ライフサイエンスコーパス: knockout mouse

1 OB) in the brain of wild-type but not Sig-1R knockout mouse.

2 y were investigated in retinas of the Ndufs4 knockout mouse.

3 neonatal lethal argininosuccinate synthetase knockout mouse.

4 mechanisms causing XLRP, we generated an RP2 knockout mouse.

5 vo function of TRPML2, we generated a TRPML2-knockout mouse.

6 al development, we established a novel Egfl7 knockout mouse.

7 cute myeloid leukemia in the NR4A1 and NR4A3 knockout mouse.

8 ds of the transducin gamma-subunit (Ggamma1) knockout mouse.

9 ion of brain-specific Ank3 in a heterozygous knockout mouse.

10 a phenotype similar to that of the PKCdelta knockout mouse.

11 eration and characterisation of the first K7 knockout mouse.

12 es against that imaged in an inducible Rasa1 knockout mouse.

13 ransgenic mouse with a caspase-8 conditional knockout mouse.

14 ts of Andersen-Tawil Syndrome and the Kir2.1 knockout mouse.

15 al phenotype similar to that of the Atpbv1b1 knockout mouse.

16 the biological role of PHF20 by generating a knockout mouse.

17 ment in the low-density lipoprotein receptor knockout mouse.

18 lium using a conditional epithelium-specific knockout mouse.

19 vo as shown by ex vivo analysis of a NeuroD2 knockout mouse.

20 ns of TSPO, we first developed a viable TSPO knockout mouse.

21 ery low density lipoprotein receptor (Vldlr)-knockout mouse].

22 ate cortex between the serotonin transporter knockout mouse, a genetic animal model replicating featu

23 ftment and on liver repopulation in the mdr2-knockout mouse, a model for progressive familial intrahe

24 e use of a conditional, cardiac-specific G9a knockout mouse, a specific G9a inhibitor, and high-throu

25 Analysis of germline VGF-knockout mouse adrenal medulla revealed decreased LDCV s

26 and a conditional hepatocyte-specific AEG-1 knockout mouse (AEG-1(DeltaHEP) ).

27 ession in the urothelium of the female Foxa1 knockout mouse and an increase in the expression of a nu

28 Here, using the inducible Sel1L knockout mouse and cell models, we show that Sel1L is in

29 new B cell-specific PPARgamma (B-PPARgamma) knockout mouse and explored the role of PPARgamma during

30 Similarities between the HAS2 knockout mouse and the hdf mutant mouse, which has a mut

31 cleotide technology, the (platelet-specific) knockout mouse, and the transplantation of genetically m

32 e severe inflammatory response in AMPKalpha2 knockout mouse aortas, all of which were suppressed by c

33 ific inactivation of Inpp5b on a global Ocrl-knockout mouse background resulted in low molecular weig

34 al muscle similar to those seen in the Bmal1 knockout mouse (Bmal1(-/-) ), a model of advanced ageing

35 flammatory genes in WT but not in PLCepsilon knockout mouse brain.

36 e defect in secretory activation in the cSrc knockout mouse, but most importantly, the activity of cS

37 lly after depletion of OCT2 in a conditional knockout mouse, but their proliferation is reduced and i

38 ocytic function was only seen in septic PD-1 knockout mouse cells.

39 trial-specific Na(+) /Ca(2+) exchanger (NCX) knockout mouse, cellular Ca(2+) accumulation during spon

40 The International Knockout Mouse Consortium (IKMC) has produced a genome-w

41 The International Knockout Mouse Consortium (IKMC) introduces its targeted

42 ilding upon resources from the International Knockout Mouse Consortium (IKMC), we developed a targeti

43 ssue phenotype screen from the International Knockout Mouse Consortium and provides an open access re

44 However, the International Knockout Mouse Consortium uses an embryonic stem cell li

45 R assays were performed on wild-type and Pnn knockout mouse cornea.

46 reduced and patchy on IL-1 receptor (IL-1R)-knockout mouse corneas (P < 0.05, ANOVA).

