ライフサイエンスコーパス: known

1 the mammalian intestinal epithelium were not known.

2 the genome is organized and delivered is not known.

3 elated donor (URD), and methotrexate are not known.

4 ying mechanisms and functional roles are not known.

5 egative (HIV-) brain-dead donor (BDD) is not known.

6 nisms underlying this increased risk are not known.

7 CF, and TERRA in telomere replication is not known.

8 tomography criteria have mild disease is not known.

9 nts may influence one another is only partly known.

10 duce a panoply of antimicrobial peptides now known.

11 coordinated through a single receptor is not known.

12 ese different activities are mediated is not known.

13 ruitment and effector differentiation is not known.

14 ng simulated data when the ground truths are known.

15 emia, is one of the most infectious bacteria known.

16 molecular pathomechanisms are not precisely known.

17 ver, the mechanistic role of EEA1 is not yet known.

18 Relatively little is known about changes in bee community composition in the

19 opsis (Arabidopsis thaliana), very little is known about floral induction in tulip.

20 Very little is known about how archaeal cells orchestrate transcription

21 causes beta-cell dysfunction, but little is known about how cells handle excess fuels to avoid toxic

22 However, little is known about how cells sense and respond to mechanical co

23 Little is known about how donor factors, timing of procurement, an

24 However, little is known about how genes are specifically affected by early

25 Little is known about how genetic variation and epigenetic marks i

26 However, surprisingly little is known about how LMP1 expression is regulated in epitheli

27 y of protein-encoding transcripts, little is known about how miRNAs themselves are degraded.

28 However, little is known about how the activity of these proteins is regula

29 neurotransmitters, but relatively little is known about how they are formed.

30 fferent fatty acids; however, very little is known about how zDHHC enzymes contribute to acyl chain h

31 educe mortality or hospitalizations, less is known about its effect on health status.

32 ery is conserved between kingdoms, little is known about its evolution.

33 demonstrated its high prevalence, little is known about its potential consequences on visual functio

34 lling of target cells; however, much less is known about its role in NK cells.

35 y of anion channels in plants, but little is known about most of its members.

36 Little is known about placental vitamin D metabolism and its impac

37 gulating harmful algal blooms, but little is known about the biochemical and physiological changes as

38 been characterized biochemically, little is known about the biology of amyloidogenic plasma cells (P

39 l on the timescale of seconds, and little is known about the downstream effects from this modulation.

40 lyst activity and selectivity, yet little is known about the dynamic compositional and structural cha

41 Little is known about the function of the cholinergic efferents in

42 Little is known about the functional development of individual neu

43 Although much is known about the hydraulics of xylem, the hydraulic inter

44 Little is known about the impact of another testing strategy, rout

45 biology to computer science, still little is known about the impact of environmental changes on an ar

46 Relatively little is known about the in vivo functions of newly emerging gene

47 y a role in viral persistence, but little is known about the kinetics of the generation, the tissue d

48 However, little is known about the mechanism(s) by which this feedback occu

49 e under conditions of hypoxia, but little is known about the mediators of this effect.

50 associated with preterm birth, but little is known about the microglial response in preterm infants.

51 However, little is known about the molecular and cellular determinants in m

52 Little is known about the molecular mechanisms driving vaccine imm

53 nitiators of immune responses, but little is known about the molecular pathways used by DCs to sense

54 rast to a wealth of human studies, little is known about the ontogeny and consistency of empathy-rela

55 r clean energy via hydropower, but little is known about the potential impact of dam-building on the

56 Virtually nothing is known about the relevance of glycolysis in patients with

57 essential for normal development, little is known about the specific functions of the different MLL

58 However, little is known about the specific relationship between asthma and

59 nately of the protein Ribeye, very little is known about the structural dynamics of ribbons.

60 lity in HFpEF is sudden death, but little is known about the underlying mechanisms.

