ライフサイエンスコーパス: labeled at

1 administered daily in controlled oral doses labeled at 0, 25, 125, and 250 micro g cholecalciferol f

2 Intrinsic KIEs from MTAs labeled at 1'-(3)H, 1'-(14)C, 2'-(3)H, 4'-(3)H, 5'-(3)H,

3 In this work, FRP was labeled at 1:1 molar ratio with the fluorophore eosin.

4 tryptic bovine serum albumin (BSA) peptides labeled at 1:1:1, 10:5:1, and 1:5:10 ratios, achieving m

5 The protein was labeled at 11 water-exposed and lipid-covered sites, and

6 ing activity was enriched in organelles that labeled at 15 degrees C, but not at 4 degrees C, that ex

7 t only 13% of the lens epithelial cells were labeled at 18.5 weeks.

8 of the peptic fragments derived from alphaTS labeled at 3 M urea indicates that most of the region be

9 Only RPE65 is labeled at 5 microM 1 at 4 degrees C.

10 capture probe (CP) with methylene blue (MB) labeled at 5' end is modified on the pretreated electrod

11 DNA labeled at 5'end using 6-mercapto-1-hexhane (HS-ssDNA) i

12 Adenines labeled at [6-13C], [6-15N], [6-13C, 6-15N], and [1-15N]

13 illin headpiece subdomain protein (HP36) was labeled at a "single" site corresponding to any one of t

14 The 35-kDa band was half-maximally labeled at a [(3)H]6-AziP concentration of 1.9 microM, w

15 Children were labeled at a median (IQR) age of 1.3 (0.9-2.3) years.

16 ion was found to be much longer lived, being labeled at a rate of only 0.2% per day (corresponding to

17 Chloroplast ATPase F1 was labeled at a single cysteine residue by OPBM and trypsin

18 ioinspired peptide phenylalanine (Phe) (19)F-labeled at a single site, altering its liquid-liquid pha

19 The annexin V-128 protein, labeled at a single specific site at the N terminus, sho

20 g technique, in which one type of subunit is labeled at a time, to carbonmonoxy-hemoglobin A (HbCO A)

21 Second, we have used S4 labeled at a unique cysteine with either of two fluoroph

22 tested using a set of HFPs that were (13)CO-labeled at Ala-14 and (15)N-labeled at either Val-2, Gly

23 On the (+)-side, alpha1M3 was labeled at Ala-291 and Tyr-294 and gamma2M3 at Ser-301,

24 CB(1)(T377-E416) specifically (2)H- or (15)N-labeled at Ala380 and reconstituted in membrane-mimetic

25 and a proof of mechanism for (68)Ga-FAPI-74 labeled at ambient temperature.

26 pffs in neurons, we developed a pff species labeled at amino acid residue 114 with the environmental

27 occur upon binding of a T4L variant, bimane-labeled at an alternative solvent-exposed site, establis

28 CNV complexes are labeled at an earlier stage and more reproducibly than w

29 oving limitations on the quantity of protein labeled at any one time significantly decreases the cost

30 andard assay, one end of the dsDNA helix was labeled at apposing 5' and 3' ends with hexachlorofluore

31 in a series of Sup35NM fibril samples, (13)C-labeled at backbone carbonyl sites of Tyr, Leu, or Phe r

32 kinetics of DNA bending by M.EcoRI using DNA labeled at both 5'-ends and observed changes in fluoresc

33 escent double-stranded DNA (dsDNA) molecules labeled at both ends are commonly produced by annealing

34 ts and lengths of up to 75 A, have been spin-labeled at both ends with stable nitroxide TEMPO radical

35 ent label at the N-terminus, and another one labeled at both ends.

36 6-position and approximately 4-fold for DHO labeled at both the 5- and 6-positions.

37 t the 6-position, and about 6-7-fold for DHO labeled at both the 5- and 6-positions.

