ライフサイエンスコーパス: labor-intensive

1 cell counts and differentials of sputum are labor intensive.

2 Surveillance for VAP is subjective and labor intensive.

3 d mass spectrometry, which are expensive and labor intensive.

4 lieved to be highly accurate; however, it is labor intensive.

5 ome sequencing is still costly, lengthy, and labor intensive.

6 but, for the most part, they are costly and labor intensive.

7 most of these methods are time consuming and labor intensive.

8 sm, because mapping these networks is highly labor intensive.

9 This process is both time-consuming and labor intensive.

10 LTR retrotransposons in genome databases are labor intensive.

11 has the advantage of being simpler and less labor intensive.

12 nrespondents were successful but were highly labor intensive.

13 r, the generation of such maps is costly and labor intensive.

14 ull-length cDNA clone can be highly time and labor intensive.

15 in pathology, despite being highly time and labor intensive.

16 oculture assay is however time-consuming and labor intensive.

17 making alloy development time consuming and labor intensive.

18 numbers of samples are still highly cost and labor intensive.

19 reas classical ASO-PCR is time-consuming and labor intensive.

20 e post-screen validation process is time and labor intensive.

21 es such as surgeries both time consuming and labor intensive.

22 ; however, their production is expensive and labor-intensive.

23 n are annotated manually, which is time- and labor-intensive.

24 ng bacterial cultures are time-consuming and labor-intensive.

25 ermining hVISA, but it is time-consuming and labor-intensive.

26 methods require purified proteins and/or are labor-intensive.

27 ther culturing combinations and is the least labor-intensive.

28 cing approaches are prohibitively costly and labor-intensive.

29 oylation sites is usually time-consuming and labor-intensive.

30 with these mutations are often difficult and labor-intensive.

31 rocessing of large amounts of data much less labor-intensive.

32 Many investigators regard SBAs as time- and labor-intensive.

33 C-peptide-binding assays that are costly and labor-intensive.

34 of IFA slides, which was both subjective and labor-intensive.

35 rting tether which can be time-consuming and labor-intensive.

36 n sequestration and that briquette making is labor-intensive.

37 scale due to several limitations, including labor-intensive agar plating and colony selection method

38 an entirely automatic fashion, thus avoiding labor-intensive analyses and potential intra- or interob

39 and liquid-liquid extraction (LLE) steps are labor intensive and are thus not practical for high-thro

40 for cell types of interest, but are costly, labor intensive and can limit investigation of important

41 tional methods, this technology is much less labor intensive and can provide accurate and reliable re

42 modulate these phenotypes in human cells is labor intensive and challenging to scale.

43 erefore, human interventions, which are both labor intensive and error prone, have to be performed.

44 he need for radioactive isotopes and is less labor intensive and faster than the alternative PAGE wit

45 nce of such cells often proves to be costly, labor intensive and ineffective.

46 he axonal projections of selected neurons is labor intensive and inherently limited by currently avai

47 t allow remote control of neurons are either labor intensive and invasive or indirectly coupled to ne

48 The method is less labor intensive and label-free with ease of monitoring t

49 r regulatory motifs within a promoter can be labor intensive and may miss redundant, unprecedented or

50 entation and has the advantage of being less labor intensive and more repeatable.

51 Current approaches are labor intensive and mostly limited to elucidating high-a

52 Traditional potency evaluations tend to be labor intensive and often are not precise.

53 anually collect relevant materials is rather labor intensive and often incomplete due to resource con

54 relations between IR and NMR signals and are labor intensive and possibly ambiguous.

55 side-chain resonance assignment, however, is labor intensive and prone to error.

56 ved less attention as these screens are more labor intensive and require extensive resources.

57 ional single-cell data are often subjective, labor intensive and require prior knowledge of the biolo

58 However, it is labor intensive and requires large volumes of human milk

59 In addition, it is less labor intensive and requires less DNA than previous meth

60 ield of senescence/immortalization, but were labor intensive and the results were somewhat limited.

