ライフサイエンスコーパス: knowledge

1 Cas9 in the archaeal domain of life, to our knowledge.

2 nternal predictions based on available prior knowledge.

3 the category-specific organization of object knowledge.

4 n, can cue a rich cascade of person-specific knowledge.

5 identify gaps between research and heuristic knowledge.

6 ble threat updating and explicit contingency knowledge.

7 vely expanded this curated map with database knowledge.

8 use of MGD in the advancement of scientific knowledge.

9 Results on real data agree well with current knowledge.

10 r bone metastasis treatment based on current knowledge.

11 To our knowledge, 20g and 23g represent the first achiral molec

12 To our knowledge, a new disorder-to-order transition is thus ob

13 Here we study, to our knowledge, a new model for medical device infection-that

14 context of protein folding, provides, to our knowledge, a new perspective on chromosome architecture.

15 Recently, we introduced, to our knowledge, a novel carotenoid carrier protein, COCP, whi

16 Here, we present, to our knowledge, a novel combination of 1) single-objective ba

17 Lack of knowledge about effective primary care nursing roles and

18 However, there is a lack of knowledge about fecal microbiome composition in several

19 has indicated higher level of awareness and knowledge about glaucoma in urban communities than previ

20 However, awareness and knowledge about glaucoma is unknown at community level,

21 , numerous studies have greatly expanded our knowledge about how microtubule organization and dynamic

22 The knowledge about lycopene's preventive effects in atheros

23 We have addressed the lack of knowledge about posttranscriptional contributions to noi

24 the methodology presented here can yield new knowledge about RTK interactions and can further our und

25 Most of our knowledge about stellar convection has come from studyin

26 BACKGROUND & AIMS: We have limited knowledge about the association between the composition

27 Knowledge about the causal relationship between objects

28 However, knowledge about the dynamics and the regulatory mechanis

29 worldwide will continue to provide critical knowledge about the factors that impact the natural hist

30 Our findings greatly increase knowledge about the geographic distribution and phylogen

31 ant disturbance to ecosystems worldwide, yet knowledge about the impacts of invasive species on bacte

32 e vaccines are in clinical trials, a lack of knowledge about the molecular basis that governs the ant

33 cosegregation of the variants and incomplete knowledge about the TBK1 functions relevant for neurodeg

34 adapt the infected cells to their needs, but knowledge about these transcriptional and post-transcrip

35 earning also facilitates the accumulation of knowledge across generations, helping people and artific

36 To our knowledge, ADPriboDB is the first publicly available dat

37 On top of the very large exchange of knowledge, all companies involved synergistically gained

38 Our results show for the first time, to our knowledge, an important role for CXCR3 and CXCL10 in the

39 We report for the first time, to our knowledge, an inverse association between hospital TAVR

40 However, despite the huge growth in knowledge and advances in prevention and treatment, ther

41 In this mini-review, we summarize current knowledge and experimental evidence for the potential of

42 s a substantial discrepancy between research knowledge and its clinical application.

43 aterials to improve healthcare providers' RI knowledge and practices throughout Nepal.

44 ons and gaps in scientific methodologies and knowledge and proposed and prioritized areas for future

45 f Physicians (ACP), including MKSAP (Medical Knowledge and Self-Assessment Program).

46 we highlight recent studies that advance the knowledge and understanding of the effects of various en

47 To evaluate patient motivations, knowledge, and decisions, as well as the impact of surge

48 rmined to date, discuss existing gaps in our knowledge, and make suggestions on necessary future stud

49 the tools we use to deliver information and knowledge are rapidly evolving, there is confidence in t

50 However, there is a lack of knowledge as to which drug pharmacokinetic (PK) characte

51 ation errors could reflect reliance on prior knowledge, as has been proposed for other systematic per

52 t Norovirus genogroups and expands a growing knowledge base on the interaction between positive-stran

53 present a new algorithm called PhenoCurve, a knowledge-based curve fitting algorithm, aiming to ident

54 and an electron donor has been exploited in knowledge-based drug design.

55 integrative energy function that combines a knowledge-based multibody potential and two atomic energ

56 zer mismanagement plus the implementation of knowledge-based N management practices.

57 e are many demonstrated successes from using knowledge-based potential energies, computing entropies

58 ences, environmental medicine, and molecular knowledge-based redox medicine.