38 e TATA box binding protein was photoaffinity labeled at bp -26/-21 with nucleotide analogs containing

39 it of TFIIIB (Mr = 90 kDa) was photoaffinity labeled at bps -26/-21 with DNA containing a approximate

40 s detected when histidine specifically (13)C-labeled at C-2 of the imidazole ring was used, providing

41 3 and D-talose 8 selectively (13)C- and (2)H-labeled at C1 and H1.

42 The stearate spin-labeled at C5 has the highest affinity for the lipoxygen

43 (111)In- and (90)Y-ibritumomab tiuxetan are labeled at commercial radiopharmacies and delivered for

44 eria toxin transmembrane (T) domain was spin-labeled at consecutive residues in a helical segment, TH

45 GluR4-receptor subunits labeled at corticothalamic synapses on RTN neurons outnu

46 skinned psoas fibers reconstituted with sTnC labeled at Cys 98 with 5'ATR, dichroism was maximal duri

47 cdb3 was labeled at Cys-201 with fluorescein maleimide.

48 ence of a mutant Galphat (Chi6b) selectively labeled at Cys-210.

49 The catalytic domain of the myosin head was labeled at Cys-707 with indane dione spin label; the reg

50 A genetically engineered cardiac TnC mutant labeled at Cys-84 with tetramethylrhodamine-5-iodoacetam

51 ne mutant of the protein (C35S) specifically labeled at Cys-84 with the fluorescent probe 2(-)[4'-(io

52 zard myosin regulatory light chain (RLC) was labeled at Cys108 with either the 5- or the 6-isomer of

53 The essential light chain was labeled at Cys177 with the indanedione spin-label follow

54 te binding protein (PBP) and the same mutant labeled at Cys197 with N-[2-(1-maleimidyl)ethyl]-7-(diet

55 ingly, RTryp complexes containing alpha(1)PI labeled at Cys232 with a cationic fluorophore display tw

56 MPO leads to an inactive enzyme that is spin-labeled at cys273.

57 Chi6a labeled at Cys347 also showed an AlF4--dependent increas

58 conformation and dynamics of actin filaments labeled at Cys374 with erythrosin-iodoacetemide (ErIA),

59 ds (S1) on the microsecond dynamics of actin labeled at Cys374 with erythrosine iodoacetamide.

60 led by EPR studies on hCB(1)(T377-E416) spin-labeled at Cys382 and reconstituted into the phospholipi

61 efolding kinetics of iso-1-cytochrome c spin-labeled at Cysteine 102.

62 etected by fluorescence spectroscopy of gHgL labeled at cysteine 153 at the domain I-domain II interf

63 ght chain and re-addition of the light chain labeled at cysteine-108 with the 6-isomer of iodoacetami

64 By all physical evidence, the protein labeled at cysteine102 folded, but the spin probe in thi

65 bled from DNA fragments such that a chain is labeled at designated spots with covalently attached flu

66 arison of REDOR spectra on samples that were labeled at different residue positions suggests that the

67 measurements between eight Rep mutants donor-labeled at different residues and pdDNA acceptor-labeled

68 ithelial cells undergoing DNA synthesis were labeled at discrete time points following abrasion.

69 des from bovine fibrinogen were fluorescence labeled at each branch specifically for conformational s

70 emical shifts were carried out in constructs labeled at either Ala-6 or Ala-15.

71 Caldesmon was labeled at either Cys-153 in the NH2 domain or Cys-580 i

72 Caldesmon was labeled at either Cys-153 in the NH2-terminal domain or

73 ned by spin dipolar quenching in six samples labeled at either the cytoplasmic or extracellular ends

74 that were (13)CO-labeled at Ala-14 and (15)N-labeled at either Val-2, Gly-3, Ile-4, or Gly-5.

75 d identical experiments on both myosins spin-labeled at equivalent sites.

