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1 the mammalian intestinal epithelium were not known.
2 the genome is organized and delivered is not known.
3 elated donor (URD), and methotrexate are not known.
4 ying mechanisms and functional roles are not known.
5 egative (HIV-) brain-dead donor (BDD) is not known.
6 nisms underlying this increased risk are not known.
7 CF, and TERRA in telomere replication is not known.
8 tomography criteria have mild disease is not known.
9 nts may influence one another is only partly known.
10 duce a panoply of antimicrobial peptides now known.
11 coordinated through a single receptor is not known.
12 ese different activities are mediated is not known.
13 ruitment and effector differentiation is not known.
14 ng simulated data when the ground truths are known.
15 emia, is one of the most infectious bacteria known.
16  molecular pathomechanisms are not precisely known.
17 ver, the mechanistic role of EEA1 is not yet known.
18                         Relatively little is known about changes in bee community composition in the
19 opsis (Arabidopsis thaliana), very little is known about floral induction in tulip.
20                               Very little is known about how archaeal cells orchestrate transcription
21  causes beta-cell dysfunction, but little is known about how cells handle excess fuels to avoid toxic
22                           However, little is known about how cells sense and respond to mechanical co
23                                    Little is known about how donor factors, timing of procurement, an
24                           However, little is known about how genes are specifically affected by early
25                                    Little is known about how genetic variation and epigenetic marks i
26              However, surprisingly little is known about how LMP1 expression is regulated in epitheli
27 y of protein-encoding transcripts, little is known about how miRNAs themselves are degraded.
28                           However, little is known about how the activity of these proteins is regula
29  neurotransmitters, but relatively little is known about how they are formed.
30 fferent fatty acids; however, very little is known about how zDHHC enzymes contribute to acyl chain h
31 educe mortality or hospitalizations, less is known about its effect on health status.
32 ery is conserved between kingdoms, little is known about its evolution.
33  demonstrated its high prevalence, little is known about its potential consequences on visual functio
34 lling of target cells; however, much less is known about its role in NK cells.
35 y of anion channels in plants, but little is known about most of its members.
36                                    Little is known about placental vitamin D metabolism and its impac
37 gulating harmful algal blooms, but little is known about the biochemical and physiological changes as
38  been characterized biochemically, little is known about the biology of amyloidogenic plasma cells (P
39 l on the timescale of seconds, and little is known about the downstream effects from this modulation.
40 lyst activity and selectivity, yet little is known about the dynamic compositional and structural cha
41                                    Little is known about the function of the cholinergic efferents in
42                                    Little is known about the functional development of individual neu
43                             Although much is known about the hydraulics of xylem, the hydraulic inter
44                                    Little is known about the impact of another testing strategy, rout
45 biology to computer science, still little is known about the impact of environmental changes on an ar
46                         Relatively little is known about the in vivo functions of newly emerging gene
47 y a role in viral persistence, but little is known about the kinetics of the generation, the tissue d
48                           However, little is known about the mechanism(s) by which this feedback occu
49 e under conditions of hypoxia, but little is known about the mediators of this effect.
50 associated with preterm birth, but little is known about the microglial response in preterm infants.
51                           However, little is known about the molecular and cellular determinants in m
52 nitiators of immune responses, but little is known about the molecular pathways used by DCs to sense
53 rast to a wealth of human studies, little is known about the ontogeny and consistency of empathy-rela
54 r clean energy via hydropower, but little is known about the potential impact of dam-building on the
55                         Virtually nothing is known about the relevance of glycolysis in patients with
56  essential for normal development, little is known about the specific functions of the different MLL
57                           However, little is known about the specific relationship between asthma and
58 nately of the protein Ribeye, very little is known about the structural dynamics of ribbons.
59 lity in HFpEF is sudden death, but little is known about the underlying mechanisms.
