ライフサイエンスコーパス: knee pain

1 ted hallux valgus, nodal osteoarthritis, and knee pain.

2 es a clinically meaningful change in chronic knee pain.

3 me in middle-aged and older individuals with knee pain.

4 ML score is predictive of the development of knee pain.

5 ether enlarging BMLs are associated with new knee pain.

6 ects were again queried twice about frequent knee pain.

7 mproving functioning in persons with chronic knee pain.

8 ographic osteoarthritis in older adults with knee pain.

9 chair-stand time, and use of medications for knee pain.

10 distinguished by the presence or absence of knee pain.

11 herence or changes in quadriceps strength or knee pain.

12 ogy accounted for only 1 in 11 patients with knee pain.

13 is debate about benefits of acupuncture for knee pain.

14 subgroup of patients with moderate-to-severe knee pain.

15 volume loss and no significant difference in knee pain.

16 anagement and treatment of older people with knee pain.

17 is at baseline nor followup, and no baseline knee pain.

18 functional declines among older adults with knee pain.

19 ributes to the development of future chronic knee pain.

20 e prescription for older adults with chronic knee pain.

21 of blacks and 31% of whites reported hip or knee pain.

22 people with self-reported symptoms of hip or knee pain.

23 adults 65 years of age or older with chronic knee pain.

24 ion of physical disability caused by chronic knee pain.

25 s remained associated with the occurrence of knee pain.

26 ructural and nonstructural factors influence knee pain.

27 hed controls and tested for association with knee pain.

28 classified by radiography and by severity of knee pain.

29 these structural lesions and the severity of knee pain.

30 th a body mass index of 18-27 kg/m(2) and no knee pain.

31 djustment for age, sex, body mass index, and knee pain.

32 persons aged 50 years or older with chronic knee pain.

33 for conditions such as chronic low back and knee pain.

34 months on progression of cartilage loss and knee pain.

35 ound between the effusion score and frequent knee pain.

36 ly associated with the new onset of frequent knee pain.

37 followed by regional (14%) or diffuse (10%) knee pain.

38 ncreasing number of people suffering chronic knee pain.

39 moderate/severe knee pain and those with no knee pain, 12.9% and 10.9% of men (P=0.74) and 6.7% and

40 t knee pain and longitudinally with frequent knee pain 2 years after the baseline evaluation.

41 For 177 subjects with chronic knee pain, 3T magnetic resonance imaging (MRI) of both k

42 luded the WOMAC disability subscale, overall knee pain, 50-feet walk time, chair-stand time, and use

43 s experienced joint-specific improvements in knee pain (77.1% [95% CI, 73.5%-80.7%]) and in hip funct

44 ngaging their provider in a discussion about knee pain (92% versus 85%), to receive a referral to an

45 50 years or older with chronic and frequent knee pain, a Western Ontario McMaster Universities Osteo

46 use was also associated with a reduction in knee pain according to the WOMAC scores.

47 sked twice at baseline about the presence of knee pain, aching, or stiffness (classified as frequent

48 (range 0-3) and the development of frequent knee pain, aching, or stiffness (odds ratio [OR] 1.21, 9

49 niscal damage on the development of frequent knee pain, aching, or stiffness in middle-aged and older

50 of a meniscal tear was 63% among those with knee pain, aching, or stiffness on most days and 60% amo

51 hritis (adjusted OR 1.66; 95% CI 1.26-2.17), knee pain (adjusted OR 1.96; 95% CI 1.65-2.32), big toe

52 rfaces was associated with frequent incident knee pain (adjusted OR 4.19, 95% CI 1.56-11.22).

53 ores indicating more severe symptoms) and in knee pain after exercise (rated on a scale from 0 to 10,

54 points; 95% CI, -9.2 to 4.1); and score for knee pain after exercise, 3.1 and 3.3 points, respective

55 mm versus 16.4 mm; P = 0.005), reduction in knee pain after walking 50 feet (15.1 mm versus 8.7 mm;

56 hundred twenty subjects from the OAI without knee pain (age, 45-55 years) and with risk factors for k

57 nd disability were less severe in those with knee pain alone than in those with knee pain and pain el

58 elihood of patient-provider discussion about knee pain and access to surgical evaluation.