76 m DNA molecule that is simultaneously methyl-labeled at five sites, showing that high-quality (13)C-(

77 nce: KKITLIIFG(79)VMAGVIGTILLISWG(94)IKK was labeled at G(79) and G(94) with (13)C=(16)O or (13)C=(18

78 Q(2)A-alpha(2)AP was also labeled at Gln(21) > Gln(419) > Gln(447), but became cro

79 Actin labeled at Gln-41 with dansyl ethylenediamine (DED) via

80 atidylinositol-specific phospholipase C spin-labeled at H82C, a position near the active site of the

81 In contrast, when the right SHF was labeled at HH18, the fluorescence was limited to the cau

82 their bipotential progenitors) are heritably labeled at high efficiency with yellow fluorescent prote

83 n of 1.9 microM, whereas the 60-kDa band was labeled at higher concentrations.

84 ent base, 2-aminopurine (2-AP), and dT(pT)15 labeled at its 3'-end with fluorescein (3'-F-dT(pT)15).

85 fied free target protein can be specifically labeled at its C-terminus.

86 fluorescence enhancement of a reference DNA labeled at its end with a Cy3 fluorophore.

87 tes resolution, to observe a growing peptide labeled at its N terminus with the fluorophore tetrameth

88 ldihydrotestosterone, a steroid that is spin-labeled at its solvent-exposed end, induced the selectiv

89 region) also project to both tissues but are labeled at later times.

90 More spinal and brainstem neurons were labeled at longer survival times.

91 Although occasional brainstem nuclei were labeled at low levels by embryonic day 18, the majority

92 orporation and alphaCys-192 and alphaTyr-198 labeled at lower efficiency.

93 NMR measurements on OspA specifically 15N-labeled at Lys residues identified the locations of the

94 To accomplish this goal, PLB was labeled at Lys-3 in the cytoplasmic domain, with two dif

95 nding with three well-characterized proteins labeled at lysine residues: calmodulin (CaM), maltose-bi

96 at Ser-301, and on the (-)-side, beta3M1 was labeled at Met-227.

97 Neuronal clones in the ferret labeled at middle to late neurogenesis (embryonic day 33

98 aromyces cerevisiae iso-1 ferricytochrome c (labeled at mutant Cys residues 4, 39, 50, 66, and 99) by

99 r classification of research participants is labeled AT(N) for amyloid, tau, and neurodegeneration bi

100 genomic restriction fragments that were end-labeled at NotI cleavage sites.

101 The fluorogenic peptide was labeled at one end with a UV/blue fluorophore (N-methyla

102 scence decays of a series of oligoquinolines labeled at one end with an oligo(phenylenevinylene) dye

103 Arp2/3 actin nucleation complex selectively labeled at one subunit and obtained (1)H/(13)C-HSQC spec

104 labeled, ~37,800 unlabeled) and SL (~44,100 labeled) at patch-level diagnoses (area under the curve

105 X-MS experiments using unstructured peptides labeled at pD 4.0 under crowded and uncrowded conditions

106 For nonreduced preparation, rMAbs are labeled at pH 6.5 with a dye-to-protein (D/P) molar rati

107 For reduced preparation, rMAbs are labeled at pH 9.3 with a D/P molar ratio of 10:1, which

108 ant near 300 nM was determined for a variant labeled at position 12, in the N-terminal domain.

109 ssociation constants near 30 nM for variants labeled at position 33, in the N-terminal domain, and po

110 ualifying differences seen with the receptor labeled at position 417, which had motion between the in

111 e particularly illustrative for the receptor labeled at position 530, which had motion between the fa

112 [(11)C]PD153035 labeled at position 6 was metabolized extensively in viv

113 domonas reinhardtii (CrChR2) was selectively labeled at position Cys-79 at the end of the first cytop

114 ycosides into the emissive A-site construct, labeled at position U1406, shows a decrease in donor emi

115 The peptide is 13Calpha-labeled at position V9(a) and results are compared with

116 We found that the fibrils labeled at positions 127, 144, 196, and 230 displayed co

117 for the alkaline phosphatase signal peptide labeled at residue 22 or 2, respectively, with SecA, and

118 unfolding, whereas the unfolding of fibrils labeled at residue 88 was non-cooperative.

