ライフサイエンスコーパス: lactate dehydrogenase

1 aminotransferase, alanine aminotransferase, lactate dehydrogenase).

2 lveolar lavage neutrophils, eosinophils, and lactate dehydrogenase.

3 tage disease, B symptoms, and elevated serum lactate dehydrogenase.

4 aphic analysis of allosterically inhibited L-lactate dehydrogenase.

5 er than three organ sites and lower baseline lactate dehydrogenase.

6 zyme for the study of reaction landscapes is lactate dehydrogenase.

7 autolysis of cells using a cytosolic enzyme lactate dehydrogenase.

8 Studies with isolated lactate dehydrogenase-1 and malate dehydrogenase-2 revea

9 rt 2.8-A- and 1.8-A-resolution structures of lactate dehydrogenase (145 kDa) and glutamate dehydrogen

10 testinal-type fatty acid-binding protein and lactate dehydrogenase (3427+/-236.8 U/L for I/R, 1190.5+

11 activity in vitro, with lower expression of lactate dehydrogenase 5, hypoxia-inducible factor 1 alph

12 ents who received D + T with baseline normal lactate dehydrogenase (5 years, 45%) and normal lactate

13 gen-6 (odds ratio [95% CI], 6.1 [3.0-12.1]), lactate dehydrogenase (5.7 [1.7-19.1]), soluble receptor

14 nd determined the effects of lactic acid and lactate dehydrogenase-5 (LDH5) overexpression on myofibr

15 ase (34.3 +/- 16.6 vs 24.5 +/- 16.8U/L), and lactate dehydrogenase (510.8 +/- 33 vs 292.4 +/- 29).

16 orionic gonadotropin (hCG) 151,111 IU/L, and lactate dehydrogenase 588 U/L.

17 Lactate dehydrogenase A (LDH-A) catalyzes the interconve

18 regulation of heat shock factor 1 (HSF1) and lactate dehydrogenase A (LDH-A) in ErbB2-positive cancer

19 of the genes encoding hexokinase 1 (HK1) and lactate dehydrogenase A (LDHA) - both of which regulate

20 Lactate dehydrogenase A (LDHA) catalyzes the conversion

21 ing hematopoietic stem cells (HSCs), whereas lactate dehydrogenase A (LDHA) deletion significantly in

22 Lactate dehydrogenase A (LDHA) has been reported to be i

23 Here, we show that lactate dehydrogenase A (LDHA) is induced in activated T

24 t that phosphorylation-induced activation of lactate dehydrogenase A (LDHA), an enzyme that catalyses

25 housekeeping genes - such as those encoding lactate dehydrogenase A (LDHA), solute transporter MCT1,

26 f pyruvate dehydrogenase kinase 1 (PDK1) and lactate dehydrogenase A (LDHA).

27 lpha including those involved in glycolysis (lactate dehydrogenase A and enolase 2), oxidant stress (

28 to the hypoxia response element site in the lactate dehydrogenase A and PKM2 loci and mediates the r

29 Small interfering RNA ablation of lactate dehydrogenase A attenuated HDM-induced increases

30 er HIF-1-regulated promoter derived from the lactate dehydrogenase A gene.

31 ycolytic enzymes, with notable expression of lactate dehydrogenase A occurring in the airway epitheli

32 is enzymes pyruvate dehydrogenase kinase and lactate dehydrogenase A within cortical and hippocampal

33 nown biomarkers of acidity, such as hypoxia, lactate dehydrogenase A, and CAIX.

34 a targets VEGF-A, glucose transporter-1, and lactate dehydrogenase A.

35 ed the contributions of macrophage-expressed lactate dehydrogenase-A (LDH-A) to tumor formation in a

36 Lactate dehydrogenase-A (LDH-A), responsible for convers

37 ntially metabolized to lactate by the enzyme lactate dehydrogenase-A (LDH-A), suggesting a possible v

38 /fructose-2,6-bisphosphatase-3 (PFKFB3), and lactate dehydrogenase-A expression.