59 epidemiologic studies of knee pain, frequent knee pain and activity-related pain severity are the mos

60 se with greater quadriceps strength had less knee pain and better physical function over followup (P<

61 th greater quadriceps strength also had less knee pain and better physical function over followup.

62 re assessed by interview and the severity of knee pain and disability related to knee pain were deter

63 Knee pain and disability were less severe in those with

64 Few data exist on the association between knee pain and fracture.

65 the FOA Study, participants were asked about knee pain and had bilateral weight-bearing anteroposteri

66 Both knee pain and hip pain participants expressed similar pa

67 ustering was also associated with persistent knee pain and impaired physical functioning.

68 They were also asked about knee pain and limitations in function by using the Short

69 ith moderate-to-severe knee pain or frequent knee pain and longitudinally with frequent knee pain 2 y

70 ignificantly more common among subjects with knee pain and may contribute to pain in these individual

71 Knee pain and mobility were assessed with standard tests

72 no knee pain, and in 0% of the group with no knee pain and no ROA (P = 0.004).

73 ery 6 months thereafter in 115 patients with knee pain and OA of mainly the tibiofemoral joint.

74 Knee pain and OA should be regarded as independent risk

75 For anterior knee pain and OA, medially-directed tape decreased pain

76 Patients completed a questionnaire about knee pain and OA.

77 ody mass index (BMI)-adjusted prevalences of knee pain and osteoarthritis at later examinations were

78 nce for the effectiveness of acupuncture for knee pain and other common treatments, including exercis

79 hose with knee pain alone than in those with knee pain and pain elsewhere, even after adjusting for a

80 Similar associations were seen with knee pain and physical functioning measures.

81 of antiresorptive drugs and the presence of knee pain and radiographic changes of OA of the knee.

82 The relationship between knee pain and radiographic evidence of knee osteoarthrit

83 ians and researchers is that the severity of knee pain and related disability is worse in the presenc

84 ) were present in 12.1% of the patients with knee pain and ROA, in 20.5% of the patients with ROA and

85 (BMLs), synovitis, and effusion to frequent knee pain and severity of knee pain was examined using c

86 lay an important role in the pathogenesis of knee pain and should be studied further.

87 Secondary outcomes were knee pain and stiffness (WOMAC), average pain (NRS), int

88 The sixth patient presented with knee pain and swelling.

89 udy, the age- and BMI-adjusted prevalence of knee pain and symptomatic knee osteoarthritis approximat

90 to 25% decrease in the prevalence ratios for knee pain and symptomatic knee osteoarthritis.

91 Similarly, for those with moderate/severe knee pain and those with no knee pain, 12.9% and 10.9% o

92 sions are equally common among subjects with knee pain and those without knee pain, other periarticul

93 kling, even after adjustment for severity of knee pain and weakness.

94 Subjects were then asked about knee pain and weight-bearing anteroposterior and lateral

95 ndependently associated with the presence of knee pain and with quadriceps weakness.

96 bracing effects in individuals with anterior knee pain, and 3 investigated taping effects in individu

97 OA, in 20.5% of the patients with ROA and no knee pain, and in 0% of subjects with neither ROA nor kn

98 in, in only 3.9% of patients with ROA but no knee pain, and in 0% of the group with no knee pain and

99 explore the association between knee height, knee pain, and knee OA.

100 in states: arthritic knee pain, experimental knee pain, and pain-free.

101 cipants could identify the location of their knee pain, and trained interviewers could reliably recor

102 nce of radiographic knee OA, and severity of knee pain, and were randomized to strength training (ST)

103 lent knee symptoms and disability related to knee pain as assessed at the final visit of the Heart an

104 trogen, was associated with less severity of knee pain as assessed by WOMAC scores.

105 knees," in which the patient rated standing knee pain as severe or extreme after the washout and in

106 Efficacy was measured using self-reported knee pain at 2 years.

107 Data on self-reported knee pain at 4 time points over 12 years were analyzed i

108 A case knee was defined as absence of knee pain at baseline but presence of knee pain both tim

109 inal analyses (in 168 knees without frequent knee pain at baseline) revealed that percent denuded bon

110 years, with few women consistently reporting knee pain at each time point.