119 , the tracking of translation with ribosomes labeled at rRNA helices h44 and H101 showed a lack of sp

120 eukocyte antigen (HLA)-DR A and B genes were labeled at saturation with a univalent probe consisting

121 employed to detect local motions of Galphai1 labeled at selected sites with Alexa 488 (C5) fluorescen

122 eptors were expressed in Xenopus oocytes and labeled at selected sites with environment-sensitive flu

123 Fibers were extensively and predominantly labeled at SH1 (Cys-707) of the myosin heavy chain with

124 Spectra of arrestin spin-labeled at site 267 were recorded at room temperature as

125 Two separate derivatives, labeled at sites 44 and 69, were analyzed.

126 heW, and an engineered single-chain receptor labeled at six different sites allow docking of the rece

127 ters formed in the presence of symmetric PCs labeled at sn-2.

128 It was labeled at specific activities of 1.1-2.7 mCi/mg using N

129 ole-dipole couplings in samples that are 13C-labeled at specific sites and two-dimensional 15N-13C an

130 ve electron paramagnetic resonance of myosin labeled at specific sites with BSLs in oriented muscle f

131 We find that progenitor cells labeled at stage 19-22 can give rise to multiple cell ty

132 We show that when labeled at tail somite 15-17 stages, corresponding to 11

133 When labeled at tail somite 18-20 stages, corresponding to 11

134 The S179C variant of GlnBP was labeled at the -SH and N-terminal positions with acrylod

135 mide gel electrophoresis of samples that are labeled at the 3'- or 5'-terminus with (32)P.

136 le while the other nucleic acid fragment was labeled at the 3'-end by a dansyl molecule prone to be i

137 ontaining mRNA in total RNA was detected and labeled at the 3(')-terminal on a poly(T) template.

138 ically, the aptamer A1-949 was fluorescently labeled at the 5' end and hybridized with a short quench

139 In these studies, we used DNA substrates labeled at the 5' end of the template strand and the 5'

140 The oligodeoxyribonucleotide was labeled at the 5' end with 32P and at the 3' end with a

141 t oligonucleotide probes that are covalently labeled at the 5' end with a fluorophore and at the 3' e

142 d by an oligonucleotide "tail" fluorescently labeled at the 5' end.

143 amics of a 20-mer HIV-1 RNA stem loop 3 spin-labeled at the 5' position were probed in the nanosecond

144 ling reduction and were about 3-fold for DHO labeled at the 5-position, about 4-fold for DHO labeled

145 At pH 8.5, the KIEs observed for DHO labeled at the 5-position, the 6-position, and the 5- an

146 eled at the 5-position, about 4-fold for DHO labeled at the 6-position, and about 6-7-fold for DHO la

147 As occurred in protease complexes with crmAs labeled at the 68 and 261 positions, but not the P1' pos

148 reinhardtii, to yield the enzyme selectively labeled at the [2Fe]H subcluster.

149 Further studies with Pm labeled at the active site with 2-anilinonaphthalene-6-s

150 deletion mutant (SKDeltaK414) binding to Pm labeled at the active site with 5-fluorescein ([5F]FFR-P

151 (mAbs), two of which block EPCR/Fl-APC (APC labeled at the active site with fluorescein) interaction

152 dynamic exchange was detected with pre-mRNA labeled at the AG dinucleotide of the 3' splice site.

153 otope effect was determined for benzaldehyde labeled at the aldehyde position and found to be small (

154 pG sites in the (GCC)n hairpins that are 15N-labeled at the amino (N4) groups of specific cytosine ba

155 of replicons in replicon clusters that were labeled at the beginning of one S phase were also labele

156 ed at the beginning of one S phase were also labeled at the beginning of the next.