47 e developed a new endothelium-specific DDAH1 knockout mouse (DDAH1(En-/-)) to investigate the signifi

48 A rod-specific Kif3/Kif17 double knockout mouse demonstrated that KIF17 and KIF3 do not a

49 ed in monocytes from WAS patients and in WAS-knockout mouse dendritic cells.

50 is corroborated by the existence of a Tenm4 knockout mouse displaying an ET phenotype, implicates TE

51 hat PB2 associates with mitochondria in MAVS knockout mouse embryo fibroblasts.

52 cell proliferation was also observed in Mfn2-knockout mouse embryonic fibroblast (MEF) cells as compa

53 We used an inducible Raptor and Rictor knockout mouse embryonic fibroblast (MEF) system to furt

54 om histone H3 K36 trimethyltransferase SETD2 knockout mouse embryonic fibroblasts (MEF) cells.

55 derived from affected individuals and Cdk10-knockout mouse embryonic fibroblasts (MEFs) proliferated

56 titers of infectious EBOV derived from SOCS3 knockout mouse embryonic fibroblasts (MEFs) were signifi

57 Using knockout mouse embryonic fibroblasts (MEFs), we demonstr

58 ction, we generated tamoxifen-inducible WASH-knockout mouse embryonic fibroblasts (WASHout MEFs).

59 Using knockout mouse embryonic fibroblasts and RGD peptide, we

60 diated depletion of Spartan from conditional knockout mouse embryonic fibroblasts results in impaired

61 the transcription factor EB (TFEB) in RagA/B knockout mouse embryonic fibroblasts, lysosomal acidific

62 Additionally, we show that in kindlin-2 knockout mouse embryonic fibroblasts, overactivation of

63 the genomic key feature of Tet1/Tet2 double-knockout mouse embryonic fibroblasts.

64 hibitor (EX-527) delayed cyst growth in Pkd1 knockout mouse embryonic kidneys, Pkd1 conditional knock

65 uced into otherwise microRNA-deficient Dgcr8 knockout mouse embryonic stem cells.

66 Geminin knockout mouse embryos are preimplantation lethal by the

67 We demonstrate that conditional knockout mouse embryos lacking Jun in Isl1-expressing pr

68 tions in MO-mediated gene knockdown frog and knockout mouse embryos unearthed PCP/CE-related phenotyp

69 In VDR knockout mouse epithelial cells (KO), 1,25(OH)2D3 increa

70 onstrate using isogenic pairs of conditional knockout mouse ESCs, that Snail1 exerts Wnt- and EMT ind

71 The discovery of a phenotype for the FGF1 knockout mouse establishes the PPARgamma-FGF1 axis as cr

72 Unlike the original knockout mouse, expression of Ki67, androgen receptor, a

73 in iPSC generation, yet, iPSC yield from AID-knockout mouse fibroblasts was similar to that of wild-t

74 ss this question by generating a conditional knockout mouse for Dpy30, which is a common core subunit

75 ion and remyelination, we used a conditional knockout mouse for VGCCs in OPCs.

76 alysis, Roxadustat rescued the hepatic HIF-1 knockout mouse from retinal oxygen toxicity, whereas DMO

77 ed with loss of REEP6 function using a Reep6 knockout mouse generated by CRISPR/Cas9 gene editing.

78 issue in a previously uncharacterised Hdac11 knockout mouse (Hdac11 (KO/KO)).

79 pression of catalase, in vivo, restored ATF6 knockout mouse heart function to wild-type levels in a m

80 wild-type and S-nitrosoglutathione reductase knockout mouse hearts (S-nitrosoglutathione reductase is

81 Conversely, Snrk knockout mouse hearts have increased glucose and palmita

82 Transcriptional profiling of Parkin knockout mouse hearts revealed compensatory upregulation

83 r nonstressed conditions, wild-type and ATF6 knockout mouse hearts were similar.

