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1 the mammalian intestinal epithelium were not known.
2 the genome is organized and delivered is not known.
3 elated donor (URD), and methotrexate are not known.
4 ying mechanisms and functional roles are not known.
5 egative (HIV-) brain-dead donor (BDD) is not known.
6 nisms underlying this increased risk are not known.
7 CF, and TERRA in telomere replication is not known.
8 tomography criteria have mild disease is not known.
9 nts may influence one another is only partly known.
10 duce a panoply of antimicrobial peptides now known.
11 coordinated through a single receptor is not known.
12 ese different activities are mediated is not known.
13 ruitment and effector differentiation is not known.
14 ng simulated data when the ground truths are known.
15 emia, is one of the most infectious bacteria known.
16 molecular pathomechanisms are not precisely known.
17 ver, the mechanistic role of EEA1 is not yet known.
21 causes beta-cell dysfunction, but little is known about how cells handle excess fuels to avoid toxic
30 fferent fatty acids; however, very little is known about how zDHHC enzymes contribute to acyl chain h
33 demonstrated its high prevalence, little is known about its potential consequences on visual functio
37 gulating harmful algal blooms, but little is known about the biochemical and physiological changes as
38 been characterized biochemically, little is known about the biology of amyloidogenic plasma cells (P
39 l on the timescale of seconds, and little is known about the downstream effects from this modulation.
40 lyst activity and selectivity, yet little is known about the dynamic compositional and structural cha
45 biology to computer science, still little is known about the impact of environmental changes on an ar
47 y a role in viral persistence, but little is known about the kinetics of the generation, the tissue d
50 associated with preterm birth, but little is known about the microglial response in preterm infants.
52 nitiators of immune responses, but little is known about the molecular pathways used by DCs to sense
53 rast to a wealth of human studies, little is known about the ontogeny and consistency of empathy-rela
54 r clean energy via hydropower, but little is known about the potential impact of dam-building on the
56 essential for normal development, little is known about the specific functions of the different MLL
61 tumor antigen-specific T cells, but less is known about their effects on natural killer (NK) cells,
62 haracterized in model organisms, but less is known about these basic aspects of cell biology in early
63 any learning and memory processes, little is known about these properties specifically on cue-activat
65 equilibrium is well understood, much less is known about tipping of oscillations (limit cycles) thoug
67 repair and healing after ischemia, little is known about whether T cells directly impact cardiac fibr
68 peptides with DPP-IV inhibitory features or known activity were identified by liquid chromatography-
69 ude amyloidogenic peptides, such as the well-known amyloid-beta peptide involved in Alzheimer's disea
70 oduced several simple models inspired by the known anatomical structures and neuronal responses withi
75 D is an environmental and dietary agent with known anticarcinogenic effects, but protection against b
79 alues for a family of 16 literature ligands, known as bpp(X,Y) [X,Y-substituted 2,6-(pyrazol-1-yl)pyr
80 IP2 (TRAF3 Interacting Protein 2; previously known as CIKS or Act1) is an oxidative stress-responsive
82 hey possess shorter superposition lifetimes, known as coherence times or T2, due to interactions with
83 requently experience clinical deterioration, known as cryptococcosis-associated immune reconstitution
84 d proteins, binds specifically to GODZ (also known as DHHC3), a cellular Golgi apparatus-specific Asp
86 The alpha-helical region of separase (also known as Esp1) contains four domains (I-IV), and a subst
91 ly up-regulated mammalian lncRNA, FOXD3-AS1, known as linc1623 in mice, in the setting of hyperoxia/r
92 oles for bacterially derived vitamin K forms known as menaquinones in health and disease, which may b
93 K(lysine) acetyltransferase 8 (KAT8, also known as MOF) mediates the acetylation of histone H4 at
94 sor factor RE1-silencing transcription (also known as neuron-restrictive silencer factor) to position
95 lves a multivariate resolution curve fitting known as non-negative matrix factorization with alternat
97 n added by ADP-ribosyltransferases, commonly known as PARPs, but it can also be added by other enzyme
98 he major surface antigen of the blood stages known as Pf EMP1 encoded by up to 60 var genes per genom
99 c amino acid phenylalanine (Phe) in animals, known as phenylketonuria, are mitigated by excretion of
100 protein tyrosine phosphatase (TC-PTP), also known as PTPN2, as a negative regulator of IL-7R-STAT si
102 e black hole at the center of the Milky Way, known as Sagittarius A* (Sgr A*), may have affected the
103 t 50 years one such lineage of meningococci, known as serogroup A, clonal complex 5 (A:cc5), has caus
107 festation by Myzus persicae Sulzer, commonly known as the green peach aphid (GPA), which is an import
108 can permeabilize tissue through a phenomenon known as transient cavitation, can be used to deliver RN
109 e HSV-1 virion protein 13/14 (VP13/14), also known as UL47, is a tegument antigen targeted by CD8(+)
110 uman cytomegalovirus signal-anchored protein known as viral mitochondria-localized inhibitor of apopt
113 0A9 (solute carrier family 30 member 9; also known as ZnT-9) is ubiquitously expressed with high leve
114 We also identified several CNVs that include known ASD genes (SHANK3, CDH10, CSMD1) or genes involved
115 re transmitted via insect vectors, little is known at the molecular level as to how the viruses are r