157 opsin that was regenerated with retinal (2)H-labeled at the C(5), C(9), or C(13) methyl groups by tot

158 Often the nicotinamide ring is labeled at the C-4 position which is directly involved i

159 was regenerated using retinal that was (2)H-labeled at the C5, C9, or C13 methyl groups and was reco

160 (Pg), which are specifically inactivated and labeled at the catalytic site have been prepared and cha

161 d to create novel analogs of ProT covalently labeled at the catalytic site with fluorescence probes.

162 The half-life of Env labeled at the cell surface was markedly reduced in the

163 ional COOH-terminal residues, GMLC, and then labeled at the COOH-terminal cysteine with fluorescein 5

164 aled by both the failure of veg1 descendants labeled at the eighth equatorial division to segregate p

165 m)Tc-HYNIC-annexin V showed that the protein labeled at the endogenous chelation site had the same or

166 Tritiated adenosylcobalamin, labeled at the exchangeable position, has been used to i

167 sonance energy transfer (FRET), using lipids labeled at the headgroup with pyrene (Py) as donors and

168 und 6b was demonstrated to be >/=95% tritium-labeled at the imine position by NMR spectroscopy, and t

169 led at different residues and pdDNA acceptor-labeled at the junction were conducted at each of the fo

170 -time dynamic coupling between the ribosome, labeled at the L1 stalk, and transfer RNA (tRNA).

171 Transgenic mice labeled at the M71 odorant receptor (specifically activa

172 Each peptide was specifically labeled at the MAG3 chelation sites at ambient temperatu

173 L-AE (S = (1)/(2)) in the presence of AdoMet labeled at the methyl position with either (2)H or (13)C

174 nstructs of Galphai/o subunits fluorescently labeled at the N terminus (GAP43-CFP-Galphai/o) seem to

175 In addition, using active terminases labeled at the N- and C-terminal ends with a single dye

176 Furthermore, we introduce LE labeled at the N-terminus with a metal-chelating agent,

177 The resulting protein was site-specifically labeled at the N-terminus with fluorescein and a cyclic

178 ide (ODN) containing a cis-syn thymine dimer labeled at the N3 of both T's with 15N by two efficient

179 When crushed optic nerve was retrogradely labeled at the nerve stump, no labeling of retinal neuro

180 ivity was also investigated on cellopentaose labeled at the nonreducing end with 14C, and cellooligos

181 results in the surface of DNA being randomly labeled at the phosphorothioate sites with this protein-

182 fate chains were purified from CHO cells and labeled at the reducing end with [3H]NaBH4.

183 These standards were isotopically labeled at the reducing terminal GlcNAc, which allowed u

184 Muscle was labeled at the regulatory domain by replacing native ess

185 Studies with this substrate labeled at the RNA 3' end showed that Y181C is no more l

186 ions of the molecule, except the C-terminus, labeled at the same nine axial positions in each half A-

187 ed molecules, and thus many molecules can be labeled at the same time and within the point spread fun

188 dione spin label; the regulatory domain was labeled at the single cysteine residue of the essential

189 C102T variant of yeast iso-1-cytochrome c is labeled at the single cysteine residue on the back surfa

190 102T variant of yeast iso-1-cytochrome c was labeled at the single cysteine residue with a tris (bipy

191 With this method, peptides get labeled at their C-terminus, at Asp and Glu residues, an

192 rminals of B-type horizontal cells were also labeled at their contacts with rod spherules.

193 s of growth factors that were quantitatively labeled at their N-termini and retained their binding ch

194 pproach, surface bound peptides, selectively labeled at their N-termini with a positive charge-bearin

195 fer (FRET) experiments conducted on peptides labeled at their N-termini with either tetramethylrhodam

196 are based on probe oligonucleotides that are labeled at their opposite termini with Tb and a fluoresc

197 Of 205 GAD67-ir cells labeled at these sites, 74% exhibited immunoreactivity f

198 data on ligand-free GlnBP, paramagnetically labeled at two sites (one at a time), could be appropria