60                             Although much is known about the underlying signaling pathways, it remain
61  tumor antigen-specific T cells, but less is known about their effects on natural killer (NK) cells,
62 haracterized in model organisms, but less is known about these basic aspects of cell biology in early
63 any learning and memory processes, little is known about these properties specifically on cue-activat
64                                    Little is known about these small RNAs in litchi (Litchi chinensis
65 equilibrium is well understood, much less is known about tipping of oscillations (limit cycles) thoug
66                           However, little is known about whether and how long-range cross-frequency c
67 repair and healing after ischemia, little is known about whether T cells directly impact cardiac fibr
68  peptides with DPP-IV inhibitory features or known activity were identified by liquid chromatography-
69 ude amyloidogenic peptides, such as the well-known amyloid-beta peptide involved in Alzheimer's disea
70 oduced several simple models inspired by the known anatomical structures and neuronal responses withi
71                     In summary, we validated known and identified additional determinants for wrinkli
72 equences promises unbiased identification of known and novel microbes.
73                   The expression patterns of known and putative SSP genes based on 144 RNA sequencing
74            Lutein is a carotenoid presenting known anti-inflammatory and antioxidant properties.
75 D is an environmental and dietary agent with known anticarcinogenic effects, but protection against b
76 aco, one of the sources of the ancient resin known as "dragon's blood".
77         The glomerular filtration barrier is known as a 'size cutoff' slit, which retains nanoparticl
78 ly visual cortex results in a visual percept known as a phosphene.
79 alues for a family of 16 literature ligands, known as bpp(X,Y) [X,Y-substituted 2,6-(pyrazol-1-yl)pyr
80 IP2 (TRAF3 Interacting Protein 2; previously known as CIKS or Act1) is an oxidative stress-responsive
81 thetic-biology approach based on a technique known as codon shuffling.
82 hey possess shorter superposition lifetimes, known as coherence times or T2, due to interactions with
83 requently experience clinical deterioration, known as cryptococcosis-associated immune reconstitution
84 d proteins, binds specifically to GODZ (also known as DHHC3), a cellular Golgi apparatus-specific Asp
85 a), but can develop uncontrollable movements known as dyskinesia upon treatment with L-DOPA.
86   The alpha-helical region of separase (also known as Esp1) contains four domains (I-IV), and a subst
87 s can be beneficial for health and survival, known as hormesis.
88                         Freeze casting, also known as ice-templating, is a technique that has receive
89           The leukocyte integrin Mac-1 (also known as integrin alphaMbeta2, or CD11b/CD18) is crucial
90                                 IRAK-M, also known as IRAK-3, is an inhibitor of proinflammatory cyto
91 ly up-regulated mammalian lncRNA, FOXD3-AS1, known as linc1623 in mice, in the setting of hyperoxia/r
92 oles for bacterially derived vitamin K forms known as menaquinones in health and disease, which may b
93    K(lysine) acetyltransferase 8 (KAT8, also known as MOF) mediates the acetylation of histone H4 at
94 sor factor RE1-silencing transcription (also known as neuron-restrictive silencer factor) to position
95 lves a multivariate resolution curve fitting known as non-negative matrix factorization with alternat
96 ng strand is replicated in discrete segments known as Okazaki fragments.
97 n added by ADP-ribosyltransferases, commonly known as PARPs, but it can also be added by other enzyme
98 he major surface antigen of the blood stages known as Pf EMP1 encoded by up to 60 var genes per genom
99 c amino acid phenylalanine (Phe) in animals, known as phenylketonuria, are mitigated by excretion of
100  protein tyrosine phosphatase (TC-PTP), also known as PTPN2, as a negative regulator of IL-7R-STAT si
101 tion of the organic-rich (sapropel) interval known as S5.
102 e black hole at the center of the Milky Way, known as Sagittarius A* (Sgr A*), may have affected the
103 t 50 years one such lineage of meningococci, known as serogroup A, clonal complex 5 (A:cc5), has caus
104 n in the scavenger receptor B1 (SCARB1; also known as SR-B1) gene.
105                              This phenotype, known as T cell exhaustion, occurs during chronic infect
106 ing neurodegenerative disorders collectively known as tauopathies.
