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1 ha into injured nerves in the TNF-alpha gene knock-out mouse.
2 lls, we established a T-cell-specific S1P(1) knock-out mouse.
3 bly of receptor subunits, we studied a GluR2 knock-out mouse.
4 ons in locomotion and pain perception in the knock-out mouse.
5 d by the unique phenotypes for each TGF-beta knock-out mouse.
6 tibody against MT1-MMP, raised in an MT1-MMP knock-out mouse.
7 ophrenia, the forebrain-specific calcineurin knock-out mouse.
8 is occluded in neurons generated from PICK1 knock-out mouse.
9 educed in a phospholipase C beta1 (PLCbeta1) knock-out mouse.
10 ly spliced CFTR mRNA is produced in this CF 'knock-out' mouse.
14 erated an intestinal epithelium-specific Raf knock-out mouse and identified Raf kinase as a key regul
15 ology, we used Sp1 siRNA, a heterozygous Sp1 knock-out mouse, and mithramycin A, a DNA-intercalating
18 CaR was increased in lysates from GABA-B-R1 knock-out mouse brains and in cultured hippocampal neuro
19 c-8b in vivo, we generated a tissue specific knock-out mouse by crossing OMP-Cre transgenic mice to R
21 nthesis was markedly attenuated in the LOX-1 knock-out mouse cardiac fibroblasts as well as in WT mou
22 as overexpressed in wild-type (WT) and LOX-1 knock-out mouse cardiac fibroblasts by transfection with
27 vents that were attenuated in the caveolin-1 knock-out mouse confirming a role for CEMs in ROS genera
28 ong-term depression occurred in the mGluR(4) knock-out mouse, consistent with its postsynaptic origin
29 2AX was markedly suppressed in the Plk3(-/-) knock-out mouse corneal epithelial layer in response to
31 and the visual blind cone-rod homeobox gene knock out mouse (Crx(-/-) ) with degeneration of the ret
36 inhibited proliferation in both LKB and LKB knock-out mouse embryo fibroblasts to similar extent and
38 apoptosis induction in Akt1 and Akt2 double knock-out mouse embryonic fibroblast cells (MEF-Akt1,2-D
39 VDAC3 knock-out but not VDAC1 and -3 double knock-out mouse embryonic fibroblast cells, confirming t
40 hat when compared with wild-type cells, PTEN knock-out mouse embryonic fibroblasts (PTEN KO MEF) have
42 r77 transfection into RXRalpha wild-type and knock-out mouse embryonic fibroblasts and subsequent tre
46 ctional connections, we found by using STAT3 knock-out mouse embryonic fibroblasts that RhoA, Rac1, a
47 l responses are enhanced in Spry1,2,4 triple knock-out mouse embryonic fibroblasts, consistent with n
48 ased using small interfering RNA and in Msk1 knock-out mouse embryonic fibroblasts, suggesting that t
52 cardiomyocytes cultured from homozygous jmj knock-out mouse embryos (jmj mutants) show increased cel
54 n the cerebral wall of the dopamine receptor knock-out mouse embryos further confirmed the effects of
57 ectroporated with FMRP small hairpin RNA and knock-out mouse embryos lacking FMRP reveals that specif
61 ation and myelination, we used a conditional knock-out mouse for voltage-operated Ca(2+) channels in
62 hermore, since production of a transgenic or knock-out mouse frequently requires cross-breeding, care
65 her characterize this region, we generated a knock-out mouse (GREKO(-/-)) with a deletion of the mGnR
69 amined its processing in PC2, 7B2, and PC1/3 knock-out mouse hypothalamic extracts and demonstrated t
70 onal activation in the wild-type (WT) and OT knock-out mouse in olfactory bulbs, piriform cortex, cor
71 ls in the forebrains of the Dlx1/Dlx2 double knock-out mouse in vivo Identification of Gad genes as d
72 n, we took advantage of a unique conditional knock-out mouse in which Lmx1b is genetically deleted in
73 ation, we generated an inducible conditional knock-out mouse in which the L-VGCC isoform Cav1.2 was d
74 pment, we generated an inducible conditional knock-out mouse in which the L-VOCC isoform Cav1.2 was p
75 dies, using a novel Casr intestinal-specific knock-out mouse, indicate that the genetic ablation of t