61 the current Sanger method is too expensive, labor intensive and time consuming to accomplish medical

62 er, the existing technologies are expensive, labor intensive and time consuming, posing significant l

63 ression screening; however, this approach is labor intensive and time consuming.

64 ts a logistical challenge, as the process is labor intensive and time consuming.

65 edical records review; however, this is very labor intensive and vulnerable to misclassification.

66 TFs makes genome-wide profiling for them all labor-intensive and costly.

67 ance method, this technique is prohibitively labor-intensive and expensive, requiring repeated measur

68 '-is based on imaging methods that are slow, labor-intensive and expensive.

69 However, they are usually time-consuming, labor-intensive and expensive.

70 rmining ambient redox potential in cells are labor-intensive and generally require destruction of tis

71 detection method is more sensitive and less labor-intensive and has a more rapid turnaround time.

72 rometry-based proteomics remains subjective, labor-intensive and inconsistent between laboratories.

73 olation of EVs, it is highly time-consuming, labor-intensive and instrument-dependent for both resear

74 tion has been developed, but it is typically labor-intensive and low-throughput.

75 he needs of continual monitoring as they are labor-intensive and not easily integrable with low-volum

76 ions of these factors make immunoassays more labor-intensive and often challenging to validate in sup

77 rent batch cultivation methods are time- and labor-intensive and often fail to consider sophisticated

78 s for intraoperative histology are time- and labor-intensive and often introduce artifact that limit

79 haracterization of this species is time- and labor-intensive and often leads to misidentification in

80 cificity and multiplexing capability, can be labor-intensive and prone to human error, making them un

81 thods of assessing myocardial infiltrate are labor-intensive and provide data that are difficult to q

82 However, these techniques are relatively labor-intensive and require a significant amount of trai

83 Microscopy is, however, labor-intensive and requires a skilled technologist.

84 SNPs; however, the scoring of these SNPs is labor-intensive and requires a substantial amount of aut

85 ed to automate this task which at present is labor-intensive and requires considerable informatics an

86 s, demanding peptide enrichment which can be labor-intensive and requires large amount of material.

87 One drawback of these screens is the labor-intensive and sometimes inconclusive process of ma

88 imately rely on manual curation and are thus labor-intensive and subjective.

89 same order of magnitude for that of the more labor-intensive and time-consuming cell-assay technique,

90 rentiation of Cryptosporidium species, it is labor-intensive and time-consuming compared with methods

91 vides a cost-effective solution to eliminate labor-intensive and time-consuming fluidic handling step

92 vides a cost-effective solution to eliminate labor-intensive and time-consuming fluidic handling step

93 e regulation of NPQ have relied primarily on labor-intensive and time-consuming generation of stable

94 was produced in 24 hours, compared with more labor-intensive and time-consuming hybridoma or recombin

95 al bioprocessing has traditionally relied on labor-intensive and time-consuming immunoassays.

96 Large-scale sample collection is a labor-intensive and time-consuming process; the informat

97 nd individual strain identification, it is a labor-intensive and time-consuming technique.

98 g emerging CTL epitope mutations rely on the labor-intensive and time-consuming techniques of virus p

99 screening process can reduce the burden of a labor-intensive and time-consuming traditional literatur

100 nalysis of the resulting fractions, which is labor-intensive and time-consuming.

101 unoassays for IFN-gamma, this assay is still labor-intensive and time-consuming.

102 However, it is labor-intensive and time-consuming.

103 by exponential enrichment (SELEX)) are often labor-intensive and time-consuming.

104 arge amounts of material for analysis and is labor-intensive and time-consuming.

105 andard histologic methods is time consuming, labor intensive, and dependent upon investigators' exper

106 duction neutralization test (PRNT), is slow, labor intensive, and difficult to validate and transfer.