61 Although much is known about the underlying signaling pathways, it remain

62 tumor antigen-specific T cells, but less is known about their effects on natural killer (NK) cells,

63 haracterized in model organisms, but less is known about these basic aspects of cell biology in early

64 any learning and memory processes, little is known about these properties specifically on cue-activat

65 Little is known about these small RNAs in litchi (Litchi chinensis

66 equilibrium is well understood, much less is known about tipping of oscillations (limit cycles) thoug

67 However, little is known about whether and how long-range cross-frequency c

68 repair and healing after ischemia, little is known about whether T cells directly impact cardiac fibr

69 peptides with DPP-IV inhibitory features or known activity were identified by liquid chromatography-

70 ude amyloidogenic peptides, such as the well-known amyloid-beta peptide involved in Alzheimer's disea

71 oduced several simple models inspired by the known anatomical structures and neuronal responses withi

72 In summary, we validated known and identified additional determinants for wrinkli

73 equences promises unbiased identification of known and novel microbes.

74 The expression patterns of known and putative SSP genes based on 144 RNA sequencing

75 Lutein is a carotenoid presenting known anti-inflammatory and antioxidant properties.

76 We identified Flunarizine - a well-known anti-migraine calcium channel (CC) blocker - being

77 D is an environmental and dietary agent with known anticarcinogenic effects, but protection against b

78 aco, one of the sources of the ancient resin known as "dragon's blood".

79 The glomerular filtration barrier is known as a 'size cutoff' slit, which retains nanoparticl

80 ly visual cortex results in a visual percept known as a phosphene.

81 alues for a family of 16 literature ligands, known as bpp(X,Y) [X,Y-substituted 2,6-(pyrazol-1-yl)pyr

82 IP2 (TRAF3 Interacting Protein 2; previously known as CIKS or Act1) is an oxidative stress-responsive

83 thetic-biology approach based on a technique known as codon shuffling.

84 hey possess shorter superposition lifetimes, known as coherence times or T2, due to interactions with

85 requently experience clinical deterioration, known as cryptococcosis-associated immune reconstitution

86 d proteins, binds specifically to GODZ (also known as DHHC3), a cellular Golgi apparatus-specific Asp

87 a), but can develop uncontrollable movements known as dyskinesia upon treatment with L-DOPA.

88 The alpha-helical region of separase (also known as Esp1) contains four domains (I-IV), and a subst

89 knockdown of folate receptor 1 (Folr1; also known as FRalpha) impairs neural tube formation and lead

90 s can be beneficial for health and survival, known as hormesis.

91 Freeze casting, also known as ice-templating, is a technique that has receive

92 The leukocyte integrin Mac-1 (also known as integrin alphaMbeta2, or CD11b/CD18) is crucial

93 IRAK-M, also known as IRAK-3, is an inhibitor of proinflammatory cyto

94 ly up-regulated mammalian lncRNA, FOXD3-AS1, known as linc1623 in mice, in the setting of hyperoxia/r

95 oles for bacterially derived vitamin K forms known as menaquinones in health and disease, which may b

96 K(lysine) acetyltransferase 8 (KAT8, also known as MOF) mediates the acetylation of histone H4 at

97 sor factor RE1-silencing transcription (also known as neuron-restrictive silencer factor) to position

98 lves a multivariate resolution curve fitting known as non-negative matrix factorization with alternat

99 ng strand is replicated in discrete segments known as Okazaki fragments.

100 n added by ADP-ribosyltransferases, commonly known as PARPs, but it can also be added by other enzyme

101 he major surface antigen of the blood stages known as Pf EMP1 encoded by up to 60 var genes per genom

102 c amino acid phenylalanine (Phe) in animals, known as phenylketonuria, are mitigated by excretion of

103 protein tyrosine phosphatase (TC-PTP), also known as PTPN2, as a negative regulator of IL-7R-STAT si

104 tion of the organic-rich (sapropel) interval known as S5.

105 e black hole at the center of the Milky Way, known as Sagittarius A* (Sgr A*), may have affected the

106 t 50 years one such lineage of meningococci, known as serogroup A, clonal complex 5 (A:cc5), has caus

107 n in the scavenger receptor B1 (SCARB1; also known as SR-B1) gene.