39 re, we show that pharmacologic inhibition of lactate dehydrogenase-A suppressed the conversion of hyp

40 genes driving aerobic glycolysis, including lactate dehydrogenase-A that generates lactate.

41 PL flux correlated significantly with higher lactate dehydrogenase activity and mRNA expression of Ld

42 cantly increased NO production and decreased lactate dehydrogenase activity compared with CMs alone.

43 atinocytes, as established by the release of lactate dehydrogenase activity from the cytoplasm of the

44 phorylation, and NO production and decreased lactate dehydrogenase activity in the presence of HG.

45 m by visualizing, for example, the augmented lactate dehydrogenase activity in tumor cells.

46 associated with changes in levels of NADH or lactate dehydrogenase activity in tumors.

47 coenzyme-A dehydrogenase activity and higher lactate dehydrogenase activity in VD-deficient animals.

48 The ratio between the free and the total lactate dehydrogenase activity is a promising predictive

49 Lactate dehydrogenase activity was also positively corre

50 t although fetal plasma fructose and hepatic lactate dehydrogenase activity were greater in cortisol-

51 d production of hydrogen peroxide, decreased lactate dehydrogenase activity, and increased sensitivit

52 tissue compared to the cell-line, a loss of lactate dehydrogenase activity, but not of alpha-d-gluco

53 Difference became evident in the lactate dehydrogenase activity, left ventricular weight,

54 eolar lavage fluid protein concentration and lactate dehydrogenase activity, lung weight gain, and in

55 une checkpoint pathways and greater rates of lactate dehydrogenase activity.

56 ion injury, involving attenuated variable of lactate dehydrogenase, alanine, aspartate, and cytokine

57 validated: performance status (PS), albumin, lactate dehydrogenase, alkaline phosphatase, number of m

58 0 had a toxic effect, as seen by assays with lactate dehydrogenase and 3-(4,5-dimethylthiazol-2-yl)-2

59 ars was 62% in patients with normal baseline lactate dehydrogenase and 63% in patients with a complet

60 p until the end of treatment (a total of 137 lactate dehydrogenase and 77 neuron-specific enolase obs

61 Cellular injury markers lactate dehydrogenase and aspartate aminotransferase wer

62 , lower hemoglobin and platelets, and higher lactate dehydrogenase and beta-2-microglobulin.

63 associated with hemolytic parameters such as lactate dehydrogenase and bilirubin and negatively with

64 asured by optical imaging and by analysis of lactate dehydrogenase and caspase-cleaved cytokeratin 18

65 enhanced native refolding of urea-denatured lactate dehydrogenase and heat-denatured glucose-6-phosp

66 This process was accomplished by deletion of lactate dehydrogenase and heterologous expression of a C

67 The effect of freeze-thawing on cytosolic lactate dehydrogenase and lysosomal alpha-d-glucosidase

68 rogenase, whereas l-(S)-2-HG is generated by lactate dehydrogenase and malate dehydrogenase in respon

69 ncluding enolase, pyruvate kinase M2 (PKM2), lactate dehydrogenase and monocarboxylate transporter.

70 d extractions, multienzyme systems linked to lactate dehydrogenase and NAD(+) generation, and HPLC-ba

71 lene green) and a hydrogel matrix containing lactate dehydrogenase and nicotinamide adenine dinucleot

72 herapy predicted inferior PFS, and increased lactate dehydrogenase and poor Eastern Cooperative Oncol

73 her protein carbonyls, 3-nitrotyrosine, PAR, lactate dehydrogenase and proteins in bronchoalveolar la

74 PEB1 aspartate/glutamate transporter, LutABC lactate dehydrogenase and PutA proline dehydrogenase bec

75 Cell viability was assayed by lactate dehydrogenase and thiazolyl blue tetrazolium bro

76 e D(-)-lactate by deleting the native ldh (L-lactate dehydrogenase) and alsS (acetolactate synthase)

77 ed indices of organ damage (transaminasemia, lactate dehydrogenase) and increased mortality.