116 lls with a natural disaccharide trehalose, a known autophagy enhancer, delays SG assembly and facilit
118 at the use of two standards of CO2 in air of known but differing delta(13)C and delta(18)O isotopic c
119 reover, in contrast to their action on other known carbohydrates, both KCl and NaCl act as salting-ou
121 y smoking phenotype, we reconfirmed the well-known CHRNA5-CHRNA3-CHRNB4 genes and further yielded a n
124 get identification and contact selection are known contributors to variability in efficacy across dif
125 uated DENV isolates.IMPORTANCE The lack of a known correlate of protection and the failure of a neutr
128 (FFPE) tissues and sterile body fluids with known diagnosis of IFD based on reference method results
130 o or stronger than the effects of other well-known drivers of productivity, including climate and nut
133 imed replication origins connecting the long-known effect of genomic context on replication timing to
134 tes of phosphene perception closely resemble known electrophysiological correlates of conscious perce
136 kella multacida (PhyAmm) in complex with the known eukaryotic second messengers Ins(1,3,4,5)P4 and In
144 bolites produced by brown seaweed, which are known for their nutraceutical and pharmacological proper
145 vocal detection of multiple chemical markers known for their use in the adulteration and counterfeiti
150 , thus enabling the functional validation of known genetic risk factors and potentially pathogenic al
151 ed variants represent a tiny minority of all known genetic variation, and therefore there is necessar
152 he reactive intermediates are converted to a known genotoxic scaffold, providing metabolic support of
154 Herbaspirillum rubrisubalbicans is a well-known growth-promoting rhizobacteria that can also act a
158 allergic contact dermatitis (ACD), it is not known if they are mediated by shared or distinct signali
159 ational age <32 weeks, birth weight <1000 g, known immunodeficiency or no Danish-speaking parent.
160 To compare the effects of both variants with known inactive GDP- and active GTP-bound RAB11B mutants,
161 st five years of life, often after the first known ingestion with typical rapid onset IgE-mediated sy
165 We demonstrate JH receptor expression in known JH target tissues, in which temporal expression co
166 e details about the distribution of the well-known Lewis pairs, such as how they are distributed in s
167 cancer cells is questionable, given the well-known limitations of tumor-associated macrophages (TAMs)
168 gene mimicry is a striking phenomenon but we know little about the evolution of this trait in any spe
169 stump carcinoma is an exceptional and poorly known long-term complication after pancreaticoduodenecto
170 monoclonal antibodies (MAbs) that recognize known major antigenic sites in MeV-H, we identified a D4
173 r features (positive ion mode), including 70 known metabolites, in single dorsal and ventral cells in
177 otonin (5-hydroxytryptamine, 5-HT) is a well-known neurotransmitter that is involved in a growing num
181 Of the thousands of extrasolar planets now known, only six have been found that transit hot, A-type
184 one specimens from 20 exhumed individuals of known period of burial and age at death is described.
185 ppearance of neural maps, which we link to a known phase transition in an Ising-like model from stati
186 he receptor, which are indicated by its only known physiological ligand, podoplanin, being an integra
187 t skin pigmentation is highly heritable, but known pigmentation loci explain only a small fraction of
191 he abnormal aggregation of a small number of known proteins underlies the most common human neurodege
193 ing have been extensively studied, little is known regarding how tumor cell rolling on selectins faci
194 a published flea genome sequence, little is known regarding R. typhi biology in flea vectors that, i
195 older individuals, very little is currently known regarding regional changes in spontaneous BOLD sig
198 he most memory-efficient classical algorithm known requires infinite memory, while a quantum simulato
199 = 1) or ciprofloxacin (n = 1) in addition to known resistance determinants, collectively termed the "
202 o highly conserved loop regions of uS12 with known roles in maintaining the accuracy of mRNA codon tr
205 al of A. baumannii in NHS, including already known serum resistance factors, and many novel genes not
206 autophosphorylated protein, we expand on the known set of CPK28 autophosphorylation sites, and we dem
207 d method to compare allele read fractions at known single-nucleotide polymorphisms, considering depth
209 ion sites to protein-protein interactions of known structure and analysing the properties of the prot
211 atients with history of ASA sensitivity with known/suspected stable coronary artery disease or presen
213 erentiation of progenitors transduced with a known Tcra gene in the presence of antigen drives differ
221 As a countermeasure, numerous phages are known that produce proteins to block the function of cla
223 though the atomic structure of T4 is largely known, the dynamics of its fascinating injection machine
224 on uses the most structurally complex glycan known: the plant pectic polysaccharide rhamnogalacturona
225 race the sources of ambient particles and to know their potential impacts in human health and radiati
226 on and gold nanoparticles (Au-NPs) to induce known thermal decomposition reactions that cleave peptid
228 ion and propensity score matching of factors known to affect recurrence to assess independent effects
232 le, expanding the arsenal of defence systems known to be at the disposal of prokaryotes against their
236 eoperative temporal lobe white matter tracts known to be important in the generation and propagation
237 contains a hydrophobic triad W1L4L8 that is known to be important in the interaction with centrin.