107 a small blood volume; (iii) is faster, less labor intensive, and less expensive; and (iv) can be rea

108 id nuclear scans, which are costly, time and labor intensive, and often require conscious sedation by

109 assay can be performed in 4 h, is much less labor intensive, and showed less cross-reactivity with r

110 tional saturation mutagenesis approaches are labor intensive, and the resulting TCRs may be cross-rea

111 ants by flanking sequence analysis is highly labor intensive, and therefore, libraries that do exist

112 personalized DC immunization is too costly, labor intensive, and time-consuming for large-scale vacc

113 The method is not labor intensive, and, because pretreatment of the urine

114 al issues; notably, they are time-consuming, labor-intensive, and are characterized by relatively low

115 , microinjection is a technically demanding, labor-intensive, and costly procedure with poor embryo v

116 f the UHPLC-HRAM-MS data is a very daunting, labor-intensive, and expertise-dependent process.

117 assays usually involves manual counting, is labor-intensive, and is subject to bias.

118 taining; however, these approaches are slow, labor-intensive, and often fail to enable further geneti

119 onal promoter-repressor sets is complicated, labor-intensive, and often results in unanticipated cros

120 ols for the diagnosis of OSA in children are labor-intensive, and onerous, and remain unvalidated.

121 are commonly applied but are time-consuming, labor-intensive, and poorly reproducible.

122 Conventional serological methods are costly, labor-intensive, and prone to misidentification, while c

123 ns, such processes are relatively expensive, labor-intensive, and require bulky and costly equipment.

124 d-standard" viral outgrowth assay is costly, labor-intensive, and requires large numbers of cells.

125 tect Mycobacterium tuberculosis are complex, labor-intensive, and technically challenging.

126 PFGE is labor-intensive, and the results are difficult to analyz

127 alian sequences will not receive the kind of labor-intensive annotation efforts that are currently be

128 quently, diagnosis relies entirely on PCR, a labor-intensive approach that requires highly skilled pe

129 ng BAC clones, generated by an expensive and labor-intensive approach.

130 ly automated, performs similarly to previous labor intensive approaches, provides consistent results

131 These labor-intensive approaches have struggled to keep pace w

132 field-conditions is hindered by traditional labor-intensive approaches that are prone to taxonomic a

133 ring demographics may effectively complement labor-intensive approaches, with the potential to measur

134 t present, these conversions remain time and labor-intensive as they require embryos to be injected w

135 ide triphosphates (dNTPs) employ reagent and labor-intensive assays utilizing radioisotopes in DNA po

136 uperinfection have involved a combination of labor-intensive assays with various rates of success.

137 Previously, expensive and labor-intensive BAC-based techniques were used to sequen

138 However, sequencing is labor intensive because it requires previous amplificati

139 hway, experimental studies generally require labor-intensive biochemical techniques.

140 mendous task of automating the important yet labor-intensive biocuration effort.

141 residue positions for probe incorporation in labor-intensive biophysical experiments such as chemical

142 SNPs, and the "curves" method, which is more labor intensive but also slightly more accurate.

143 a medical center, rapid diagnosis by DFA was labor intensive but was 98.7% sensitive and 100% specifi

144 The procedures for this are labor-intensive but important for the identification of

145 Only inaccurate and labor-intensive cell-free biochemical assays are current

146 ethod can be time-consuming because multiple labor-intensive centrifugations and washes with organic

147 ss monitoring method and can replace several labor-intensive chromatographic and colorimetric methods

148 Our approach replaces labor-intensive coating evaluation steps with an automat

149 The time-consuming and labor intensive compound separation and purification pro

150 nalysis of HIV diversity, but this method is labor-intensive, costly, and requires complex protocols

151 d for product identification can be time and labor intensive, creating a need for quick, inexpensive

152 olayer model has several drawbacks including labor-intensive culture process, unphysiological growth

153 tgun sequencing of bacterial genomes remains labor-intensive, despite advances in sequencing technolo

154 GPCR target of interest has necessitated the labor-intensive development of cell lines stably express

155 ar on the American Community Survey (ACS), a labor-intensive door-to-door study that measures statist

156 agnification near-field (HN) images that are labor intensive due to a requirement for manual image se

157 hese compounds can progress to expensive and labor-intensive efficacy studies in mice, creating a 'bo

158 e use of the ViBE Bioanalyzer eliminates the labor-intensive effort of Western blot analysis and is d

159 in in human serum while also eliminating the labor-intensive efforts of Western blot analysis and is

160 ration of genetic and physical maps involves labor-intensive empirical experiments.