111 Change in self-reported knee pain at follow-up.

112 s but who subsequently developed new chronic knee pain at followup.

113 bjects who reported a > or = 20% increase in knee pain at the majority of their followup visits had m

114 nalysis and identified those who reported no knee pain at the time of motion analysis but who subsequ

115 osteoarthritis such as nodal osteoarthritis, knee pain, big toe pain, and self-reported osteoarthriti

116 sex, body mass index, nodal osteoarthritis, knee pain, big toe pain, joint replacement, self-reporte

117 Among persons with knee pain, bone marrow lesions were not associated with

118 nce of knee pain at baseline but presence of knee pain both times at followup.

119 associated with the presence and severity of knee pain but not with the presence of radiographic OA.

120 netic resonance imaging (MRI) are related to knee pain, but no longitudinal studies have been done.

121 or without pain elsewhere, or other pain (no knee pain, but pain elsewhere).

122 e therapy is associated with improvements in knee pain, but the cost of delivering the exercise progr

123 ignificantly better than placebo in reducing knee pain by 20 percent.

124 steoarthritis Study were queried about their knee pain by interview, and knees were assessed by magne

125 and osteoarthritis outcome score (KOOS) and knee pain by visual analogue score (VAS).

126 To investigate the links between knee pain characteristics and restricted mobility outsid

127 ected force on the patella decreased chronic knee pain compared with no tape by 16.1 mm (95% confiden

128 d radiographic features were associated with knee pain, confirming that structural abnormalities in t

129 ciation between structural abnormalities and knee pain, contrary to the 'so-called' structure-symptom

130 Knee pain decreased in both groups by a mean -2.31 (95%

131 At followup, 7 had developed new chronic knee pain defined as pain or stiffness on most days of t

132 ual primary care and participation in ESCAPE-knee pain delivered to individuals (Indiv-rehab) or grou

133 ne was approved for the treatment of chronic knee pain due to osteoarthritis and has been conditional

134 Sixty consecutive patients with knee pain due to various arthritides had a clinical exam

135 Adults age >or=65 years with chronic knee pain experience significant declines in balance and

136 ed during 3 different pain states: arthritic knee pain, experimental knee pain, and pain-free.

137 People with knee pain focused on stairs, weight, and stiffness, whil

138 Participants age >/=50 years, reporting knee pain for >6 months, were recruited from 54 inner-ci

139 The 250 patients had low back, hip, or knee pain for 3 months or longer and at least moderate d

140 rioceptive acuity in quartiles with baseline knee pain (frequent pain yes/no), WOMAC pain score, self

141 In longitudinal epidemiologic studies of knee pain, frequent knee pain and activity-related pain

142 outcome measure was a 20 percent decrease in knee pain from baseline to week 24.

143 their efficacy and safety as a treatment for knee pain from osteoarthritis.

144 ional covariates (age, sex, body mass index, knee pain), general bone mineral content, and joint spac

145 Knee pain global severity was associated with symptom di

146 and with anxiety and depression both in the knee-pain group and in the other-pain group (association

147 ain group (associations were stronger in the knee-pain group).

148 knee pain, those who did develop new chronic knee pain had higher baseline adduction moments for all

149 Patients with hip or knee pain had mean +/- SD Western Ontario and McMaster U

150 Patients with knee pain had more severe radiographic disease than did

151 Fifty-seven percent of responders with knee pain had pain in at least 2 other joint areas.

152 Provision of ESCAPE-knee pain had small cost implications, but it was more l

153 Results suggest that the prevalence of knee pain has increased substantially over 20 years, ind

154 ith a clinical diagnosis of knee OA and with knee pain have an increased risk of nonvertebral and hip

155 Novel approaches to the study of knee pain have demonstrated a strong association between

156 Most people with knee pain have multiple joint site pain.

157 Among women with knee pain, higher knee height was associated with more s

158 y the severity or responsiveness of standing knee pain in flaring and nonflaring OA knees.