84 contrast with those in the embryonic-lethal knockout mouse, highlighting differences in redundancy i

85 and development by generating a conditional knockout mouse in which the protein is depleted from mus

86 of generic Wnt/beta-catenin targets in Rab8a knockout mouse intestinal crypts indicate reduced signal

87 here the gene of interest is essential and a knockout mouse is not available.

88 Even the reported phenotype of the J chain-knockout mouse is often misunderstood or underappreciate

89 s a protective genetic modifier in the Kcna1 knockout mouse (Kcna1-/-) model of SUDEP, while searchin

90 eoxyguanosine levels increased in both Aldh2-knockout mouse keratinocytes and ALDH2-knockdown human k

91 showed in cultured mammalian cells and Pkd1 knockout mouse kidney epithelial cells that PC1 and its

92 both intact wildtype and M2 or M1/3-receptor knockout mouse Langendorff hearts, atropine led to incre

93 A knockout mouse line (BC(-/-)) was generated and demonstr

94 e role of CRTC1 in the brain, we generated a knockout mouse line and analyzed its behavioral and mole

95 ral analysis of the resulting Nestin-Cre-Lpd knockout mouse line revealed a specific behavioural phen

96 e generated an inducible liver-specific Nrf1 knockout mouse line using animals harboring an Nrf1(flox

97 Using an inducible, EC-specific Panx1 knockout mouse line, we report a previously unidentified

98 Using a conditional knockout mouse line, we report that loss of pericytic la

99 Here, by utilizing a conditional knockout mouse line, we report that PDGFRbeta(+) cell-de

100 nerate and phenotypically characterize 5,000 knockout mouse lines, here we identify 410 lethal genes

101 we generated and analyzed three conditional knockout mouse lines, in which the essential PRC2 subuni

102 present evidence, in two different CK2alpha knockout mouse lines, that this regulation is region-spe

103 SUMOylation-deficient-Sf1(2KR/2KR) and Dax1 knockout mouse lines, with FAdE expression/activity reta

104 , plus cytochrome P450 oxidoreductase and b5 knockout mouse livers to validate P450 activation and es

105 We generated a liver-specific Repin1 knockout mouse (LRep1(-/-)) and systematically character

106 umulation and reduces tumorigenesis in Brca1-knockout mouse mammary epithelium.

107 the structural remodeling of the DCT in the knockout mouse may not be a direct consequence of aberra

108 now describe the generation of a second sAC knockout mouse model (C2KO) designed to more definitivel

109 tegy to generate the whole body dematin gene knockout mouse model (FLKO).

110 egated structures in the cerebellum of Mecp2 knockout mouse model (Mecp2 (-/y) ) during transition fr

111 and Myrcludex B binding in the first Slc10a1-knockout mouse model (Slc10a1 encodes NTCP).

112 perproliferation using an epidermal-specific knockout mouse model and found that CXCR4 limited kerati

113 specific for Rem2 was validated using a Rem2 knockout mouse model and used to show abundant expressio

114 fen-inducible and endothelial-specific Stat3 knockout mouse model by crossbreeding Stat3(floxed/KO) a

115 iction in an angiotensin-converting enzyme 2 knockout mouse model characterized by placental hypoxia.

116 Recently, we developed a knockout mouse model for the H3f3b gene, one of two gene

117 e-colony stimulating factor (G-CSF) receptor knockout mouse model in combination with bone marrow cel

118 The knockout mouse model in combination with sophisticated m

119 We generated a conditional Psip1 knockout mouse model in the hematopoietic compartment an

120 ndings are mirrored in a novel inducible p68 knockout mouse model in which p68 depletion results in a

121 eted disruption of Dot1l using a conditional knockout mouse model inhibited leukemogenesis mediated b

122 In a knockout mouse model of Alix, we identified overt struct

123 nanoparticles in vivo in an apolipoprotein E-knockout mouse model of atherosclerosis and show that th

124 Here we report the development of a unique knockout mouse model of CDKL5-related disorders and demo

125 than CDME, and 1b was effective in vivo in a knockout mouse model of cystinuria.