59 We focus on new methods for physics-based, knowledge-based, and experimental data-directed modeling

60 the increasing amount of Semantic Web based knowledge bases in biology to use in machine learning an

61 truction of automatically annotated chemical knowledge bases that integrate chemical information and

62 ne interactions from biological pathways and knowledge bases, and analysis of the covariance of ovary

63 y pure morphological observation and, to our knowledge, brings a new perspective to molecular-scale u

64 Based on the same knowledge but thanks to new technologies, such hospitals

65 These novels are usually based on scientific knowledge, but they may arouse public concerns about tec

66 Here we address this gap in knowledge by using multiple sequencing approaches to gen

67 are mandated for those who act in a state of knowledge, compared with a state of recklessness.

68 There remain gaps in knowledge concerning how vascular morphology evolves dur

69 ainst morbilliviruses and provide additional knowledge concerning the mechanism of virus-mediated mem

70 The state of current knowledge concerning the microbiology, epidemiology, cli

71 This knowledge could be used to increase the efficacy of NAMP

72 ic class should be further explored, as this knowledge could inform paediatric treatment decisions.

73 d machine learning for the first time to our knowledge, could be a versatile tool for investigating t

74 ioinformatics toolkits that will lead to new knowledge discovery from their data.

75 eased scientific understanding, and top-down knowledge exchange patterns.

76 aphic, cultural, psychosocial, or transplant knowledge factors.

77 The prior knowledge fitting (ProFit) algorithm, with a new simulat

78 Preactivation of prior knowledge for faces showed as alpha-band-related and bet

79 Thus, our results reveal, to our knowledge for the first time, that IL-3 differentially r

80 This review will focus on the current knowledge for the main subclasses of flavonoids, includi

81 to visually represent integrated biocurated knowledge for use by both humans and computers.

82 There is now an opportunity to apply knowledge from NM toxicology and use it to better inform

83 hanges in c-di-GMP network proteins acquires knowledge from past experiences and enables bacteria to

84 Therefore, knowledge from the budding and fission yeast systems ill

85 l gene transfer processes, discusses the new knowledge gained from these approaches about both the ev

86 Knowledge gained from these studies could help in the de

87 ver more complex compounds by applying prior knowledge gained in new settings.

88 This work fills the knowledge gap by obtaining reliable values by quantum th

89 We addressed this knowledge gap by testing for multi-decade trends in spec

90 This knowledge gap hinders our ability to anticipate and miti

91 A key knowledge gap is how the capsid engages the NPC and what

92 One reason for such a knowledge gap is that typical models are complicated the

93 To begin to experimentally address this knowledge gap, we asked whether activation of PZ(Vgat) n

94 the present analysis sought to address this knowledge gap.

95 ellular homeostasis represents a significant knowledge gap.

96 his complex arrhythmia while unraveling more knowledge gaps and inadequacies of current therapeutic o

97 However, some knowledge gaps limit our ability to influence this compl

98 This study aimed at bridging knowledge gaps regarding the land-sea transport of per-

99 ussions focused on current understanding and knowledge gaps related to iron homeostasis, measurement

100 of small for gestational age (SGA), but some knowledge gaps remain, particularly regarding the role o

101 ement of ongoing transmission, and highlight knowledge gaps that must be addressed.

102 n ecosystem services in order to address key knowledge gaps, and present an overview of the options a

103 g the west Africa epidemic, identify ongoing knowledge gaps, and suggest priorities for future resear

104 As organizers explore new ways of sharing knowledge globally, it is crucial that the high quality

105 ssion, against Google's manually-constructed knowledge graph and against expert physician opinions.

106 embeddings to the prediction of edges in the knowledge graph representing problems of function predic

107 Our method can be applied to any biological knowledge graph, and will thereby open up the increasing

108 m the learned parameters and the constructed knowledge graphs were evaluated and validated, with perm

109 s that encode for related information within knowledge graphs.

110 Functional knowledge has been gained for its conserved methylated D

111 ic discovery that is agnostic to preexisting knowledge has uncovered dozens of loci that influence gl

112 y (the scientific study of traditional plant knowledge) has aided the discovery of important medicine

113 s approach remains underexplored and, to our knowledge, has not previously been applied in mycobacter

114 a-driven network model with prior biological knowledge (i.e., protein-protein interactions) for biolo

115 for studying language development and object knowledge in constrained laboratory settings, but also a

116 n winter, there is little hydro-climatologic knowledge in the cities impacted by snow.