161 arch programs are currently involved in this labor-intensive endeavor.

162 f pairing antibodies is often cumbersome and labor-intensive even with the use of designed peptide-sp

163 r tubulin polymerization are low throughput, labor intensive, expensive, or make their assessment in

164 te to quantify 5-HT(2C) receptor editing are labor-intensive, expensive and provide limited informati

165 ancer development, these models are much too labor-intensive, expensive, and slow to perform the exte

166 ssay can be a viable alternative to the more labor-intensive filtration and centrifugation methods.

167 t methods of detection are too expensive and labor-intensive for routine detection of these organisms

168 Although the measurements are labor intensive, FRET in liposomes can be measured accur

169 These methods are labor-intensive, generate random breakpoints and result

170 However, TEM is labor intensive, has a long turnaround time, and uses eq

171 Labor-intensive homogenization or sonication of whole or

172 easurements are necessary but also extremely labor intensive if manual flux chamber based methods are

173 These tasks may be labor intensive if performed manually.

174 arsing problems that have made such analyses labor-intensive in the past.

175 This approach bypasses labor-intensive in vitro mutagenesis and samples a large

176 ncerns related to integration included being labor intensive, inadequate staff to implement, inadequa

177 However, these methods are labor intensive, incompatible with most other histochemi

178 ridiosis is likely underestimated due to the labor-intensive, insensitive, and nonspecific clinical l

179 However, this method is time-consuming and labor-intensive, is sensitive to virus aggregation and a

180 However, SELEX is a lengthy, labor-intensive, iterative process requiring multiple ro

181 and abiotic stresses are time-consuming and labor-intensive limiting the ability to dissect the gene

182 ges or hemilineages unambiguously other than labor-intensive lineage-tracing methods.

183 d extraction is an attractive alternative to labor-intensive manual methods.

184 s for surgery to overcome time-consuming and labor-intensive manual processes.

185 testing can often be performed only by using labor-intensive, manual dilution methods and lies outsid

186 isotherm linearity, thereby enabling a less labor intensive means to generate the extensive data set

187 is as accurate and effective as traditional labor-intensive measures of flowering time, height, biom

188 s a rapid-throughput, reproducible, and less labor-intensive method than RT-PCR for quantifying cellu

189 Here, we report a rapid, less labor-intensive method that can quantitatively measure M

190 However, significant tissue requirements and labor-intensive methodology have limited the large-scale

191 onditional knockout mice are generated using labor-intensive methods of homologous recombination in e

192 plasma and urine are generally determined by labor-intensive methods requiring sample purification by

193 Other methods of detection rely on labor-intensive, microscopy-based techniques.

194 ironmental isolates prior to conducting more labor-intensive molecular typing methods.

195 r experiments were thus possible despite the labor-intensive nature of inoculating plants with bacter

196 for identifying regulatory elements, but the labor-intensive nature of this technique has limited its

197 ment of internal organs, often necessitating labor-intensive nonlinear mapping that may not converge

198 ing DNA repair capacity (DRC) are relatively labor intensive, often indirect, and usually limited to

199 for the detection of IGH translocations are labor intensive, often require viable cells, and are bia

200 mpatibility for automated data analysis, and labor-intensive operations.

201 ngle sample are typically time-consuming and labor intensive or require large sample sizes to split f

202 rus per cell culture dish than the much more labor-intensive organotypic culture.