108 This phenotype, known as T cell exhaustion, occurs during chronic infect

109 ing neurodegenerative disorders collectively known as tauopathies.

110 festation by Myzus persicae Sulzer, commonly known as the green peach aphid (GPA), which is an import

111 can permeabilize tissue through a phenomenon known as transient cavitation, can be used to deliver RN

112 e HSV-1 virion protein 13/14 (VP13/14), also known as UL47, is a tegument antigen targeted by CD8(+)

113 uman cytomegalovirus signal-anchored protein known as viral mitochondria-localized inhibitor of apopt

114 One of the Yops, YopO (also known as YpkA) obstructs phagocytosis through disrupting

115 ns of the recombination regulator Cst9 (also known as Zip3).

116 0A9 (solute carrier family 30 member 9; also known as ZnT-9) is ubiquitously expressed with high leve

117 We also identified several CNVs that include known ASD genes (SHANK3, CDH10, CSMD1) or genes involved

118 re transmitted via insect vectors, little is known at the molecular level as to how the viruses are r

119 lls with a natural disaccharide trehalose, a known autophagy enhancer, delays SG assembly and facilit

120 of states, clearly distinct from the widely known, bulk-like sigma- and pi-gaps.

121 at the use of two standards of CO2 in air of known but differing delta(13)C and delta(18)O isotopic c

122 reover, in contrast to their action on other known carbohydrates, both KCl and NaCl act as salting-ou

123 r, ubiquitin (Ub), regulates virtually every known cellular process in eukaryotes.

124 y smoking phenotype, we reconfirmed the well-known CHRNA5-CHRNA3-CHRNB4 genes and further yielded a n

125 ese CDMS measurements by using proteins with known collisional cross-sections for calibration.

126 erences in body composition in early life, a known contributor to obesity risk.

127 get identification and contact selection are known contributors to variability in efficacy across dif

128 uated DENV isolates.IMPORTANCE The lack of a known correlate of protection and the failure of a neutr

129 Human MSN modules recapitulate known cortical cytoarchitectonic divisions, and greater

130 Despite its known detrimental effects, iron deficiency remains the m

131 (FFPE) tissues and sterile body fluids with known diagnosis of IFD based on reference method results

132 Surprisingly, despite known differences in the number of secretory cells in ge

133 o or stronger than the effects of other well-known drivers of productivity, including climate and nut

134 These well-known drug reservoirs can be used as smart carriers for

135 Here we review the known ecological and evolutionary implications of symbio

136 imed replication origins connecting the long-known effect of genomic context on replication timing to

137 tes of phosphene perception closely resemble known electrophysiological correlates of conscious perce

138 hares some similarities to responses to well-known elicitors such as chitooligomers and OGs.

139 kella multacida (PhyAmm) in complex with the known eukaryotic second messengers Ins(1,3,4,5)P4 and In

140 It is not known exactly where amyloid-beta (Abeta) fibrils begin t

141 Understanding the relationship between known factors and spending increases over time could inf

142 Such a pressure induced transition is known for covalent liquids, but has not been observed fo

143 e existence of catalytic antibodies has been known for decades.

144 The causative genes are known for fewer than 40% of PCLD index cases.

145 RNA interference (RNAi) is known for its high catalytic activity and target selecti

146 sity of water with applied pressure has been known for over a century.

147 bolites produced by brown seaweed, which are known for their nutraceutical and pharmacological proper

148 vocal detection of multiple chemical markers known for their use in the adulteration and counterfeiti

149 on shows similarities to the Birch reduction known from organic chemistry.

150 ir finite size, show features of criticality known from phase transitions in physical systems.

151 is confined to the nucleus, consistent with known functions of each of these two proteins.

152 Unlike the other 14 known galectins in mammalian cells, which have dimeric o

153 ogenic variant p.Ala13Thr variant in MYL2, a known gene for HCM.