107 festation by Myzus persicae Sulzer, commonly known as the green peach aphid (GPA), which is an import
108 can permeabilize tissue through a phenomenon known as transient cavitation, can be used to deliver RN
109 e HSV-1 virion protein 13/14 (VP13/14), also known as UL47, is a tegument antigen targeted by CD8(+)
110 uman cytomegalovirus signal-anchored protein known as viral mitochondria-localized inhibitor of apopt
111                  One of the Yops, YopO (also known as YpkA) obstructs phagocytosis through disrupting
112 ns of the recombination regulator Cst9 (also known as Zip3).
113 0A9 (solute carrier family 30 member 9; also known as ZnT-9) is ubiquitously expressed with high leve
114 We also identified several CNVs that include known ASD genes (SHANK3, CDH10, CSMD1) or genes involved
115 re transmitted via insect vectors, little is known at the molecular level as to how the viruses are r
116 lls with a natural disaccharide trehalose, a known autophagy enhancer, delays SG assembly and facilit
117  of states, clearly distinct from the widely known, bulk-like sigma- and pi-gaps.
118 at the use of two standards of CO2 in air of known but differing delta(13)C and delta(18)O isotopic c
119 reover, in contrast to their action on other known carbohydrates, both KCl and NaCl act as salting-ou
120 r, ubiquitin (Ub), regulates virtually every known cellular process in eukaryotes.
121 y smoking phenotype, we reconfirmed the well-known CHRNA5-CHRNA3-CHRNB4 genes and further yielded a n
122 ese CDMS measurements by using proteins with known collisional cross-sections for calibration.
123 erences in body composition in early life, a known contributor to obesity risk.
124 get identification and contact selection are known contributors to variability in efficacy across dif
125 uated DENV isolates.IMPORTANCE The lack of a known correlate of protection and the failure of a neutr
126               Human MSN modules recapitulate known cortical cytoarchitectonic divisions, and greater
127                                  Despite its known detrimental effects, iron deficiency remains the m
128  (FFPE) tissues and sterile body fluids with known diagnosis of IFD based on reference method results
129                        Surprisingly, despite known differences in the number of secretory cells in ge
130 o or stronger than the effects of other well-known drivers of productivity, including climate and nut
131                                   These well-known drug reservoirs can be used as smart carriers for
132                           Here we review the known ecological and evolutionary implications of symbio
133 imed replication origins connecting the long-known effect of genomic context on replication timing to
134 tes of phosphene perception closely resemble known electrophysiological correlates of conscious perce
135 hares some similarities to responses to well-known elicitors such as chitooligomers and OGs.
136 kella multacida (PhyAmm) in complex with the known eukaryotic second messengers Ins(1,3,4,5)P4 and In
137                                    It is not known exactly where amyloid-beta (Abeta) fibrils begin t
138                                           We know examples of such constraints, but we have no system
139       Understanding the relationship between known factors and spending increases over time could inf
140        Such a pressure induced transition is known for covalent liquids, but has not been observed fo
141 e existence of catalytic antibodies has been known for decades.
142                      The causative genes are known for fewer than 40% of PCLD index cases.
143                   RNA interference (RNAi) is known for its high catalytic activity and target selecti
144 bolites produced by brown seaweed, which are known for their nutraceutical and pharmacological proper
145 vocal detection of multiple chemical markers known for their use in the adulteration and counterfeiti
146  is confined to the nucleus, consistent with known functions of each of these two proteins.
147                          Unlike the other 14 known galectins in mammalian cells, which have dimeric o
148 ogenic variant p.Ala13Thr variant in MYL2, a known gene for HCM.
149 Mutations in LRRK2 represent the most common known genetic cause of PD.
150 , thus enabling the functional validation of known genetic risk factors and potentially pathogenic al
151 ed variants represent a tiny minority of all known genetic variation, and therefore there is necessar
152 he reactive intermediates are converted to a known genotoxic scaffold, providing metabolic support of
153 "- (for primed convertible) variants of most known green-to-red pcFPs.