78 membrane-bound respiratory enzymes, LdhD (D-lactate dehydrogenase) and LldD (L-lactate dehydrogenase

79 ed that cytoplasmic LdhA (NAD(+)-dependent D-lactate dehydrogenase) and the membrane-bound respirator

80 nce status >1, extranodal sites >1, elevated lactate dehydrogenase, and B symptoms at diagnosis were

81 serum creatinine, alanine aminotransferase, lactate dehydrogenase, and creatine kinase.

82 ating levels of alanine aminotransferase and lactate dehydrogenase, and inflammatory mediators such a

83 photoactivation of labeled GAPDH, aldolase, lactate dehydrogenase, and pyruvate kinase revealed not

84 e pathways, such as glycolysis, flux through lactate dehydrogenase, and the citric acid cycle (as inf

85 ion or 11q deletion by FISH, increased serum lactate dehydrogenase, and unmutated IGHV mutation statu

86 significant changes in Bak-1, Bcl-2, Bcl-xL, lactate dehydrogenase, annexin V, and propidium iodide)

87 , LdhD (D-lactate dehydrogenase) and LldD (L-lactate dehydrogenase) are correctly annotated.

88 Whereas initial high blood counts and high lactate dehydrogenase as an indicator for high prolifera

89 ADH Sink" was created using Escherichia coli lactate dehydrogenase as an NADH scavenger, thereby prev

90 Aspartate aminotransferase and lactate dehydrogenase as injury markers were below the d

91 he Ldhb gene, which encodes the H isoform of lactate dehydrogenase, as a robust PPARgamma target in t

92 evidenced by increased creatinine kinase and lactate dehydrogenase, as well as expression of monocyte

93 Neo1 mice showed attenuated serum levels of lactate dehydrogenase, aspartate, alanine, and proinflam

94 s evaluated using histology, serum levels of lactate dehydrogenase, aspartate, and alanine aminotrans

95 rfusion injury, as measured by the levels of lactate dehydrogenase, aspartate, and alanine aminotrans

96 Lactate dehydrogenase assay (LDH), electronic microscopy

97 ucing sugars and phenolic compounds, and the lactate dehydrogenase assay was invalidated by honey oxi

98 almonella mutation assays) and cytotoxicity (lactate dehydrogenase assay) to assess the toxicity of t

99 Cell toxicity was measured using a lactate dehydrogenase assay.

100 Cell death was determined by using the lactate dehydrogenase assay.

101 measured by sulforhodamine B assay and also lactate dehydrogenase assay: meanwhile, changes in the s

102 P. gingivalis supernatant was measured with lactate dehydrogenase assays.

103 Lactate dehydrogenase B (LDHB) showed the highest combin

104 Using this approach, we identify lactate dehydrogenase B (LDHB), a component of glycolyti

105 phosphate-dehydrogenase, alpha enolase and L-lactate dehydrogenase B-chain) and in oxidative stress (

106 icotinamide adenine dinucleotide), even with lactate dehydrogenase blocked to prevent lactate generat

107 o demonstrate that the reaction landscape of lactate dehydrogenase branches at multiple points creati

108 generated by the reduction of pyruvate via l-lactate dehydrogenase, but this enzyme does not efficien

109 Other factors, such as lactate dehydrogenase, circulating myeloblasts, platelet

110 he cytotoxicity of MVS was evaluated using a lactate dehydrogenase colorimetric assay.

111 Diagnosis with PfHRP2/Pf-Plasmodium lactate dehydrogenase combination RDTs did not select fo

112 d be moderated by using PfHRP2/Pf-Plasmodium lactate dehydrogenase combination RDTs.