154 Mutations in LRRK2 represent the most common known genetic cause of PD.

155 , thus enabling the functional validation of known genetic risk factors and potentially pathogenic al

156 ed variants represent a tiny minority of all known genetic variation, and therefore there is necessar

157 he reactive intermediates are converted to a known genotoxic scaffold, providing metabolic support of

158 "- (for primed convertible) variants of most known green-to-red pcFPs.

159 Herbaspirillum rubrisubalbicans is a well-known growth-promoting rhizobacteria that can also act a

160 Participants with known hypertension in communities that had all four drug

161 It is not known if the other major types of pyramidal neurons in t

162 allergic contact dermatitis (ACD), it is not known if they are mediated by shared or distinct signali

163 ational age <32 weeks, birth weight <1000 g, known immunodeficiency or no Danish-speaking parent.

164 To compare the effects of both variants with known inactive GDP- and active GTP-bound RAB11B mutants,

165 st five years of life, often after the first known ingestion with typical rapid onset IgE-mediated sy

166 rface electrostatics with few, hitherto best known inhibitors of SOCE.

167 This method takes advantage of known interactions extracted from multiple sources such

168 No known iron complexes are considered photoluminescent at

169 We demonstrate JH receptor expression in known JH target tissues, in which temporal expression co

170 e details about the distribution of the well-known Lewis pairs, such as how they are distributed in s

171 cancer cells is questionable, given the well-known limitations of tumor-associated macrophages (TAMs)

172 stump carcinoma is an exceptional and poorly known long-term complication after pancreaticoduodenecto

173 monoclonal antibodies (MAbs) that recognize known major antigenic sites in MeV-H, we identified a D4

174 The currently known mechanisms for active forgetting include neurogene

175 Here we found that known membrane insertion pathways fail to effectively en

176 r features (positive ion mode), including 70 known metabolites, in single dorsal and ventral cells in

177 mokers in two Swedish cohorts, differing for known MS risk factors.

178 e NRP1 cytoplasmic domain (NCD), but not the known NCD interactor GIPC1.

179 ctrolyte is demonstrated by modifying a well-known negative photoresist, SU-8, with LiClO4 .

180 otonin (5-hydroxytryptamine, 5-HT) is a well-known neurotransmitter that is involved in a growing num

181 Any patient with no known ocular disease who desires a routine eye screening

182 eption of one inconclusive study, nothing is known of the genetic basis of this phenomenon.

183 saurus, Moabosaurus and Zby), was previously known only from the Jurassic of Europe.

184 Of the thousands of extrasolar planets now known, only six have been found that transit hot, A-type

185 photoconversion dynamics of Dendra2, a well-known PAFP used in localization microscopy.

186 y represents an estimated 20% of the world's known patients with Progeria.

187 one specimens from 20 exhumed individuals of known period of burial and age at death is described.

188 ppearance of neural maps, which we link to a known phase transition in an Ising-like model from stati

189 he receptor, which are indicated by its only known physiological ligand, podoplanin, being an integra

190 t skin pigmentation is highly heritable, but known pigmentation loci explain only a small fraction of

191 Nor is it known precisely how villus cell migration is affected wh

192 None are known previously for fossil odonatans.

193 6%) were in non-anticoagulated patients with known prior AF.

194 he abnormal aggregation of a small number of known proteins underlies the most common human neurodege

195 Components of e-cigarette aerosol have known pulmonary toxicity.

196 ing have been extensively studied, little is known regarding how tumor cell rolling on selectins faci

197 a published flea genome sequence, little is known regarding R. typhi biology in flea vectors that, i

198 older individuals, very little is currently known regarding regional changes in spontaneous BOLD sig

199 Yet little is known regarding the direct effects of IL-4 on keratinocy

200 Wnts are known regulators of synapse formation, and our data reve

201 These findings, along with the well-known regulatory roles that SIRT1 plays in modulating bo

202 he most memory-efficient classical algorithm known requires infinite memory, while a quantum simulato

203 = 1) or ciprofloxacin (n = 1) in addition to known resistance determinants, collectively termed the "

204 Among patients without known risk factors for iron deficiency, gastric acid inh

205 For each helminthiasis, known risk factors, symptoms, and suggested options for

206 o highly conserved loop regions of uS12 with known roles in maintaining the accuracy of mRNA codon tr

207 proteome library from DIA data and to query known sequence variants.