154    Herbaspirillum rubrisubalbicans is a well-known growth-promoting rhizobacteria that can also act a
155                                     However, knowing how different species' metabolisms will integrat
156                            Participants with known hypertension in communities that had all four drug
157                                    It is not known if the other major types of pyramidal neurons in t
158 allergic contact dermatitis (ACD), it is not known if they are mediated by shared or distinct signali
159 ational age <32 weeks, birth weight <1000 g, known immunodeficiency or no Danish-speaking parent.
160 To compare the effects of both variants with known inactive GDP- and active GTP-bound RAB11B mutants,
161 st five years of life, often after the first known ingestion with typical rapid onset IgE-mediated sy
162 rface electrostatics with few, hitherto best known inhibitors of SOCE.
163               This method takes advantage of known interactions extracted from multiple sources such
164                                           No known iron complexes are considered photoluminescent at
165     We demonstrate JH receptor expression in known JH target tissues, in which temporal expression co
166 e details about the distribution of the well-known Lewis pairs, such as how they are distributed in s
167 cancer cells is questionable, given the well-known limitations of tumor-associated macrophages (TAMs)
168 gene mimicry is a striking phenomenon but we know little about the evolution of this trait in any spe
169 stump carcinoma is an exceptional and poorly known long-term complication after pancreaticoduodenecto
170  monoclonal antibodies (MAbs) that recognize known major antigenic sites in MeV-H, we identified a D4
171                                The currently known mechanisms for active forgetting include neurogene
172                           Here we found that known membrane insertion pathways fail to effectively en
173 r features (positive ion mode), including 70 known metabolites, in single dorsal and ventral cells in
174 mokers in two Swedish cohorts, differing for known MS risk factors.
175 e NRP1 cytoplasmic domain (NCD), but not the known NCD interactor GIPC1.
176 ctrolyte is demonstrated by modifying a well-known negative photoresist, SU-8, with LiClO4 .
177 otonin (5-hydroxytryptamine, 5-HT) is a well-known neurotransmitter that is involved in a growing num
178                          Any patient with no known ocular disease who desires a routine eye screening
179 eption of one inconclusive study, nothing is known of the genetic basis of this phenomenon.
180 saurus, Moabosaurus and Zby), was previously known only from the Jurassic of Europe.
181   Of the thousands of extrasolar planets now known, only six have been found that transit hot, A-type
182  photoconversion dynamics of Dendra2, a well-known PAFP used in localization microscopy.
183 y represents an estimated 20% of the world's known patients with Progeria.
184 one specimens from 20 exhumed individuals of known period of burial and age at death is described.
185 ppearance of neural maps, which we link to a known phase transition in an Ising-like model from stati
186 he receptor, which are indicated by its only known physiological ligand, podoplanin, being an integra
187 t skin pigmentation is highly heritable, but known pigmentation loci explain only a small fraction of
188                                    Nor is it known precisely how villus cell migration is affected wh
189                                     None are known previously for fossil odonatans.
190 6%) were in non-anticoagulated patients with known prior AF.
191 he abnormal aggregation of a small number of known proteins underlies the most common human neurodege
192       Components of e-cigarette aerosol have known pulmonary toxicity.
193 ing have been extensively studied, little is known regarding how tumor cell rolling on selectins faci
194  a published flea genome sequence, little is known regarding R. typhi biology in flea vectors that, i
195  older individuals, very little is currently known regarding regional changes in spontaneous BOLD sig
196                                     Wnts are known regulators of synapse formation, and our data reve
197          These findings, along with the well-known regulatory roles that SIRT1 plays in modulating bo
198 he most memory-efficient classical algorithm known requires infinite memory, while a quantum simulato
199 = 1) or ciprofloxacin (n = 1) in addition to known resistance determinants, collectively termed the "
200                       Among patients without known risk factors for iron deficiency, gastric acid inh
201                      For each helminthiasis, known risk factors, symptoms, and suggested options for
202 o highly conserved loop regions of uS12 with known roles in maintaining the accuracy of mRNA codon tr
203  proteome library from DIA data and to query known sequence variants.