113 The patient's lactate dehydrogenase concentration was 327 U/L (normal

114 n was stratified by ECOG performance status, lactate dehydrogenase concentration, and BRAF(V600) muta

115 urvival when adjusted for sex, age, baseline lactate dehydrogenase concentration, comorbidity, mono-o

116 ns resulted in the dose dependent release of lactate dehydrogenase, confirming the direct interaction

117 d-Lactate dehydrogenase (d-LDH) is encoded by a single gen

118 in its reductase domain similar to that of D-lactate dehydrogenase (D-LDH).

119 he mitochondrial respiratory chain via the D-lactate dehydrogenase Dld1.

120 ting expression of the Drosophila homolog of lactate dehydrogenase (dLdh).

121 Recombinant COR15 proteins stabilize lactate dehydrogenase during freezing in vitro.

122 ed International Prognostic Index, including lactate dehydrogenase, Eastern Cooperative Oncology Grou

123 Dld2 and Dld3, both currently annotated as D-lactate dehydrogenases, efficiently oxidized D-2HG to al

124 ucation, hemoglobin A1C, C-reactive protein, lactate dehydrogenase, electrolytes, or urine albumin.

125 It was shown that infection of mice with lactate dehydrogenase-elevating virus (LDV) impairs earl

126 In this article, we show that infection with lactate dehydrogenase-elevating virus, a benign mouse ar

127 However, the lactate dehydrogenase-elevating virus-induced exacerbati

128 n and functionalized with glutaraldehyde and lactate dehydrogenase enzyme was immobilized on the alde

129 jump results yields an unprecedented view of lactate dehydrogenase enzymology, confirming the timesca

130 variate analysis, including IPSS, WPSS, age, lactate dehydrogenase, ferritin concentration, Eastern C

131 K2 is a 48-residue protein that can protect lactate dehydrogenase from freeze-thaw damage by prevent

132 nd dehydrin size on their ability to protect lactate dehydrogenase from freeze-thaw damage.

133 We show here that d-lactate dehydrogenase from Staphylococcus epidermidis re

134 With syngas, the upregulated (R)-lactate dehydrogenase gene represents a route of electro

135 l involvement 52%, Performance Status > 16%, lactate dehydrogenase > 1N 38%, Mantle Cell Lymphoma Int

136 60-10.948; P < .001), and elevated levels of lactate dehydrogenase (>1200 U/L; OR, 2.620; 95% CI, 1.0

137 Multivariate analysis showed high lactate dehydrogenase, >/=3 prior treatment lines, and l

138 regular need for pain medication, and higher lactate dehydrogenase had a negative impact on the thera

139 d creatinine, gamma-glutamyl transpeptidase, lactate dehydrogenase, histologic parameters, macrophage

140 Human lactate dehydrogenase (hLDH5), a glycolytic enzyme respo

141 tio [HR], 2.3; 95% CI, 1.6 to 3.4), elevated lactate dehydrogenase (HR, 2.3; 95% CI, 1.4 to 3.8), B s

142 of a dual-band (histidine-rich protein-2/pan-lactate dehydrogenase [HRP2/pLDH]) rapid diagnostic test

143 ; lymphopenia in 45%; and elevated levels of lactate dehydrogenase in 82%, aspartate aminotransferase

144 A), toxicity assays in cell culture (MTT and lactate dehydrogenase in human SH-SHY5Y cells, mouse neu

145 erexpression of a Lactobacillus helveticus L-lactate dehydrogenase in M. buryatense resulted in an in

146 Increased release of lactate dehydrogenase in OmpU-treated cells indicates th

147 biosensor was developed for the detection of lactate dehydrogenase in serum using a nonporous, oxygen

148 indicated by elevated levels of albumin and lactate dehydrogenase in the BAL fluid.