117 he role of the medical congress in spreading knowledge in the face of this changing environment needs

118 Given the vast array of newly acquired knowledge in the field and technological advances, it is

119 nt injury after ischemic events, fundamental knowledge in these areas lag behind our current understa

120 notherapy, implementation of current and new knowledge in trial designs and interpretation of results

121 Here we present the first, to our knowledge, in vivo therapeutic micromotors application f

122 argue that visual attention and number word knowledge influence each other over development and cont

123 stand causal mechanisms and translating this knowledge into personalized prevention and management st

124 Implementation of new ECG knowledge is also important.

125 human cognition; and (2) intuitive physical knowledge is captured by qualitative representations, ra

126 tors are secreted during infection, yet such knowledge is essential to understand and combat crop dis

127 intuitive theories." We argue, instead, that knowledge is grounded in exemplar-based learning and gen

128 But human knowledge is too sparse and self-contradictory to be emb

129 and second-line NHT and, to the best of our knowledge, is the first to suggest that this assay be in

130 relate to executive functioning and semantic knowledge, leading to preserved cognitive performance in

131 s' knowledge remained greater than controls' knowledge (mean difference, 3.63; 95% CI, 2.49-4.78) (te

132 However, to the best of our knowledge murine models to study the biologic effects of

133 for neuromotor function, yet this was to our knowledge never done in neonatal lambs.

134 simulations are used to identify two, to our knowledge, new cholesterol-binding sites on the A2A aden

135 ntal observations, thereby providing, to our knowledge, new insight into how cell divisions influence

136 To our knowledge, no previous studies have evaluated the impact

137 To our knowledge, no study has investigated the association bet

138 We update the current knowledge of ARDS trends in incidence and mortality, ris

139 R = 6.2; 95% CI = 2.8-13.5; P < .001), prior knowledge of CD (aOR = 2.4; 95% CI = 1.0-5.8; P = .047),

140 tial of regulatory SNPs depend on inadequate knowledge of cell-specific DNA binding motifs.

141 clinical and biochemical information without knowledge of cMyC.

142 t of existing protein inhibitors rely on the knowledge of exactly how and how strongly a range of sma

143 ior flavivirus vaccine development programs, knowledge of flavivirus particle structure, definition o

144 Here, I summarize key features of current knowledge of genomic editing by CRISPR/Cas9 technology a

145 s have involved the primary auditory cortex; knowledge of higher-order areas is limited to effects of

146 tudy was the need for assumptions concerning knowledge of HIV status and ART coverage among adults no

147 rocesses on interdependent spatial networks, knowledge of how interdependent spatial networks influen

148 However, mechanistic knowledge of how it functions and its interactions with

149 ance of the host microbiome and accumulating knowledge of how it regulates and maintains a healthy hu

150 hms are highly detrimental to health, deeper knowledge of how our biological clocks change with age m

151 ted and maintained in tissue sites; however, knowledge of human antiviral T cells is largely derived

152 of methylome data that contain comprehensive knowledge of human diseases.

153 As knowledge of immune function and appreciation of immunod

154 spin resonance (ESR) measurements and recent knowledge of lifetime excited states in MIL-125-type of

155 ding site in GPR39 for synthetic ligands and knowledge of ligand binding to other receptors with simi

156 Communicating the current knowledge of medical outcomes after live kidney donation

157 mechanism adds significant insight into our knowledge of mRNA-specific translational activation and

158 Sound knowledge of neoplasms affecting the sternum and their i

159 n, the past 5 years has seen an expansion in knowledge of new cellular regulators and roles of CRTCs

160 of human activities on TOC changes requires knowledge of past concentrations; however, water-monitor

161 During the past decade, knowledge of pathogen life history has greatly benefited

162 Incorporating knowledge of polymorphisms that occur before the emergen

163 pest management (IPM) makes decisions using knowledge of population dynamics and threshold insect de

164 Knowledge of RNA three-dimensional topological structure

165 Scales that served as covariables were Knowledge of Survivorship Issues, Perceived Efficacy in

166 The knowledge of the affected sequences provides novel infor

167 Knowledge of the atomic details of these structures help

168 To the best knowledge of the authors, this study offers the first hi

169 ead "net" for cancer cells, without a priori knowledge of the cancer type.

170 ng probabilities, used in concert with prior knowledge of the canonical secondary structure, allow ac

171 e total possible reactions without any prior knowledge of the chemistry.

172 e cell lysates can be obtained without prior knowledge of the concentration of the expressed protein,

173 Knowledge of the context that determines the nature and

174 Despite greatly improved knowledge of the disease, therapeutic choices are insuff

175 ve strategies have been prevented by gaps in knowledge of the epidemiology of congenital cytomegalovi

176 This review describes the current knowledge of the epidemiology, clinical presentation, tr

177 port that healthcare providers have adequate knowledge of the etiology of diarrhea and the severe sig

178 new therapies are still limited by a lack of knowledge of the functions and pathobiological mechanism

179 Our knowledge of the fungal microbiome (mycobiome) is limite

180 been designed without a strong foundational knowledge of the immune landscape present in NSCLC.