204                                      Using a known series of triphenylamine-based dyes bearing haloge
205 al of A. baumannii in NHS, including already known serum resistance factors, and many novel genes not
206 autophosphorylated protein, we expand on the known set of CPK28 autophosphorylation sites, and we dem
207 d method to compare allele read fractions at known single-nucleotide polymorphisms, considering depth
208                              The most widely known solar geoengineering proposal is stratospheric aer
209 ion sites to protein-protein interactions of known structure and analysing the properties of the prot
210  the impact of AbetaOs in astrocytes, a less known subject.
211 atients with history of ASA sensitivity with known/suspected stable coronary artery disease or presen
212                      The second domain has a known SWIB/MDM2 fold, which was not observed before in o
213 erentiation of progenitors transduced with a known Tcra gene in the presence of antigen drives differ
214        We identify clusters corresponding to known tetraloop folds such as GGUG, RNYA, AGNN, and CUUG
215                                        We do know that human infants at birth show a preference to en
216                                           We know that this is largely ineffective with resistance ar
217                                  Conversely, knowing that there is unexplained residual phylogenetic
218                      Physiologists have long known that CO2 directly affects acid-base and ion regula
219                                  While it is known that ghrelin inhibits glucose-stimulated insulin s
220                               Although it is known that gross chromosomal abnormalities are remarkabl
221     As a countermeasure, numerous phages are known that produce proteins to block the function of cla
222                                              Knowing the rate and mechanisms of subsea permafrost deg
223 though the atomic structure of T4 is largely known, the dynamics of its fascinating injection machine
224 on uses the most structurally complex glycan known: the plant pectic polysaccharide rhamnogalacturona
225 race the sources of ambient particles and to know their potential impacts in human health and radiati
226 on and gold nanoparticles (Au-NPs) to induce known thermal decomposition reactions that cleave peptid
227 and well documented cases of island dwarfing known thus far took place over thousands of years.
228 ion and propensity score matching of factors known to affect recurrence to assess independent effects
229                 MicroRNAs (miRNAs) have been known to affect various biological processes by repressi
230  altered bodily sensations-both of which are known to be associated with insular functioning.
231             Traffic-related air pollution is known to be associated with skin aging manifestations.
232 le, expanding the arsenal of defence systems known to be at the disposal of prokaryotes against their
233 2A/B proteins form a coiled-coil interaction known to be critical for the formation of NuRD.
234 sphatidylcholine biosynthesis, that were not known to be essential for phototrophic growth.
235       TFIIH, whose recruitment to the PIC is known to be facilitated by the Mediator, then acts to re
236 eoperative temporal lobe white matter tracts known to be important in the generation and propagation
237  contains a hydrophobic triad W1L4L8 that is known to be important in the interaction with centrin.
238 tressor.Animals' response to acute stress is known to be influenced by sex and genetics.
239   (2) Single nucleotide polymorphisms (SNPs) known to be involved in human eye colour variation showe
240 gand stromal cell-derived factor (SDF)-1 are known to be involved in inflammation.
241 not induced, including at enhancers that are known to be repressed by a transcriptional repressor.
242 increases enzymatic activity of two key MMPs known to be secreted and activated in neuroinflammation,
243 tif, mutating it to CX4C ((182)CWAIAC(187)), known to block binding to CX3CR1, might decrease disease
244                        Optimizing a compound known to block the H3K27me3 site in EED discovered by in
245 ver that NAD(P)H oxidase 4 (NOX4), an enzyme known to catalyse the oxidation of NAD(P)H, is upregulat
246                                   Spinach is known to contain significant amounts of oxalates, which
247 lucocorticoid steroids, like prednisone, are known to delay loss of ambulation in patients with Duche
248 ed junctions of orthopaedic hip implants are known to differ and the debris generated varies in size,
249 tem, we first tested thiram, a DTC pesticide known to display neurotoxic effects, observing that it c
250  Mutants of the fusome, an organelle that is known to facilitate intracyst communication, compromise
251             Circularly polarized photons are known to generate a directional helicity-dependent photo
252 ns in the PBX homeobox 1 gene (PBX1), a gene known to have a crucial role in kidney development.