149 Stx2 induced the release of hemoglobin and lactate dehydrogenase in whole blood, indicating hemolys

150 Administration of a lactate dehydrogenase inhibitor blunted lactate producti

151 This effect was followed by a decrease in lactate dehydrogenase isoform M (LDH-M) activity and an

152 luate the selectivity of this process, human lactate dehydrogenase isozyme 1 (LDH-1) microcrystals we

153 Cerebrospinal fluid lactate dehydrogenase isozyme 5, beta2-microglobulin, an

154 Therefore, interpreting T-jump results of lactate dehydrogenase kinetics has required extensive co

155 biomarkers of defense (superoxide dismutase, lactate dehydrogenase, laccase) and damage (thiobarbitur

156 ncrease in bronchoalveolar protein (48%) and lactate dehydrogenase (LDH) (68%) following 72 hours of

157 cellular lactate in all cases, and unchanged lactate dehydrogenase (LDH) activity and increased NAD+/

158 Lactate dehydrogenase (LDH) and NAD(+) were subsequently

159 Next, genes encoding lactate dehydrogenase (ldh) and pyruvate oxidase (poxB)

160 Via immobilization of lactate dehydrogenase (LDH) as a model dehydrogenase enz

161 We identified lactate dehydrogenase (LDH) as a new functional target o

162 Cellular viability, autophagy, lactate dehydrogenase (LDH) assay, and mammalian target

163 in skeletal muscle drives the expression of lactate dehydrogenase (LDH) B in an estrogen-related rec

164 Patients with normal lactate dehydrogenase (LDH) concentration and fewer than

165 We measured lactate dehydrogenase (LDH) concentration as a marker of

166 The release of lactate dehydrogenase (LDH) during brain death was reduc

167 g simulations have proposed that human heart lactate dehydrogenase (LDH) employs protein promoting vi

168 d to three independent prognostic variables: lactate dehydrogenase (LDH) higher than than normal, Int

169 titanium oxynitride (TiON) were modified for lactate dehydrogenase (LDH) immobilization using (3-amin

170 Lactate dehydrogenase (LDH) is an enzyme involved in ana

171 Catalytic turnover of pyruvate to lactate by lactate dehydrogenase (LDH) is critical in maintaining a

172 We demonstrate that lactate dehydrogenase (LDH) isoform 5 secreted by gliobl

173 In addition, FBSH-III inhibited lactate dehydrogenase (LDH) leakage and intracellular re

174 lar health and integrity: cell viability and lactate dehydrogenase (LDH) leakage.

175 A biomarker panel using CTC count and lactate dehydrogenase (LDH) level was shown to satisfy t

176 ndings of elevated D-dimer level or elevated lactate dehydrogenase (LDH) level were suspected of embo

177 m glutamate pyruvate transaminase (SGPT) and lactate dehydrogenase (LDH) levels along with reduction

178 e occurrence of pump thrombosis and elevated lactate dehydrogenase (LDH) levels, LDH levels presaging

179 ystemic treatment, M1 subclass, and baseline lactate dehydrogenase (LDH) levels.

180 in the cytosol is oxidized by mitochondrial lactate dehydrogenase (LDH) of the same cell.

181 ry, which was manifest as reduced myocardial lactate dehydrogenase (LDH) release and infarct size and

182 ,5-diphenyl tetrazolium bromide (MTT) assay, lactate dehydrogenase (LDH) release assay, Hoechst 33342

183 one, conjugates did not induce a significant lactate dehydrogenase (LDH) release from Calu-3 cells af

184 re, the effect of 7l,q,r, and 8i in lowering lactate dehydrogenase (LDH) release induced by ischemia-

185 cordings, and cell death was quantified with lactate dehydrogenase (LDH) release measurements and Nis

186 rmeability transition pore (MPTP) formation, lactate dehydrogenase (LDH) release, and necrotic cell d

187 e stress, and apoptosis were evaluated using lactate dehydrogenase (LDH) release, the fluorescent pro

188 unction (assessed by JC-1 fluorescence), and lactate dehydrogenase (LDH) release.