126 ogenesis, we created a biallelic conditional knockout mouse model of GRP78 and PTEN in the hematopoie

127 iorate disease pathology in a laminin-alpha2 knockout mouse model of muscular dystrophy, acting as a

128 1 is elevated in the cortex in the Nrg1(+/-) knockout mouse model of schizophrenia (SZ).

129 A knockout mouse model of SIRT6 has displayed dramatic phe

130 Here, we describe a complete knockout mouse model of the autism-associated Shank3 gen

131 We report here that the Ptrh2 knockout mouse model recapitulates the progressive conge

132 Study of an available knockout mouse model showed that the mutant mice display

133 The Slc10a1-knockout mouse model supports the central role of NTCP i

134 Here we generated a conditional knockout mouse model that acutely deletes Grp78 in the a

135 In this study, we generated an AFAP1 knockout mouse model that establishes a novel physiologi

136 ng inflammaging, we used a Foxn1 conditional knockout mouse model that induces accelerated thymic inv

137 andidate gene was identified, we generated a knockout mouse model that manifested the phenotype and s

138 We now describe the Tmem67(tm1(Dgen/H)) knockout mouse model that recapitulates the brain phenot

139 viously generated an Ikbkap/Elp1 conditional-knockout mouse model that recapitulates the selective de

140 Here we established a Stra6 knockout mouse model to analyze the metabolic basis of v

141 ons experimentally, we generated a Bap1(+/-) knockout mouse model to assess its susceptibility to mes

142 e used a pan-DC, CD11c-specific cre-lox gene knockout mouse model to assess the role of KLF2 in DC ac

143 We used a knockout mouse model to functionally validate MMP10's ro

144 Using an inducible knockout mouse model to generate dynamin 1- and 2-defici

145 transducer and activator of transcription 3 knockout mouse model to investigate the effect of abroga

146 uman tissue and generated a cardiac-specific knockout mouse model to investigate the functional impac

147 muscle function, we developed a conditional knockout mouse model to specifically delete Rbfox1 in ad

148 Here we have generated a conditional-knockout mouse model to study the functions of Cdk1 in v

149 Here, we have used an Hhex inducible knockout mouse model to study the role of Hhex in adult

150 We developed an Mrkn2 knockout mouse model to study the role of this gene, and

151 We used an inducible beta-cell knockout mouse model to test the hypothesis that Sox4 is

152 We generated a miR-193b knockout mouse model to unravel the physiological functi

153 ss EAC development, we created a conditional knockout mouse model using progesterone receptor-Cre-rec

154 We used skeletal muscle-specific Cpt1b knockout mouse model where the inhibition of mitochondri

155 The existence of a conditional-Mylk-knockout mouse model with severe gut dysmotility and abn

156 e role of GDH using a beta-cell-specific GDH knockout mouse model, called betaGlud1(-/-).

157 vivo functions in the retina, we generated a knockout mouse model, designated "miR-183C(GT/GT)," usin

158 Using a knockout mouse model, radiotelemetry, and pharmacologica

159 nd skeletal anomalies in a heterozygous Bmp2-knockout mouse model, suggesting that haploinsufficiency

160 Finally, using an Itgb3 knockout mouse model, we confirmed that Itgb3 is dispens

161 Furthermore, through the use of a knockout mouse model, we demonstrate for the first time

162 Using a knockout mouse model, we demonstrate that loss of microR

163 With the use of a conditional knockout mouse model, we demonstrate that NF-Ya deletion

164 Using a gene-knockout mouse model, we demonstrate that the administra

165 scle-specific ring finger protein-1 (MuRF-1) knockout mouse model, we evaluated the role of the ubiqu

166 Through the generation of a knockout mouse model, we found that regression of the se

167 rthermore, by generating a TC10/Cdc42 double knockout mouse model, we found that TC10 can compensate