208 Using a known series of triphenylamine-based dyes bearing haloge

209 al of A. baumannii in NHS, including already known serum resistance factors, and many novel genes not

210 autophosphorylated protein, we expand on the known set of CPK28 autophosphorylation sites, and we dem

211 d method to compare allele read fractions at known single-nucleotide polymorphisms, considering depth

212 The most widely known solar geoengineering proposal is stratospheric aer

213 ion sites to protein-protein interactions of known structure and analysing the properties of the prot

214 the impact of AbetaOs in astrocytes, a less known subject.

215 atients with history of ASA sensitivity with known/suspected stable coronary artery disease or presen

216 The second domain has a known SWIB/MDM2 fold, which was not observed before in o

217 erentiation of progenitors transduced with a known Tcra gene in the presence of antigen drives differ

218 We identify clusters corresponding to known tetraloop folds such as GGUG, RNYA, AGNN, and CUUG

219 Physiologists have long known that CO2 directly affects acid-base and ion regula

220 While it is known that ghrelin inhibits glucose-stimulated insulin s

221 Although it is known that gross chromosomal abnormalities are remarkabl

222 Although it is known that METH dysregulates both dopamine transmission

223 As a countermeasure, numerous phages are known that produce proteins to block the function of cla

224 though the atomic structure of T4 is largely known, the dynamics of its fascinating injection machine

225 on uses the most structurally complex glycan known: the plant pectic polysaccharide rhamnogalacturona

226 on and gold nanoparticles (Au-NPs) to induce known thermal decomposition reactions that cleave peptid

227 and well documented cases of island dwarfing known thus far took place over thousands of years.

228 ion and propensity score matching of factors known to affect recurrence to assess independent effects

229 Many ions are known to affect the activity, stability, and structural

230 MicroRNAs (miRNAs) have been known to affect various biological processes by repressi

231 the aggregation end products of fibrils are known to arise due to microstructural differences among

232 altered bodily sensations-both of which are known to be associated with insular functioning.

233 Traffic-related air pollution is known to be associated with skin aging manifestations.

234 le, expanding the arsenal of defence systems known to be at the disposal of prokaryotes against their

235 2A/B proteins form a coiled-coil interaction known to be critical for the formation of NuRD.

236 sphatidylcholine biosynthesis, that were not known to be essential for phototrophic growth.

237 TFIIH, whose recruitment to the PIC is known to be facilitated by the Mediator, then acts to re

238 eoperative temporal lobe white matter tracts known to be important in the generation and propagation

239 contains a hydrophobic triad W1L4L8 that is known to be important in the interaction with centrin.

240 tressor.Animals' response to acute stress is known to be influenced by sex and genetics.

241 (2) Single nucleotide polymorphisms (SNPs) known to be involved in human eye colour variation showe

242 gand stromal cell-derived factor (SDF)-1 are known to be involved in inflammation.

243 not induced, including at enhancers that are known to be repressed by a transcriptional repressor.

244 increases enzymatic activity of two key MMPs known to be secreted and activated in neuroinflammation,

245 tif, mutating it to CX4C ((182)CWAIAC(187)), known to block binding to CX3CR1, might decrease disease

246 Optimizing a compound known to block the H3K27me3 site in EED discovered by in

247 ver that NAD(P)H oxidase 4 (NOX4), an enzyme known to catalyse the oxidation of NAD(P)H, is upregulat

248 Spinach is known to contain significant amounts of oxalates, which

249 s and consists of the most polymorphic genes known to date.

250 lucocorticoid steroids, like prednisone, are known to delay loss of ambulation in patients with Duche

251 ed junctions of orthopaedic hip implants are known to differ and the debris generated varies in size,

252 tem, we first tested thiram, a DTC pesticide known to display neurotoxic effects, observing that it c

253 Mutants of the fusome, an organelle that is known to facilitate intracyst communication, compromise

254 Circularly polarized photons are known to generate a directional helicity-dependent photo

255 ns in the PBX homeobox 1 gene (PBX1), a gene known to have a crucial role in kidney development.