189 y pharmacological inhibition of hypothalamic lactate dehydrogenase (LDH) suggesting that metabolic fl

190 ter CD138 plasma cell purification and serum lactate dehydrogenase (LDH) to evaluate their prognostic

191 on reduced graphene oxide (RGO-AuNPs) and l-lactate dehydrogenase (LDH) was developed for the sensin

192 Serum containing lactate dehydrogenase (LDH) was directly spotted on to t

193 s greater than 55 mg/dL (LR range, 7.1-250), lactate dehydrogenase (LDH) was greater than 200 U/L (LR

194 in, 3.4 g/dL; beta2-microglobulin, 5.7 mg/L; lactate dehydrogenase (LDH), 397 IU/L; and normal liver

195 The up-regulation of L-lactate dehydrogenase (LDH), an intracellular enzyme pre

196 UT-1 and GLUT-3), phosphofructokinase (PFK), lactate dehydrogenase (LDH), and adenosine monophosphate

197 Two cell viability assays, MTT and lactate dehydrogenase (LDH), and an assay measuring cyto

198 Live/dead, lactate dehydrogenase (LDH), and caspases-3/-7 assays de

199 requency of lymphocytosis, elevated level of lactate dehydrogenase (LDH), and p53 positivity.

200 (ALT), gamma glutamyltransferase (gammaGT), lactate dehydrogenase (LDH), and phosphatase alkaline (P

201 ected to determine differential cell counts, lactate dehydrogenase (LDH), and protein.

202 years), stage (I/II v III/IV), primary site, lactate dehydrogenase (LDH), bone marrow/CNS (BM/CNS) in

203 fluid (BALF) was analysed for total protein, lactate dehydrogenase (LDH), CXCL1/KC, CCL2/MCP-1 and di

204 yruvate and endogenous lactate, catalyzed by lactate dehydrogenase (LDH), has proved to be a powerful

205 fusate biomarkers glutathione S-transferase, lactate dehydrogenase (LDH), heart-type fatty acid bindi

206 Five predictors (age, lactate dehydrogenase (LDH), sites of involvement, Ann A

207 There was no significant change in lactate dehydrogenase (LDH), total protein, and total ce

208 occal virulence, we investigated the role of lactate dehydrogenase (LDH), which converts pyruvate to

209 d for shorter PFS in patients with increased lactate dehydrogenase (LDH).

210 ttributed to the terminal glycolytic enzyme, lactate dehydrogenase (LDH).

211 series of pyrazole-based inhibitors of human lactate dehydrogenase (LDH).

212 HO performance status (0 v 1 or 2) and serum lactate dehydrogenase (LDH; </= v > 1.5x the upper limit

213 entional melanoma serum biomarkers (S100 and lactate dehydrogenase [LDH]) perform poorly in patients

214 um) and enzymes (alcohol dehydrogenase, ADH; lactate dehydrogenase, LDH; xanthine oxidase, XOx; gluco

215 The parasite genome encodes two isoforms of lactate dehydrogenase (LDH1 and LDH2) and enolase (ENO1

216 n of the Hypoxia Inducible Factor HIF1alpha, lactate dehydrogenase LDH5, glucose transporter GLUT2, p

217 found that the loss of hexokinase (HK2) and lactate dehydrogenase (LDHA) expression, together with a

218 tion of pyruvate to or expression of mifR in lactate dehydrogenase (ldhA) mutant biofilms did not res

219 -annotated, respiratory, and substrate-level lactate dehydrogenases (LDHs) from the obligate human pa

220 in sequence and catalytic properties, the l-lactate dehydrogenases (LDHs) in lactic acid bacteria (L

221 d to the cytosol and converted to oxalate by lactate dehydrogenase, leading to kidney failure.