203 nologically intensive treatments rather than labor-intensive palliative care.

204 e determination typically involves time- and labor-intensive PCR-based amplification and cloning meth

205 physical genome maps obviating the need for labor-intensive physical genome mapping.

206 However, sample preparation remains a labor-intensive portion of the procedure.

207 developed a high-throughput approach to the labor-intensive problems of DNA cyclization, which we us

208 Such a delayed and labor-intensive procedure creates a barrier to automatio

209 This is a labor-intensive procedure, prone to human error and subj

210 sitivity, complexity, and time-consuming and labor-intensive procedure.

211 However, these labor-intensive procedures can be avoided when mass spec

212 ologID, a Web application that automates the labor-intensive procedures of gene orthology determinati

213 o mention easy-to-use detection to eliminate labor-intensive procedures.

214 in mass spectrometry data analysis and is a labor intensive process for many proteomics laboratories

215 This labor-intensive process could be made easier by automati

216 -specific labeling of nonnative cysteines, a labor-intensive process occasionally resulting in dimini

217 knowledge bases manually compiled through a labor-intensive process or automatically derived using s

218 t useful for the desired analysis; this is a labor-intensive process that is often impossible or unfe

219 tion of Brucella can be a time-consuming and labor-intensive process that places personnel at risk fo

220 screening of libraries is a time-consuming, labor-intensive process that sometimes fails to yield th

221 ression profiles can be a time-consuming and labor-intensive process with current one-at-a-time techn

222 These high-throughput but labor-intensive projects serve as an ideal way to introd

223 athology and immunohistochemistry, which are labor-intensive, prone to sampling bias and technical va

224 omprehensive assessment of methylated sites, labor-intensive protocols, and/or the need for expensive

225 ained by limitations of techniques that were labor-intensive, provided coarse levels of resolution, o

226 has less discriminatory power than the more labor-intensive pulsed-field gel electrophoresis (PFGE)

227 directly in the flask without dangerous and labor-intensive purification operations or exposure of t

228 ghput assays instead of using the costly and labor-intensive radioactive ligands.

229 ously were seen only by using the costly and labor-intensive radioactive tDPPO assay.

230 mazonian land use, which did not necessitate labor-intensive rainforest clearance for earthwork const

231 ecules in a manner that is rapid, cheap, non-labor-intensive, readily automated, and without a requir

232 ortical thickness from neuroimaging data are labor intensive, requiring several days of effort by a t

233 sequences, but it currently is hampered by a labor-intensive sample preparation process designed to i

234 of large populations of nematodes, requiring labor-intensive sample preparation that considerably lim

235 dvantages as ease of operation, exclusion of labor-intensive sample pretreatment processes, rapid ana

236 The method is simple and fast and is not labor intensive (sample preparation and analysis can be

237 Disadvantages of the current assay include labor intensive screening and interpretative challenges

238 or most of the genes previously obtained by labor-intensive screening for pattern-defective mutants.

239 We conclude that, despite the labor-intensive search for existing guidelines, a de nov

240 Highly labor-intensive serial sectioning studies have demonstra

241 agreement with population sequencing and the labor-intensive single-genome sequencing method.

242 ent to manual analysis, as being subjective, labor-intensive, slow, and often incapable of showing th

243 n invented to eliminate a time-consuming and labor-intensive step in preparation of in vivo study sam

244 Target construct generation, the first labor-intensive step in this process, requires the manip

245 ormed on cell lysates, which circumvents the labor-intensive step of DNA extraction, and rely on the

246 a liquid handling platform, to automate this labor-intensive step.

247 and infectivity can circumvent the time and labor-intensive steps associated with viral antigen-base

248 enome assembly--which are time-consuming and labor-intensive steps.

249 e and limited by multiple time-consuming and labor-intensive steps.

250 uptake and depuration rate constants require labor intensive studies with large numbers of organisms.