159 We describe commonly used measures of knee pain in longitudinal studies and review various ana

160 ne plate exposure and prevalent and incident knee pain in patients with knee OA.

161 ynovitis are associated with fluctuations in knee pain in patients with knee OA.

162 ing tibial cartilage loss or improving WOMAC knee pain in patients with knee osteoarthritis.

163 studies, a lateral-wedge insole has reduced knee pain in patients with medial knee osteoarthritis (O

164 Given the magnitude of changes in knee pain in the active treatment group, heat retention

165 arthritis Initiative Clinical Center who had knee pain in the last 12 months were studied.

166 esent in 14.9% of patients with both ROA and knee pain, in only 3.9% of patients with ROA but no knee

167 When the differential diagnosis for acute knee pain includes an exacerbation of osteoarthritis, cl

168 Age- and BMI-adjusted prevalence of knee pain increased by about 65% in NHANES from 1974 to

169 fined knee osteoarthritis, and self-reported knee pain information from a cross-sectional, community-

170 isk factors were age, body mass index (BMI), knee pain intensity (on a visual analog scale [VAS]), lo

171 4), BMI (OR 1.26/5 units, 95% CI 1.01-1.57), knee pain intensity (OR 1.21/20 mm on VAS, 95% CI 1.00-1

172 Knee pain intensity and knee strength may mediate the re

173 utcome over 3 years, adjusting for age, BMI, knee pain intensity, disease severity, and additional po

174 ceptive inaccuracy, as well as age, BMI, and knee pain intensity.

175 verage pain (NRS), intermittent and constant knee pain (Intermittent and Constant Osteoarthritis Pain

176 For persons with chronic knee pain, Internet-delivered, physiotherapist-prescribe

177 and/or cardiac disease, extremity fracture, knee pain, intraabdominal malignancy, and stroke.

178 Chronic knee pain is a major cause of disability and health care

179 Development of knee pain is associated with an increase in BMLs as reve

180 health factors (OA severity, knee symptoms, knee pain, knee injury, body mass index, comorbidity, de

181 h knee OA, radiographic severity of knee OA, knee pain, knee motion, and quadriceps strength were als

182 on of osteoarthritis (OA) is that changes in knee pain may affect extension, thereby altering the app

183 f participants with radiographic knee OA and knee pain met recommended physical activity levels.

184 was stratified according to the severity of knee pain (mild [N=1229] vs. moderate to severe [N=354])

185 In persons with unilateral knee pain, MRI and radiographic features were associated

186 ain (n = 51), and those with neither ROA nor knee pain (n = 24).

187 groups: those with radiographic OA (ROA) and knee pain (n = 376), those with ROA and no knee pain (n

188 d knee pain (n = 376), those with ROA and no knee pain (n = 51), and those with neither ROA nor knee

189 OA patients had knee pain, needed 67% more time to complete 4 functional

190 han 50 years with moderate or severe chronic knee pain, neither laser nor needle acupuncture conferre

191 ery had helped someone they knew with hip or knee pain (not significant).

192 Primary outcomes were average knee pain (numeric rating scale, 0 [no pain] to 10 [wors

193 ed pain in individuals ages 45-65 years with knee pain, OA, and meniscal tears.

194 dertaken to examine the effect of changes in knee pain of varying magnitudes on radiographic joint sp

195 The evaluation of acute knee pain often includes radiography of the knee.

196 cial treatments are needed to manage chronic knee pain on a population level.

197 up, when analyzing mean values: reduction in knee pain on standing (24.5 mm versus 16.4 mm; P = 0.005

198 ge of responders experiencing a reduction in knee pain on standing was superior in the ginger extract

199 n of responders experiencing a reduction in "knee pain on standing," using an intent-to-treat analysi

200 aching, or stiffness (classified as frequent knee pain) on most days; absence of knee pain was the ba

201 , when compared with placebo, did not reduce knee pain or cartilage volume loss in patients with symp

202 risk factor of interest on change in risk of knee pain or change in pain severity.

203 d bone is associated with moderate-to-severe knee pain or frequent knee pain and longitudinally with

204 rs, body mass index of 19-27 kg/m(2), and no knee pain or OA on radiographs at baseline.