222 Cell injury was assessed by lactate dehydrogenase leakage and propidium iodide uptak

223 id-induced acinar cell injury as measured by lactate dehydrogenase leakage and propidium iodide uptak

224 tight junctions was tested by measuring the lactate dehydrogenase leakage and transepithelial electr

225 Under hypoxic conditions, cellular damage (lactate dehydrogenase leakage), apoptosis (terminal deox

226 R, 1.79; 95% CI ,1.35-2.38), and an elevated lactate dehydrogenase level (HR, 1.87; 95% CI, 1.27-2.77

227 pecific antigen level (r = 0.556, P < .001), lactate dehydrogenase level (r = 0.534, P < .001), alkal

228 and multivariable analysis, increased serum lactate dehydrogenase level and histology for a metastat

229 Multivariate analysis identified serum lactate dehydrogenase level and the NOTCH1/FBXW7/RAS/PTE

230 LLH was defined by a discharge lactate dehydrogenase level of 400 to 700 U/L.

231 LL, the four-gene oncogenetic classifier and lactate dehydrogenase level were independent prognostic

232 Altered performance status, anemia, high lactate dehydrogenase level, "B" symptoms, histologic gr

233 ed with adverse prognostic factors (ie, high lactate dehydrogenase level, 17p deletion, and high-risk

234 se level, 1435 U/L (normal level, <140 U/L); lactate dehydrogenase level, 253 U/L (normal level, <240

235 stituting the MIPI, age, performance status, lactate dehydrogenase level, and WBC count, were confirm

236 tumor stage, tumor location (leg vs nonleg), lactate dehydrogenase level, type of therapy (with or wi

237 hypoalbuminemia, thrombocytopenia, and high lactate dehydrogenase level, yielded a better C statisti

238 iate analysis including M substage and serum lactate dehydrogenase level.

239 d brain metastases (20% v 14%) and increased lactate dehydrogenase levels (52% v 38%) at baseline; 41

240 HR 2.09; 95% CI 1.20-3.65; P = .010), higher lactate dehydrogenase levels (HR per mg/dL 1.002; 95% CI

241 and was significantly associated with lower lactate dehydrogenase levels (P = .002).

242 ry bypass (R = 0.12 and 0.15, respectively), lactate dehydrogenase levels at end cardiopulmonary bypa

243 The lactate dehydrogenase levels were increased nearly 2- an

244 a decrease in hematocrit, and elevated serum lactate dehydrogenase levels were observed.

245 blood cell count, blast cells, splenomegaly, lactate dehydrogenase levels, and bone pain.

246 ia, elevated serum beta(2)-microglobulin and lactate dehydrogenase levels, as well as impaired renal

247 rum creatinine level > 133 mumol/L, elevated lactate dehydrogenase levels, disseminated lymphoma, bra

248 ed bilirubin levels or clinical icterus, and lactate dehydrogenase levels.

249 tate aminotransferase were persistently low (lactate dehydrogenase < 100 U/L, below analyzer range; a

250 In conclusion, lactate dehydrogenase may be used as a marker to both as

251 Malate and lactate dehydrogenases (MDH and LDH) are homologous, cor

252 etrazolium-bromide cell viability assay, the lactate dehydrogenase membrane leakage assay and nitric

253 In patients with elevated serum lactate dehydrogenase (n = 84), median PFS and OS were l

254 Among these peptides, two were derived from lactate dehydrogenase, one from creatine kinase, and fou

255 logy Group performance status, disease site, lactate dehydrogenase, opioid analgesic use, albumin, he

256 ma exchange/infusion use, platelet count, or lactate dehydrogenase or haptoglobin levels.

257 teristic radiographic findings with elevated lactate dehydrogenase, or hospitalization for pneumonia

258 (nonbulky stage II, age >60 years, elevated lactate dehydrogenase, or World Health Organization perf

259 lactate transport (4CIN), or an inhibitor of lactate dehydrogenase, oxamate (OX), into the VMH prior

260 duction of pancreatic IRI, serum amylase and lactate dehydrogenase peaked at 6 hr and returned to bas

261 rich protein II (PfHRP-II) and P. falciparum lactate dehydrogenase (PfLDH) antigens are widely deploy

262 le-antigen (histidine-rich protein 2 and pan-lactate dehydrogenase pLDH [HRP2/pLDH]) RDT and microsco

263 idine-rich protein-II (HRPII) and Plasmodium lactate dehydrogenase (pLDH).