181 Thus, knowledge of the impact of management practices and dist

182 Knowledge of the mechanism of formation, levels and toxi

183 Despite the knowledge of the mechanisms underlying neural and mechan

184 Given our increasing knowledge of the molecular pathogenesis of S. aureus dis

185 Here the current state of knowledge of the NVU will be assessed, focusing on one o

186 , and the analysis outcome relies on precise knowledge of the probe and analyte concentrations.

187 It also increases our knowledge of the role branched-chain amino acid cataboli

188 More research is needed to inform our knowledge of the role of insurance and health-care deliv

189 digrade desiccation tolerance, expanding our knowledge of the roles and diversity of disordered prote

190 A proper knowledge of the sources of (236)U is an essential prere

191 However, knowledge of the structure of these regeneration tracks

192 e derived from the physical nature and prior knowledge of the system under study.

193 Detailed knowledge of the T cell response may further contribute

194 e of such kinetic processes without detailed knowledge of the underlying biochemical reactions.

195 by neurons within the visual system, current knowledge of their causal basis, and methods for assessi

196 apply these materials in deformable devices, knowledge of their mechanical response to dynamic strain

197 as design has been limited by the incomplete knowledge of their mechanism.

198 Knowledge of their single-crystal X-ray structures has b

199 ng to support their intracellular cycle, but knowledge of these pathogenic processes is limited.

200 A fundamental knowledge of these photophysical processes is crucial fo

201 As our detailed knowledge of these viral proteins improves, we will undo

202 s a significant step forward in the chemical knowledge of this material.

203 of erythropoiesis and identifies gaps in our knowledge of what molecular damage may be incurred by ox

204 Greater knowledge of why CMV infection usually fails may provide

205 Leveraging the extensive knowledge of yeast transcriptional regulation, we uncove

206 sident airway cells is critical to advancing knowledge on asthma pathogenesis and the development of

207 Here, I review the current state of knowledge on CMG mutations in FL, discuss their potentia

208 sion data that makes use of prior biological knowledge on gene-regulatory interactions in order to in

209 resents a fundamental resource to deepen our knowledge on long noncoding RNAs in C3 cereals, allowing

210 e and sepsis is steadily increasing, but the knowledge on long-term survival in this group is scarce.

211 This study not only expanded our knowledge on novel sRNAs but would also give us new insi

212 drug discovery approaches, but also to gain knowledge on TEAD regulation.

213 o provide a critical overview of the current knowledge on the effectiveness of AIT and its potential

214 These results provide new knowledge on the genetic basis of milk synthesis and wil

215 iset et al. provide new data that extend our knowledge on the mechanisms whereby Streptococcus pneumo

216 In this review, I summarize the current knowledge on the mode of activation and processing that

217 Despite the considerable existing knowledge on the molecular control of cell movements, it

218 is consensus document summarizes the current knowledge on the potential for precision medicine in foo

219 gosaccharides is often hindered by a lack of knowledge on the reactivity and selectivity of their con

220 The results advance our knowledge on the role of sensory input in the generation

221 organismal effects without prior mechanistic knowledge or complex exposure data.

222 o integrate them with existing structures of knowledge or schemas.

223 Likewise, animals benefit from knowledge parsing their environment into larger spatial

224 Here we show, to our knowledge, previously unreported temporal dynamics of th

225 These data reveal a new and, to our knowledge, previously unsuspected role for postsynaptic

226 This study, to our knowledge, provides our first detailed glimpse into the

227 change practice can lead to improved nurses' knowledge, quality of care, and patient outcomes.

228 thogens in Pinus species, increasing current knowledge regarding induced systemic resistance (ISR) to

229 al models of FSHD are hindered by incomplete knowledge regarding the conservation of the DUX4 transcr

230 In this minireview, we integrate current knowledge regarding the natural origin and occurrence of

231 elated to racial/ethnic identity and advance knowledge related to the pathogenesis of triple-negative

232 After 1 week, intervention participants' knowledge remained greater than controls' knowledge (mea

233 hod combines symbolic methods, in particular knowledge representation using symbolic logic and automa

234 t this research is vital in underpinning the knowledge required to realize the full potential of plas

235 role nor specialty was associated with total knowledge score in multivariate analysis (P = 0.13 and 0

236 ns without feature engineering or the use of knowledge sources.