168 Thus, using a new knockout mouse model, we have identified Hic-5 expressio

169 Using a knockout mouse model, we now test this hypothesis direct

170 Using a mammary gland specific knockout mouse model, we show that Agr2 facilitates norm

171 Using a Cks2(-/-) knockout mouse model, we show that CKS2 counteracts CKS1

172 Using a T cell-specific conditional Id2 knockout mouse model, we show that inhibitor of DNA bind

173 By using a RhoA conditional knockout mouse model, we show that RhoA deficiency cause

174 Using a Ccm1 knockout mouse model, we studied the morphogenesis of ea

175 We have developed a double knockout mouse model, which also shows reduced muscle st

176 A conditional Neb knockout mouse model, which recapitulates thin filament

177 the pathogenesis of KIN, we generated a Fan1 knockout mouse model, with abrogation of Fan1 expression

178 ent, we studied a previously generated Abcd3 knockout mouse model.

179 y was significantly upregulated in the Olfm4-knockout mouse model.

180 generated and analyzed a conditional C9orf72 knockout mouse model.

181 screen on an inducible podocyte-specific WT1 knockout mouse model.

182 een shown to cause a severe hepatopathy in a knockout mouse model.

183 nerated and thoroughly characterized a Pdzd7 knockout mouse model.

184 RNA-p21 function, we generated a conditional knockout mouse model.

185 by utilizing a photoreceptor-specific, PKM2 knockout mouse model.

186 in tumorigenesis using a conditional genetic knockout mouse model.

187 of p14 in mouse DCs/LCs using a conditional knockout mouse model.

188 therefore sought to test this concept with a knockout mouse model.

189 erview of studies that have employed the sEH knockout mouse model.

190 stigated the role of CD63 in MC using a CD63 knockout mouse model.

191 cell development by generating a conditional knockout mouse model.

192 sive dystrophic epidermolysis bullosa (RDEB) knockout mouse model.

193 es from PKP2 heterozygous and DP conditional knockout mouse models also exhibit elevated TGF-beta1/p3

194 rated tissue-specific Ugt1 locus conditional knockout mouse models and examined the role of glucuroni

195 te of TA proteins in two tissue-specific WRB knockout mouse models and found that their dependence on

196 Conventionally, transgenic or knockout mouse models are used for this purpose.

197 as9-based genome editing can easily generate knockout mouse models by disrupting the gene sequence, b

198 In knockout mouse models for estrogen receptor or aromatase

199 Knockout mouse models for HDACs 1-9 have been important

200 The recent use of Ifit knockout mouse models has revealed novel antiviral funct

201 anulosa cell-specific androgen-receptor (AR) knockout mouse models have been used to show that androg

202 Amtn overexpression and Amtn knockout mouse models have defective enamel with no othe

203 Conditional knockout mouse models have revealed tissue specific requ

204 Recent studies using conditional knockout mouse models have unveiled a major role for HIF

205 function of S1P, we generated brain-specific knockout mouse models in which S1P-lyase (SPL), the enzy

206 Furthermore, neonatal and interferon gamma knockout mouse models of C. parvum infection identified

207 and human APOBEC3 proteins in transgenic and knockout mouse models of viral infection suggest that th

208 Our study using knockout mouse models provides convincing genetic eviden

209 However, studies of Mst1/2 knockout mouse models revealed that the identity of the

210 Studies in knockout mouse models showed that intestinal beta-carote

211 Knockout mouse models suggest that OSR1 mainly activates

212 We use conditional Numb- and Numbl-knockout mouse models to demonstrate that loss of Numb/N

213 We take advantage of ACV and ACVI knockout mouse models to test the hypothesis that there

214 Using uroplakin knockout mouse models we show that cell compliance is co

215 r development, we created two liver-specific knockout mouse models with the deletion of Grp94 alone,

216 T1 knockdown in breast cancer cell lines and knockout mouse models, suggest the potential involvement

217 been extensively studied in tissue-specific knockout mouse models, the systemic role of SIRT1 is sti

218 ragm and soleus muscles of the knockdown and knockout mouse models, we demonstrated that ssTnT defici

219 Using 2 fibroblast-specific GSK-3beta knockout mouse models, we show that deletion of GSK-3bet

220 SRSF2 in hematopoiesis by using conditional knockout mouse models.

221 t through global and cardiac specific tbeta4-knockout mouse models.