205 Those with knee pain or other pain were subdivided by the extent of

206 ure was associated with knee OA but not with knee pain or physical functioning.

207 than 40 years were recruited irrespective of knee pain or radiographic osteoarthritis.

208 -1.47), and baseline to 18-month increase in knee pain (OR 1.32/20 mm on VAS, 95% CI 1.06-1.65).

209 the source population in terms of age, sex, knee pain, osteoarthritis, and rheumatoid arthritis.

210 ng subjects with knee pain and those without knee pain, other periarticular lesions (including bursit

211 d knowing someone who had surgery for hip or knee pain (P < 0.0001).

212 compared with 15 of 50 (30%) persons with no knee pain (P < 0.001).

213 (P < 0.05), stair-climb time (P < 0.05), and knee pain (P < 0.05) relative to the healthy lifestyle g

214 knee height was associated with more severe knee pain (P = 0.0004 for the highest quartile versus th

215 , and in 0% of subjects with neither ROA nor knee pain (P = 0.116).

216 ze of BMLs was associated with resolution of knee pain (P for trend = 0.007).

217 ies are needed to determine whether specific knee pain patterns correlate with discrete pathologic fi

218 s assessed and recorded participant-reported knee pain patterns into 8 local areas, 4 regional areas,

219 on the basis of self-completed questions on knee pain persistence and global severity (Chronic Pain

220 wer independent associations were found with knee pain persistence.

221 imary knee OA, independent of sex, age, BMI, knee pain, physical activity, and disease severity.

222 justing for sex, age, body mass index (BMI), knee pain, physical activity, cohort, and disease severi

223 Knee pain prevalence and a clinician diagnosis of knee O

224 Arthritic Knee Pain through Exercise (ESCAPE-knee pain) program.

225 ESCAPE-knee pain provides a safe, relatively brief intervention

226 Secondary outcomes were knee pain, quality of life, global change (overall, pain

227 with a body mass index of > or =28 kg/m(2), knee pain, radiographic evidence of knee OA, and self-re

228 contributions from other impairments such as knee pain, range of motion, and quadriceps strength.

229 and a knee pain scale to measure obesity and knee pain, respectively.

230 d dorsiflexion, and 3) body mass index and a knee pain scale to measure obesity and knee pain, respec

231 RI-measured tibial cartilage volume or WOMAC knee pain score over 2 years.

232 s were constructed by dichotomizing clinical knee pain scores (median split) and knee OA grade scores

233 iscal damage and the development of frequent knee pain seems to be present because both pain and meni

234 Primary outcomes were knee pain severity (Western Ontario and McMaster Univers

235 nee symptoms were assessed by interview, and knee pain severity was evaluated using the Western Ontar

236 Knee pain severity was strongly associated with restrict

237 l contributions from selected comorbidities, knee pain severity, limitation in walking, and specific

238 fter adjustment for age, sex, walking speed, knee pain severity, physical activity, varus malalignmen

239 adjusted for age, sex, body mass index, and knee pain severity.

240 ns with obesity, associations between JH and knee pain showed higher ORs in obese participants (OR 11

241 en symptomatic, chondral lesions manifest in knee pain, swelling, and loss of function.

242 e who have had surgical treatment of hip and knee pain than whites and appear to be less likely to pe

243 e, relatively brief intervention for chronic knee pain that is equally effective whether delivered to

244 Knee pain, the primary outcome, was assessed by the WOMA

245 Among women with knee pain, there were no differences in the severity of

246 rity of community-dwelling older adults with knee pain this method enables the presence of radiograph

247 ne or more of these locations in people with knee pain.This review does not cover psychological aspec

248 Compared with those who did not develop knee pain, those who did develop new chronic knee pain h

249 ng Self-Management and Coping with Arthritic Knee Pain through Exercise (ESCAPE-knee pain) program.