237 This gap in knowledge stems from a lack of understanding of the phys

238 We reconstruct a map-like knowledge structure directly from a hippocampal-entorhin

239 projection and incorporate prior biological knowledge (such as pathway information) to learn more me

240 d is more consistent with current biological knowledge than the SPACE method.

241 d very important outcome of this work is the knowledge that now we have demonstrated that these devic

242 ociated with self-reported gains in parental knowledge that were retained for 7 months.

243 We also show for the first time, to our knowledge, that lipin-1 knockdown significantly inhibits

244 dings demonstrate for the first time, to our knowledge, that T cell-derived CD70 plays a novel immune

245 lectivity of 11 at 100 K, to the best of our knowledge the largest value known to date.

246 of organic contaminants, and to the authors' knowledge the material has not been investigated previou

247 go pygmaeus), and for the first time, to our knowledge, the external application of an anti-inflammat

248 xed-effects meta-analysis, including, to our knowledge, the first analysis of the X chromosome.

249 Together, these data provide what is, to our knowledge, the first conclusive evidence that ARPKD is n

250 Our study provides, to our knowledge, the first estimates of the fitness cost and b

251 Our study provides, to our knowledge, the first in vivo microrheological measuremen

252 he plastid genome of Polytoma uvella: to our knowledge, the first report of ptDNA from a nonphotosynt

253 ent quenchable amorphous diamond has, to our knowledge, the highest density among amorphous carbon ma

254 INTERPRETATION: This study, which is to our knowledge, the largest trial of CIDP to date and the fir

255 Furthermore, to our knowledge, the optimal management of eyes with endophtha

256 To our knowledge, the results of this study are the first sugge

257 tudy, we explored for the first time, to our knowledge, the role of PIKfyve in human and mouse neutro

258 study investigates-for the first time to our knowledge-the existence and mechanisms of functional int

259 To our knowledge, there are no published recommendations on the

260 To our knowledge, these are the first spontaneously formed Panc

261 of neutrophil plasticity is new and, to our knowledge, these data are the first evidence that neutro

262 To our knowledge, these data show for the first time that the m

263 To our knowledge this work represents the most comprehensive te

264 To the best of our knowledge, this efficiency is among the highest values f

265 To the best of our knowledge, this is a threefold higher power output than

266 INTERPRETATION: To our knowledge, this is the first detailed case report sugges

267 To our knowledge, this is the first evidence that some mammals

268 To the best of our knowledge, this is the first functional characterization

269 To our knowledge, this is the first propensity score-matched an

270 To our knowledge, this is the first protocol that provides a co

271 INTERPRETATION: To our knowledge, this is the first randomised controlled trial

272 To our knowledge, this is the first report evaluating (89)Zr-tr

273 To our knowledge, this is the first report of nucleolar functio

274 To our knowledge, this is the first report showing endogenous m

275 To our knowledge, this is the first report showing that orally

276 Conclusion To our knowledge, this is the first reported anti-PD-L1 plus ol

277 To our knowledge, this is the first study demonstrating inflamm

278 To the best of our knowledge, this is the first study demonstrating Se tran

279 To the best of our knowledge, this is the first study that describes the us

280 To our knowledge, this is the first study to investigate the lo

281 To the best of our knowledge, this is the first time that identification an

282 INTERPRETATION: To our knowledge, this is the largest randomised controlled tri

283 To our knowledge, this is the most extensive analysis of primar

284 To our knowledge, this represents the first example of a MOF ca

285 To our knowledge, this significant improvement results in the l

286 To our knowledge, this study is among the few large, population

287 To our knowledge, this study is the first demonstration of an i

288 To our knowledge, this study shows for the first time that PRIT

289 Thus, to the best of our knowledge, this transformation represents the first exam

290 To our knowledge, this vascular plasticity is unique among mamm

291 To our knowledge, this was the first randomized trial to evalua

292 To our knowledge, this was the first specific quantification of

293 To the best of our knowledge, through combination of solid-state metathesis

294 This is the first study to our knowledge to calibrate a model of ART impact to populati

295 ence position 69 (Eos notation) and use this knowledge to create "pr"- (for primed convertible) varia

296 efforts should focus on how to exploit this knowledge to effectively control infections caused by C.

297 llection, monitoring, analysis, integration, knowledge-translation, and data archiving phases of CAN-

298 With this knowledge, we are poised to design the next generation o

299 Parental behavior and knowledge were assessed through immediate (n = 16111) an

300 for the inclusion of missing data and prior knowledge, while investigating associations in the data.