222 t5a(-/-) and Nestin-Cre mediated conditional knockout mouse models.

223 both early- and later-stage Pkd1 conditional knockout mouse models.

224 were required as inferred from studies using knockout mouse models.

225 d data from three independently-derived dlg1-knockout mouse models; two germline deficient knockouts

226 This effect persisted in FFAR2/3-knockout mouse monocytes and was not reproduced by synth

227 Here we analyse skin from 538 knockout mouse mutants generated by the Sanger Institute

228 sing an N-cadherin lens-specific conditional knockout mouse, N-cad(Deltalens), show that loss of this

229 ng a conditional nociceptor-specific NaV 1.7 knockout mouse (NaV 1.7(Nav1.8) ) and selective small-mo

230 JIP3 knockout mouse neuron primary cultures accumulate lysoso

231 lecular substitution of human PTEN into Pten knockout mouse neurons and assessed neuronal morphology

232 Finally, using syt-IV knockout mouse neurons, we found that syt-IV is necessar

233 We bred an Adamts7 whole-body knockout mouse onto both the Ldlr and Apoe knockout hype

234 We generated an M-opsin knockout mouse (Opn1mw (-/-)) expressing only S-opsin as

235 ated an inducible type II cell-specific p120-knockout mouse (p120EKO).

236 A Ccnd3 knockout mouse phenocopies these erythroid phenotypes, w

237 Interrogation of knockout mouse phenotype resources provides a further av

238 Our approach (from knockout mouse phenotype to human disease) demonstrates

239 haematological cancer somatic mutations and knockout mouse phenotypes--to identify 98 biological can

240 orter gene (lacZ) in the vector used for the Knockout Mouse Project (KOMP) is driven by the endogenou

241 a careful dental phenotyping in large-scale knockout mouse projects.

242 EAF2 knockout mouse prostate was also sensitized to gamma-irr

243 Furthermore, studies of the P-gp knockout mouse provided evidence that efflux transporter

244 Conversely, deletion of ASIC3 in the knockout mouse reduced pH sensitivity while the relative

245 racellular ionic permeabilities in the Ildr1 knockout mouse renal tubules are not affected.

246 of cystinosis are limited, with only a Ctns knockout mouse reported, showing cystine accumulation an

247 f the patient's serum to wild-type and TRPM1 knockout mouse retina revealed strongly labeled bipolar

248 Rbfox1 gene to autism, and a brain-specific knockout mouse revealed a critical role for this splicin

249 ockdown of H19 RNA in myoblast cells and H19 knockout mouse satellite cells decreases differentiation

250 Furthermore, when CRP knockout mouse serum was replenished with CRP, there was

251 The Reep1 knockout mouse should be a very useful model in which to

252 ucer and activator of transcription (STAT)-1 knockout mouse showed that IFN-gamma signaling in kerati

253 ly expressed throughout the brain, the CLC-3 knockout mouse shows complete, selective postnatal neuro

254 ted at the transcriptional level in loricrin knockout mouse skin and confirm that late cornified enve

255 Here, we developed a brain-specific Slc6a8 knockout mouse (Slc6a8-/y) as an animal model of human C

256 By generating a beta-cell-specific Mcl-1 knockout mouse strain (betaMcl-1KO), we observed that, s

257 ulation of NCC in vivo, we used a total WNK4-knockout mouse strain (WNK4(-/-)).