78 oss of collecting duct P2Y2 receptors in the knock-out mouse is the primary defect leading to increas
80 nced by interacting proteins, we generated a knock-out mouse lacking the HCN channel auxiliary subuni
81 hannels in the corpus cavernosum utilizing a knock-out mouse lacking the Slo gene (Slo-/-) responsibl
83 ential roles of PMP22, we engineered a novel knock-out (-/-) mouse line by replacing the first two co
84 rated an inducible, cell type-specific Ift88 knock-out mouse line (K5rtTA;tetOCre;Ift88(fl/fl)) to di
85 cultures, a postsynaptic density-95 (PSD-95) knock-out mouse line and electrophysiological analysis,
86 this study, we generated a conditional gene knock-out mouse line to specifically nullify Ggamma13 ex
87 We previously generated a conditional Pten knock-out mouse line with Pten loss in limited postmitot
88 c and excitatory neuron-specific conditional knock-out mouse line, and demonstrated that Dab1 is a cr
99 We developed and characterized a conditional knock-out mouse model and found that GSKIP deficiency ca
100 own to ameliorate mitochondrial disease in a knock-out mouse model lacking a nuclear-encoded gene spe
103 To address in vivo function, we generated a knock-out mouse model of G2E3 deficiency that incorporat
104 romotes "off-target" tumorigenesis in a MDR2 knock-out mouse model of hepatocellular carcinoma (HCC)
106 function of the NuRD complex, we generated a knock-out mouse model of the Mta2 (metastasis-associated
107 To overcome these issues, an acute Hnf4a knock-out mouse model was generated through use of the t
110 ell as in a neuron-specific Tsc1 conditional knock-out mouse model, and show differential responses t
111 rage in an in vivo constitutive adipose FIT2 knock-out mouse model, but the physiological effects of
112 JB6 deletion as well as in the previous Cx30 knock-out mouse model, defective Cx26 expression is the
121 es released from proteins of three different knock-out mouse models associated with O-mannosylation (
122 mmals by generating and using a range of new knock-out mouse models for the hypusine-modifying enzyme
124 : Due to the development of numerous genetic knock-out mouse models, the identification of specific r
129 that genetic inactivation of the 5-HTT in a knock-out mouse not only failed to prevent ethanol-induc
130 cific for ANGPTL4, recapitulated the Angptl4 knock-out (-/-) mouse phenotype of reduced serum TG leve
133 -dominant neural retina leucine zipper (Nrl) knock-out mouse retinas compared with wild type rod-domi
134 der excitotoxic condition, cell loss in Cx45 knock-out mouse retinas was similar to that seen in wild
138 d in control (C57BL/6) mice and two congenic knock-out mouse strains with deletions of either TRPV1 o
140 Pharmacological inhibition and conditional knock-out mouse studies showed that Presenilin 1 and Not
143 and in a brain-restricted alpha-dystroglycan knock-out mouse that is similar to that seen in patients
145 AMPA receptors, we have used the GluR2(-/-) knock out mouse to determine whether the expression of m
146 For this purpose, we generated a conditional knock-out mouse to address the functions of the NMDA-R i
152 c-selective ankyrin-G(-/-) mice (conditional knock-out mouse), we report that ankyrin-G targets Nav1.
154 ld(s)) mouse and the chemokine receptor CCR2 knock-out mouse, we report that macrophage accumulation
155 Using a new alphaII spectrin conditional knock-out mouse, we show that alphaII spectrin is requir
156 lasts derived from the NF-kappaB1 (p105/p50) knock-out mouse were used to demonstrate that p50 expres
157 rther examined the role of COX2 using a COX2-knock-out mouse where pFUS was unable to increase MSC tr
158 only, with a nitric oxide synthase 2 (NOS2) knock-out mouse, which develops no AD-like pathology.
159 man mutation, we generated a new conditional knock-out mouse with a brain-specific deletion of Adk (A
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