253  doping.Two-dimensional Dirac semimetals are known to host fermionic excitations which can mimic phys
254 tion (MIA) via infection during pregnancy is known to increase risk for autism spectrum disorder (ASD
255  temporal proximity to environmental impacts known to induce oxidative stress.
256 thene (TCE) by in situ minerals, and C2H2 is known to inhibit bacterial dechlorination.
257 id activation of cannabinoid (CB1) receptors known to inhibit presynaptic GABA release was significan
258 's sarcoma-associated herpesvirus (KSHV) are known to interact extensively with the DDR during the co
259                These regions contained genes known to interact with estradiol metabolism and cancer.
260                                  R-loops are known to interfere with replication forks, and sensitivi
261 et C-type lectin-like receptor 2 (CLEC-2) is known to maintain the physiological state of blood vascu
262  Tumor necrosis factor receptor 2 (TNFR2) is known to mediate immune suppression and tissue regenerat
263 ar to act in any of the three major pathways known to mend DNA DSBs, namely homologous recombination
264                        Lightning strikes are known to morphologically alter and chemically reduce geo
265 ent het-siRNAs also requires several factors known to participate in the effector portion of the RdDM
266 iotic usage toward antibiotics traditionally known to place patients at greater risk for CDI experien
267 -described activity-dependent mechanisms are known to play a key role in learning and memory.
268 e peptides isolated from natural sources are known to play important physiological roles in the human
269 m 2 is conserved between mouse and human and known to play key roles in neuronal function.
270      In general, clinicopathological factors known to predict and drive allograft fibrosis include gr
271 pression.SIGNIFICANCE STATEMENT Saccades are known to produce a suppression of contrast sensitivity a
272  Although proteasome-mediated proteolysis is known to produce antigenic peptides in adaptive immunity
273 ANG), a secreted vertebrate ribonuclease, is known to promote cell proliferation, leading to neovascu
274     BABY BOOM (BBM) genes in angiosperms are known to promote somatic embryogenesis, which like apoga
275                                 The pupil is known to reflect a range of psychological and physiologi
276 NCA following treatment with different drugs known to regulate alpha-SYN expression; while exogenous
277 rotein HYLS-1 is the only centriolar protein known to remain at the base of mature cilia and is requi
278                                        It is known to sense several stimuli that are potentially asso
279 tinct subtypes of inhibitory interneuron are known to shape diverse rhythmic activities in the cortex
280 ein, represents the first documented protein known to stimulate transforming growth factor (TGF)-beta
281                  Some microRNAs (miRNAs) are known to suppress breast cancer.
282  of 7,300-10,000 kelvin), and no planets are known to transit the even hotter B-type stars.
283  paradoxical because these steroids are also known to trigger muscle atrophy.
284 o-terminal domain with a fold distinct among known TRP structures, together with the carboxyl-termina
285 es that encode 80 genes, including novel and known virulence factors associated with adherence and au
286 ysis and genomic comparisons with previously known viruses.
287  a missing date of birth, diagnosis, or last known vital status.
288 transmitter for this biofilm response is not known, we find that addition of hydrogen sulfide gas to
289 support program recipients' self-efficacy in knowing what questions to ask their doctor significantly
290 he metabolic etiology of her lens changes is known, whereas the pathogenesis of ONHD is not clear.
291                                  However, to know whether these rescue mice maintain endogenous CB1 r
292 00 acetyltransferase activity, but it is not known whether CBP activity is controlled similarly.
293 crucibles for rapid evolution, but it is not known whether evolutionary changes arise mainly after su
294                           However, it is not known whether intravenous thrombolysis (IVT) is of added
295                       However, it is not yet known whether or how sensory stimulation might trigger a
296 se-associated factor 1 (Paf1), but it is not known whether TEFs have gene-specific functions.
297  and while it is highly conserved, it is not known whether the functional role of this splicing is al
298 stribution of pathogen-borne diseases and to know which pathogens actually cause fever.
299 icy preferences are private information, not known with certainty by the other politicians with whom
300 rprinting and linear combination analysis of known XANES reference compounds.

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