250 ng Self-management and Coping with Arthritic Knee Pain through Exercise [ESCAPE-knee pain]) with usua

251 progressive knee osteoarthritis and related knee pain to identify targets for primary and secondary

252 Twelve patients with chronic knee pain unresponsive to conservative treatments and ra

253 We randomized 30 patients with chronic knee pain unresponsive to conservative treatments and sh

254 nd (b) "nonflaring knees," in which standing knee pain was absent, mild, or moderate after the washou

255 Knee pain was assessed by using the Western Ontario and

256 At baseline and at followup visits, knee pain was assessed using a visual analog scale, and

257 Increasing severity of knee pain was associated with a greater risk of falls an

258 Prevalent knee pain was associated with an increased risk of falls

259 mined whether the development of new chronic knee pain was associated with higher peak adduction mome

260 Frequent knee pain was associated with percent denuded bone in th

261 al analyses revealed that moderate-to-severe knee pain was associated with percent denuded bone in th

262 Moderate-to-severe knee pain was defined as a score of >or=40 mm on a knee-

263 fic 100-mm visual analog scale, and frequent knee pain was defined as pain on most days during the pa

264 d isometrically for each leg separately, and knee pain was evaluated by questionnaire.

265 Knee pain was evaluated using a visual analog scale scor

266 fusion to frequent knee pain and severity of knee pain was examined using conditional logistic regres

267 Knee pain was measured with the pain subscale of the Wes

268 tomatic knee OA was recorded as present when knee pain was reported and the symptomatic knee had radi

269 Frequent knee pain was reported in 24.1% of women assigned to rec

270 in the temporal fluctuation of self-reported knee pain was seen in this community-based prospective s

271 ren-Lawrence score from radiography, whereas knee pain was self-reported.

272 In conditional logistic analyses, knee pain was significantly associated with both radiogr

273 Baseline knee pain was slightly worse in the treatment group (mea

274 frequent knee pain) on most days; absence of knee pain was the baseline eligibility criterion.

275 e (the more symptomatic one in subjects with knee pain) was imaged with a 1.5T scanner using T1- and

276 c visits, the odds ratios (ORs) for frequent knee pain were 1.2, 1.2, 1.5, 2.2, 2.4, and 2.5, respect

277 ears), prevalences of knee OA and persistent knee pain were 11% and 30%, respectively.

278 Participants in this substudy on knee pain were 969 postmenopausal women, with a mean age

279 erity of knee pain and disability related to knee pain were determined using the Western Ontario and

280 ported that they currently had either hip or knee pain were recruited from the UK Somerset and Avon S

281 atellar taping or bracing effects on chronic knee pain were sourced from 7 electronic databases (to N

282 (282 patients aged >/=50 years with chronic knee pain) were treated by family physician acupuncturis

283 cts ages 45 years and older, with or without knee pain, were recruited from Veterans Affairs medical

284 the observed heterogeneity of self-reported knee pain when pain status is measured at only one time

285 The primary efficacy measures were knee pain while walking and the patient's global assessm

286 ugh 16, the mean reductions from baseline in knee pain while walking ranged from 45 to 62% with vario

287 of people with and those without knee OA and knee pain who meet recommended physical activity levels

288 individuals ages 70-79 years with unilateral knee pain who were enrolled in the Health, Aging, and Bo

289 nty-five films from individuals with chronic knee pain who were not awaiting TKR and 75 films from as

290 in 9% of films from individuals with chronic knee pain who were not awaiting TKR, and in 1% of films

291 s were men and women (ages 70-79 years) with knee pain who were participating in the Health, Aging, a

292 cordance, as well as between fluctuations of knee pain with changes in specific structural lesions.

293 We examined the association of knee OA and knee pain with fracture and falls in elderly men and wom

294 sponders were categorized as having no pain, knee pain with or without pain elsewhere, or other pain

295 lso assessed were whether patients discussed knee pain with their primary care provider or saw an ort

296 f words uttered by participants experiencing knee pain with words used by participants experiencing h

297 ed an underlying biomedical model of care of knee pain, with knee OA viewed as a progressive degenera

298 Arthritic Knee Pain through Exercise [ESCAPE-knee pain]) with usual primary care in improving functio

299 olving 695 adults ages >/=50 years reporting knee pain within the last year identified by postal surv

300 th 3 general practices and were experiencing knee pain within the previous 6 months attended research