239 (2) Single nucleotide polymorphisms (SNPs) known to be involved in human eye colour variation showe
241 not induced, including at enhancers that are known to be repressed by a transcriptional repressor.
242 increases enzymatic activity of two key MMPs known to be secreted and activated in neuroinflammation,
243 tif, mutating it to CX4C ((182)CWAIAC(187)), known to block binding to CX3CR1, might decrease disease
245 ver that NAD(P)H oxidase 4 (NOX4), an enzyme known to catalyse the oxidation of NAD(P)H, is upregulat
247 lucocorticoid steroids, like prednisone, are known to delay loss of ambulation in patients with Duche
248 ed junctions of orthopaedic hip implants are known to differ and the debris generated varies in size,
249 tem, we first tested thiram, a DTC pesticide known to display neurotoxic effects, observing that it c
250 Mutants of the fusome, an organelle that is known to facilitate intracyst communication, compromise
252 ns in the PBX homeobox 1 gene (PBX1), a gene known to have a crucial role in kidney development.
253 doping.Two-dimensional Dirac semimetals are known to host fermionic excitations which can mimic phys
254 tion (MIA) via infection during pregnancy is known to increase risk for autism spectrum disorder (ASD
257 id activation of cannabinoid (CB1) receptors known to inhibit presynaptic GABA release was significan
258 's sarcoma-associated herpesvirus (KSHV) are known to interact extensively with the DDR during the co
261 et C-type lectin-like receptor 2 (CLEC-2) is known to maintain the physiological state of blood vascu
262 Tumor necrosis factor receptor 2 (TNFR2) is known to mediate immune suppression and tissue regenerat
263 ar to act in any of the three major pathways known to mend DNA DSBs, namely homologous recombination
265 ent het-siRNAs also requires several factors known to participate in the effector portion of the RdDM
266 iotic usage toward antibiotics traditionally known to place patients at greater risk for CDI experien
268 e peptides isolated from natural sources are known to play important physiological roles in the human
270 In general, clinicopathological factors known to predict and drive allograft fibrosis include gr
271 pression.SIGNIFICANCE STATEMENT Saccades are known to produce a suppression of contrast sensitivity a
272 Although proteasome-mediated proteolysis is known to produce antigenic peptides in adaptive immunity
273 ANG), a secreted vertebrate ribonuclease, is known to promote cell proliferation, leading to neovascu
274 BABY BOOM (BBM) genes in angiosperms are known to promote somatic embryogenesis, which like apoga
276 NCA following treatment with different drugs known to regulate alpha-SYN expression; while exogenous
277 rotein HYLS-1 is the only centriolar protein known to remain at the base of mature cilia and is requi
279 tinct subtypes of inhibitory interneuron are known to shape diverse rhythmic activities in the cortex
280 ein, represents the first documented protein known to stimulate transforming growth factor (TGF)-beta
284 o-terminal domain with a fold distinct among known TRP structures, together with the carboxyl-termina
285 es that encode 80 genes, including novel and known virulence factors associated with adherence and au
288 transmitter for this biofilm response is not known, we find that addition of hydrogen sulfide gas to
289 support program recipients' self-efficacy in knowing what questions to ask their doctor significantly
290 he metabolic etiology of her lens changes is known, whereas the pathogenesis of ONHD is not clear.
292 00 acetyltransferase activity, but it is not known whether CBP activity is controlled similarly.
293 crucibles for rapid evolution, but it is not known whether evolutionary changes arise mainly after su
297 and while it is highly conserved, it is not known whether the functional role of this splicing is al
299 icy preferences are private information, not known with certainty by the other politicians with whom
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