264 ger tumors, decreased body weight, increased lactate dehydrogenase production, and severe leukopenia.

265 city), lung weight gain, levels of proteins, lactate dehydrogenase, protein carbonyl (marker of ROS),

266 Elevated lactate dehydrogenase, proteinuria on routine urinalysis

267 riables at diagnosis (age, serum creatinine, lactate dehydrogenase, PTLD localization, and histology)

268 Utilizing lactate dehydrogenase release and live/dead cell cytotox

269 tingly, even higher toxicity was measured by lactate dehydrogenase release and terminal deoxynucleoti

270 cellular cytotoxicity (RMCC) was assessed by lactate dehydrogenase release assay of CD20+ Daudi cells

271 is-infected cells analyzed on the basis of a lactate dehydrogenase release assay, propidium iodide st

272 Lactate dehydrogenase release assays demonstrated that p

273 Results from lactate dehydrogenase release assays showed a dose- and

274 ability was assessed by tetrazolium salt and lactate dehydrogenase release assays.

275 city, as measured both by (51)Cr release and lactate dehydrogenase release assays.

276 reflected by augmented caspase 3/7 activity, lactate dehydrogenase release from cells, and an increas

277 Abeta-induced dendritic spine loss and lactate dehydrogenase release required both PrP(C) and F

278 No significant lactate dehydrogenase release was found after P. gingiva

279 A significant increase of lactate dehydrogenase release was observed, especially a

280 interleukin-1beta [IL-1beta] secretion, and lactate dehydrogenase release) compared to that with the

281 diphenyltetrazolium bromide (MTT) reduction, lactate dehydrogenase release, and [(3)H]choline uptake

282 namide adenine dinucleotide epifluorescence, lactate dehydrogenase release, and electron microscopy,

283 feration of prostate carcinoma cells, led to lactate dehydrogenase release, and induced apoptosis.

284 exposure increased the number of dead cells, lactate dehydrogenase release, and interleukin-8 (IL-8)

285 ecreased Trypan blue exclusion and increased Lactate dehydrogenase release.

286 xic effects of EMD treatment were sampled by lactate dehydrogenase release.

287 demonstrated significantly higher values of lactate dehydrogenase resembling cell damage (P=0.02), h

288 dehydrogenase, D-glucose dehydrogenase and L-lactate dehydrogenase respectively.

289 bstrates for yeast alcohol dehydrogenase and lactate dehydrogenase, respectively, with reaction rates

290 The readthrough-extended lactate dehydrogenase subunit LDHBx can also co-import L

291 +), an essential co-enzyme for mitochondrial lactate-dehydrogenase that converts lactate into pyruvat

292 , creatinine kinase, C-reactive protein, and lactate dehydrogenase to those seen in H5N1 patients, wh

293 We aimed to assess if the simple formula-lactate dehydrogenase (U/L) x creatinine (mg/dL)/thrombo

294 Increased lactate dehydrogenase was associated with increased risk

295 , which can be converted back to pyruvate by lactate dehydrogenase, was also addressed.

296 The outflow of a cytosolic enzyme, lactate dehydrogenase, was studied in sea bream fillets

297 age, performance status, serum ferritin, and lactate dehydrogenase were significant additive features

298 on of Na(+), proteinuria, or serum levels of lactate dehydrogenase were similar in both groups.

299 rs, large-cell transformation, and increased lactate dehydrogenase) were independent prognostic marke

300 tate dehydrogenase (5 years, 45%) and normal lactate dehydrogenase with fewer than three organ sites