beta in defining natural killer T cell specificity, despite the more restricted d

232 ctor properties resembling invariant natural killer T cells, such as copious production of cytokines

233 senting cell-mediated stimulation of natural killer T cells, supporting the idea that this mechanism

234 g the activity of natural killer and natural killer T cells that normally contribute to tumor surveil

235 t T cell subsets to favor regulatory natural killer T cells that suppress GVHD and prevent organ allo

236 t T-cell subsets to favor regulatory natural killer T cells that suppress GvHD by polarizing donor T

237 -recognition receptor, conferring on natural killer T cells the ability to sense and respond in an in

238 The hepatic natural killer T cells themselves are regulated by Kupffer-cell-

239 the innate-like effector program of natural killer T-cell thymocytes, is prominently associated with

240 of the invariant T-cell receptor of natural killer T cells to assess the frequency and distribution

241 that provides a continuous supply of potent killer T cells to curb Toxoplasma gondii growth during l

242 ild-type CD4(+) Th cells depleted of natural killer T cells to Lck(cre)IL-4Ralpha(-/lox) mice restore

243 V(alpha)14 invariant natural killer T cells (V(alpha)14iNKT cells) are thymus-derived

244 er gamma-delta T cells and invariant natural killer T cells were found to be involved in IL-17A hyper

245 FN-alpha, whereas natural killer and natural killer T cells were the main source of IFN-gamma product

246 Natural killer T cells, which are stimulated by lipids presented

247 , Kupffer cells), natural killer and natural killer T cells, which constitute the innate immune syste

248 Glycolipid reactive natural killer T cells with an invariant TCR alpha-chain (iNKT c

249 Two populations of natural killer T cells with invariant TCR alpha-chains (iNKT cel

250 d innate-like lymphocytes, including natural killer T cells, with an emphasis on the known requiremen

251 ated by IFN-gamma and CD4(+) Th1 and natural killer T cells, with lower IL-10 secretion by T cells.

252 and sputum induction were invariant natural killer T cells, with no significant differences among th