258 Herein we characterized a MIM knockout mouse strain and observed that MIM-deficient mi

259 in EH in vivo we developed a new functional knockout mouse strain by deleting the pore domain of TRP

260 GC B cells by crossing the Gna13 conditional knockout mouse strain with the GC-specific AID-Cre trans

261 Using two conditional knockout mouse strains and derived cells, we demonstrate

262 se conclusions using platelets from syntaxin-knockout mouse strains and from a Familial Hemophagocyti

263 therapy for glioma, we used a combination of knockout mouse strains and specific immunocyte ablation

264 scriptomes and targeted metabolomics of five knockout mouse strains deficient in essential factors re

265 hose goal is to produce and phenotype 20,000 knockout mouse strains in a reproducible manner across t

266 e in LP-BM5-infected wild-type (w.t.) versus knockout mouse strains that are differentially susceptib

267 In this study, we generated 2 knockout mouse strains that lacked pKal and HK and deter

268 n different BALB/c and C57BL/6 wild-type and knockout mouse strains, and immune profiling was carried

269 talog of gene function by characterizing new knockout-mouse strains across diverse biological systems

270 Although FOXC1 knockout mouse studies showed that it is not required fo

271 or the synaptic vesicle protein SV2a using a knockout mouse system.

272 sly, we generated and characterized a Trim32 knockout mouse (T32KO) that displays both neurogenic and

273 Here, we describe a Crb3 knockout mouse that demonstrates extensive defects in ep

274 e creatine kinase (MCK) conditional frataxin knockout mouse that mirrors the disease have demonstrate

275 We demonstrate with a Prps2 knockout mouse that the nexus between protein and nucleo

276 the Lewis lung carcinoma (D122) in the NCR1 knockout mouse that was generated by our group, in vario

277 he method for C57BL/6J (wild-type) and PP2Cm knockout mouse tissues, including kidney, adipose tissue

278 We generated an Mmp1a knockout mouse to ascertain whether stromal-derived Mmp1

279 proteins bind necrotic cells, we generated a knockout mouse to assess the role of Treml4 in the uptak

280 omyocyte-specific, tamoxifen-activated, PKP2 knockout mouse to demonstrate that in addition to its ro

281 We used a superoxide dismutase knockout mouse to demonstrate that oxidative stress dire

282 ailed to dilate the arteries from the KCNMB1 knockout mouse, underscoring BK beta1's role in HENA act

283 ated in brain tissue from an HGprt-deficient knockout mouse using immunoblots, and in a cell model of

284 We also created an adipose Grp78-knockout mouse utilizing the aP2 (fatty acid binding pro

285 In this study, a knockout mouse was created that abolished LIMK2 biochemi

286 on of SM-depleted platelets from SM synthase knockout mouse was delayed significantly, suggesting tha

287 In this study, the p53 knockout mouse was employed as a model to study the muta

288 Here, a CR-C knockout mouse was established to determine its role on

289 A conditional TSPO knockout mouse was generated by utilizing the Cre-Lox sy

290 ese variants, we took advantage of the Usp9x knockout mouse we generated.

291 last lines derived from an Arpc2 conditional knockout mouse, we established matched-pair cells with a

292 In the Fmr1 knockout mouse, we find a delay in somatosensory map for

293 Based on the P2X(7) knockout mouse, we hypothesized that children with low P

294 Here, making use of a newly generated Pdgfd knockout mouse, we reveal a functionally important malig

295 Using an isoform-specific knockout mouse, we show that hair cells expressing only

296 us infection, memory CD8 T cells in the CR-C knockout mouse were formed in greater numbers, were more

297 re we present a novel Mks1(tm1a(EUCOMM)Wtsi) knockout mouse which accurately recapitulates the human

298 Here, we describe an Atp6v0a4 knockout mouse, which lacks the a4 subunit.

299 In contrast to the reported phenotype of the knockout mouse, which was developed on a primarily C57BL

300 ering to develop a SPAR-polypeptide-specific knockout mouse while maintaining expression of the host