251 tability in dust before designing costly and labor-intensive studies of allergen exposure and health

252 trast to traditional methods which are often labor-intensive, subjective to bias and do not allow fur

253 of outbreaks and nosocomial transmission are labor-intensive, subjective, or insufficiently discrimin

254 are requires multidisciplinary coordination, labor-intensive support for critically ill patients, and

255 es, but their preparation can be hampered by labor-intensive synthesis of required starting materials

256 However, culture is labor-intensive, takes several days to weeks for growth,

257 nsequences of individual mutations remains a labor-intensive task.

258 range of investigations is a challenging and labor-intensive task.

259 f alpha-amino acids as an alternative to the labor-intensive technique of chromatography.

260 Unfortunately, IP is a labor-intensive technique, is difficult to perform in pa

261 molecules at the species level has required labor-intensive techniques.

262 sported to a central laboratory for slow and labor intensive tests.

263 This approach is rapid and less labor intensive than are traditional methods, without di

264 or platform is significantly faster and less labor intensive than commonly available technologies, ma

265 Although more labor intensive than CPC extraction, the protocol is mor

266 the DiversiLab system was considerably less labor intensive than PFGE and provided results in less t

267 pholipase C-gamma1) antibody, making it less labor intensive than previously described methods for us

268 ventilator-associated pneumonia, it is more labor intensive than the calibrated loop technique.

269 fold transplantation is more complicated and labor-intensive than cell suspensions, it affords de nov

270 d is accurate, cheaper, more rapid, and less labor-intensive than DNA sequencing.

271 It is less labor-intensive than previously described assays and is

272 The method presented here is far less labor-intensive than the univariate methods attempted to

273 This method is less labor-intensive than those that require isolation and am

274 he generation of these maps is iterative and labor intensive; therefore, we developed a series of com

275 hydrolysis protocol which is cumbersome and labor intensive, this new protocol is ideal for high-thr

276 ay is sensitive and accurate, it is slow and labor-intensive; thus, it precludes the simultaneous scr

277 such screens, the current procedure remains labor intensive, time consuming, and costly.

278 ment of critical data is somewhat impeded by labor-intensive, time- consuming processes that are requ

279 ridization (FISH) and have consequently been labor-intensive, time-consuming and restricted to the lo

280 However, it is a labor-intensive, time-consuming hybridization process an

281 Surgery is a labor-intensive, time-consuming profession.

282 The process is labor-intensive, time-consuming, and expensive.

283 ing test because it is widely perceived as a labor-intensive, time-consuming, and technically demandi

284 use high-magnification DFM images, which are labor intensive to acquire and subject to operator bias.

285 been impeded by methods that are either too labor intensive to allow large-scale studies or not suff

286 echnology is too costly, time consuming, and labor intensive to meet this ongoing demand.

287 sis (FSA), are destructive and too time- and labor-intensive to be practical or economical.

288 ption to BC because it is time-consuming and labor-intensive to obtain isotherms on soot and other BC

289 niques that are much more time-consuming and labor-intensive to perform.

290 in vivo have typically relied on costly and labor-intensive transgenic strategies in mice.

291 ion mapping has proven to be a difficult and labor-intensive undertaking, usually requiring years to

292 to detect these modifications are expensive, labor-intensive, unfeasible in some contexts and leave a

293 Such analyses are time-consuming and labor-intensive using conventional means.

294 es in the cell culture is time-consuming and labor-intensive, usually involving a purification step t

295 site-year combinations mimicking common, but labor-intensive, water-sampling regimes (e.g., time-inte

296 These methods are labor-intensive when measuring methane emissions from a

297 l VI assessments are often time-, cost-, and labor-intensive; whereas traditional subsurface methods

298 diagnostic method can be time consuming and labor intensive, which is not practical for on-site diag

299 op molecular diagnosis is time-consuming and labor-intensive, which limits the treatment efficiency e

300 Some of these tests are labor-intensive, while others require little labor, and