256 doping.Two-dimensional Dirac semimetals are known to host fermionic excitations which can mimic phys

257 tion (MIA) via infection during pregnancy is known to increase risk for autism spectrum disorder (ASD

258 temporal proximity to environmental impacts known to induce oxidative stress.

259 thene (TCE) by in situ minerals, and C2H2 is known to inhibit bacterial dechlorination.

260 id activation of cannabinoid (CB1) receptors known to inhibit presynaptic GABA release was significan

261 's sarcoma-associated herpesvirus (KSHV) are known to interact extensively with the DDR during the co

262 These regions contained genes known to interact with estradiol metabolism and cancer.

263 R-loops are known to interfere with replication forks, and sensitivi

264 et C-type lectin-like receptor 2 (CLEC-2) is known to maintain the physiological state of blood vascu

265 Tumor necrosis factor receptor 2 (TNFR2) is known to mediate immune suppression and tissue regenerat

266 ar to act in any of the three major pathways known to mend DNA DSBs, namely homologous recombination

267 Lightning strikes are known to morphologically alter and chemically reduce geo

268 ent het-siRNAs also requires several factors known to participate in the effector portion of the RdDM

269 iotic usage toward antibiotics traditionally known to place patients at greater risk for CDI experien

270 -described activity-dependent mechanisms are known to play a key role in learning and memory.

271 e peptides isolated from natural sources are known to play important physiological roles in the human

272 m 2 is conserved between mouse and human and known to play key roles in neuronal function.

273 In general, clinicopathological factors known to predict and drive allograft fibrosis include gr

274 pression.SIGNIFICANCE STATEMENT Saccades are known to produce a suppression of contrast sensitivity a

275 Although proteasome-mediated proteolysis is known to produce antigenic peptides in adaptive immunity

276 ANG), a secreted vertebrate ribonuclease, is known to promote cell proliferation, leading to neovascu

277 BABY BOOM (BBM) genes in angiosperms are known to promote somatic embryogenesis, which like apoga

278 The pupil is known to reflect a range of psychological and physiologi

279 NCA following treatment with different drugs known to regulate alpha-SYN expression; while exogenous

280 rotein HYLS-1 is the only centriolar protein known to remain at the base of mature cilia and is requi

281 It is known to sense several stimuli that are potentially asso

282 tinct subtypes of inhibitory interneuron are known to shape diverse rhythmic activities in the cortex

283 ein, represents the first documented protein known to stimulate transforming growth factor (TGF)-beta

284 Some microRNAs (miRNAs) are known to suppress breast cancer.

285 of 7,300-10,000 kelvin), and no planets are known to transit the even hotter B-type stars.

286 paradoxical because these steroids are also known to trigger muscle atrophy.

287 o-terminal domain with a fold distinct among known TRP structures, together with the carboxyl-termina

288 es that encode 80 genes, including novel and known virulence factors associated with adherence and au

289 ysis and genomic comparisons with previously known viruses.

290 a missing date of birth, diagnosis, or last known vital status.

291 transmitter for this biofilm response is not known, we find that addition of hydrogen sulfide gas to

292 he metabolic etiology of her lens changes is known, whereas the pathogenesis of ONHD is not clear.

293 00 acetyltransferase activity, but it is not known whether CBP activity is controlled similarly.

294 crucibles for rapid evolution, but it is not known whether evolutionary changes arise mainly after su

295 However, it is not known whether intravenous thrombolysis (IVT) is of added

296 However, it is not yet known whether or how sensory stimulation might trigger a

297 se-associated factor 1 (Paf1), but it is not known whether TEFs have gene-specific functions.

298 and while it is highly conserved, it is not known whether the functional role of this splicing is al

299 icy preferences are private information, not known with certainty by the other politicians with whom

300 rprinting and linear combination analysis of known XANES reference compounds.